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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
35 Results for "
A549 human carcinoma cells
" in MedChemExpress (MCE) Product Catalog:
Products (35)
35 Results for "A549 human carcinoma cells" in MCE Product Catalog:
2
2 Cited Publications
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KDM4C-IN-1 is a histone lysine demethylase KDM4C inhibitor with an IC50 of 8 nM. KDM4C-IN-1 inhibits cancer cell proliferation. KDM4C-IN-1 can be used in the research of hepatocellular carcinoma and adenocarcinoma alveolar basal epithelial carcinoma .
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β-Tocotrienol is an isomer of vitamin E. β-Tocotrienol is a less potent antioxidant than α-tocotrienol. β-Tocotrienol can be found in the tocotrienol-rich fraction (TRF) of palm oil, which possesses anti-carcinogenic effects in vitro on human colon carcinoma and prostate cancer cells. β-Tocotrienol inhibits the growth of A549 (GI50 = 1.38 μM) and U87MG (GI50 = 2.53 μM) cells. β-Tocotrienol also induces apoptosis in cancer cells. β-Tocotrienol can inhibit PD-L1 expression and mitigates PD-L1-mediated immune suppression in vitro and in vivo .
Cat. No.: HY-D1078
CAS No.: 127770-45-0
Cat. No.: HY-116038
CAS No.: 21688-61-9
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Cat. No.: HY-N2135
CAS No.: 114240-18-5
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other families Flavonoids Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Isoflavones
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Cat. No.: HY-P991196
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Anti-CD24 Antibody (SWA11) is a human IgG1 monoclonal antibody targeting CD24, with high affinity and specificity for CD24-expressing tumor cells. Anti-CD24 Antibody (SWA11) triggers endocytosis, alters STAT3-dependent gene expression, regulates Src phosphorylation, and blocks CD24-mediated signaling pathways. Anti-CD24 Antibody (SWA11) is applicable to cancer-related research such as lung cancer and ovarian cancer. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
Cat. No.: HY-N8420
CAS No.: 21796-15-6
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Infection Alkaloids Monophenols Phenols Plants Disease Research Fields Isoquinoline Alkaloids Menispermaceae Menispermum dauricum
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Cat. No.: HY-W002798
CAS No.: 139631-62-2
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Cyclopropanesulfonyl chloride is a sulfonyl chloride reagent and synthetic building block, which serves as an intermediate for organic synthesis-related research .
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Adrenergic Receptor ERK JNK p38 MAPK NF-κB AP-1 Apoptosis Reactive Oxygen Species (ROS) Mitochondrial Metabolism TNF Receptor
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Desipramine is a first-generation tricyclic antidepressant. Desipramine selectively binds to norepinephrine transporter and blocks neuronal norepinephrine reuptake. Desipramine activates MAPK signaling via ERK1/2, JNK, and p38, represses NF-κB and AP-1 activity, and induces apoptosis via ROS elevation, mitochondrial membrane potential reduction, and intracellular calcium increase. Desipramine also shows anyi-inflammatory activity, inhibiting TNF-α production. Desipramine can be used for the research of hepatocellular cancer, inflammation, and neurological diseases .
(–)-Cryptopleurine is an alkaloid that has been found in Lauraceae and has diverse biological activities. It inhibits the growth of human A375 melanoma, A431 epidermoid carcinoma, A549 lung, MES-SA uterine sarcoma, and MCF-7 breast cancer cells (IC50=3 nM for all).2 (–)-Cryptopleurine inhibits hypoxia-induced gene expression in a hypoxia response element (HRE) reporter assay (IC50=8.7 nM).3 (–)-Cryptopleurine (500 μg/mL) prevents lesion formation in tobacco (N. tabacum) plants infected with tobacco mosaic virus (TMV). It also inhibits protein synthesis by yeast and mammalian ribosomes.
Cat. No.: HY-155231
Neutrophil elastase inhibitor 4 is a human neutrophil elastase (HNE) inhibitor with an IC50 of 21.78 nM and a Ki of 8.04 nM. Neutrophil elastase inhibitor 4 induces G2/M cell cycle arrest and apoptosis. Neutrophil elastase inhibitor 4 is applicable to research related to breast cancer, multiple myeloma and non-small cell lung cancer .
Cat. No.: HY-W778423
CAS No.: 111321-67-6
Synonyms: Dihydroxy Oxaliplatin-Pt(IV)
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[Pt(DACH)(OH)2(ox)] is a Pt(IV) derivative of Oxaliplatin (HY-17371) with two axial hydroxido ligands, used as a precursor for synthesizing Pt(IV)-HDAC inhibitor prodrugs. [Pt(DACH)(OH)2(ox)] exerts cytotoxic activity against human cancer cells and accumulates in cancer cells for nuclear internalization and nuclear DNA platination. [Pt(DACH)(OH)2(ox)] can be used for the research of lung carcinoma, breast carcinoma, pancreatic carcinoma, colon carcinoma .
Cat. No.: HY-108693R
CAS No.: 490-23-3
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β-Tocotrienol (Standard) is the analytical standard of β-Tocotrienol. This product is intended for research and analytical applications. β-Tocotrienol is an isomer of vitamin E. β-Tocotrienol is a less potent antioxidant than α-tocotrienol. β-Tocotrienol can be found in the tocotrienol-rich fraction (TRF) of palm oil, which possesses anti-carcinogenic effects in vitro on human colon carcinoma and prostate cancer cells. β-Tocotrienol inhibits the growth of A549 (GI50 = 1.38 μM) and U87MG (GI50 = 2.53 μM) cells. β-Tocotrienol also induces apoptosis in cancer cells. β-Tocotrienol can inhibit PD-L1 expression and mitigates PD-L1-mediated immune suppression in vitro and in vivo .
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Antioxidant agent-11 is a 2-pyrazole-2,3-dihydroquinazolin-4(1H)-one derivative and a weak antioxidant. Antioxidant agent-11 scavenges DPPH free radicals. Antioxidant agent-11 can be used for the research of lung carcinoma .
Cat. No.: HY-N17744
CAS No.: 1431563-59-5
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Cat. No.: HY-W353474
CAS No.: 22214-39-7
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iso-Dehydrozingerone is a dehydrozingerone analog. iso-Dehydrozingerone exhibits moderate in vitro cytotoxic activity against human tumor cells, with IC50 values of 10.0 μg/mL, 8.2 μg/mL and >10 μg/mL against human nasopharyngeal carcinoma cells, multidrug-resistant nasopharyngeal carcinoma cells and human lung cancer cells, respectively. iso-Dehydrozingerone can be used in studies related to nasopharyngeal carcinoma, multidrug-resistant nasopharyngeal carcinoma and lung cancer .
Cat. No.: HY-N17748
CAS No.: 1431563-56-2
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Cat. No.: HY-N21864
CAS No.: 1303438-53-0
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Flavonoids Flavonones Plants Moraceae Morus cathayana Hemsl.
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Cat. No.: HY-W727102
CAS No.: 180161-92-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
