84 Results for "

2'-Deoxyguanosine-d

" in MedChemExpress (MCE) Product Catalog:
Products (84)

84 Results for "2'-Deoxyguanosine-d" in MCE Product Catalog:

17
17 Publications Verification
Cat. No.: HY-17365
CAS No.: 79517-01-4
Synonyms: SMS 201-995 acetate
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.
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7
7 Cited Publications
Cat. No.: HY-W011540
CAS No.: 88847-89-6
Synonyms: 8-Oxo-2-Deoxyguanosine
8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.
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6
6 Cited Publications
Cat. No.: HY-17563
CAS No.: 961-07-9
Synonyms: Deoxyguanosine; Guanine deoxyriboside
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells .
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6
6 Cited Publications
Cat. No.: HY-D0185
CAS No.: 312693-72-4
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and 2'-deoxyribose, and it is one of the basic structural units of DNA. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which in turn may affect gene expression or induce cancer .
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2
2 Cited Publications
Cat. No.: HY-18762
CAS No.: 789-61-7
Synonyms: 6-thio-dG; β-TGdR
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase.
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1
1 Cited Publications
Cat. No.: HY-W013159
CAS No.: 33430-61-4
Synonyms: 5′-dGMP disodium
2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .
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1
1 Cited Publications
Cat. No.: HY-W008661
CAS No.: 93919-41-6
Synonyms: dGTP trisodium solution (100 mM); 2'-Deoxyguanosine-5'-triphosphate trisodium solution (100 mM)
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

Deoxyguanosine triphosphate (dGTP) trisodium solution (100 mM) is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification .
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1
1 Cited Publications
Cat. No.: HY-138616
CAS No.: 2564-35-4
Synonyms: 2'-Deoxyguanosine-5'-triphosphate
dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the precursors for DNA synthesis, and serves as a direct substrate for DNA replication and repair. dGTP is prone to oxidative damage; under the action of reactive oxygen species and other factors, dGTP is oxidized to form 8-oxo-dGTP .
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Cat. No.: HY-W011540S
CAS No.: 569649-11-2
8-Hydroxy-2'-deoxyguanosine- 15N5 is the 15N labeled 8-Hydroxy-2'-deoxyguanosine . 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis .
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Cat. No.: HY-N0097A
CAS No.: 38819-10-2
Synonyms: AraG
Target:  

Drug Derivative

Research Areas:  

Cancer

9-β-D-Arabinofuranosylguanine is a Guanosine (HY-N0097) analog and shows high affinity for deoxyguanosine kinase (dGK) with a Km of 8.0 μM. 9-β-D-Arabinofuranosylguanine can be used for the research of T-cell lymphoblastic disease .
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Cat. No.: HY-W010702
CAS No.: 68892-41-1
Synonyms: N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-Deoxyguanosine
Research Areas:  

Others

5'-O-DMT-N2-ibu-dG (N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine) is a protected 2'-deoxyguanosine derivative with 5'-O-(4,4'-dimethoxytriphenylmethyl) and N2-isobutyryl protecting groups, and serves as a building block in oligonucleotide synthesis .
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Cat. No.: HY-W011168
CAS No.: 13389-03-2
8-Bromo-2'-deoxyguanosine is an inflammation-related DNA halogenated adduct and an early biomarker of inflammation-induced oxidative tissue damage. The formation of 8-Bromo-2'-deoxyguanosine precedes that of oxidative and nitrative products, and it can be generated via the MPO-H2O2-Cl --Br - system. 8-Bromo-2'-deoxyguanosine serves as the immunogen for preparing the monoclonal antibody mAb8B3, which can be used to detect early DNA modifications in preclinical models; its urinary level also increases significantly in inflammatory disease models. 8-Bromo-2'-deoxyguanosine can also be produced in the dermis of UV-B irradiated mice, and the extract of Coprinus comatus significantly reduces its level. 8-Bromo-2'-deoxyguanosine finds applications in studies related to inflammatory diseases, diabetes, hepatocellular carcinoma, and UV-B induced skin inflammation .
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Cat. No.: HY-W013330
CAS No.: 3608-58-0
Synonyms: Guanosine, 3'-deoxy-
3′-Deoxyguanosine (Guanosine, 3'-deoxy-) is a derivative of Guanosine (HY-N0097). 3′-Deoxyguanosine interacts with human purine nucleoside phosphorylase via hydrogen bonding with residues such as Glu201 and Asn243. 3′-Deoxyguanosine exhibits moderate displacement activity for [ 3H]-guanosine in rat meninges. 3′-Deoxyguanosine is useful for studying the mechanism of guanosine receptors and purine metabolism .
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Cat. No.: HY-151688
CAS No.: 1640051-47-3
Purity:  99.30%
Target:  

ADC Linkers

Research Areas:  

Others

6-O-Propynyl-2'-deoxyguanosine is a click chemistry reagent containing an alkyne group. 6-O-Propynyl-2'-deoxyguanosine can be used for the research of various biochemical .
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Cat. No.: HY-112817
CAS No.: 139307-94-1
Synonyms: 8-Oxo-Deoxyguanosine triphosphate
8-Oxo-dGTP (8-Oxo-Deoxyguanosine triphosphate) is an oxidized guanine nucleotide formed by ROS-mediated oxidative modification of dGTP, and it also serves as a key substrate for 8-oxo-dGTP pyrophosphohydrolases (such as hMTH1 and E. coli MutT). 8-Oxo-dGTP acts as a DNA mutagen, inserts into nascent DNA and pairs with adenine and cytosine, inducing A:T to C:G transversion mutations. Furthermore, 8-Oxo-dGTP causes oxidative DNA base modification, strand breakage and S-phase arrest, and ultimately triggers AIF-mediated apoptosis and promotes spontaneous carcinogenesis in mth1-deficient mice. Accumulation of 8-Oxo-dGTP in cells induces genomic instability, but it exhibits a tumor-suppressive effect that reduces tumor incidence in mouse models instead. 8-Oxo-dGTP is widely used in studies related to spontaneous carcinogenesis, Parkinson's disease, Alzheimer's disease, heart failure and tumor mechanisms .
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Cat. No.: HY-17563S3
Synonyms: Deoxyguanosine-d13; Guanine deoxyriboside-d13
2'-Deoxyguanosine-d13 (Deoxyguanosine-d13; Guanine deoxyriboside-d13) is deuterium labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.
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Cat. No.: HY-17563S2
CAS No.: 1245539-86-9
Synonyms: Deoxyguanosine-13C10; Guanine deoxyriboside-13C10
2'-Deoxyguanosine- 13C10 (Deoxyguanosine- 13C10; Guanine deoxyriboside- 13C10) is 13C-labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.
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Cat. No.: HY-17563R
CAS No.: 961-07-9
Synonyms: Deoxyguanosine (Standard); Guanine deoxyriboside (Standard)
2'-Deoxyguanosine (Standard) is the analytical standard of 2'-Deoxyguanosine. This product is intended for research and analytical applications. 2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells . In Vitro: 2'-Deoxyguanosine inhibits the clonal growth of HL-60 and K562 leukemia cells with IC50 values of 50 and 80 μM, respectively .
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Cat. No.: HY-W016011
CAS No.: 68892-42-2
Synonyms: N2-Isobutyryl-2'-Deoxyguanosine
iBu-dG (N2-Isobutyryl-2'-deoxyguanosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides .
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Cat. No.: HY-138616S3
Purity:  98.8%
Synonyms: 2'-Deoxyguanosine-5'-triphosphate-13C10 dilithium
dGTP- 13C10 (2'-Deoxyguanosine-5'-triphosphate- 13C10) dilithium is 13C-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
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