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Results for "

3 LL

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amine N-methyltransferase (1) Angiotensin Receptor (1) Antibiotic (12) Apoptosis (5) ATM/ATR (1) Autophagy (1) Bacterial (39) Beclin1 (1) Biochemical Assay Reagents (1) c-Myc (1) CaMK (1) Carbonic Anhydrase (2) CDK (4) COX (1) Dihydrofolate reductase (DHFR) (1) DNA/RNA Synthesis (1) Drug Derivative (2) Drug Metabolite (1) Early 2 Factor (E2F) (1) Endogenous Metabolite (5) Enterovirus (3) Fluorescent Dye (3) Formyl Peptide Receptor (FPR) (2) Fungal (1) Glutathione Peroxidase (1) Histone Methyltransferase (1) HIV (1) HSV (1) IFNAR (1) Influenza Virus (1) Interleukin Related (3) Isotope-Labeled Compounds (1) JNK (1) Ligands for Target Protein for PROTAC (1) MAP3K (1) Molecular Glues (1) Neurokinin Receptor (1) NOD-like Receptor (NLR) (1) Nucleoside Antimetabolite/Analog (2) p38 MAPK (1) Parasite (6) PARP (1) Phosphatase (1) PROTAC Linkers (1) PROTACs (2) RAD51 (1) Reactive Oxygen Species (ROS) (1) Reference Standards (2) Ser/Thr Protease (2) Small Interfering RNA (siRNA) (1) STAT (1) Target Protein Ligand-Linker Conjugates (1) TGF-beta/Smad (1) TNF Receptor (3) Topoisomerase (1) VD/VDR (2) VEGFR (1)
By Research Areas:	Cancer (21) Cardiovascular Disease (1) Infection (43) Inflammation/Immunology (14) Metabolic Disease (8) Neurological Disease (4)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1222

LL-37, human Maximum Cited Publications 6 Publications Verification	Bacterial	Infection
LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human could help protect the cornea from infection and modulates wound healing .

HY-12686

5Z-7-Oxozeaenol Maximum Cited Publications 29 Publications Verification FR148083; L783279; LL-Z 1640-2	MAP3K VEGFR Antibiotic	Infection Inflammation/Immunology
5Z-7-Oxozeaenol is a natural anti-protozoan compound from fungal origin, acting as a potent irreversible and selective inhibitor of TAK1 and VEGF-R2, with IC₅₀s of 8 nM and 52 nM, respectively.

HY-P4744

LL-37 amide 2 Publications Verification	Formyl Peptide Receptor (FPR) Bacterial	Infection Cancer
LL-37 amide is a selective agonist of formyl peptide receptor-like FPRL1, effectively inhibiting periodontal pathogens (ED₉₉=8.5-8.7 μg/mL). LL-37 amide exerts its bactericidal effect by activating FPRL1-mediated immune cell chemotaxis and disrupting bacterial cell membrane integrity. It can also regulate inflammatory responses (inhibiting the release of factors such as TNF-α) and promote angiogenesis. Amidation modification reduces its sensitivity to serum inhibition and improves its stability. LL-37 amide possesses key activities in bactericidal action, immunomodulation, and wound healing, and is mainly used in research on infection-related diseases such as periodontal disease and deep tissue injuries (pressure ulcers), and wound healing .

HY-P1222A

LL-37, human TFA Maximum Cited Publications 6 Publications Verification	Bacterial	Infection
LL-37, human TFA is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human TFA could help protect the cornea from infection and modulates wound healing .

HY-112542

Nemadectin CL-287088; LL-F28249 α	Parasite Antibiotic	Infection
Nemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity .

HY-P4855

CRAMP (mouse) 1 Publications Verification	Bacterial TNF Receptor	Infection Inflammation/Immunology
CRAMP (mouse) is an antibacterial peptide and a functional homolog of LL-37 . CRAMP (mouse) exhibits potent antibacterial activity against Gram-negative bacteria . The complex formed by CRAMP (mouse) and CpG can activate macrophages to secrete TNF-α . CRAMP (mouse) plays a key role in wound healing, immune regulation and maintenance of intestinal homeostasis .

HY-32350

Ercalcitriol 3 Publications Verification 1α,25-Dihydroxy Vitamin D2	VD/VDR Drug Metabolite Endogenous Metabolite	Metabolic Disease
Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is a vitamin D receptor (VDR) agonist with high binding affinity. After binding to VDR, Ercalcitriol forms a complex with retinoid X receptor (RXR) to regulate target gene transcription. For example, Ercalcitriol induces human gingival/oral epithelial cells to produce human cat antimicrobial peptide (hCAP-18/LL-37), which has antimicrobial activity against periodontal pathogens such as Porphyromonas gingivalis. Ercalcitriol enhances the innate immune defense of the oral mucosa by promoting the expression of antimicrobial peptides, and is mainly used in the study of periodontal diseases and immune-related oral diseases .

HY-114360

Taurohyodeoxycholic acid 2 Publications Verification	Endogenous Metabolite COX Interleukin Related Glutathione Peroxidase TNF Receptor	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Taurohyodeoxycholic acid is an orally active 6 alpha-hydroxylated bile acid. Taurohyodeoxycholic acid decreases colonic MPO activity, TNF-α, lL-6 serum levels and the expression of COX-2. Taurohyodeoxycholic acid alleviates trinitrobenzene sulfonic acid induced ulcerative colitis via regulating Th1/Th2 and Th17/Treg cells balance. Taurohyodeoxycholic acid ameliorates high-fat diet-induced nonalcoholic fatty liver disease in mice. Taurohyodeoxycholic acid prevents Taurochenodeoxycholic acid (HY-N2027)-induced hepatotoxicity in bile fistula rats. Taurohyodeoxycholic acid can be used for the study of nonalcoholic fatty liver disease (NAFLD), colitis and biliary fistula .

HY-P1222B

LL-37, human acetate Maximum Cited Publications 6 Publications Verification	Bacterial	Infection Inflammation/Immunology
LL-37, human acetate is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human acetate could help protect the cornea from infection and modulates wound healing .

HY-163944

LL-K12-18	DNA/RNA Synthesis Molecular Glues CDK Apoptosis RAD51 ATM/ATR PARP	Cancer
LL-K12-18 is a CDK12 kinase inhibitor and a dual-site molecular glue. LL-K12-18 inhibits human CDK12 with an IC₅₀ value of 283.9 nM, and selectively degrades cyclin K via the ubiquitin-proteasome system by stabilizing the CDK12-DDB1 complex. LL-K12-18 downregulates DNA damage response genes, reduces the phosphorylation level of CTD Ser2 in RNA polymerase II, and modulates biomarkers such as ATM, RAD51, γ-H2AX and cleaved PARP, thereby effectively inducing apoptosis and inhibiting proliferation of breast cancer cells. LL-K12-18 exhibits high target selectivity and serves as a research tool for studies on triple-negative breast cancer .

HY-P1513A

LL-37 scrambled peptide acetate	Bacterial	Infection
LL-37 scrambled peptide acetate is a scrambled version of cathelicidin anti-microbial peptide LL-37. LL-37 scrambled peptide acetate can be used as a negative control of LL-37 peptide studies.

HY-128464

LL320	Amine N-methyltransferase	Metabolic Disease
LL320 is a selective NNMT inhibitor with a K_i,app of 6.8 nM. LL320 exhibits interactions with RNMT, DPH₅, and SAHH .

HY-149209

LL-K8-22	PROTACs CDK STAT Early 2 Factor (E2F)	Cancer
LL-K8-22 is a potent, selective and durable PROTAC CDK8-cyclin C dual degrader, with DC₅₀ values of 2.52 and 2.64 μM, respectively. LL-K8-22 also suppresses STAT1 Ser 727 phosphorylation. LL-K8-22 inhibits E2F- and MYC-driven carcinogenic transcriptional programs. LL-K8-22 can be used for triplenegative breast cancer (TNBC) research. (Pink: Ligand for target protein (HY-168683); Black: Linker (HY-Y0340); Blue: Ligand for E3 ligase (HY-N2427)) .

HY-P10257

KR-12 (human)	Bacterial	Infection
KR-12 (human) is an active segment of LL-37 (HY-P4744). KR-12 (human) exhibits antimicrobial activity against gram-negative bacteria. KR-12 (human) inhibits E. coli K-12 with a MIC of 66 μM. KR-12 human can be used for the research of infection, such as E. coli infection .

HY-18684

SIBA 5'-Isobutylthioadenosine; 5'-Deoxy-5'-isobutylthioadenosine	Nucleoside Antimetabolite/Analog HSV Parasite	Infection Metabolic Disease Cancer
SIBA (5'-Isobutylthioadenosine) is a transmethylation inhibitor (SAH (HY-19528) analogue), with potent anti-proliferative activity. SIBA reversibly inhibits the production of HSV-1 by blocking methylation, specifically by blocking the 5' end-capping of viral mRNA. SIBA also inhibits the growth of tumour cells in vitro and metastatic spread in vivo. SIBA can be used in cancer, HSV-1 infection and anti-malaria studies .

HY-76938

Actarit 4-Acetylaminophenylacetic acid; MS-932	Carbonic Anhydrase TNF Receptor IFNAR	Inflammation/Immunology
Actarit (4-Acetylaminophenylacetic acid) is an orally active Carbonic Anhydrase II (CAII) inhibitor with an IC₅₀ of 422 nM. Actarit shows suppressive effects experimental autoimmune encephalomyelitis in rats. Actarit inhibits the development of type ll collagen (CII)-induced arthritis in mice by suppressing delayed-type hypersensitivity to CII. Actarit can be used for the study of Multiple Sclerosis (MS) and rheumatoid arthritis .

HY-P5391

LL-37(17-32)	Bacterial	Others
LL-37(17-32) is a biological active peptide. (This peptide is an active segment of LL-37, a peptide derived from the C-terminal domain of human cathelicidin antimicrobial peptide. It has been reported that the LL17-32 peptide exhibits reversal effect on ABCG2-mediated multidrug resistance in cancer cell lines.)

HY-P1425

(Z-LL)2 ketone	Ser/Thr Protease	Neurological Disease
(Z-LL)2 ketone is an inhibitor of ketone with an IC₅₀ value of 50 nM. (Z-LL)2 ketone inhibits processing of thep-Prlsignal peptide .

HY-P4744A

LL-37 amide TFA 2 Publications Verification	Formyl Peptide Receptor (FPR) Bacterial	Infection Cancer
LL-37 amide TFA is a selective agonist of formyl peptide receptor-like FPRL1, effectively inhibiting periodontal pathogens (ED₉₉=8.5-8.7 μg/mL). LL-37 amide TFA exerts its bactericidal effect by activating FPRL1-mediated immune cell chemotaxis and disrupting bacterial cell membrane integrity. It can also regulate inflammatory responses (inhibiting the release of factors such as TNF-α) and promote angiogenesis. Amidation modification reduces its sensitivity to serum inhibition and improves its stability. LL-37 amide TFA possesses key activities in bactericidal action, immunomodulation, and wound healing, and is mainly used in research on infection-related diseases such as periodontal disease and deep tissue injuries (pressure ulcers), and wound healing .

HY-109963

PR5-LL-CM01	Histone Methyltransferase	Cancer
PR5-LL-CM01 is a potent protein arginine methyltransferase 5 (PRMT5) inhibitor (IC₅₀= 7.5 μM). Anti-tumor activies .

HY-109589A

trans-11-Eicosenoic acid 1 Publications Verification	Phosphatase Bacterial	Infection
trans-11-Eicosenoic acid is a fatty acid that inhibits the phosphatase activity of PtpA from Mycobacterium tuberculosis, with an IC₅₀ of 27.97 µM. trans-11-Eicosenoic acid is detected in the stems of alfalfa plants inoculated with Sinorhizobium meliloti LL11, but is absent in the stems of uninoculated alfalfa or the strain itself .

HY-18234C

Leupeptin Ac-LL hydrochloride	Biochemical Assay Reagents	Inflammation/Immunology Cancer
Leupeptin Ac-LL (hydrochloride) is the hydrochloride form of Leupeptin Ac-LL (HY-18234B). Leupeptin Ac-LL (hydrochloride) has better inhibition than Leupeptin Ac-LL .

HY-P1884

LL-37, acetylated,amidated	Bacterial	Infection
LL-37, acetylated, amidated is a cathelicidin peptide LL-37 acetylated on the N-terminus and amidated on the C-terminus. The single human cathelicidin peptide LL-37 has antimicrobial and anti-biofilm activity against multiple Gram-positive and Gram-negative human pathogens, and has wound-healing effects on the host .

HY-156084

LL-K9-3	CDK PROTACs Apoptosis c-Myc	Cancer
LL-K9-3 is a potent small-molecule degrader of CDK9-cyclin T1. LL-K9-3 has anti-proliferative and pro-apoptotic activities and suppresses downstream signaling of CDK9 and AR. Moreover, LL-K9-3 inhibits AR and Myc-driven oncogenic transcriptional programs .

HY-N9366

Tumulosic acid 1 Publications Verification	Others	Inflammation/Immunology
Tumulosic acid, a triterpenoid, inhibits KLK5 protease activity (IC₅₀= 14.84 μM). Tumulosic acid suppresses the proteolytic processing of LL-37 in keratinocytes at ≤10 μM .

HY-168683

CDK8 ligand 1	Ligands for Target Protein for PROTAC CDK	Cancer
CDK8 ligand 1 is the ligand of CDK8. CDK8 ligand 1 can be used to synthesize LL-K8-22 (HY-149209) .

HY-P4128

LL-37 SKE	Bacterial Antibiotic	Others
LL-37 SKE is an active fragment of LL-37 .

HY-P4836A

LL-37 FK-13 TFA	Parasite	Infection
LL-37 FK-13 TFA is the TFA salt form of LL-37 FK-13 (HY-P4836). LL-37 FK-13 TFA is an antimicrobial agent, that inhibits Trichomonas vaginalis. LL-37 FK-13 TFA exhibits minimal hemolytic effects on human erythrocytes and low cytotoxicity to human fibroblasts .

HY-P5057A

5-FAM-LL-37 TFA	Fluorescent Dye Bacterial	Infection
5-FAM-LL-37 TFA is the TFA salt form of 5-FAM-LL-37 (HY-P5057). 5-FAM-LL-37 TFA is a LL-37 peptide labeled with fluorescein, which retains the antibacterial and immunomodulatory activities of LL-37. 5-FAM-LL-37 TFA binds to the bacterial cell membrane, destroys the integrity of the membrane, and exhibits board-spectrum antibacterial efficacy .

HY-14990

Sudoterb LL 3858	Bacterial	Infection
Sudoterb (LL 3858) is an orally active anti-Tuberculosis agent .

HY-116863

KKL-40	Bacterial	Infection
KKL-40 is a small molecule inhibitor that targets the trans-transcription process and is effective against methicillin-sensitive and -resistant Staphylococcus aureus (S. aureus) as well as other Gram-positive pathogens including vancomycin-resistant Enterococcus faecium, Bacillus subtilis, and Streptococcus pyogenes. KKL-40 synergizes with the human antimicrobial peptide LL-37 to inhibit S. aureus, but does not synergize with other antibiotics such as daptomycin, kanamycin, or erythromycin. Trans-transcription is an extreme form of recoding, and KKL-40 inhibits trans-transcription but is nontoxic to HeLa cells .

HY-P1513

LL-37 scrambled peptide	Bacterial	Infection
LL-37 scrambled peptide is a scrambled version of cathelicidin anti-microbial peptide LL-37. LL-37 scrambled peptide can be used as a negative control of LL-37 peptide studies.

HY-120349

LL-Z1640-4	p38 MAPK JNK Apoptosis Reactive Oxygen Species (ROS)	Cancer
LL-Z1640-4 is a potent p38/JNK signaling inhibitor. LL-Z1640-4 significantly diminishes p38 and JNK activation in HCC cells transfected with MLK4 siRNA. LL-Z1640-4 markedly attenuates ROS production induced by MLK4 knockdown. LL-Z1640-4 significantly reduces the apoptotic cells in HCC cells transfected with siMLK4 .

HY-P4747

LL-37 GKE	Antibiotic Bacterial	Infection
LL-37 GKE is an active domain of LL-37. LL-37 GKE has antibacterial activity and has potential applications in antibiotics .

HY-P5057

5-FAM-LL-37	Fluorescent Dye Bacterial	Others
5-FAM-LL-37 is afluorescent labeled LL-37, human (HY-P1222).

HY-P4836

LL-37 FK-13	Parasite	Infection
LL-37 FK-13 is an antimicrobial agent, that inhibits Trichomonas vaginalis. LL-37 FK-13 exhibits slight hemolytic effects on human erythrocytes and low cytotoxicity to human fibroblasts .

HY-18234B

Leupeptin Ac-LL	Ser/Thr Protease	Metabolic Disease Inflammation/Immunology Cancer
Leupeptin Ac-LL is a protease inhibitor from actinomycetes. Leupeptin Ac-LL has antiplasmin activity .

HY-P5057B

5-FAM-Ahx-LL-37 TFA	Fluorescent Dye Bacterial	Infection
5-FAM-Ahx-LL-37 TFA is a 5-FAM (HY-66022) labeled LL-37, human (HY-P1222). The carboxyfluorescein group is attached via a 6-carbon spacer, 6-Aminohexanoic acid (Ahx, HY-B0236). LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity .

HY-113561

Biphenomycin A LL-AF283α	Antibiotic Bacterial	Infection
Biphenomycin A (LL-AF283α) is a cyclic peptide antibiotic that can be found in Streptomyces griseorubiginosus 43708. It has antibacterial activity and can be used in research in the field of anti-infection .

HY-117845

Citreamicin alpha LL-E19085α	Antibiotic Bacterial	Infection
Citreamicin alpha (LL-E 19085-alpha) is an antibiotic whose in vitro antimicrobial activity against 429 clinical isolates of Gram-positive cocci has been tested by the agar dilution method. These microorganisms included 313 strains of Staphylococci and 116 strains of Streptococci. The in vitro activity of Citreamicin alpha was compared with that of ampicillin, amoxicillin, ceftriaxone, erythromycin, and vancomycin. For Staphylococci, the MIC values of Citreamicin alpha ranged from 0.12-4.0 μg/ml, and for Streptococcus pyogenes of the genus Streptococcus, it was 0.03-0.12 μg/ml. However, enterococci were relatively resistant, requiring 2.0 μg/ml of the agent to inhibit 64% of the 62 tested strains. The in vitro activity of this antibiotic was much better than that of ampicillin, amoxicillin, ceftriaxone, and erythromycin, but comparable or slightly inferior to that of vancomycin.

HY-P10345

OP-145	Bacterial	Infection
OP-145, an cathelicidin LL-37 derivative, is an antimicrobial peptide, and shows antibacterial activity against several MRSA strains. OP-145 can be used for research of chronic suppurative otitis media .

HY-W037980

Succinamic acid	PROTAC Linkers	Metabolic Disease Cancer
Succinamic acid is a weak inhibitor for human LL-xylose reductase with an IC₅₀ of 1.45 mM. Succinamic acid can be used as a linker for synthesis of CQ-16 (HY-169336) .

HY-P5525

AC3-I, myristoylated Autocamtide-3 Derived Inhibitory Peptide	CaMK	Others
AC3-I, myristoylated is a biological active peptide. (This is a myristoylated form of Autocamtide-3-Derived Inhibitory Peptide (AC3-I), a highly specific inhibitor of Calmodulin-Dependent Protein Kinase ll (CaMKII) that is resistant to proteolysis. AC3-I is derived from Autocamtide-3, a substrate for CaMKII, with the Thr-9 phosphorylation site substituted with Ala.)

HY-P5729

LL-25	Fungal	Infection
LL-25 is a fragment of LL-37 (HY-P1222) but devoid of the immunomodulatory properties of LL-37. LL-25 has antifungal and candidacidal activity .

HY-175662

TGF-β/Smad-IN-2	TGF-beta/Smad	Inflammation/Immunology
TGF-β/Smad-IN-2 is an orally active TGF-β/Smad inhibitor. TGF-β/Smad-IN-2 inhibits TGF-β-induced fibroblast-to-myofibroblast differentiation and collagen deposition, with an IC₅₀ value of 102 μM for collagen reduction in LL29 cells. TGF-β/Smad-IN-2 exerts its effects through modulation of the SMAD3/SMAD7 signaling pathway. TGF-β/Smad-IN-2 reduces lung index in pulmonary fibrosis mice. TGF-β/Smad-IN-2 can be used for the study of pulmonary fibrosis .

HY-P4746

LL-37 FKR	Bacterial	Infection
LL-37 FKR is the C-terminal fragment of LL-37. LL-37 FKR plays an important role in antibacterial performance .

HY-P4751

LL-37 RKS	Bacterial	Others
LL-37 RKS is an active fragment of LL-37 .

HY-P10262

LL-37-Cys	Drug Derivative	Others
LL-37-Cys is a LL-37 (HY-P1222) with a C-terminal reduced cystein residue ^[1][.

HY-P5837

Citrullinated LL-37 2cit	Interleukin Related Enterovirus	Inflammation/Immunology
Citrullinated LL-37 2cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 2cit reduces LL-37 activity against HRV at 10 μg/mL and reduces the antibacterial effect of LL-37. Citrullinated LL-37 2cit causes a reduction in the levels of IL-8, CCL5, and IL-6 mRNA induced by RV1B. Citrullinated LL-37 2cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion .

HY-P5843

Citrullinated LL-37 4cit	Enterovirus	Infection
Citrullinated LL-37 3cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 3cit lacks all antiviral activity at 10 μg/mL and retains some activity against HRV at 30 μg/mL. Citrullinated LL-37 3cit reduces the immunomodulatory activity of LL-37. Citrullinated LL-37 3cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion .

Cat. No.	Product Name	Type

HY-109589A

trans-11-Eicosenoic acid 1 Publications Verification	Biochemical Assay Reagents
trans-11-Eicosenoic acid is a fatty acid that inhibits the phosphatase activity of PtpA from Mycobacterium tuberculosis, with an IC₅₀ of 27.97 µM. trans-11-Eicosenoic acid is detected in the stems of alfalfa plants inoculated with Sinorhizobium meliloti LL11, but is absent in the stems of uninoculated alfalfa or the strain itself .

HY-18234C

Leupeptin Ac-LL hydrochloride	Biochemical Assay Reagents
Leupeptin Ac-LL (hydrochloride) is the hydrochloride form of Leupeptin Ac-LL (HY-18234B). Leupeptin Ac-LL (hydrochloride) has better inhibition than Leupeptin Ac-LL .

Cat. No.	Product Name	Target	Research Area

HY-P1222

LL-37, human Maximum Cited Publications 6 Publications Verification	Bacterial	Infection
LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human could help protect the cornea from infection and modulates wound healing .

HY-P4744

LL-37 amide 2 Publications Verification	Formyl Peptide Receptor (FPR) Bacterial	Infection Cancer
LL-37 amide is a selective agonist of formyl peptide receptor-like FPRL1, effectively inhibiting periodontal pathogens (ED₉₉=8.5-8.7 μg/mL). LL-37 amide exerts its bactericidal effect by activating FPRL1-mediated immune cell chemotaxis and disrupting bacterial cell membrane integrity. It can also regulate inflammatory responses (inhibiting the release of factors such as TNF-α) and promote angiogenesis. Amidation modification reduces its sensitivity to serum inhibition and improves its stability. LL-37 amide possesses key activities in bactericidal action, immunomodulation, and wound healing, and is mainly used in research on infection-related diseases such as periodontal disease and deep tissue injuries (pressure ulcers), and wound healing .

HY-P1222A

LL-37, human TFA Maximum Cited Publications 6 Publications Verification	Bacterial	Infection
LL-37, human TFA is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human TFA could help protect the cornea from infection and modulates wound healing .

HY-P4855

CRAMP (mouse) 1 Publications Verification	Bacterial TNF Receptor	Infection Inflammation/Immunology
CRAMP (mouse) is an antibacterial peptide and a functional homolog of LL-37 . CRAMP (mouse) exhibits potent antibacterial activity against Gram-negative bacteria . The complex formed by CRAMP (mouse) and CpG can activate macrophages to secrete TNF-α . CRAMP (mouse) plays a key role in wound healing, immune regulation and maintenance of intestinal homeostasis .

HY-P0131A

Laminin peptide CDPGYIGSR TFA Laminin (925-933) TFA	Peptides	Cancer
Laminin peptide CDPGYIGSR (Laminin (925-933)) TFA is a 67 kDa laminin receptor ligand and selective cell adhesion inducer. Laminin peptide CDPGYIGSR TFA not only promotes cell adhesion and mediates directed neurite outgrowth via matrix coating or covalent immobilization, but also inhibits neural crest cell migration under specific conditions. Laminin peptide CDPGYIGSR TFA inhibits lung colonization of melanoma cells, and suppresses the growth of Sarcoma 180 solid tumors and Lewis lung carcinoma (3LL) in mice. Laminin peptide CDPGYIGSR TFA also exerts significant anti-angiogenic effects by inhibiting embryonic angiogenesis in the chick chorioallantoic membrane and vascular endothelial cell migration induced by tumor-conditioned medium. Laminin peptide CDPGYIGSR TFA can be widely used in studies related to melanoma, Sarcoma 180, Lewis lung carcinoma (3LL), and other relevant areas .

HY-P1222B

LL-37, human acetate Maximum Cited Publications 6 Publications Verification	Bacterial	Infection Inflammation/Immunology
LL-37, human acetate is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human acetate could help protect the cornea from infection and modulates wound healing .

HY-P1513A

LL-37 scrambled peptide acetate	Bacterial	Infection
LL-37 scrambled peptide acetate is a scrambled version of cathelicidin anti-microbial peptide LL-37. LL-37 scrambled peptide acetate can be used as a negative control of LL-37 peptide studies.

HY-P10257

KR-12 (human)	Bacterial	Infection
KR-12 (human) is an active segment of LL-37 (HY-P4744). KR-12 (human) exhibits antimicrobial activity against gram-negative bacteria. KR-12 (human) inhibits E. coli K-12 with a MIC of 66 μM. KR-12 human can be used for the research of infection, such as E. coli infection .

HY-P5391

LL-37(17-32)	Bacterial	Others
LL-37(17-32) is a biological active peptide. (This peptide is an active segment of LL-37, a peptide derived from the C-terminal domain of human cathelicidin antimicrobial peptide. It has been reported that the LL17-32 peptide exhibits reversal effect on ABCG2-mediated multidrug resistance in cancer cell lines.)

HY-P1425

(Z-LL)2 ketone	Ser/Thr Protease	Neurological Disease
(Z-LL)2 ketone is an inhibitor of ketone with an IC₅₀ value of 50 nM. (Z-LL)2 ketone inhibits processing of thep-Prlsignal peptide .

HY-P4744A

LL-37 amide TFA 2 Publications Verification	Formyl Peptide Receptor (FPR) Bacterial	Infection Cancer
LL-37 amide TFA is a selective agonist of formyl peptide receptor-like FPRL1, effectively inhibiting periodontal pathogens (ED₉₉=8.5-8.7 μg/mL). LL-37 amide TFA exerts its bactericidal effect by activating FPRL1-mediated immune cell chemotaxis and disrupting bacterial cell membrane integrity. It can also regulate inflammatory responses (inhibiting the release of factors such as TNF-α) and promote angiogenesis. Amidation modification reduces its sensitivity to serum inhibition and improves its stability. LL-37 amide TFA possesses key activities in bactericidal action, immunomodulation, and wound healing, and is mainly used in research on infection-related diseases such as periodontal disease and deep tissue injuries (pressure ulcers), and wound healing .

HY-P1884

LL-37, acetylated,amidated	Bacterial	Infection
LL-37, acetylated, amidated is a cathelicidin peptide LL-37 acetylated on the N-terminus and amidated on the C-terminus. The single human cathelicidin peptide LL-37 has antimicrobial and anti-biofilm activity against multiple Gram-positive and Gram-negative human pathogens, and has wound-healing effects on the host .

HY-P4128

LL-37 SKE	Bacterial Antibiotic	Others
LL-37 SKE is an active fragment of LL-37 .

HY-P4836A

LL-37 FK-13 TFA	Parasite	Infection
LL-37 FK-13 TFA is the TFA salt form of LL-37 FK-13 (HY-P4836). LL-37 FK-13 TFA is an antimicrobial agent, that inhibits Trichomonas vaginalis. LL-37 FK-13 TFA exhibits minimal hemolytic effects on human erythrocytes and low cytotoxicity to human fibroblasts .

HY-P5057A

5-FAM-LL-37 TFA	Fluorescent Dye Bacterial	Infection
5-FAM-LL-37 TFA is the TFA salt form of 5-FAM-LL-37 (HY-P5057). 5-FAM-LL-37 TFA is a LL-37 peptide labeled with fluorescein, which retains the antibacterial and immunomodulatory activities of LL-37. 5-FAM-LL-37 TFA binds to the bacterial cell membrane, destroys the integrity of the membrane, and exhibits board-spectrum antibacterial efficacy .

HY-P1513

LL-37 scrambled peptide	Bacterial	Infection
LL-37 scrambled peptide is a scrambled version of cathelicidin anti-microbial peptide LL-37. LL-37 scrambled peptide can be used as a negative control of LL-37 peptide studies.

HY-P4741

LL-37 (37-1)	Peptides	Others
LL-37 (37-1) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4747

LL-37 GKE	Antibiotic Bacterial	Infection
LL-37 GKE is an active domain of LL-37. LL-37 GKE has antibacterial activity and has potential applications in antibiotics .

HY-P5057

5-FAM-LL-37	Fluorescent Dye Bacterial	Others
5-FAM-LL-37 is afluorescent labeled LL-37, human (HY-P1222).

HY-P4836

LL-37 FK-13	Parasite	Infection
LL-37 FK-13 is an antimicrobial agent, that inhibits Trichomonas vaginalis. LL-37 FK-13 exhibits slight hemolytic effects on human erythrocytes and low cytotoxicity to human fibroblasts .

HY-18234B

Leupeptin Ac-LL	Ser/Thr Protease	Metabolic Disease Inflammation/Immunology Cancer
Leupeptin Ac-LL is a protease inhibitor from actinomycetes. Leupeptin Ac-LL has antiplasmin activity .

HY-P5057B

5-FAM-Ahx-LL-37 TFA	Fluorescent Dye Bacterial	Infection
5-FAM-Ahx-LL-37 TFA is a 5-FAM (HY-66022) labeled LL-37, human (HY-P1222). The carboxyfluorescein group is attached via a 6-carbon spacer, 6-Aminohexanoic acid (Ahx, HY-B0236). LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity .

HY-P10345

OP-145	Bacterial	Infection
OP-145, an cathelicidin LL-37 derivative, is an antimicrobial peptide, and shows antibacterial activity against several MRSA strains. OP-145 can be used for research of chronic suppurative otitis media .

HY-P5525

AC3-I, myristoylated Autocamtide-3 Derived Inhibitory Peptide	CaMK	Others
AC3-I, myristoylated is a biological active peptide. (This is a myristoylated form of Autocamtide-3-Derived Inhibitory Peptide (AC3-I), a highly specific inhibitor of Calmodulin-Dependent Protein Kinase ll (CaMKII) that is resistant to proteolysis. AC3-I is derived from Autocamtide-3, a substrate for CaMKII, with the Thr-9 phosphorylation site substituted with Ala.)

HY-P5729

LL-25	Fungal	Infection
LL-25 is a fragment of LL-37 (HY-P1222) but devoid of the immunomodulatory properties of LL-37. LL-25 has antifungal and candidacidal activity .

HY-P4746

LL-37 FKR	Bacterial	Infection
LL-37 FKR is the C-terminal fragment of LL-37. LL-37 FKR plays an important role in antibacterial performance .

HY-P4751

LL-37 RKS	Bacterial	Others
LL-37 RKS is an active fragment of LL-37 .

HY-P4748

LL-21 LL-37 LLG	Peptides	Others
LL-21 (LL-37 LLG) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P10262

LL-37-Cys	Drug Derivative	Others
LL-37-Cys is a LL-37 (HY-P1222) with a C-terminal reduced cystein residue ^[1][.

HY-P5837

Citrullinated LL-37 2cit	Interleukin Related Enterovirus	Inflammation/Immunology
Citrullinated LL-37 2cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 2cit reduces LL-37 activity against HRV at 10 μg/mL and reduces the antibacterial effect of LL-37. Citrullinated LL-37 2cit causes a reduction in the levels of IL-8, CCL5, and IL-6 mRNA induced by RV1B. Citrullinated LL-37 2cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion .

HY-P5843

Citrullinated LL-37 4cit	Enterovirus	Infection
Citrullinated LL-37 3cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 3cit lacks all antiviral activity at 10 μg/mL and retains some activity against HRV at 30 μg/mL. Citrullinated LL-37 3cit reduces the immunomodulatory activity of LL-37. Citrullinated LL-37 3cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion .

HY-P5838

Citrullinated LL-37 5cit	Bacterial	Inflammation/Immunology
Citrullinated LL-37 5cit is a citrullinated LL-37 (HY-P1222) peptide. The antiviral and antibacterial effects of Citrullinated LL-37 5cit are significantly reduced compared to native LL-37. Citrullinated LL-37 5cit is unable to reduce LPS-mediated release of TNF-α due to a lack of LPS-binding capacity .

HY-P5836

Citrullinated LL-37 1cit	Interleukin Related Bacterial Enterovirus	Inflammation/Immunology
Citrullinated LL-37 1cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 1cit does not alter the antiviral effect of LL-37 toward human rhinovirus. Citrullinated LL-37 1cit shows antibacterial activity toward S. aureus. Citrullinated LL-37 1cit causes a reduction in the levels of IL-8, CCL5, and IL-6 mRNA induced by RV1B .

HY-P4799

LL-37 KR20	Drug Derivative	Others
LL-37 KR20 is aLL 37 derivative.

HY-P5842

Citrullinated LL-37 3cit	Bacterial Influenza Virus	Infection
Citrullinated LL-37 3cit is a host defense peptide (HDP) with broad immunomodulatory and antimicrobial activities. Citrullinated LL-37 3cit exhibits direct antiviral effects against human rhinoviruses (HRV) .

HY-P10306

Cys-LL37	Bacterial	Infection
Cys-LL37 is a biomaterial with antimicrobial properties developed by covalently fixing to the surface of titanium. Cys-LL37 uses a flexible hydrophilic polyethylene glycol spacer and selective n-terminal coupling LL37, a surface peptide layer that kills bacteria on contact is formed. Cys-LL37 can be used in research to develop new antimicrobial biomaterials .

HY-P11457

cCBD-LL37	Bacterial	Infection
cCBD-LL37 is a chimeric antimicrobial peptide modified with a collagen-binding domain (cCBD) (TKKTLRT). cCBD-LL37 has improved retention on collagen after PBS washing and varying electrostatic conditions. cCBD-LL37 binds to collagen involves both specific and non-specific interactions, initiated by long-range electrostatic forces that transitions to close range or hydrophobic interactions. cCBD-LL37 has potent antimicrobial activity with improved structural stability under different ionic strengths and pH conditions (pH 5.5-8). cCBD-LL37 can be used for biomaterials like collagen-based wound dressings research .

HY-P5076

Biotinyl-LL-37	Peptides	Others
Biotinyl-LL-37 is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4734

5-FAM-LL-37 (scrambled)	Peptides	Others
5-FAM-LL-37 (scrambled) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P5829A

CRAMP (140-173) (mouse) TFA	Bacterial	Infection
CRAMP (140-173) (mouse) TFA is a ortholog of human *LL-37* antimicrobial peptide. CRAMP (140-173) (mouse) TFA inhibits LPS (HY-D1056)-induced responses, and can not colocalized with TLR3 in BEAS-2B cells .

HY-P3554

Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl	HIV	Infection
Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl (compound (CPF(LL)) is an HIV-1 inhibitor. Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl interacts with gp120 to block gp120 binding to CD4 and preserve CD4-dependent T cell function .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-12686

5Z-7-Oxozeaenol Maximum Cited Publications 29 Publications Verification FR148083; L783279; LL-Z 1640-2	Natural Products Monophenols Microorganisms Classification of Application Fields Phenols Inflammation/Immunology Disease Research Fields Source Classification	MAP3K VEGFR Antibiotic
5Z-7-Oxozeaenol is a natural anti-protozoan compound from fungal origin, acting as a potent irreversible and selective inhibitor of TAK1 and VEGF-R2, with IC₅₀s of 8 nM and 52 nM, respectively.

HY-112542

Nemadectin CL-287088; LL-F28249 α	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Anti-parasitic Disease Research Disease Research Fields Source Classification	Parasite Antibiotic
Nemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity .

HY-32350

Ercalcitriol 3 Publications Verification 1α,25-Dihydroxy Vitamin D2	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	VD/VDR Drug Metabolite Endogenous Metabolite
Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is a vitamin D receptor (VDR) agonist with high binding affinity. After binding to VDR, Ercalcitriol forms a complex with retinoid X receptor (RXR) to regulate target gene transcription. For example, Ercalcitriol induces human gingival/oral epithelial cells to produce human cat antimicrobial peptide (hCAP-18/LL-37), which has antimicrobial activity against periodontal pathogens such as Porphyromonas gingivalis. Ercalcitriol enhances the innate immune defense of the oral mucosa by promoting the expression of antimicrobial peptides, and is mainly used in the study of periodontal diseases and immune-related oral diseases .

HY-114360

Taurohyodeoxycholic acid 2 Publications Verification	Structural Classification Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Steroids Source Classification	Endogenous Metabolite COX Interleukin Related Glutathione Peroxidase TNF Receptor
Taurohyodeoxycholic acid is an orally active 6 alpha-hydroxylated bile acid. Taurohyodeoxycholic acid decreases colonic MPO activity, TNF-α, lL-6 serum levels and the expression of COX-2. Taurohyodeoxycholic acid alleviates trinitrobenzene sulfonic acid induced ulcerative colitis via regulating Th1/Th2 and Th17/Treg cells balance. Taurohyodeoxycholic acid ameliorates high-fat diet-induced nonalcoholic fatty liver disease in mice. Taurohyodeoxycholic acid prevents Taurochenodeoxycholic acid (HY-N2027)-induced hepatotoxicity in bile fistula rats. Taurohyodeoxycholic acid can be used for the study of nonalcoholic fatty liver disease (NAFLD), colitis and biliary fistula .

HY-18234C

Leupeptin Ac-LL hydrochloride	Natural Products Microorganisms Source Classification	Biochemical Assay Reagents
Leupeptin Ac-LL (hydrochloride) is the hydrochloride form of Leupeptin Ac-LL (HY-18234B). Leupeptin Ac-LL (hydrochloride) has better inhibition than Leupeptin Ac-LL .

HY-N9366

Tumulosic acid 1 Publications Verification	Triterpenes Classification of Application Fields Terpenoids Polyporaceae Poria cocos Plants Inflammation/Immunology Disease Research Fields Source Classification	Others
Tumulosic acid, a triterpenoid, inhibits KLK5 protease activity (IC₅₀= 14.84 μM). Tumulosic acid suppresses the proteolytic processing of LL-37 in keratinocytes at ≤10 μM .

HY-113561

Biphenomycin A LL-AF283α	Microorganisms Macrolide Antibiotics Antibiotics Phenols Polyphenols Source Classification	Antibiotic Bacterial
Biphenomycin A (LL-AF283α) is a cyclic peptide antibiotic that can be found in Streptomyces griseorubiginosus 43708. It has antibacterial activity and can be used in research in the field of anti-infection .

HY-117845

Citreamicin alpha LL-E19085α	Structural Classification Microorganisms Antibiotics Source Classification	Antibiotic Bacterial
Citreamicin alpha (LL-E 19085-alpha) is an antibiotic whose in vitro antimicrobial activity against 429 clinical isolates of Gram-positive cocci has been tested by the agar dilution method. These microorganisms included 313 strains of Staphylococci and 116 strains of Streptococci. The in vitro activity of Citreamicin alpha was compared with that of ampicillin, amoxicillin, ceftriaxone, erythromycin, and vancomycin. For Staphylococci, the MIC values of Citreamicin alpha ranged from 0.12-4.0 μg/ml, and for Streptococcus pyogenes of the genus Streptococcus, it was 0.03-0.12 μg/ml. However, enterococci were relatively resistant, requiring 2.0 μg/ml of the agent to inhibit 64% of the 62 tested strains. The in vitro activity of this antibiotic was much better than that of ampicillin, amoxicillin, ceftriaxone, and erythromycin, but comparable or slightly inferior to that of vancomycin.

HY-114749

LL-C 10037α	Monophenols Microorganisms Phenols Source Classification	Antibiotic Bacterial
LL-C 10037α is an antitumor antibiotic and can be isolated from Streptomyces .

HY-130214

7-Hydroxypestalotin LL-P880β	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Disease Research Fields Source Classification	Endogenous Metabolite
7-Hydroxypestalotin (LL-P880β) is a fungal metabolite .

HY-114708

Ilicicolin B LL-Z 1272β	Monophenols Microorganisms Phenols Source Classification	Bacterial
Ilicicolin B (LL-Z 1272β) inhibits Bacillus carbonifera with the concentration of 6 μg/mL and its toxic concentration to Hela cells is 0.3 μg/mL .

HY-119552

Acetylaszonalenin LL-S490β	Alkaloids Microorganisms Indole Alkaloids Source Classification	Endogenous Metabolite Neurokinin Receptor
Acetylaszonalenin, a prenylated indole derivative, is a fungal metabolite.Acetylaszonalenin is a potent neurokinin-1 (NK1) receptor antagonist. Acetylaszonalenin shows inhibition of [ ³H]-SP binding to human astrocytoma cells with a K_i of 170 μM .

HY-122108

Ilicicolin A LL-Z 1272-alpha	Microorganisms Phenols Polyphenols Source Classification	Apoptosis
Ilicicolin A is a potent anticancer agent. Ilicicolin A induces apoptosis. Ilicicolin A inhibits cell growth and colony formation. Ilicicolin A shows antitumor activity. Ilicicolin A has the potential for the research of prostate cancer .

HY-106843

Phospholine	Natural Products Microorganisms Source Classification	Antibiotic Bacterial
Phospholine is an antibiotic. The IC₅₀ (μg/mL) of Ll 210, P388 and EL-4 cells are 3.37, 2.20 and 1.99, respectively .

HY-111333

Pyrroxamycin Dioxapyrrolomycin; LL-F42248α; AL-R2081	Microorganisms Antibiotics Source Classification	Bacterial
Pyrroxamycin is a novel antibiotic produced by Streptomyces, whose chemical structure was determined by chemical properties and X-ray crystallography and 13C NMR spectroscopy analysis. It is active against Gram-positive bacteria and dermatophytes. In this paper, the authors discuss the taxonomy, fermentation, isolation, physicochemical properties, chemical structure, and biological activity of the strain producing Pyrroxamycin.

HY-112542R

Nemadectin (Standard) CL-287088 (Standard); LL-F28249 α (Standard)	Microorganisms Macrolide Antibiotics Antibiotics Anti-parasitic Disease Research Source Classification	Reference Standards Parasite Antibiotic
Nemadectin (Standard) is the analytical standard of Nemadectin. This product is intended for research and analytical applications. Nemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity .

HY-121716

Pelagiomicin A Antibiotic 2088A; LL-14I352α	Antibiotics Marine natural products Source Classification	Bacterial
Pelagiomicin A is a novel phenazine antibiotic produced by the marine bacterium Pelagiobacter variabilis. The compound is unstable in water and small alcohols. The absolute structure of its major component, Pelagiomicin A, as well as the properties of minor amounts of other structures, were determined by spectroscopic data and synthesis. Pelagiomicin A is active against both Gram-positive and Gram-negative bacteria and exhibits antitumor activity in vitro and in vivo.

HY-123379

Relomycin Tylosin D; LL-AM 684B	Microorganisms Antibiotics Source Classification	Others
Relomycin is an active compound.

HY-180692

(S)-2-Acetamido-6-oxopimelic acid	Structural Classification Natural Products Endogenous metabolite Source Classification	Nucleoside Antimetabolite/Analog
(S)-2-Acetamido-6-oxopimelic acid (compound 1b) is a substrate of N-Succinyl-ll-diaminopimelate aminotransferase (DAP-AT) .

Tag:	His (1) Tag Free (1)
Source:	E. coli (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P702136

	Acetylornithine Deacylase Protein, Shigella sonnei dapE; Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2; 6-diaminoheptanedioate amidohydrolase	Others	E. coli
	Acetylornithine deacylase protein catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), leading to the formation of succinic acid and LL-2,6-diaminopimelic acid (DAP) , plays a key role in cellular processes. This enzyme activity is integral to the bacterial biosynthesis of lysine and mesodiaminopimelic acid, both of which contribute to the structural integrity of the bacterial cell wall. Acetylornithine Deacylase Protein, Shigella sonnei is the recombinant Acetylornithine Deacylase protein, expressed by E. coli , with tag free.

HY-P702137

	Acetylornithine Deacylase Protein, Shigella sonnei (His) dapE; Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2; 6-diaminoheptanedioate amidohydrolase	Others	E. coli
	Acetylornithine deacylase protein catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), leading to the formation of succinic acid and LL-2,6-diaminopimelic acid (DAP) , plays a key role in cellular processes. This enzyme activity is integral to the bacterial biosynthesis of lysine and mesodiaminopimelic acid, both of which contribute to the structural integrity of the bacterial cell wall. Acetylornithine Deacylase Protein, Shigella sonnei (His) is the recombinant Acetylornithine Deacylase protein, expressed by E. coli , with N-6*His labeled tag.

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HY-32350S1

Ercalcitriol-d3

Ercalcitriol-d₃ (1α,25-Dihydroxy Vitamin D2-d₃) is the deuterium labeled Ercalcitriol (HY-32350). Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is a vitamin D receptor (VDR) agonist with high binding affinity. After binding to VDR, Ercalcitriol forms a complex with retinoid X receptor (RXR) to regulate target gene transcription. For example, Ercalcitriol induces human gingival/oral epithelial cells to produce human cat antimicrobial peptide (hCAP-18/LL-37), which has antimicrobial activity against periodontal pathogens such as Porphyromonas gingivalis. Ercalcitriol enhances the innate immune defense of the oral mucosa by promoting the expression of antimicrobial peptides, and is mainly used in the study of periodontal diseases and immune-related oral diseases .

Host:	Mouse (2) Rabbit (2)
Reactivity:	Human (4)
Application:	IHC-P (4) IP (2) WB (2)
Isotype:	IgG (2) IgG1 (2)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

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HY-P89069

	PLCXD1 Antibody (YA8753) LL0XNC01-136G2.1	IHC-P	Human
	PLCXD1 Antibody (YA8753) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PLCXD1.

HY-P89069A

	PLCXD1 Antibody (YA8753)(PBS only) LL0XNC01-136G2.1	IHC-P	Human
	PLCXD1 Antibody (YA8753) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PLCXD1.

HY-P82635

	Cathelicidin Antibody (YA2380) LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39	WB, IHC-P, IP	Human
	Cathelicidin Antibody (YA2380) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cathelicidin.

HY-P82635A

	Cathelicidin Antibody (YA2380)(PBS only) LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39	WB, IHC-P, IP	Human
	Cathelicidin Antibody (YA2380) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cathelicidin.

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