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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
190 Results for "
Nitro
" in MedChemExpress (MCE) Product Catalog:
Products (190)
190 Results for "Nitro" in MCE Product Catalog:
Cat. No.: HY-N11009
CAS No.: 942612-74-0
Category:
Triterpenes Terpenoids Cucurbitaceae Extract Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants
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Antipain dihydrochloride is a protease inhibitor isolated from Actinomycetes. Antipain dihydrochloride inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations. Antipain dihydrochloride restricts uterine DNA synthesis and function in mice .
Cat. No.: HY-127039
CAS No.: 37691-11-5
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Antipain is a protease inhibitor isolated from Actinomycetes. Antipain inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations. Antipain restricts uterine DNA synthesis and function in mice .
Cat. No.: HY-176183
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STING ligand-4 (Compound 2) is a nitro-free covalent STING inhibitor with an IC50 < 0.2 μM. STING ligand-4 can be used for synthesis of PROTAC STING degrader-4 (HY-176180) .
Cat. No.: HY-E71533
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2-Furoyl-CoA dehydrogenase (EC 1.3.99.8) is a copper protein. Acceptors for 2-furoyl-CoA dehydrogenase (EC 1.3.99.8) include methylene blue, nitro blue tetrazolium, and membrane components of Pseudomonas putida.
Cat. No.: HY-W587874
CAS No.: 730-40-5
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Disperse Orange 3 is a monoazo dye characterized by a dye content of 90% along with dispersing agents and surfactants; it features two aromatic rings, one of which possesses an amino group while the other is modified with a nitro group, exhibiting a prominent absorption peak at 415 nm.
Cat. No.: HY-163292
CAS No.: 3029324-01-1
Antibacterial agent 180 (15g), an appropriate substrate for the type I nitro reductases (TcNTR I), is a promising antitrypanosomatid agent. Antibacterial agent 180 (15g) shows nonmutagenic potential against Salmonella typhimurium strains (TA98, TA100, and TA102) .
Cat. No.: HY-169438
CAS No.: 2097636-47-8
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NNISC-2 (compound 4) is a DNA intercalator-linker conjugate of Naph-Se-TMZ (HY-169433), which is composed of DNA intercalator (blue part) Nitro-Naphthalimide-C2-acylamide (HY-169437) and a linker (black part) .
Cat. No.: HY-W010132
CAS No.: 94-52-0
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5-nitrobenzimidazole is a genotoxic nitro compound and 6-aminopurine (HY-B0152) analogue. 5-nitrobenzimidazole shows a slight inhibitory effect on xanthine oxidase, with an IC50 of 86.84 μM. 5-nitrobenzimidazole can be used in the research of hyperuricemia .
Cat. No.: HY-206852
CAS No.: 2055777-51-8
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PF-06445974 precursor (Compound 28) is a nitro precursor and synthetic intermediate. PF-06445974 precursor can be used for the synthesis of PF-06445974 (HY-119190). PF-06445974 is a positron emission tomography (PET) compound that acts potently on PDE4B .
Cat. No.: HY-101559S
CAS No.: 2749984-40-3
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RA375 is a RPN13 (26S proteasome regulatory subunit) inhibitor. RA375 activates UPR signaling, ROS production and apoptosis. RA375 exhibits ten-fold greater activity against cancer lines than RA190, reflecting its nitro ring substituents and the addition of a chloroacetamide warhead .
Cat. No.: HY-105129AS
CAS No.: 2468639-37-2
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4-Phenyl-7,8-dihydroxycoumarin is a coumarin-based non-nitro catechol-type COMT inhibitor with an IC50 of 1.8 μM against rat S-COMT. 4-Phenyl-7,8-dihydroxycoumarin can be used in studies on the binding mechanism of COMT inhibitors and Parkinson's disease .
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Disperse red 167:1 (DR 167:1) is an azo disperse dye . Disperse red 167:1 interacts with the active site of nitroreductase, leading to the reduction of its nitro group to amine metabolites. Disperse red 167:1 is mainly used for dyeing hydrophobic fibers such as polyester, and is also applicable to dyeing research on plastics, textiles and other materials .
Cat. No.: HY-105129AR
CAS No.: 70132-50-2
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Pimonidazole (Standard) is the analytical standard of Pimonidazole. This product is intended for research and analytical applications. Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor . Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia .
Cat. No.: HY-105129R
CAS No.: 70132-51-3
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Pimonidazole (hydrochloride) (Standard) is the analytical standard of Pimonidazole (hydrochloride). This product is intended for research and analytical applications. Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor . Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia .
Cat. No.: HY-W325356
CAS No.: 5342-97-2
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Tert-butyl 3,5-dinitrobenzoate is an intermediate or reactant in organic synthesis and can also play a role in drug synthesis, dye preparation and other chemical fields.The nitro functional group of Tert-butyl 3,5-dinitrobenzoate has certain reactivity in organic chemistry and can participate in various reactions, such as electrophilic substitution, aromatic amine reaction, etc .
Cat. No.: HY-101761A
CAS No.: 2319722-53-5
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TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 μM. TM5441 induces intrinsic apoptosis in several human cancer cell lines. TM5441 attenuates Nω-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
