Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
2'-3'-cyclic GMP-AMP
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "2'-3'-cyclic GMP-AMP" in MCE Product Catalog:
44
44 Publications Verification
Synonyms: 2'-3'-cyclic GMP-AMP
Target:
44
44 Publications Verification
Synonyms: 2'-3'-cyclic GMP-AMP sodium
Target:
28
28 Cited Publications
Synonyms: cyclic GMP-AMP; 3',3'-cGAMP
Target:
Research Areas:
cGAMP (Cyclic GMP-AMP) functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators [3] .
28
28 Cited Publications
Synonyms: cyclic GMP-AMP disodium; 3',3'-cGAMP disodium
Category:
Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
28
28 Cited Publications
Cat. No.: HY-110385A
Purity: 95.19%
Synonyms: cyclic GMP-AMP diammonium; 3',3'-cGAMP diammonium
Target:
3
3 Cited Publications
Cat. No.: HY-P72337
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CGAS; D4; Prev. C6orf150; DANGER Family Member 4; Prev. MB21D1; CGAMP Synthase; H-CGAS; Chromosome 6 Open Reading Frame 150; Mab-21 Domain-Containing Protein 1; Protein MB21D1; 2'3'-CGAMP Synthase; cyclic GMP-AMP Synthase; Mab-21 Domain Containing 1
Species:
Human
Source:
E. coli
1
Target:
1
1 Cited Publications
Target:
1
1 Cited Publications
Cat. No.: HY-P71597
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CGAS; D4; Prev. C6orf150; DANGER Family Member 4; Prev. MB21D1; CGAMP Synthase; H-CGAS; Chromosome 6 Open Reading Frame 150; Mab-21 Domain-Containing Protein 1; Protein MB21D1; 2'3'-CGAMP Synthase; cyclic GMP-AMP Synthase; Mab-21 Domain Containing 1
Species:
Human
Source:
E. coli
Cat. No.: HY-100564BS
Synonyms: 2'-3'-cyclic GMP-AMP-d8 ammonium
Research Areas:
2',3'-cGAMP-d8 (2'-3'-Cyclic GMP-AMP-d8) ammonium is the deuterated-labeled 2',3'-cGAMP ammonium. 2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm .
Cat. No.: HY-162459
CAS No.: 3036368-70-1
Target:
Research Areas:
cGAS-IN-3 (compound 30d-S) is an orally active cyclic GMP-AMP synthase (Cyclic GMP-AMP Synthase/cGAS) inhibitor with good plasma exposure and low clearance. cGAS-IN-3 has anti-inflammatory activity and can significantly reduce lung inflammation in rats .
Cat. No.: HY-113469B
Purity: 99.07%
Target:
Research Areas:
Cyclic GMP (cGMP) TBAOH, an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP TBAOH occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses [3] .
Cat. No.: HY-113469R
CAS No.: 7665-99-8
Cat. No.: HY-100564AR
CAS No.: 2734858-36-5
Synonyms: 2'-3'-cyclic GMP-AMP sodium (Standard)
Category:
Cat. No.: HY-100564R
CAS No.: 1441190-66-4
Synonyms: 2'-3'-cyclic GMP-AMP (Standard)
Category:
Cat. No.: HY-12512R
CAS No.: 849214-04-6
Synonyms: cyclic GMP-AMP (Standard); 3',3'-cGAMP (Standard)
Target:
Research Areas:
cGAMP (Standard) is the analytical standard of cGAMP (HY-12512). This product is intended for research and analytical applications. cGAMP (Cyclic GMP-AMP) functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators [3] .
Cat. No.: HY-112348
CAS No.: 92564-34-6
Target:
Research Areas:
HA-1004 hydrochloride is a selective inhibitor of PKA, which can inhibit lipolysis and induce vascular relaxation. HA-1004 hydrochloride is also a dual inhibitor of cyclic GMP-dependent protein kinase and cyclic AMP-dependent protein (Cyclic GMP-AMP Synthase), and is involved in smooth muscle, second messenger, cyclic AMP and cyclic GMP regulation mechanisms. HA-1004 hydrochloride an antagonist for calcium, that can be used as a vasodilator to inhibit the contraction of rabbit aortic strips, or to antagonize ERK and tyrosine hydroxylase (TH) phosphorylation in morphine abstinence rat models [3] .
Cat. No.: HY-W767865
Cat. No.: HY-W654000
Synonyms: Guanosine 3',5'-cyclic-13C,15N2 monophosphate
Cat. No.: HY-113469AR
CAS No.: 40732-48-7
Category:
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
