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2'-Deoxyguanosine-d

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Antibiotic (1) Apoptosis (3) Bacterial (3) Biochemical Assay Reagents (4) CMV (3) COX (1) Dengue Virus (2) DNA/RNA Synthesis (20) Drug Derivative (3) Endogenous Metabolite (23) Fluorescent Dye (2) Glutathione Peroxidase (1) HIV (1) HSV (1) Isotope-Labeled Compounds (26) Nucleoside Antimetabolite/Analog (32) Phosphoramidites (2) Reference Standards (4) Reverse Transcriptase (1) Somatostatin Receptor (1) Telomerase (1) TGF-β Receptor (1)
By Research Areas:	Cancer (32) Cardiovascular Disease (2) Endocrinology (1) Infection (14) Inflammation/Immunology (6) Metabolic Disease (14) Neurological Disease (1)
Click Chemistry:	Azide (2)
Oligonucleotides:	Guanine Nucleotide (1) Guanosine (16) Nucleotide Analogs (8) Nucleoside Analogs (19) Phosphoramidites (2) Guanine (2)

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Isotope-Labeled Compounds

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17365

Octreotide acetate 15+ Cited Publications SMS 201-995 acetate	Somatostatin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.

HY-17563

2'-Deoxyguanosine Maximum Cited Publications 6 Publications Verification Deoxyguanosine; Guanine deoxyriboside	Endogenous Metabolite	Cancer
2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells .

HY-18762

6-Thio-2'-Deoxyguanosine 2 Publications Verification 6-thio-dG; β-TGdR	DNA/RNA Synthesis	Cancer
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase.

HY-W011540

8-Hydroxy-2'-deoxyguanosine Maximum Cited Publications 6 Publications Verification 8-Oxo-2-Deoxyguanosine	Endogenous Metabolite	Cancer
8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.

HY-W011540S

*8-Hydroxy-2'-deoxyguanosine-15N5*	Endogenous Metabolite	Cancer
8-Hydroxy-2'-deoxyguanosine- ¹⁵N₅ is the ¹⁵N labeled 8-Hydroxy-2'-deoxyguanosine . 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis .

HY-D0185

*2'-Deoxyguanosine* monohydrate** Maximum Cited Publications 6 Publications Verification	Endogenous Metabolite	Metabolic Disease
2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and 2'-deoxyribose, and it is one of the basic structural units of DNA. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which in turn may affect gene expression or induce cancer .

HY-W013159

*2'-Deoxyguanosine* 5'-monophosphate disodium** 1 Publications Verification 5′-dGMP disodium	Endogenous Metabolite Nucleoside Antimetabolite/Analog	Metabolic Disease
2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .

HY-N0097A

9-β-D-Arabinofuranosylguanine AraG	Drug Derivative	Cancer
9-β-D-Arabinofuranosylguanine is a Guanosine (HY-N0097) analog and shows high affinity for deoxyguanosine kinase (dGK) with a K_m of 8.0 μM. 9-β-D-Arabinofuranosylguanine can be used for the research of T-cell lymphoblastic disease .

HY-W010702

5'-O-DMT-N2-ibu-dG N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-Deoxyguanosine	Nucleoside Antimetabolite/Analog Phosphoramidites	Others
5'-O-DMT-N2-ibu-dG (N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine) is a protected 2'-deoxyguanosine derivative with 5'-O-(4,4'-dimethoxytriphenylmethyl) and N2-isobutyryl protecting groups, and serves as a building block in oligonucleotide synthesis .

HY-W008661

Deoxyguanosine triphosphate trisodium solution (100 mM) 1 Publications Verification dGTP trisodium solution (100 mM); 2'-Deoxyguanosine-5'-triphosphate trisodium solution (100 mM)	DNA/RNA Synthesis	Others
Deoxyguanosine triphosphate (dGTP) trisodium solution (100 mM) is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification .

HY-W011168

8-Bromo-2'-deoxyguanosine	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis	Inflammation/Immunology Cancer
8-Bromo-2'-deoxyguanosine is an inflammation-related DNA halogenated adduct and an early biomarker of inflammation-induced oxidative tissue damage. The formation of 8-Bromo-2'-deoxyguanosine precedes that of oxidative and nitrative products, and it can be generated via the MPO-H₂O₂-Cl ^--Br ^- system. 8-Bromo-2'-deoxyguanosine serves as the immunogen for preparing the monoclonal antibody mAb8B3, which can be used to detect early DNA modifications in preclinical models; its urinary level also increases significantly in inflammatory disease models. 8-Bromo-2'-deoxyguanosine can also be produced in the dermis of UV-B irradiated mice, and the extract of Coprinus comatus significantly reduces its level. 8-Bromo-2'-deoxyguanosine finds applications in studies related to inflammatory diseases, diabetes, hepatocellular carcinoma, and UV-B induced skin inflammation .

HY-138616

dGTP 2'-Deoxyguanosine-5'-triphosphate	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog	Inflammation/Immunology
dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the precursors for DNA synthesis, and serves as a direct substrate for DNA replication and repair. dGTP is prone to oxidative damage; under the action of reactive oxygen species and other factors, dGTP is oxidized to form 8-oxo-dGTP .

HY-W013330

3′-Deoxyguanosine Guanosine, 3'-deoxy-	Nucleoside Antimetabolite/Analog Drug Derivative	Metabolic Disease
3′-Deoxyguanosine (Guanosine, 3'-deoxy-) is a derivative of Guanosine (HY-N0097). 3′-Deoxyguanosine interacts with human purine nucleoside phosphorylase via hydrogen bonding with residues such as Glu201 and Asn243. 3′-Deoxyguanosine exhibits moderate displacement activity for [ ³H]-guanosine in rat meninges. 3′-Deoxyguanosine is useful for studying the mechanism of guanosine receptors and purine metabolism .

HY-151688

6-O-Propynyl-2'-deoxyguanosine	ADC Linker	Others
6-O-Propynyl-2'-deoxyguanosine is a click chemistry reagent containing an alkyne group. 6-O-Propynyl-2'-deoxyguanosine can be used for the research of various biochemical .

HY-112817

8-Oxo-dGTP 8-Oxo-Deoxyguanosine triphosphate	Apoptosis	Cardiovascular Disease Neurological Disease Cancer
8-Oxo-dGTP (8-Oxo-Deoxyguanosine triphosphate) is an oxidized guanine nucleotide formed by ROS-mediated oxidative modification of dGTP, and it also serves as a key substrate for 8-oxo-dGTP pyrophosphohydrolases (such as hMTH1 and E. coli MutT). 8-Oxo-dGTP acts as a DNA mutagen, inserts into nascent DNA and pairs with adenine and cytosine, inducing A:T to C:G transversion mutations. Furthermore, 8-Oxo-dGTP causes oxidative DNA base modification, strand breakage and S-phase arrest, and ultimately triggers AIF-mediated apoptosis and promotes spontaneous carcinogenesis in mth1-deficient mice. Accumulation of 8-Oxo-dGTP in cells induces genomic instability, but it exhibits a tumor-suppressive effect that reduces tumor incidence in mouse models instead. 8-Oxo-dGTP is widely used in studies related to spontaneous carcinogenesis, Parkinson's disease, Alzheimer's disease, heart failure and tumor mechanisms .

HY-17563S3

*2'-Deoxyguanosine-d13* Deoxyguanosine-d₁₃; Guanine deoxyriboside-d₁₃	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
2'-Deoxyguanosine-d₁₃ (Deoxyguanosine-d₁₃; Guanine deoxyriboside-d₁₃) is deuterium labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.

HY-17563S2

*2'-Deoxyguanosine-13C10* Deoxyguanosine-¹³C₁₀; Guanine deoxyriboside-¹³C₁₀	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
2'-Deoxyguanosine- ¹³C₁₀ (Deoxyguanosine- ¹³C₁₀; Guanine deoxyriboside- ¹³C₁₀) is ¹³C-labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.

HY-17563R

*2'-Deoxyguanosine* (Standard)** Deoxyguanosine (Standard); Guanine deoxyriboside (Standard)	Reference Standards Endogenous Metabolite	Cancer
2'-Deoxyguanosine (Standard) is the analytical standard of 2'-Deoxyguanosine. This product is intended for research and analytical applications. 2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells . In Vitro: 2'-Deoxyguanosine inhibits the clonal growth of HL-60 and K562 leukemia cells with IC₅₀ values of 50 and 80 μM, respectively .

HY-W016011

iBu-dG N2-Isobutyryl-2'-Deoxyguanosine	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis	Cancer
iBu-dG (N2-Isobutyryl-2'-deoxyguanosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides .

HY-138616S3

dGTP-13C10 dilithium 2'-Deoxyguanosine-5'-triphosphate-13C10 dilithium	Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog	Infection Cancer
dGTP- ¹³C₁₀ (2'-Deoxyguanosine-5'-triphosphate- ¹³C₁₀) dilithium is ¹³C-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

HY-148169

2'-Deoxy-L-guanosine	Nucleoside Antimetabolite/Analog	Infection
2'-Deoxy-L-guanosine selectively inhibits D-Thymidine phosphorylation catalyzed by HSV 1 thymidine kinase. 2'-Deoxy-L-guanosine is the L-configuration of 2'-Deoxyguanosine (HY-17563) .

HY-W008661A

Deoxyguanosine triphosphate trisodium,100 mM Solution,PCR Grade dGTP trisodium,100 mM Solution,PCR Grade; 2'-Deoxyguanosine-5'-triphosphate trisodium,100 mM Solution,PCR Grade	DNA/RNA Synthesis	Others
Deoxyguanosine triphosphate (dGTP) trisodium,100 mM Solution,PCR Grade is one of the raw materials used by DNA polymerases to synthesize long DNA strands during DNA replication. Deoxyguanosine triphosphate trisodium,100 mM Solution,PCR Grade is used in polymerase chain reaction (PCR) for DNA amplification. This product is supplied in the form of an aqueous solution .

HY-131605B

Ganciclovir triphosphate disodium GCV-TP disodium	CMV DNA/RNA Synthesis	Infection Cancer
Ganciclovir triphosphate (GCV-TP) disodium is a synthetic 2'-deoxyguanosine analog with activity in inhibiting human cytomegalovirus (CMV) replication. Ganciclovir triphosphate disodium is effective against CMV infection by binding to viral DNA polymerase and interfering with viral DNA synthesis. Ganciclovir triphosphate disodium has an IC₅₀ of 0.01 μM against CMV strains from humans, monkeys, mice, and guinea pigs. Ganciclovir triphosphate disodium has also been used in gene-directed enzyme prodrug inhibition for cancer inhibition .

HY-13637S

Ganciclovir-d5 BW 759-d₅; 2'-Nor-2'-Deoxyguanosine-d₅	Isotope-Labeled Compounds CMV HSV Antibiotic Nucleoside Antimetabolite/Analog	Infection
Ganciclovir-d₅ is the deuterium labeled Ganciclovir. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC₅₀ of 5.2 μM for feline herpesvirus type-1 (FHV-1) .

HY-142028A

Acyclovir triphosphate sodium (100 mM) AcycloGTP sodium (100 mM)	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog HIV Reverse Transcriptase	Infection
Acyclovir triphosphate (Synonyms: AcycloGTP) sodium is a Acyclovir (HY-17422) derivative that competitively inhibits viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate (dGTP). Acyclovir triphosphate (sodium) (100 mM) is an inhibitor of HIV-1 reverse transcriptase. Acyclovir triphosphate (sodium) (100 mM) causes termination of viral DNA synthesis .

HY-N12851

4-OHE (E)-4-Oxo-2-hexenal	Bacterial Apoptosis	Infection
4-OHE ((E)-4-Oxo-2-hexenal) is a mutagen formed by omega-3 lipid peroxidation. 4-OHE reacts with deoxyguanosine, deoxycytidine and 5-methyldeoxycytidine to form covalent adducts. 4-OHE induces apoptosis and exhibits genotoxicity. 4-OHE inhibits the growth of Gram-positive and Gram-negative bacteria, which correlates with its electrophilic reactivity towards nucleophilic biomolecules. 4-OHE is a chemical defense component of Dolycoris baccarum (sloe bug), and acts as a deterrent and toxin against insect predators .

HY-W048492

7-Iodo-7-deaza-2'-deoxyguanosine 7-Deaza-7-Iodo-2'-Deoxyguanosine	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog	Others
7-Iodo-7-deaza-2'-deoxyguanosine (7-Deaza-7-Iodo-2'-deoxyguanosine) is a modified deoxyguanosine nucleoside. 7-Iodo-7-deaza-2'-deoxyguanosine is used in DNA synthesis and sequencing reactions .

HY-W011549

2'-Amino-2'-deoxyguanosine	Bacterial	Infection
2'-Amino-2'-deoxyguanosine is a nucleoside antibiotic. 2'-Amino-2'-deoxyguanosine exhibits lethal activity against certain strains of Escherichia coli, with its antibacterial effect reversible by guanosine and other purine nucleosides. 2'-Amino-2'-deoxyguanosine can be used for the study of bacterial infection .

HY-138616S4

dGTP-13C10,15N5 dilithium 2'-Deoxyguanosine-5'-triphosphate-13C10,15N5 dilithium	Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog	Infection Cancer
dGTP- ¹³C₁₀, ¹⁵N₅ (2'-Deoxyguanosine-5'-triphosphate- ¹³C₁₀, ¹⁵N₅) dilithium is ¹³C and ¹⁵N-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

HY-131605

Ganciclovir triphosphate GCV-TP	Endogenous Metabolite CMV DNA/RNA Synthesis	Infection Cancer
Ganciclovir triphosphate (GCV-TP) is a synthetic 2'-deoxyguanosine analog with activity in inhibiting human cytomegalovirus (CMV) replication. Ganciclovir triphosphate is effective against CMV infection by binding to viral DNA polymerase and interfering with viral DNA synthesis. Ganciclovir triphosphate has an IC₅₀ of 0.01 μM against CMV strains from humans, monkeys, mice, and guinea pigs. Ganciclovir triphosphate has also been used in gene-directed enzyme prodrug inhibition for cancer inhibition .

HY-131803

3'-Azido-3'-deoxyguanosine	Nucleoside Antimetabolite/Analog	Inflammation/Immunology
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model . 3'-Azido-3'-deoxyguanosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-D0185S4

*2'-Deoxyguanosine-13C10,15N5 monohydrate*	Endogenous Metabolite	Metabolic Disease
2'-Deoxyguanosine- ¹³C₁₀, ¹⁵N₅ (monohydrate) is the ¹³C and ¹⁵N labeled 2'-Deoxyguanosine monohydrate . 2'-Deoxyguanosine monohydrate is an endogenous metabolite.

HY-W013159S

*2'-Deoxyguanosine* 5'-monophosphate-13C10,15N5 disodium** 5′-dGMP-13C10,15N5 disodium	Isotope-Labeled Compounds Endogenous Metabolite Nucleoside Antimetabolite/Analog	Metabolic Disease
2'-Deoxyguanosine 5'-monophosphate- ¹³C₁₀, ¹⁵N₅ (dGMP- ¹³C₁₀, ¹⁵N₅) disodium is the ¹³C and ¹⁵N labeled 2'-Deoxyguanosine 5'-monophosphate disodium (HY-W013159). 2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .

HY-W011540R

*8-Hydroxy-2'-deoxyguanosine* (Standard)** 8-Oxo-2-Deoxyguanosine (Standard)	Reference Standards Endogenous Metabolite	Cancer
8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.

HY-154470

8-Aza-2’-deoxyguanosine	Nucleoside Antimetabolite/Analog	Cancer
8-Aza-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-P5443

Pyrrhocoricin	Bacterial	Others
Pyrrhocoricin is a biological active peptide. (Antimicrobial activity against Gram-negative bacteria)

HY-D0185S1

*2'-Deoxyguanosine-d* monohydrate**	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
2'-Deoxyguanosine-d (monohydrate) is the deuterium labeled 2'-Deoxyguanosine monohydrate. 2'-Deoxyguanosine monohydrate is an endogenous metabolite .

HY-D0185S

*2'-Deoxyguanosine-d2 monohydrate*	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
2'-Deoxyguanosine-d₂ (monohydrate) is the deuterium labeled 2'-Deoxyguanosine monohydrate. 2'-Deoxyguanosine monohydrate is an endogenous metabolite .

HY-W753153

*O-6-Methyl-2'-deoxyguanosine-d3*	Isotope-Labeled Compounds	Others
O-6-Methyl-2'-deoxyguanosine-d₃ is the deuterium labeled O-6-Methyl-2'-deoxyguanosine.

HY-17563S1

*2'-Deoxyguanosine-13C10,15N5* Deoxyguanosine-¹³C₁₀,¹⁵N₅; Guanine deoxyriboside-¹³C₁₀,¹⁵N₅	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
2'-Deoxyguanosine- ¹³C₁₀, ¹⁵N₅ (Deoxyguanosine- ¹³C₁₀, ¹⁵N₅; Guanine deoxyriboside- ¹³C₁₀, ¹⁵N₅) is a ¹³C- and ¹⁵N-labeled 2'-Deoxyguanosine (HY-17563).

HY-W250161

*7-Deaza-2′-deoxyguanosine* 5′-triphosphate** 7-Deaza-2'-dGTP	Telomerase	Cancer
7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, is a telomerase inhibitor (IC₅₀: 11 μM) .

HY-W721188

*2'-Deoxy-N-ethylguanosine-d6* N2-Ethyl-2'-Deoxyguanosine-d₆	Isotope-Labeled Compounds	Others
2'-Deoxy-N-ethylguanosine-d₆ (N2-Ethyl-2'-deoxyguanosine-d₆) is the deuterium labeled 2-(Ethylamino)-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one (HY-W013267).

HY-W767614

*O6-(2-Hydroxypropyl)-2'-deoxyguanosine-d3*	Isotope-Labeled Compounds	Others
O6-(2-Hydroxypropyl)-2'-deoxyguanosine-d₃ is the deuterium labeled O6-(2-Hydroxypropyl)-2'-deoxyguanosine.

HY-17563S4

*2'-Deoxyguanosine-15N5* Deoxyguanosine-¹⁵N₅; Guanine deoxyriboside-¹⁵N₅	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
2'-Deoxyguanosine- ¹⁵N₅ (Deoxyguanosine- ¹⁵N₅; Guanine deoxyriboside- ¹⁵N₅) is ¹⁵N labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.

HY-17563S

*2'-Deoxyguanosine-13C,15N2* Deoxyguanosine-¹³C,¹⁵N₂; Guanine deoxyriboside-¹³C,¹⁵N₂	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
2'-Deoxyguanosine- ¹³C, ¹⁵N₂ (Deoxyguanosine- ¹³C, ¹⁵N₂; Guanine deoxyriboside- ¹³C, ¹⁵N₂) is the ¹³C- and ¹⁵N-labeled labeled 2'-Deoxyguanosine (HY-17563). 2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells .

HY-W338294S2

*2'-Deoxyguanosine-13C monohydrate* Deoxyguanosine-13C monohydrate; Guanine deoxyriboside-13C monohydrate	Isotope-Labeled Compounds Endogenous Metabolite	Others
2'-Deoxyguanosine- ¹³C (monohydrate) Monohydrate is the ¹³C labeled 2'-Deoxyguanosine .

HY-W653916

*8-Hydroxy-2'-deoxyguanosine-13C,15N2* 8-Oxo-2-Deoxyguanosine-¹³C,¹⁵N₂	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
8-Hydroxy-2'-deoxyguanosine- ¹³C, ¹⁵N₂ is ¹³C and ¹⁵N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis .

HY-D0185R

*2'-Deoxyguanosine* monohydrate (Standard)**	Endogenous Metabolite Reference Standards	Metabolic Disease
2'-Deoxyguanosine monohydrate (Standard) is the analytical standard of 2'-Deoxyguanosine monohydrate. This product is intended for research and analytical applications. 2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and deoxyribose, and is one of the basic building blocks of DNA. In the oxidation reaction mediated by singlet oxygen 1O2, the guanine base of 2'-Deoxyguanosine is easily oxidized to generate two major products, 4,8-dihydro-4-hydroxy-8-oxodG and 7,8-dihydro-8-oxodG. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which may affect gene expression or induce cancer .

HY-W768213

*2'-Deoxyguanosine* monohydrate-13C5**	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
2'-Deoxyguanosine monohydrate- ¹³C₅ is the ¹³C-labeled 2'-Deoxyguanosine monohydrate (HY-D0185). 2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and deoxyribose, and is one of the basic building blocks of DNA. In the oxidation reaction mediated by singlet oxygen 1O2, the guanine base of 2'-Deoxyguanosine is easily oxidized to generate two major products, 4,8-dihydro-4-hydroxy-8-oxodG and 7,8-dihydro-8-oxodG. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which may affect gene expression or induce cancer .

HY-W393970S1

*2′-Deoxyguanosine* 5′-monophosphate-d12 dilithium** 5'-Deoxyguanylic acid-d12 dilithium	Isotope-Labeled Compounds	Others
2′-Deoxyguanosine 5′-monophosphate-d₁₂ (5'-Deoxyguanylic acid-d₁₂) dilithium is deuterium labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).

Cat. No.	Product Name	Type

HY-D3310

Fluorescein-12-dGTP

Fluorescent Dyes

Fluorescein-12-dGTP is a fluorescein-labeled deoxyguanosine triphosphate. Fluorescein-12-dGTP incorporates into complementary allele-specific primers at SNP sites, enabling FRET with cationic conjugated polymer PFP via DNA-PFP electrostatic interactions. Fluorescein-12-dGTP incorporates into G-allele-specific primers for homozygous G/G SNP genotypes to enable genotype discrimination. Fluorescein-12-dGTP serves as a fluorescently labeled nucleotide for homogeneous solution-based SNP and FRET genotyping assays (Ex/Em = 498/517 nm) .

Cat. No.	Product Name	Type

HY-W008661

Deoxyguanosine triphosphate trisodium solution (100 mM) 1 Publications Verification dGTP trisodium solution (100 mM); 2'-Deoxyguanosine-5'-triphosphate trisodium solution (100 mM)	Biochemical Assay Reagents
Deoxyguanosine triphosphate (dGTP) trisodium solution (100 mM) is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification .

HY-W008661A

Deoxyguanosine triphosphate trisodium,100 mM Solution,PCR Grade dGTP trisodium,100 mM Solution,PCR Grade; 2'-Deoxyguanosine-5'-triphosphate trisodium,100 mM Solution,PCR Grade	Biochemical Assay Reagents
Deoxyguanosine triphosphate (dGTP) trisodium,100 mM Solution,PCR Grade is one of the raw materials used by DNA polymerases to synthesize long DNA strands during DNA replication. Deoxyguanosine triphosphate trisodium,100 mM Solution,PCR Grade is used in polymerase chain reaction (PCR) for DNA amplification. This product is supplied in the form of an aqueous solution .

HY-142028A

Acyclovir triphosphate sodium (100 mM) AcycloGTP sodium (100 mM)	Biochemical Assay Reagents
Acyclovir triphosphate (Synonyms: AcycloGTP) sodium is a Acyclovir (HY-17422) derivative that competitively inhibits viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate (dGTP). Acyclovir triphosphate (sodium) (100 mM) is an inhibitor of HIV-1 reverse transcriptase. Acyclovir triphosphate (sodium) (100 mM) causes termination of viral DNA synthesis .

HY-W048492

7-Iodo-7-deaza-2'-deoxyguanosine 7-Deaza-7-Iodo-2'-Deoxyguanosine	Biochemical Assay Reagents
7-Iodo-7-deaza-2'-deoxyguanosine (7-Deaza-7-Iodo-2'-deoxyguanosine) is a modified deoxyguanosine nucleoside. 7-Iodo-7-deaza-2'-deoxyguanosine is used in DNA synthesis and sequencing reactions .

HY-W011549

2'-Amino-2'-deoxyguanosine	Biochemical Assay Reagents
2'-Amino-2'-deoxyguanosine is a nucleoside antibiotic. 2'-Amino-2'-deoxyguanosine exhibits lethal activity against certain strains of Escherichia coli, with its antibacterial effect reversible by guanosine and other purine nucleosides. 2'-Amino-2'-deoxyguanosine can be used for the study of bacterial infection .

HY-132144

7-Deaza-7-propargylamino-dGTP	Biochemical Assay Reagents
7-Deaza-7-propargylamino-dGTP is an analog of deoxyguanosine triphosphate (dGTP) that can be used for gene sequencing .

HY-132140

7-Deaza-7-propargylamino-3'-azidomethyl-dGTP	Biochemical Assay Reagents
7-Deaza-7-propargylamino-3'-azidomethyl-dGTP is an analog of deoxyguanosine triphosphate (dGTP) that widely used in the next generation sequencing (NGS) .

HY-132144A

7-Deaza-7-propargylamino-dGTP sodium	Biochemical Assay Reagents
7-Deaza-7-propargylamino-dGTP sodium is the sodium salt form of 7-Deaza-7-propargylamino-dGTP (HY-132144). 7-Deaza-7-propargylamino-dGTP sodium is an analog of deoxyguanosine triphosphate dGTP (HY-W008661) and can be used for gene sequencing .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W011540

8-Hydroxy-2'-deoxyguanosine Maximum Cited Publications 6 Publications Verification 8-Oxo-2-Deoxyguanosine	Structural Classification Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite
8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.

HY-W013159

*2'-Deoxyguanosine* 5'-monophosphate disodium** 1 Publications Verification 5′-dGMP disodium	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Nucleoside Antimetabolite/Analog
2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .

HY-138616

dGTP 2'-Deoxyguanosine-5'-triphosphate	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog
dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the precursors for DNA synthesis, and serves as a direct substrate for DNA replication and repair. dGTP is prone to oxidative damage; under the action of reactive oxygen species and other factors, dGTP is oxidized to form 8-oxo-dGTP .

HY-112817

8-Oxo-dGTP 8-Oxo-Deoxyguanosine triphosphate	Microorganisms Source Classification	Apoptosis
8-Oxo-dGTP (8-Oxo-Deoxyguanosine triphosphate) is an oxidized guanine nucleotide formed by ROS-mediated oxidative modification of dGTP, and it also serves as a key substrate for 8-oxo-dGTP pyrophosphohydrolases (such as hMTH1 and E. coli MutT). 8-Oxo-dGTP acts as a DNA mutagen, inserts into nascent DNA and pairs with adenine and cytosine, inducing A:T to C:G transversion mutations. Furthermore, 8-Oxo-dGTP causes oxidative DNA base modification, strand breakage and S-phase arrest, and ultimately triggers AIF-mediated apoptosis and promotes spontaneous carcinogenesis in mth1-deficient mice. Accumulation of 8-Oxo-dGTP in cells induces genomic instability, but it exhibits a tumor-suppressive effect that reduces tumor incidence in mouse models instead. 8-Oxo-dGTP is widely used in studies related to spontaneous carcinogenesis, Parkinson's disease, Alzheimer's disease, heart failure and tumor mechanisms .

HY-17563R

*2'-Deoxyguanosine* (Standard)** Deoxyguanosine (Standard); Guanine deoxyriboside (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Disease markers Endocrine diseases Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
2'-Deoxyguanosine (Standard) is the analytical standard of 2'-Deoxyguanosine. This product is intended for research and analytical applications. 2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells . In Vitro: 2'-Deoxyguanosine inhibits the clonal growth of HL-60 and K562 leukemia cells with IC₅₀ values of 50 and 80 μM, respectively .

HY-N12851

4-OHE (E)-4-Oxo-2-hexenal	Structural Classification Animals Ketones, Aldehydes, Acids Source Classification	Bacterial Apoptosis
4-OHE ((E)-4-Oxo-2-hexenal) is a mutagen formed by omega-3 lipid peroxidation. 4-OHE reacts with deoxyguanosine, deoxycytidine and 5-methyldeoxycytidine to form covalent adducts. 4-OHE induces apoptosis and exhibits genotoxicity. 4-OHE inhibits the growth of Gram-positive and Gram-negative bacteria, which correlates with its electrophilic reactivity towards nucleophilic biomolecules. 4-OHE is a chemical defense component of Dolycoris baccarum (sloe bug), and acts as a deterrent and toxin against insect predators .

HY-W011540R

*8-Hydroxy-2'-deoxyguanosine* (Standard)** 8-Oxo-2-Deoxyguanosine (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.

HY-D0185R

*2'-Deoxyguanosine* monohydrate (Standard)**	Structural Classification Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
2'-Deoxyguanosine monohydrate (Standard) is the analytical standard of 2'-Deoxyguanosine monohydrate. This product is intended for research and analytical applications. 2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and deoxyribose, and is one of the basic building blocks of DNA. In the oxidation reaction mediated by singlet oxygen 1O2, the guanine base of 2'-Deoxyguanosine is easily oxidized to generate two major products, 4,8-dihydro-4-hydroxy-8-oxodG and 7,8-dihydro-8-oxodG. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which may affect gene expression or induce cancer .

HY-W013159R

*2'-Deoxyguanosine* 5'-monophosphate disodium (Standard)** 5′-dGMP disodium (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards Nucleoside Antimetabolite/Analog
2'-Deoxyguanosine 5'-monophosphate (disodium) (Standard) is the analytical standard of 2'-Deoxyguanosine 5'-monophosphate (disodium) (HY-W013159). This product is intended for research and analytical applications. 2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .

Cat. No.	Product Name	Chemical Structure

HY-W011540S

*8-Hydroxy-2'-deoxyguanosine-15N5*
8-Hydroxy-2'-deoxyguanosine- ¹⁵N₅ is the ¹⁵N labeled 8-Hydroxy-2'-deoxyguanosine . 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis .

HY-17563S3

*2'-Deoxyguanosine-d13*
2'-Deoxyguanosine-d₁₃ (Deoxyguanosine-d₁₃; Guanine deoxyriboside-d₁₃) is deuterium labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.

HY-17563S2

*2'-Deoxyguanosine-13C10*
2'-Deoxyguanosine- ¹³C₁₀ (Deoxyguanosine- ¹³C₁₀; Guanine deoxyriboside- ¹³C₁₀) is ¹³C-labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.

HY-138616S3

dGTP-13C10 dilithium
dGTP- ¹³C₁₀ (2'-Deoxyguanosine-5'-triphosphate- ¹³C₁₀) dilithium is ¹³C-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

HY-13637S

Ganciclovir-d5

Ganciclovir-d₅ is the deuterium labeled Ganciclovir. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC₅₀ of 5.2 μM for feline herpesvirus type-1 (FHV-1) .

HY-138616S4

dGTP-13C10,15N5 dilithium

dGTP- ¹³C₁₀, ¹⁵N₅ (2'-Deoxyguanosine-5'-triphosphate- ¹³C₁₀, ¹⁵N₅) dilithium is ¹³C and ¹⁵N-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

HY-D0185S4

*2'-Deoxyguanosine-13C10,15N5 monohydrate*
2'-Deoxyguanosine- ¹³C₁₀, ¹⁵N₅ (monohydrate) is the ¹³C and ¹⁵N labeled 2'-Deoxyguanosine monohydrate . 2'-Deoxyguanosine monohydrate is an endogenous metabolite.

HY-W013159S

2'-Deoxyguanosine 5'-monophosphate-13C10,15N5 disodium

2'-Deoxyguanosine 5'-monophosphate- ¹³C₁₀, ¹⁵N₅ (dGMP- ¹³C₁₀, ¹⁵N₅) disodium is the ¹³C and ¹⁵N labeled 2'-Deoxyguanosine 5'-monophosphate disodium (HY-W013159). 2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .

HY-D0185S1

*2'-Deoxyguanosine-d* monohydrate**
2'-Deoxyguanosine-d (monohydrate) is the deuterium labeled 2'-Deoxyguanosine monohydrate. 2'-Deoxyguanosine monohydrate is an endogenous metabolite .

HY-D0185S

*2'-Deoxyguanosine-d2 monohydrate*
2'-Deoxyguanosine-d₂ (monohydrate) is the deuterium labeled 2'-Deoxyguanosine monohydrate. 2'-Deoxyguanosine monohydrate is an endogenous metabolite .

HY-W753153

*O-6-Methyl-2'-deoxyguanosine-d3*
O-6-Methyl-2'-deoxyguanosine-d₃ is the deuterium labeled O-6-Methyl-2'-deoxyguanosine.

HY-17563S1

*2'-Deoxyguanosine-13C10,15N5*
2'-Deoxyguanosine- ¹³C₁₀, ¹⁵N₅ (Deoxyguanosine- ¹³C₁₀, ¹⁵N₅; Guanine deoxyriboside- ¹³C₁₀, ¹⁵N₅) is a ¹³C- and ¹⁵N-labeled 2'-Deoxyguanosine (HY-17563).

HY-W721188

*2'-Deoxy-N-ethylguanosine-d6*
2'-Deoxy-N-ethylguanosine-d₆ (N2-Ethyl-2'-deoxyguanosine-d₆) is the deuterium labeled 2-(Ethylamino)-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one (HY-W013267).

HY-W767614

*O6-(2-Hydroxypropyl)-2'-deoxyguanosine-d3*
O6-(2-Hydroxypropyl)-2'-deoxyguanosine-d₃ is the deuterium labeled O6-(2-Hydroxypropyl)-2'-deoxyguanosine.

HY-17563S4

*2'-Deoxyguanosine-15N5*
2'-Deoxyguanosine- ¹⁵N₅ (Deoxyguanosine- ¹⁵N₅; Guanine deoxyriboside- ¹⁵N₅) is ¹⁵N labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.

HY-17563S

2'-Deoxyguanosine-13C,15N2

2'-Deoxyguanosine- ¹³C, ¹⁵N₂ (Deoxyguanosine- ¹³C, ¹⁵N₂; Guanine deoxyriboside- ¹³C, ¹⁵N₂) is the ¹³C- and ¹⁵N-labeled labeled 2'-Deoxyguanosine (HY-17563). 2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells .

HY-W338294S2

*2'-Deoxyguanosine-13C monohydrate*
2'-Deoxyguanosine- ¹³C (monohydrate) Monohydrate is the ¹³C labeled 2'-Deoxyguanosine .

HY-W653916

*8-Hydroxy-2'-deoxyguanosine-13C,15N2*
8-Hydroxy-2'-deoxyguanosine- ¹³C, ¹⁵N₂ is ¹³C and ¹⁵N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis .

HY-W768213

2'-Deoxyguanosine monohydrate-13C5

2'-Deoxyguanosine monohydrate- ¹³C₅ is the ¹³C-labeled 2'-Deoxyguanosine monohydrate (HY-D0185). 2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and deoxyribose, and is one of the basic building blocks of DNA. In the oxidation reaction mediated by singlet oxygen 1O2, the guanine base of 2'-Deoxyguanosine is easily oxidized to generate two major products, 4,8-dihydro-4-hydroxy-8-oxodG and 7,8-dihydro-8-oxodG. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which may affect gene expression or induce cancer .

HY-W393970S1

*2′-Deoxyguanosine* 5′-monophosphate-d12 dilithium**
2′-Deoxyguanosine 5′-monophosphate-d₁₂ (5'-Deoxyguanylic acid-d₁₂) dilithium is deuterium labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).

HY-W393970S4

*2′-Deoxyguanosine* 5′-monophosphate-15N5 dilithium**
2′-Deoxyguanosine 5′-monophosphate- ¹⁵N₅ (5'-Deoxyguanylic acid- ¹⁵N₅) dilithium is ¹⁵N labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).

HY-W393970S2

*2′-Deoxyguanosine* 5′-monophosphate-13C10 dilithium**
2′-Deoxyguanosine 5′-monophosphate- ¹³C₁₀ (5'-Deoxyguanylic acid- ¹³C₁₀) dilithium is ¹³C-labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).

HY-W767399

8-Bromo-2'-deoxyguanosine-13C,15N2

8-Bromo-2'-deoxyguanosine- ¹³C, ¹⁵N2 is the ¹³C- and ¹⁵N-labeled 8-Bromo-2'-deoxyguanosine (HY-W011168). 8-Bromo-2'-deoxyguanosine is an inflammation-related DNA halogenated adduct and an early biomarker of inflammation-induced oxidative tissue damage. The formation of 8-Bromo-2'-deoxyguanosine precedes that of oxidative and nitrative products, and it can be generated via the MPO-H₂O₂-Cl ^--Br ^- system. 8-Bromo-2'-deoxyguanosine serves as the immunogen for preparing the monoclonal antibody mAb8B3, which can be used to detect early DNA modifications in preclinical models; its urinary level also increases significantly in inflammatory disease models. 8-Bromo-2'-deoxyguanosine can also be produced in the dermis of UV-B irradiated mice, and the extract of Coprinus comatus significantly reduces its level. 8-Bromo-2'-deoxyguanosine finds applications in studies related to inflammatory diseases, diabetes, hepatocellular carcinoma, and UV-B induced skin inflammation .

HY-W393970S3

*2′-Deoxyguanosine* 5′-monophosphate-13C10,15N5 dilithium**
2′-Deoxyguanosine 5′-monophosphate- ¹³C₁₀, ¹⁵N₅ (5'-Deoxyguanylic acid- ¹³C₁₀, ¹⁵N₅) dilithium is ¹³C and ¹⁵N-labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).

HY-W393970S

*2′-Deoxyguanosine* 5′-monophosphate-15N5,d12 dilithium**
2′-Deoxyguanosine 5′-monophosphate- ¹⁵N₅,d₁₂ (5'-Deoxyguanylic acid- ¹⁵N₅,d₁₂) dilithium is deuterium and ¹⁵N labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).

HY-138616S1

dGTP-d14 dilithium
dGTP-d₁₄ (2'-Deoxyguanosine-5'-triphosphate-d₁₄) dilithium is deuterium labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

HY-138616S

dGTP-15N5 dilithium
dGTP- ¹⁵N₅ (2'-Deoxyguanosine-5'-triphosphate- ¹⁵N₅) dilithium is ¹⁵N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

HY-138616S2

dGTP-15N5,d14 dilithium

dGTP- ¹⁵N₅,d₁₄ (2'-Deoxyguanosine-5'-triphosphate- ¹⁵N₅,d₁₄) dilithium is deuterium and ¹⁵N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

Cat. No.	Product Name		Classification

HY-131803

3'-Azido-3'-deoxyguanosine		Azide
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model . 3'-Azido-3'-deoxyguanosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-132140A

7-Deaza-7-propargylamino-3'-azidomethyl-dGTP triethylamine		Azide
7-Deaza-7-propargylamino-3'-azidomethyl-dGTP triethylamine is an analog of deoxyguanosine triphosphate (dGTP) that widely used in the next generation sequencing (NGS) .

Cat. No.	Product Name		Classification

HY-17563

2'-Deoxyguanosine Maximum Cited Publications 6 Publications Verification Deoxyguanosine; Guanine deoxyriboside		Nucleoside Analogs Guanosine
2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells .

HY-18762

6-Thio-2'-Deoxyguanosine 2 Publications Verification 6-thio-dG; β-TGdR		Nucleoside Analogs Guanosine
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase.

HY-W011540

8-Hydroxy-2'-deoxyguanosine Maximum Cited Publications 6 Publications Verification 8-Oxo-2-Deoxyguanosine		Nucleoside Analogs Guanosine
8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.

HY-D0185

*2'-Deoxyguanosine* monohydrate** Maximum Cited Publications 6 Publications Verification		Nucleoside Analogs Guanosine
2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and 2'-deoxyribose, and it is one of the basic structural units of DNA. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which in turn may affect gene expression or induce cancer .

HY-W013159

*2'-Deoxyguanosine* 5'-monophosphate disodium** 1 Publications Verification 5′-dGMP disodium		Nucleotide Analogs
2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .

HY-W010702

5'-O-DMT-N2-ibu-dG N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-Deoxyguanosine		Phosphoramidites Guanine
5'-O-DMT-N2-ibu-dG (N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine) is a protected 2'-deoxyguanosine derivative with 5'-O-(4,4'-dimethoxytriphenylmethyl) and N2-isobutyryl protecting groups, and serves as a building block in oligonucleotide synthesis .

HY-W008661

Deoxyguanosine triphosphate trisodium solution (100 mM) 1 Publications Verification dGTP trisodium solution (100 mM); 2'-Deoxyguanosine-5'-triphosphate trisodium solution (100 mM)		Nucleotide Analogs
Deoxyguanosine triphosphate (dGTP) trisodium solution (100 mM) is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification .

HY-W011168

8-Bromo-2'-deoxyguanosine		Nucleoside Analogs Guanosine
8-Bromo-2'-deoxyguanosine is an inflammation-related DNA halogenated adduct and an early biomarker of inflammation-induced oxidative tissue damage. The formation of 8-Bromo-2'-deoxyguanosine precedes that of oxidative and nitrative products, and it can be generated via the MPO-H₂O₂-Cl ^--Br ^- system. 8-Bromo-2'-deoxyguanosine serves as the immunogen for preparing the monoclonal antibody mAb8B3, which can be used to detect early DNA modifications in preclinical models; its urinary level also increases significantly in inflammatory disease models. 8-Bromo-2'-deoxyguanosine can also be produced in the dermis of UV-B irradiated mice, and the extract of Coprinus comatus significantly reduces its level. 8-Bromo-2'-deoxyguanosine finds applications in studies related to inflammatory diseases, diabetes, hepatocellular carcinoma, and UV-B induced skin inflammation .

HY-138616

dGTP 2'-Deoxyguanosine-5'-triphosphate		Nucleotide Analogs
dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the precursors for DNA synthesis, and serves as a direct substrate for DNA replication and repair. dGTP is prone to oxidative damage; under the action of reactive oxygen species and other factors, dGTP is oxidized to form 8-oxo-dGTP .

HY-W013330

3′-Deoxyguanosine Guanosine, 3'-deoxy-		Nucleoside Analogs Guanosine
3′-Deoxyguanosine (Guanosine, 3'-deoxy-) is a derivative of Guanosine (HY-N0097). 3′-Deoxyguanosine interacts with human purine nucleoside phosphorylase via hydrogen bonding with residues such as Glu201 and Asn243. 3′-Deoxyguanosine exhibits moderate displacement activity for [ ³H]-guanosine in rat meninges. 3′-Deoxyguanosine is useful for studying the mechanism of guanosine receptors and purine metabolism .

HY-W016011

iBu-dG N2-Isobutyryl-2'-Deoxyguanosine		Nucleoside Analogs Guanosine
iBu-dG (N2-Isobutyryl-2'-deoxyguanosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides .

HY-148169

2'-Deoxy-L-guanosine		Nucleoside Analogs Guanosine
2'-Deoxy-L-guanosine selectively inhibits D-Thymidine phosphorylation catalyzed by HSV 1 thymidine kinase. 2'-Deoxy-L-guanosine is the L-configuration of 2'-Deoxyguanosine (HY-17563) .

HY-W048492

7-Iodo-7-deaza-2'-deoxyguanosine 7-Deaza-7-Iodo-2'-Deoxyguanosine		Nucleoside Analogs Guanosine
7-Iodo-7-deaza-2'-deoxyguanosine (7-Deaza-7-Iodo-2'-deoxyguanosine) is a modified deoxyguanosine nucleoside. 7-Iodo-7-deaza-2'-deoxyguanosine is used in DNA synthesis and sequencing reactions .

HY-154470

8-Aza-2’-deoxyguanosine		Nucleoside Analogs Guanosine
8-Aza-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152351

8-Bromo-3’-deoxyguanosine		Nucleoside Analogs Guanosine
8-Bromo-3’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152367

8-Hydroxy-3'-deoxyguanosine		Nucleoside Analogs Guanosine
8-Hydroxy-3’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154243

8-Methyl-2’-deoxyguanosine		Nucleoside Analogs Guanosine
8-Methyl-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152354

8-Benzyloxy-3’-deoxyguanosine		Nucleoside Analogs Guanosine
8-Benzyloxy-3’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W425099

*2'-Deoxyguanosine-(N-iBu)-3'-methyl-phosphoramidite*		Phosphoramidites Guanine
2'-Deoxyguanosine-(N-iBu)-3'-methyl-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-W098689

Dmf-dg 2'-Deoxy-N2-dimethylaminomethylene-guanosine		Nucleoside Analogs Guanosine
Dmf-dg (2'-Deoxy-N2-dimethylaminomethylene-guanosine) is a deoxyguanosine (dG) nucleoside protected by the dimethylaminomethylamidine (DMF) base and can be used for oligonucleotide synthesis .

HY-132140A

7-Deaza-7-propargylamino-3'-azidomethyl-dGTP triethylamine		Nucleotide Analogs
7-Deaza-7-propargylamino-3'-azidomethyl-dGTP triethylamine is an analog of deoxyguanosine triphosphate (dGTP) that widely used in the next generation sequencing (NGS) .

HY-154478

3’-O-Acetyl-N2-iso-Butyroyl-2’-deoxy-guanosine		Nucleoside Analogs Guanosine
3’-O-Acetyl-N2-iso-Butyroyl-2’-deoxy-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W749893

dGDP sodium 2'-Deoxyguanosine-5'-diphosphate sodium		Nucleoside Analogs Nucleotide Analogs
dGDP (2'-Deoxyguanosine-5'-diphosphate) sodium is a monomeric raw material that can be used for nucleic acid synthesis.

HY-W784575

dGTPαS 2'-Deoxyguanosine-5'-O-(α-thio)triphosphate		Nucleoside Analogs Nucleotide Analogs
dGTPαS (2'-Deoxyguanosine-5'-O-(α-thio)triphosphate) is a monomeric raw material that can be used for nucleic acid synthesis.

HY-W048518

7-Deaza-2'-dG 7-Deaza-2'-Deoxyguanosine		Nucleoside Analogs Nucleotide Analogs
7-Deaza-2'-dG (7-Deaza-2'-deoxyguanosine) is a monomeric raw material that can be used for nucleic acid synthesis.

HY-112817A

8-Oxo-dGTP trisodium solution (100 mM) 8-Oxo-Deoxyguanosine triphosphate trisodium		Nucleotide Analogs Guanine Nucleotide
8-Oxo-dGTP (8-Oxo-Deoxyguanosine triphosphate) trisodium solution (100mM) is an oxidized guanine nucleotide formed by ROS-mediated oxidative modification of dGTP, and it also serves as a key substrate for 8-oxo-dGTP pyrophosphohydrolases (such as hMTH1 and E. coli MutT). 8-Oxo-dGTP trisodium solution (100mM) acts as a DNA mutagen, inserts into nascent DNA and pairs with adenine and cytosine, inducing A:T to C:G transversion mutations. Furthermore, 8-Oxo-dGTP trisodium solution (100mM) causes oxidative DNA base modification, strand breakage and S-phase arrest, and ultimately triggers AIF-mediated apoptosis and promotes spontaneous carcinogenesis in mth1-deficient mice. Accumulation of 8-Oxo-dGTP trisodium solution (100mM) in cells induces genomic instability, but it exhibits a tumor-suppressive effect that reduces tumor incidence in mouse models instead. 8-Oxo-dGTP trisodium solution (100mM) is widely used in studies related to spontaneous carcinogenesis, Parkinson's disease, Alzheimer's disease, heart failure and tumor mechanisms .

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