9 Results for "

18β-Glycyrrhetinic acid

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "18β-Glycyrrhetinic acid" in MCE Product Catalog:

16
16 Publications Verification
Cat. No.: HY-N0180
CAS No.: 471-53-4
18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhiza uralensis and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties.
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Cat. No.: HY-N0180R
CAS No.: 471-53-4
18β-Glycyrrhetinic acid (Standard) is the analytical standard of 18β-Glycyrrhetinic acid. This product is intended for research and analytical applications. 18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhiza uralensis and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties.
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Cat. No.: HY-N0180S
18β-Glycyrrhetinic acid-d3 is deuterium labeled 18β-Glycyrrhetinic acid. 18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhizae Radix and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties.
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Cat. No.: HY-145853
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

GA-O-02, a 18β-Glycyrrhetinic acid derivative, is a potent antimicrobial and anti-inflammatory agent. GA-O-02 exerts anti-inflammation through the inhibition of NO, pro-inflammatory cytokines and chemokines. GA-O-02 displays a high antimicrobial activity against Gram-positive bacteria .
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Cat. No.: HY-145854
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

GA-O-06, a 18β-Glycyrrhetinic acid derivative, is a potent antimicrobial and anti-inflammatory agent. GA-O-06 exerts anti-inflammation through the inhibition of NO, pro-inflammatory cytokines and chemokines. GA-O-06 displays a high antimicrobial activity against Gram-positive bacteria .
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Cat. No.: HY-N0375A
CAS No.: 90365-60-9
3-epi-18β-Glycyrrhetinic acid is an inhibitor of 11β-HSD1 and 11β-HSD2, with an IC50 of 0.17 μM against 11β-HSD2. 3-epi-18β-Glycyrrhetinic acid acts as a weak substrate for sulfotransferase 2A1. It serves as a biomarker for the toxicity of licorice-related pseudoaldosteronism. 3-epi-18β-Glycyrrhetinic acid is applicable to studies related to pseudoaldosteronism .
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Cat. No.: HY-149017
CAS No.: 2252278-57-0
Target:  

Apoptosis

Research Areas:  

Cancer

Apoptosis inducer 7 (Compound 5I) induces apoptosis in cancer cells. Apoptosis inducer 7 inducrs cleavage of PARP, caspases, down-regulation of anti-apoptotic protein c-Flip and up regulation of pro-apoptotic protein Noxa. Apoptosis inducer 7 exhibits antitumor activity .
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Cat. No.: HY-W755367
CAS No.: 1477-44-7
Target:  

11β-HSD

Research Areas:  

Others

Methyl glycyrrhetinate, a 18β-glycyrrhetinic acid analogue, is a dual inhibitor of 11β-HSD1 and 11β-HSD2 .
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Cat. No.: HY-133147
CAS No.: 2417510-17-7
Target:  

HDAC Apoptosis

Research Areas:  

Cancer

HDAC3/6-IN-2 (compound 15) is a potent HDAC6 and HDAC3 inhibitor, with IC50 values of 0.368 and 0.635 μM, respectively. HDAC3/6-IN-2 shows antitumor activity, and induces cancer cell apoptosis. HDAC3/6-IN-2 decreases the levels of HDAC6 and HDAC3, associated with upregulation of acetylated H3 and α-tubulin .
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