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Results for "

ATF

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ATF6 (9) 11β-HSD (2) 5-HT Receptor (3) Akt (10) Aminoacyl-tRNA Synthetase (1) AMPK (2) Androgen Receptor (3) Antibiotic (2) Apoptosis (31) Atg8/LC3 (5) Autophagy (17) Bacterial (2) Bcl-2 Family (6) Biochemical Assay Reagents (1) Caspase (6) Ceramidase (1) ClpP (1) DAPK (3) DNA/RNA Synthesis (2) Drug Derivative (2) Endogenous Metabolite (9) Environmental Pollutants (2) Epigenetic Reader Domain (8) ERK (4) Estrogen Receptor/ERR (3) Eukaryotic Initiation Factor (eIF) (10) Ferroptosis (5) FOXO (3) G-quadruplex (2) Glutathione Peroxidase (2) HDAC (1) Heme Oxygenase (HO) (2) HIF/HIF Prolyl-Hydroxylase (1) Histone Methyltransferase (4) HSP (1) IFNAR (1) Interleukin Related (1) IRE1 (2) Isocitrate Dehydrogenase (IDH) (1) Isotope-Labeled Compounds (5) JAK (3) JNK (6) Keap1-Nrf2 (4) MDM-2/p53 (2) MEK (1) Melatonin Receptor (5) MetAP (1) Microtubule/Tubulin (1) Mitochondrial Metabolism (1) Mitophagy (5) mTOR (4) MyD88 (2) NF-κB (6) NO Synthase (2) Nuclear Hormone Receptor 4A/NR4A (2) Orphan GPCR (1) p38 MAPK (10) p62 (3) PANoptosis (1) Parasite (3) PARP (4) PD-1/PD-L1 (1) PERK (9) Phosphodiesterase (PDE) (2) PI3K (6) PKA (1) PKC (1) PROTACs (1) Protein Arginine Deiminase (1) Ras (1) Reactive Oxygen Species (ROS) (12) Reference Standards (13) Ribosomal S6 Kinase (RSK) (2) Sigma Receptor (1) Sirtuin (1) Small Interfering RNA (siRNA) (28) SOD (1) STAT (3) Stearoyl-CoA Desaturase (SCD) (3) STING (3) TGF-β Receptor (1) Thyroid Hormone Receptor (3) TNF Receptor (1) Toll-like Receptor (TLR) (5) VEGFR (2)
By Research Areas:	Cancer (54) Cardiovascular Disease (10) Endocrinology (6) Infection (8) Inflammation/Immunology (26) Metabolic Disease (18) Neurological Disease (25)
Oligonucleotides:	Rat Pre-designed siRNA Sets (8) Mouse Pre-designed siRNA Sets (9) Human Pre-designed siRNA Sets (11) siRNAs (28)

109

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: ATF6

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0075

Melatonin Maximum Cited Publications 137 Publications Verification N-Acetyl-5-methoxytryptamine	Melatonin Receptor Autophagy Mitophagy Endogenous Metabolite Apoptosis PANoptosis	Infection Neurological Disease Inflammation/Immunology Cancer
Melatonin is a hormone made by the pineal gland that can activate melatonin receptor and inhibit PANoptosis. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties . Melatonin is a novel selective *ATF-6* inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation . Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress .

HY-108434

Ceapin-A7 20+ Cited Publications	ATF6	Neurological Disease Metabolic Disease
Ceapin-A7 is a selective blocker of ATF6α signaling in response to ER stress, with an IC₅₀ of 0.59 μM. Ceapin-A7 can be used to explore both the mechanism of activation of ATF6α and its role in pathological settings .

HY-13241

Ralimetinib dimesylate 10+ Cited Publications LY2228820 dimesylate	p38 MAPK Autophagy Apoptosis	Inflammation/Immunology Cancer
Ralimetinib dimesylate (LY2228820 dimesylate) is a selective, ATP-competitive inhibitor of p38 MAPK α/β with IC₅₀s of 5.3 and 3.2 nM, respectively. Ralimetinib (LY2228820) selectively inhibits phosphorylation of MK2 (Thr334), with no effect on phosphorylation of p38a MAPK, JNK, ERK1/2, c-Jun, ATF2, or c-Myc.

HY-112680A

Carboxy pyridostatin trifluoroacetate salt 5 Publications Verification	G-quadruplex	Neurological Disease
Carboxy pyridostatin trifluoroacetate salt is a G-quadruplex ligand. Carboxy pyridostatin trifluoroacetate salt has a highly molecular specificity to RNA on DNA G4s and reduces *ATF-5* protein. Carboxy pyridostatin trifluoroacetate salt reduces cell proliferation and hinders stress granule (SG) formation .

HY-100355

C18-Ceramide (d18:1/18:0) C18-Ceramide	Endogenous Metabolite	Neurological Disease Cancer
C18-Ceramide (d18:1/18:0) is a bioactive molecule with multiple functions in cells, not a traditional agonist or inhibitor targeting a single site. It can act on multiple cellular targets, such as proteins related to endoplasmic reticulum stress (e.g., ATF-4, XBP-1, CHOP), proteins in the PI3K/AKT signaling pathway, and SNARE complex proteins. It exerts activities like inducing cell death, promoting autophagy, and regulating exocytosis through mechanisms such as activating endoplasmic reticulum stress, inhibiting the PI3K/AKT signaling pathway, and affecting lipid raft - related functions. It can be used in research on the mechanism of neuronal injury in the field of neuroscience and in the treatment research of cancers such as glioma in the field of oncology .

HY-152860

Darizmetinib HRX-0215	p38 MAPK JNK NF-κB MDM-2/p53	Cancer
Darizmetinib (HRX-0215) is an orally active, potent and selective inhibitor of mitogen-activated protein kinase kinase 4 (MKK4). Darizmetinib leads to enhancement of the MKK7 and JNK1 signaling pathways, thereby activating the transcription factors ATF2 and ELK1, promoting cell proliferation and liver regeneration. Darizmetinib is promising for research of preventing liver failure after extensive oncological liver resections or transplantation of small liver grafts .

HY-W050044

L-Azetidine-2-carboxylic acid 1 Publications Verification	Endogenous Metabolite PERK Atg8/LC3 Autophagy Bcl-2 Family Apoptosis Eukaryotic Initiation Factor (eIF) ATF6	Cardiovascular Disease Neurological Disease Metabolic Disease Endocrinology Cancer
L-Azetidine-2-carboxylic acid is a proline analog. L-Azetidine-2-carboxylic acid upregulates the lipid autophagy marker LC3-II via activation of the PERK pathway. L-Azetidine-2-carboxylic acid increases pro-apoptotic BAX protein. L-Azetidine-2-carboxylic acid induces *ATF6* cleavage and upregulates phosphorylated eIF2α levels. L-Azetidine-2-carboxylic acid induces ER stress, inducing protein misfolding and aggregation. L-Azetidine-2-carboxylic acid shows teratogenic, pro-inflammatory and pro-apoptotic effects .

HY-151923

ATF3 inducer 1 2 Publications Verification	Epigenetic Reader Domain	Metabolic Disease
ATF3 inducer 1 is a potent *ATF3* inducer. ATF3 inducer 1 increases the ATF3 protein and ATF3 mRNA expression. ATF3 inducer 1 shows anti-MetS activity in mouse .

HY-B1198

Piperonyl butoxide 1 Publications Verification ENT-14250	Environmental Pollutants Parasite	Infection Cancer
Piperonyl butoxide (ENT-14250) is a pesticide synergist and food additive. Piperonyl butoxide has adverse effects on reproduction, development and behavior in mice. Piperonyl butoxide can activate c-Jun and *ATF-2* in mouse hepatocytes. Piperonyl butoxide is a liver cancer carcinogen in rats and mice .

HY-B0075S

Melatonin-d4 N-Acetyl-5-methoxytryptamine-d₄	Isotope-Labeled Compounds Melatonin Receptor Autophagy Mitophagy Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Melatonin-d₄ is deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Antioxidative and anti-inflammatory properties . Melatonin is a selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation .

HY-12756A

E6446 dihydrochloride 5+ Cited Publications	Toll-like Receptor (TLR) Stearoyl-CoA Desaturase (SCD)	Metabolic Disease Inflammation/Immunology
E6446 dihydrochloride is a potent and orally acitve TLR7 and TLR9 antagonist, used in the research of deleterious inflammatory responses. E6446 dihydrochloride is also a potent SCD1 inhibitor (KD: 4.61 μM), significantly inhibiting adipogenic differentiation and hepatic lipogenesis through SCD1-ATF3 signaling. E6446 dihydrochloride also improves liver pathology in high-fat diet (HFD)-fed mice and may be useful in the study of non-alcoholic fatty liver disease (NAFLD) .

HY-124293

AA147 4 Publications Verification	ATF6 Reactive Oxygen Species (ROS)	Neurological Disease Metabolic Disease
AA147 is a endoplasmic reticulum (ER) proteostasis regulator. AA147 promotes protection against oxidative damage in neuronal cells and prevents endothelial barrier dysfunction by activating *ATF6* arm (selectively) of the unfolded protein response (UPR) and the NRF2 oxidative stress response. AA147 can rebalances XBP1s expression in vivo, and also induces survival motor neuron (SMN) expression and spinal motorneuron (MN) protection .

HY-175032

ATF3-IN-1	Ferroptosis Epigenetic Reader Domain Reactive Oxygen Species (ROS) Glutathione Peroxidase	Cardiovascular Disease Neurological Disease
ATF3-IN-1 is a ferroptosis and *ATF3* inhibitor. ATF3-IN-1 inhibits oxidative stress and ferroptosis through the ATF3/SLC7A11/GPX4 pathway, exerting anti-ischemic stroke effects. ATF3-IN-1 can attenuate ischemia/reperfusion (I/R) injury and improve neuronal survival. ATF3-IN-1 has neuroprotective effects and can be used to study ischemic stroke .

HY-160196

HC-7366 GCN2 modulator-1	Eukaryotic Initiation Factor (eIF)	Cancer
HC-7366 (GCN2 modulator-1) is an orally effective GCN2 activator. HC-7366 can effectively compete and occupy the ATP binding pocket of GCN2, with its IC₅₀ being 72 nM. This binding triggers the conformational activation of GCN2, leading to the upregulation of downstream signals (such as *ATF4, ASNS) in the integrated stress response (ISR) pathway, ultimately exerting anti-tumor effects. HC-7366 also has inhibitory activity against ZAK, with its IC₅₀* being 47 nM. HC-7366 can be used for research on fibrosarcoma and acute myeloid leukemia .

HY-158202

ATF4-IN-2	Epigenetic Reader Domain	Neurological Disease
ATF4-IN-2 (Compound 29) is a *ATF4* inhibitor with a IC₅₀ value of 47.71 nM. ATF4-IN-2 can be used in the study of neurodegenerative diseases .

HY-12756

E6446 5+ Cited Publications	Toll-like Receptor (TLR) Stearoyl-CoA Desaturase (SCD)	Metabolic Disease Inflammation/Immunology
E6446 is a potent and orally acitve TLR7 and TLR9 antagonist, used in the research of deleterious inflammatory responses. E6446 is also a potent SCD1 inhibitor (KD: 4.61 μM), significantly inhibiting adipogenic differentiation and hepatic lipogenesis through SCD1-ATF3 signaling. E6446 also improves liver pathology in high-fat diet (HFD)-fed mice and may be useful in the study of non-alcoholic fatty liver disease (NAFLD) .

HY-B0075S1

Melatonin-d3 N-Acetyl-5-methoxytryptamine-d₃	Isotope-Labeled Compounds Melatonin Receptor Autophagy Mitophagy Endogenous Metabolite Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Melatonin-d₃ is the deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties . Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation . Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress .

HY-123581

Quinocetone 1 Publications Verification	Antibiotic Bacterial ATF6 DAPK Autophagy NF-κB NO Synthase Apoptosis Reactive Oxygen Species (ROS) Keap1-Nrf2 Heme Oxygenase (HO)	Infection Inflammation/Immunology
Quinocetone is an orally active animal feed additive used to increase the meat production of livestock and poultry. Quinocetone exhibits antibacterial activity against a variety of pathogenic microorganisms. Quinocetone exhibits tissue-specific (liver, lymphocyte) toxicity. Quinocetone induces autophagy in cells through the *ATF6/DAPK1* pathway. Quinocetone activates the NF-κB and iNOS pathways, leading to cell apoptosis, hepatocyte vacuolar degeneration and fibrosis. Quinocetone can inhibit Nrf2/HO-1 and induce the generation of reactive oxygen species (ROS), leading to oxidative stress and DNA damage .

HY-158201

ATF4-IN-1	Eukaryotic Initiation Factor (eIF)	Neurological Disease
ATF4-IN-1 (Compound 21) is an *ATF4* inhibitor and also an eIF2B activator. ATF4-IN-1 can be used in research on neurodegenerative diseases .

HY-147831

HR-19011	Eukaryotic Initiation Factor (eIF) Epigenetic Reader Domain	Cancer
HR-19011 is an eIF2α phosphorylation activator targeting heme-regulated inhibitor HRI (EIF2AK1). HR-19011 exhibits growth inhibitory activity against K562 cells with an IC₅₀ value of 3.91 µM. HR-19011 inhibits the growth of hematologic malignancies by targeting HRI to activate the integrated stress response via the HRI-eIF2α-ATF4 axis. HR-19011 shows good safety in vivo. HR-19011 can be used for research on hematologic malignancies (leukemia) .

HY-B0075R

Melatonin (standard) Maximum Cited Publications 137 Publications Verification N-Acetyl-5-methoxytryptamine (standard); Melatonin	Reference Standards Melatonin Receptor Autophagy Mitophagy Endogenous Metabolite Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Melatonin (Standard) is the analytical standard of Melatonin. This product is intended for research and analytical applications. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties . Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation . Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress .

HY-132182

HPA-12 1 Publications Verification	Ceramidase Autophagy Apoptosis ATF6	Neurological Disease Cancer
HPA-12 is a blood-brain barrier-permeable small-molecule inhibitor of ceramide transfer protein (CERT) with four stereoisomers (the (1R,3R)-stereoisomer exhibits the highest activity). HPA-12 blocks the transport of ceramide from the endoplasmic reticulum to the Golgi apparatus by binding to the START domain of CERT, leading to intracellular ceramide accumulation and inhibition of sphingomyelin (SM) synthesis. HPA-12 induces endoplasmic reticulum stress via the *GRP78/ATF6/CHOP* axis and activates mitochondrial autophagy, thereby inhibiting cell growth and inducing apoptosis. In in vivo experiments, HPA-12 significantly reduces the leukemia burden and splenomegaly in mouse models of acute myeloid leukemia (AML) and prolongs survival. HPA-12 is applicable for the research of lipid metabolism in acute myeloid leukemia and Alzheimer's disease .

HY-103100

SB-699551 1 Publications Verification	5-HT Receptor Epigenetic Reader Domain Akt Ribosomal S6 Kinase (RSK) FOXO	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
SB-699551 is a selective and brain penetrant 5-HT5A receptor antagonist with a pK_i of 8.2 nM. SB-699551 shows high selectivity over most other 5-HT receptor subtypes, dopamine receptors, and α1B adrenoceptor. SB-699551 disrupts Gαi/o-coupled and PI3K/AKT/mTOR signaling pathways, alters CREB, ATF1, AKT, PRAS40, S6K, and FOXO1 phosphorylation in breast tumor cells. SB-699551 can be used for the research of anxiety, breast cancer, and Alzheimer's disease .

HY-112056

DIM-C-pPhCO2Me 1 Publications Verification	Nuclear Hormone Receptor 4A/NR4A Apoptosis DAPK Isocitrate Dehydrogenase (IDH) PERK	Cancer
DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1) antagonist. DIM-C-pPhCO2Me induces Apoptosis. DIM-C-pPhCO2Me decreases PAX3-FOXO1A, N-Myc, Rassf4, MyoD1, Grem1, and DAPK1 proteins. DIM-C-pPhCO2Me decreases expression of TXNDC5 and IDH1, induces markers of ER stress (CHOP, *ATF4* and p-PERK). DIM-C-pPhCO2Me inhibits renal cell carcinoma, breast cancer. DIM-C-pPhCO2Me can also be used in rhabdomyosarcoma research .

HY-112680

Carboxypyridostatin	G-quadruplex	Neurological Disease
Carboxypyridostatin is a G-quadruplex ligand. Carboxypyridostatin has a highly molecular specificity to RNA on DNA G4s and reduces *ATF-5* protein. Carboxypyridostatin reduces cell proliferation and hinders stress granule (SG) formation .

HY-108618

BC11-38 2 Publications Verification	Phosphodiesterase (PDE)	Endocrinology
BC11-38 is a potent, selective, and biologically active PDE11 inhibitor, with IC₅₀s of 0.28 µM and >100 µM for PDE11 and PDE1-10, respectively. BC11-38 elevates cAMP levels, PKA-mediated ATF-1 phosphorylation, and cortisol production in H295R cells .

HY-170872

PT-129	PROTACs DNA/RNA Synthesis	Cancer
PT-129 is a G3BP1/G3BP2 PROTAC degrader. PT-129 inhibits the formation of stress granules, disassembles pre-existing stress granules, disrupts stress granule-mediated *ATF4* trafficking via migratory exocytosis, and suppresses cancer cell proliferation. PT-129 is applicable to the research of lung cancer and melanoma .

HY-163319

NCA029	ClpP Apoptosis	Cancer
NCA029 is a potent and selective homo sapiens caseinolytic protease P (HsClpP) activator with an EC₅₀ of 0.15 μM. NCA029 acts on HsClpP to activate an ATF3-dependent integrative stress response, leading to colon cancer cell death .

HY-B0075S2

Melatonin-d7 N-Acetyl-5-methoxytryptamine-d₇	Isotope-Labeled Compounds Melatonin Receptor Autophagy Mitophagy Endogenous Metabolite Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Melatonin-d₇ is the deuterium labeled Melatonin (HY-B0075). Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties . Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation . Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress .

HY-153340

I-152	Keap1-Nrf2	Metabolic Disease
I-152 is a conjugate containing N-acetyl-cysteine (NAC) and cysteamine (MEA). I-152 activates NRF2 and *ATF4* signals. I-152 has anti-proliferative properties .

HY-153339

E235	Eukaryotic Initiation Factor (eIF)	Cancer
E235 is an expression regulator of activates transcription factor 4 (ATF4). E235 reduces cell viability by activating integrated stress response (ISR) and DNA damage response signals. E235 has anti-proliferative activity and can be used for tumor research .

HY-RS01129

ATF3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ATF3 Human Pre-designed siRNA Set A contains three designed siRNAs for ATF3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ATF3 Human Pre-designed siRNA Set A ATF3 Human Pre-designed siRNA Set A

HY-134963

SBI-0087702	PKC	Cancer
SBI-0087702 promots the cytoplasmic localization of *ATF2* in melanoma cells. SBI-0087702-induced translocation of ATF2 to the mitochondria results in increased apoptosis due to loss of mitochondrial membrane integrity. SBI-0087702 also inhibits growth and motility of melanoma cells. SBI-0087702 was shown to inhibit ATF2 phosphorylation on Thr52 by PKCε .

HY-158203

BMP agonist 2	TGF-β Receptor	Others
BMP agonist 2 (derivative I-9) is a potent bone-inducing cytokine. BMP agonist 2 promotes bone tissue production by increasing the proportion and activity of osteoblasts. BMP agonist 2 promotes osteoblast proliferation and differentiation through the *BMP2-ATF4* signaling axis, in which ATF4 is a transcription factor closely related to osteoblast differentiation and bone formation. BMP agonist 2 can be used in the study of senile osteoporosis (SOP) .

HY-W020952

Palladium(Ⅱ) acetylacetonate Palladium(Ⅱ) 2,4-pentanedionate; Pd(acac)2	Biochemical Assay Reagents HSP Eukaryotic Initiation Factor (eIF) IRE1 JNK Apoptosis	Cancer
Palladium(II) acetylacetonate is a metal-organic complex. Palladium(II) acetylacetonate upregulates the expression of GRP78, *ATF-4, XBP-1, CHOP, and phosphorylated c-Jun. Palladium(II) acetylacetonate induces Apoptosis*. Palladium(II) acetylacetonate has anticancer effects against non-small cell lung cancer, gastric cancer, leukemia, and cervical cancer .

HY-117938

T-3861174	Aminoacyl-tRNA Synthetase	Cancer
T-3861174 is an inhibitor of prolyl-tRNA synthetase (PRS, Aminoacyl-tRNA Synthetase) without completely inhibiting its translation process. T-3861174 activates the *GCN2-ATF4* pathway and induces death in multiple tumor cell lines, including SK-MEL-2. T-3861174 demonstrated significant antitumor activity in multiple xenograft models without significantly affecting body weight .

HY-158196

PERK/eIF2α activator 1	PERK Apoptosis	Cancer
PERK/eIF2α activator 1 (compound V8) is a flavonoid with an anti-tumor activity. PERK/eIF2α activator 1 induces apoptosis and activates the PERK-eIF2α-ATF4 pathway. PERK/eIF2α activator 1 inhibits HepG2 cell proliferation with an IC₅₀ value of 23 μM .

HY-121337

Flurochloridone R-40244	Environmental Pollutants Apoptosis Bcl-2 Family	Others
Flurochloridone (R-40244) is a selective preemergence and persistent herbicide. Flurochloridone induces endoplasmic reticulum (ER) stress and activated unfolded protein response (UPR) signaling pathways. Flurochloridone impairs cell viability and induces cytotoxicity and apoptosis mediated by ER stress via activating *eIF2α-ATF4/ATF6-CHOP-Bim/Bax* signaling pathways in TM4 cells .

HY-162384

EPIC-0628	Histone Methyltransferase	Cancer
EPIC-0628 is an inhibitor of the HOTAIR-EZH2 interaction and promotes *ATF3* expression. The long noncoding RNA HOTAIR has been found to regulate glioblastoma (GBM) progression and mediate DNA damage repair (DDR) by interacting with the catalytic subunit EZH2 of PRC2. EPIC-0628 also inhibits the ATF3-p38-E2F1 DDR pathway to inhibit the HR pathway and upregulates CDKN1A (p21) expression, causing cell cycle arrest. EPIC-0628 also synergizes with Temozolomide (TMZ) (HY-17364) to enhance its in vivo potency .

HY-112903A

YW3-56 hydrochloride	Protein Arginine Deiminase MDM-2/p53 PERK mTOR Autophagy	Cancer
YW3-56 (hydrochloride) is a PAD inhibitor. YW3-56 (hydrochloride) activates p53 target genes. YW3-56 (hydrochloride) activates *ATF* and blocks autophagy flux. YW3-56 induces ER stress through the *PERK-eIF2α-ATF4* signaling cascade and inhibits the mTOR signaling. YW3-56 (hydrochloride) inhibits triple-negative breast cancer .

HY-RS01130

ATF4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ATF4 Human Pre-designed siRNA Set A contains three designed siRNAs for ATF4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ATF4 Human Pre-designed siRNA Set A ATF4 Human Pre-designed siRNA Set A

HY-RS10647

PLAU Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PLAU Human Pre-designed siRNA Set A contains three designed siRNAs for PLAU gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PLAU Human Pre-designed siRNA Set A PLAU Human Pre-designed siRNA Set A

HY-B1198R

Piperonyl butoxide (Standard) ENT-14250 (Standard)	Parasite Reference Standards	Infection Cancer
Piperonyl butoxide (Standard) is the analytical standard of Piperonyl butoxide. This product is intended for research and analytical applications. Piperonyl butoxide (ENT-14250) is a pesticide synergist and food additive. Piperonyl butoxide has adverse effects on reproduction, development and behavior in mice. Piperonyl butoxide can activate c-Jun and *ATF-2* in mouse hepatocytes. Piperonyl butoxide is a liver cancer carcinogen in rats and mice .

HY-158104

LPPM-8	ATF6	Others
LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .

HY-162886

BSO-07	JNK Reactive Oxygen Species (ROS)	Cancer
BSO-07 is a ROS/JNK activator with significant anticancer effects, having an IC₅₀ value of 24.81 μM against human breast cancer (BC) cells. BSO-07 induces apoptosis (Apoptosis) and paraptosis by activating JNK and increasing ROS levels, including enhancing the expression of apoptosis-associated proteins such as PARP, Bax, phosphorylated p53, ATF4, and CHOP, while decreasing the levels of anti-apoptotic proteins like Bcl-2, Bcl-xL, and Survivin. BSO-07 holds promise for research in the field of breast cancer .

HY-121033

BS148	Sigma Receptor p38 MAPK Apoptosis	Cancer
BS148 is a selective sigma-2 receptor (S2R) agonist with a K_i 20 nM. BS148 shows >80-fold selective for S2R than S1R. BS148 activates the endoplasmic reticulum stress response through the upregulation of protein kinase R-like ER kinase (PERK), activating transcription factor 4 (ATF4) genes, and C/EBP homologous protein (CHOP). BS148 induces apoptosis in melanoma cell. BS148 downregulates genes related to the cholesterol pathway and activates the MAPK signaling pathway. BS148 can be used for the study of melanoma .

HY-W050044R

L-Azetidine-2-carboxylic acid (Standard)	Reference Standards Endogenous Metabolite PERK Atg8/LC3 Autophagy Bcl-2 Family Apoptosis Eukaryotic Initiation Factor (eIF) ATF6	Cardiovascular Disease Neurological Disease Metabolic Disease Endocrinology Cancer
L-Azetidine-2-carboxylic acid is a proline analog. L-Azetidine-2-carboxylic acid upregulates the lipid autophagy marker LC3-II via activation of the PERK pathway. L-Azetidine-2-carboxylic acid increases pro-apoptotic BAX protein. L-Azetidine-2-carboxylic acid induces ATF6 cleavage and upregulates phosphorylated eIF2α levels. L-Azetidine-2-carboxylic acid induces ER stress, inducing protein misfolding and aggregation. L-Azetidine-2-carboxylic acid shows teratogenic, pro-inflammatory and pro-apoptotic effects .

HY-13559A

Atiprimod dimaleate Azaspirane dimaleate; SKF 106615-12 dimaleate; SKF 106615A12 dimaleate	STAT Apoptosis Caspase Interleukin Related Autophagy Reactive Oxygen Species (ROS) Atg8/LC3 p62 JAK	Cardiovascular Disease Inflammation/Immunology Cancer
Atiprimod (Azaspirane) (dimaleate) is a STAT3 inhibitor with antitumor, anti-inflammatory, and anti-angiogenic activities. Atiprimod blocks the signaling pathways of IL-6 and VEGF by inhibiting the phosphorylation of signal transducer and activator of STAT3. Atiprimod blocks the JAK-STAT signaling pathway by inhibiting the phosphorylation of JAK2 and JAK3. Atiprimod also inhibits cell proliferation, induces cell cycle arrest, and induces autophagy and apoptosis. Atiprimod triggers persistent ER stress-mediated apoptosis in breast cancer cells by activating the *PERK/eIF2α/ATF4/CHOP* axis and inhibiting the nuclear translocation of STAT3/NF-κB. Atiprimod shows great anti-tumor activities in tumor xenograft mouse models. Atiprimod can be used for the study of pituitary adenoma, breast cancer, multiple myeloma and acute myeloid leukemia (AML) .

HY-RS01132

ATF6 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ATF6 Human Pre-designed siRNA Set A contains three designed siRNAs for ATF6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ATF6 Human Pre-designed siRNA Set A ATF6 Human Pre-designed siRNA Set A

HY-RS01133

Atf6 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Atf6 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Atf6 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Atf6 Mouse Pre-designed siRNA Set A Atf6 Mouse Pre-designed siRNA Set A

Cat. No.	Product Name

HY-L054

Endoplasmic Reticulum Stress Compound Library

356 compounds

Endoplasmic reticulum (ER) contributes to the production and folding of approximately one third of cellular proteins, and is thus inextricably linked to the maintenance of cellular homeostasis and the fine balance between health and disease. However, some adverse factors negatively impact ER functions and protein synthesis, resulting in the activation of Endoplasmic reticulum stress (ER stress, ERS) and unfolded protein response (UPR) signaling pathways. The UPR is triggered when ER protein folding capacity is overwhelmed by cellular demand and the UPR initially aims to restore ER homeostasis and normal cellular functions. However, if this fails, then the UPR triggers cell death. Chronic ER stress and defects in UPR signaling are emerging as key contributors to a growing list of human diseases, including diabetes, neurodegeneration and cancer.

MCE Endoplasmic Reticulum Stress Compound Library contains 356 ER stress-related compounds that mainly target PERK, IRE1, ATF6, etc. MCE ER stress library is a useful tool for researching ER stress and related diseases.

HY-L090

Transcription Factor-Targeted Library

2,383 compounds

Transcription is the essential first step in the conversion of the genetic information in the DNA into protein and the major point at which gene expression is controlled. Transcription of protein-coding genes is accomplished by the multi-subunit enzyme RNA polymerase II and an ensemble of ancillary proteins, called transcription factors (TFs). Transcription factors play an important role in the long-term regulation of cell growth, differentiation and responses to environmental cues. Deregulated transcription factors contribute to the pathogenesis of a plethora of human diseases, ranging from diabetes, inflammatory disorders and cardiovascular disease to many cancers, and thus these proteins hold great therapeutic potential.

MCE offers a unique collection of 2,383 compounds with validated transcription factor targets modulating properties. MCE transcription factor-targeted compound library is an effective tool for researching transcription factors as drug targets as well as modulation of TFs for different therapeutic applications.

Cat. No.	Product Name	Type

HY-W011927

4,4'-Sulfonyldiphenol

Bisphenol S; Bis(4-hydroxyphenyl) sulfone

Biochemical Assay Reagents

4,4'-Sulfonyldiphenol (Bisphenol S; Bis(4-hydroxyphenyl) sulfone), a substitute for Bisphenol A (HY-18260), is widely used in industrial and consumer products. 4,4'-Sulfonyldiphenol is an oally ative estrogen receptor (ER) agonist and can competitively bind to thyroid hormone receptors (TR) with IC₅₀ values for TRα and TRβ are 2650 μM and 2294 μM respectively, thereby affecting breast development and reducing the expression of androgen receptor (AR) in fetal testes. 4,4'-Sulfonyldiphenol promotes the progression of glioblastoma by upregulating the EZH2 mediated PI3K/AKT/mTOR pathway. Under chronic exposure, 4,4'-Sulfonyldiphenol can cause significant lipid deposition and dyslipidemia in the mouse liver by upregulating JunB and Atf3, and has a role in causing obesity at low doses. 4,4'-Sulfonyldiphenol induces intestinal inflammation by altering the intestinal microbiome. 4,4'-Sulfonyldiphenol accelerates the progression of atherosclerosis in zebrafish embryo larvae .

HY-W020952

Palladium(Ⅱ) acetylacetonate Palladium(Ⅱ) 2,4-pentanedionate; Pd(acac)2	Biochemical Assay Reagents
Palladium(II) acetylacetonate is a metal-organic complex. Palladium(II) acetylacetonate upregulates the expression of GRP78, *ATF-4, XBP-1, CHOP, and phosphorylated c-Jun. Palladium(II) acetylacetonate induces Apoptosis*. Palladium(II) acetylacetonate has anticancer effects against non-small cell lung cancer, gastric cancer, leukemia, and cervical cancer .

HY-W011927R

4,4'-Sulfonyldiphenol (Standard)

Bisphenol S (Standard); Bis(4-hydroxyphenyl) sulfone (Standard)

Biochemical Assay Reagents

4,4'-Sulfonyldiphenol (Bisphenol S; Bis(4-hydroxyphenyl) sulfone) (Standard) is the analytical standard of 4,4'-Sulfonyldiphenol (HY-W011927). This product is intended for research and analytical applications. 4,4'-Sulfonyldiphenol, a substitute for Bisphenol A (HY-18260), is widely used in industrial and consumer products. 4,4'-Sulfonyldiphenol is an estrogen receptor (ER) agonist and can competitively bind to thyroid hormone receptors (TR) with IC₅₀ values for TRα and TRβ are 2650 μM and 2294 μM respectively, thereby affecting breast development and reducing the expression of androgen receptor (AR) in fetal testes. 4,4'-Sulfonyldiphenol promotes the progression of glioblastoma by upregulating the EZH2 mediated PI3K/AKT/mTOR pathway. Under chronic exposure, 4,4'-Sulfonyldiphenol can cause significant lipid deposition and dyslipidemia in the mouse liver by upregulating JunB and Atf3, and has a role in causing obesity at low doses. 4,4'-Sulfonyldiphenol induces intestinal inflammation by altering the intestinal microbiome. 4,4'-Sulfonyldiphenol accelerates the progression of atherosclerosis in zebrafish embryo larvae.

Cat. No.	Product Name	Target	Research Area

HY-158104

LPPM-8	ATF6	Others
LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .

HY-P5762A

Phoenixin-14 TFA PNX-14 TFA	Orphan GPCR Glutathione Peroxidase Ferroptosis ERK Toll-like Receptor (TLR) Sirtuin FOXO Akt PKA MyD88 Reactive Oxygen Species (ROS) Apoptosis NF-κB	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology
Phoenixin-14 (PNX-14) TFA is an endogenous neuropeptide with multiple biological activities, and serves as the endogenous ligand of GPR173. Phoenixin-14 TFA reduces ROS production by inhibiting the HMGB1/TLR4/MyD88/NF-κB signaling axis, thereby exerting antioxidant and mitochondrial protective effects. Phoenixin-14 TFA inhibits FOXO3 phosphorylation by upregulating SIRT3 expression, suppresses apoptosis, and improves myocardial systolic/diastolic function. Phoenixin-14 TFA resists ferroptosis by activating the *ATF4/SLC7A11/GPX4* axis; it activates ERK1/2 phosphorylation via GPR173. Phoenixin-14 TFA can be used in researches on neuroprotection, diabetes, cardiomyopathy, reproductive protection and so on .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0075

Melatonin Maximum Cited Publications 137 Publications Verification N-Acetyl-5-methoxytryptamine	Structural Classification Natural Products Other disease Neurological Disease Classification of Application Fields Anti-aging Disease markers Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification Cancer	Melatonin Receptor Autophagy Mitophagy Endogenous Metabolite Apoptosis PANoptosis
Melatonin is a hormone made by the pineal gland that can activate melatonin receptor and inhibit PANoptosis. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties . Melatonin is a novel selective *ATF-6* inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation . Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress .

HY-100355

C18-Ceramide (d18:1/18:0) C18-Ceramide	Structural Classification Alkaloids Neurological Disease Classification of Application Fields Other Alkaloids Endogenous metabolite Disease Research Fields Source Classification Cancer	Endogenous Metabolite
C18-Ceramide (d18:1/18:0) is a bioactive molecule with multiple functions in cells, not a traditional agonist or inhibitor targeting a single site. It can act on multiple cellular targets, such as proteins related to endoplasmic reticulum stress (e.g., ATF-4, XBP-1, CHOP), proteins in the PI3K/AKT signaling pathway, and SNARE complex proteins. It exerts activities like inducing cell death, promoting autophagy, and regulating exocytosis through mechanisms such as activating endoplasmic reticulum stress, inhibiting the PI3K/AKT signaling pathway, and affecting lipid raft - related functions. It can be used in research on the mechanism of neuronal injury in the field of neuroscience and in the treatment research of cancers such as glioma in the field of oncology .

HY-W050044

L-Azetidine-2-carboxylic acid 1 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite PERK Atg8/LC3 Autophagy Bcl-2 Family Apoptosis Eukaryotic Initiation Factor (eIF) ATF6
L-Azetidine-2-carboxylic acid is a proline analog. L-Azetidine-2-carboxylic acid upregulates the lipid autophagy marker LC3-II via activation of the PERK pathway. L-Azetidine-2-carboxylic acid increases pro-apoptotic BAX protein. L-Azetidine-2-carboxylic acid induces *ATF6* cleavage and upregulates phosphorylated eIF2α levels. L-Azetidine-2-carboxylic acid induces ER stress, inducing protein misfolding and aggregation. L-Azetidine-2-carboxylic acid shows teratogenic, pro-inflammatory and pro-apoptotic effects .

HY-N0660

Jujuboside B	Cardiovascular Disease Triterpenes Structural Classification other families Classification of Application Fields Terpenoids Plants Disease Research Fields Source Classification	Apoptosis PARP Caspase AMPK Autophagy VEGFR Keap1-Nrf2 STING 11β-HSD Ferroptosis PI3K Akt p38 MAPK ERK
Jujuboside B is a bioactive saponin component isolated from Ziziphi Spinosae Semen (sour jujube seed), with oral efficacy and blood-brain barrier permeability. Jujuboside B induces acute leukemia cell death and drives necroptosis apoptosis by activating the RIPK1/RIPK3/MLKL pathway. Jujuboside B upregulates the expression of NOXA, PARP and caspase-3, activates AMPK, inhibits the proliferation of breast cancer cells, and induces cell apoptosis and autophagy. Jujuboside B inhibits angiogenesis and tumor growth by blocking the VEGFR-2 signaling pathway. Jujuboside B alleviates liver injury in mice by regulating the Nrf2-STING signaling pathway . Jujuboside B alleviates liver injury by regulating anti-inflammatory responses and downregulating the expression of 11β-HSD2. Jujuboside B induces ferroptosis and overcomes radioresistance in non-small cell lung cancer via the PPARγ-ATF3-Gpx4 signaling pathway. Jujuboside B exerts inhibitory effects on platelet aggregation. Jujuboside B inhibits febrile seizures by suppressing the activity of AMPA receptors. Jujuboside B reverses chronic unpredictable mild stress-promoted tumor progression by blocking the PI3K/Akt and MAPK/ERK pathways and dephosphorylating CREB signaling. Jujuboside B is applicable to related studies on acute leukemia, breast cancer, PM_2.5-induced lung injury, hepatotoxicity, liver injury, colorectal cancer, non-small cell lung cancer, thromboembolic diseases, cardiovascular diseases associated with high platelet aggregation, febrile seizures, and depressive-like phenotypes .

HY-B0075R

Melatonin (standard) Maximum Cited Publications 137 Publications Verification N-Acetyl-5-methoxytryptamine (standard); Melatonin	Structural Classification Natural Products Microorganisms Other disease Disease markers Endogenous metabolite Source Classification	Reference Standards Melatonin Receptor Autophagy Mitophagy Endogenous Metabolite Apoptosis
Melatonin (Standard) is the analytical standard of Melatonin. This product is intended for research and analytical applications. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties . Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation . Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress .

HY-W050044R

L-Azetidine-2-carboxylic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite PERK Atg8/LC3 Autophagy Bcl-2 Family Apoptosis Eukaryotic Initiation Factor (eIF) ATF6
L-Azetidine-2-carboxylic acid is a proline analog. L-Azetidine-2-carboxylic acid upregulates the lipid autophagy marker LC3-II via activation of the PERK pathway. L-Azetidine-2-carboxylic acid increases pro-apoptotic BAX protein. L-Azetidine-2-carboxylic acid induces ATF6 cleavage and upregulates phosphorylated eIF2α levels. L-Azetidine-2-carboxylic acid induces ER stress, inducing protein misfolding and aggregation. L-Azetidine-2-carboxylic acid shows teratogenic, pro-inflammatory and pro-apoptotic effects .

HY-N12887

Mycothiazole	Natural Products Marine natural products Sponge Source Classification	Mitochondrial Metabolism
Mycothiazole is an inhibitor for mitochondrial electron transport chain (ETC) complex I. Mycothiazole exhibits cytotoxicity in cancer cells Huh7 (IC₅₀ is 55.8 μM), U87 and MCF7. Mycothiazole induces apoptosis in Huh7. Mycothiazole utilizes the unfolded protein response (UPR) and heat shock response (HSR) pathway involved transcription factors ATFS-1 and HSF1, to extend the lifespan of C. elegans .

HY-113027R

p-Hydroxymandelic acid (Standard)	Structural Classification Monophenols Ketones, Aldehydes, Acids Phenols Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Melatonin (Standard) is the analytical standard of Melatonin. This product is intended for research and analytical applications. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties . Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation . Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress .

HY-123647

Satratoxin H	Structural Classification Natural Products Microorganisms Source Classification	Endogenous Metabolite p38 MAPK JNK Caspase PARP ERK Apoptosis Reactive Oxygen Species (ROS)
Satratoxin H is a toxic metabolite of Stachybotrys atra. Satratoxin H induces caspase-3 and PARP cleavage via p38 MAPK and JNK pathways, stimulates JNK, ERK, and p38 MAPK phosphorylation, and activates JNK and p38 MAPK in a glutathione-sensitive manner. Satratoxin H induces DNA double-stranded breaks, apoptotic body formation, intracellular reactive oxygen species generation, and endoplasmic reticulum stress via *ATF6, PERK, and IRE1* pathways. Satratoxin H can be used for the research of central nervous system disorders and melanoma .

HY-W097625R

6-Methoxyflavone (Standard)	Structural Classification Flavonoids Flavones Thymelaeaceae Plants Pimelea simplex F.Muell. Source Classification	Toll-like Receptor (TLR) MyD88 p38 MAPK NF-κB Heme Oxygenase (HO) Reference Standards PERK
6-Methoxyflavone (Standard) is the analytical standard of 6-Methoxyflavone (HY-W097625). This product is intended for research and analytical applications. 6-Methoxyflavone is an orally active methoxyflavone. 6-Methoxyflavone suppresses neuroinflammation in microglia through the inhibition of TLR4/MyD88/p38 MAPK/NF-κB dependent pathways and the activation of HO-1/NQO-1 signaling. 6-Methoxyflavone induces S-phase arrest through the CCNA2/CDK2/p21CIP1 signaling pathway and activates the PERK/EIF2a/ATF4/CHOP pathway in HeLa cells. 6-Methoxyflavone acts as a Flumazenil (HY-B0009)-insensitive positive allosteric modulator at human recombinant α1β2γ2L and α2β2γ2L GABAα receptors. 6-Methoxyflavone inhibits NFAT Translocation into the nucleus and suppresses T cell activation. 6-Methoxyflavone partially restores chronic ethanol-induced behavioral deficits in mice. 6-Methoxyflavone antagonizes chronic constriction injury and diabetes associated neuropathic nociception expression. 6-Methoxyflavone can be used for the study of cancer, inflammation and neurological diseases .

HY-N0660R

Jujuboside B (Standard)	Triterpenes Structural Classification other families Terpenoids Plants Source Classification	Reference Standards ERK p38 MAPK Akt PI3K 11β-HSD STING VEGFR Ferroptosis Autophagy Apoptosis Keap1-Nrf2 Caspase PARP AMPK
Jujuboside B (Standard) is the analytical standard of Jujuboside B. This product is intended for research and analytical applications. Jujuboside B is a bioactive saponin component isolated from Ziziphi Spinosae Semen (sour jujube seed), with oral efficacy and blood-brain barrier permeability. Jujuboside B induces acute leukemia cell death and drives necroptosis apoptosis by activating the RIPK1/RIPK3/MLKL pathway. Jujuboside B upregulates the expression of NOXA, PARP and caspase-3, activates AMPK, inhibits the proliferation of breast cancer cells, and induces cell apoptosis and autophagy. Jujuboside B inhibits angiogenesis and tumor growth by blocking the VEGFR-2 signaling pathway. Jujuboside B alleviates liver injury in mice by regulating the Nrf2-STING signaling pathway . Jujuboside B alleviates liver injury by regulating anti-inflammatory responses and downregulating the expression of 11β-HSD2. Jujuboside B induces ferroptosis and overcomes radioresistance in non-small cell lung cancer via the PPARγ-ATF3-Gpx4 signaling pathway. Jujuboside B exerts inhibitory effects on platelet aggregation. Jujuboside B inhibits febrile seizures by suppressing the activity of AMPA receptors. Jujuboside B reverses chronic unpredictable mild stress-promoted tumor progression by blocking the PI3K/Akt and MAPK/ERK pathways and dephosphorylating CREB signaling. Jujuboside B is applicable to related studies on acute leukemia, breast cancer, PM_2.5-induced lung injury, hepatotoxicity, liver injury, colorectal cancer, non-small cell lung cancer, thromboembolic diseases, cardiovascular diseases associated with high platelet aggregation, febrile seizures, and depressive-like phenotypes.

Species:	Human (9) Rat (2) Mouse (4) Cynomolgus (1) Canine (1)
Tag:	His (12) Tag Free (4) Avi (3) GST (1) Fc (1)
Source:	HEK293 (9) CHO (1) Sf9 insect cells (2) E. coli (5)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P704369

	GDNF Protein, Human (134a.a, HEK293) Glial cell line-derived neurotrophic factor; ATF; HFB1-GDNF; HGDNF; HSCR3	Human	HEK293
	GDNF Protein, Human (134a.a, HEK293) is the recombinant human-derived GDNF protein, expressed by HEK293, with tag free tag.

HY-P700811

	PLAU/uPA Protein, Cynomolgus (HEK293, His) PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD	Cynomolgus	HEK293
	PLAU, also known as uPA (urokinase plasminogen activator), exhibits defects in conserved residues critical for propagation feature annotation. This defect in the PLAU/uPA protein prevents the propagation of specific functional characteristics associated with this protein. PLAU/uPA Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived PLAU/uPA protein, expressed by HEK293 , with C-His labeled tag.

HY-P78017

	PLAU/uPA Protein, Mouse (HEK293, C-His-Avi) 1 Publications Verification PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD	Mouse	HEK293
	PLAU or urokinase-type plasminogen activator (uPA) critically initiates fibrinolysis by cleaving plasminogen to form active plasmin.This enzymatic conversion is critical for regulating clot dissolution and tissue remodeling.PLAU/uPA Protein, Mouse (HEK293, C-His-Avi) is the recombinant mouse-derived PLAU/uPA protein, expressed by HEK293 , with C-His-Avi labeled tag.

HY-P78018

	PLAU/uPA Protein, Mouse (Biotinylated, HEK293, His-Avi) PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD	Mouse	HEK293
	PLAU or urokinase-type plasminogen activator (uPA) critically initiates fibrinolysis by cleaving plasminogen to form active plasmin.This enzymatic conversion is critical for regulating clot dissolution and tissue remodeling.PLAU/uPA Protein, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived PLAU/uPA protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P78195

	PLAU/uPA Protein, Human (Biotinylated, HEK293, His-Avi) PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD	Human	HEK293
	uPA chain A Protein, a key player in the plasminogen activation system, selectively cleaves plasminogen, initiating fibrinolysis and contributing to tissue remodeling. Its precision underscores its role in regulating proteolytic activity, emphasizing its significance in the cascade of events leading to fibrinolysis and extracellular matrix remodeling in various physiological processes. PLAU/uPA Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived PLAU/uPA protein, expressed by HEK293 , with C-His, C-Avi labeled tag.

HY-P75169

	GDNF Protein, Canine (HEK293, Fc) Glial cell line-derived neurotrophic factor; ATF; HFB1-GDNF; HGDNF; HSCR3	Canine	HEK293
	Glial-cell-line-derived neurotrophic factor (GDNF), a neurotrophic factor belongs to the GDNF family ligands (GFLs)., promotes survival of dopamine neurons. GDNF demonstrates a variety of neuroprotective roles for mammalian neurons. GDNF Protein, Canine (HEK293, Fc) is produced in HEK293 cells with a N-Terminal Fc-tag. It consists of 103 amino acids (R109-I211).

HY-P73074

	GDNF Protein, Human (HEK293) 1 Publications Verification Glial cell line-derived neurotrophic factor; ATF; HFB1-GDNF; HGDNF; HSCR3	Human	HEK293
	Glial-cell-line-derived neurotrophic factor (GDNF), a neurotrophic factor belongs to the GDNF family ligands (GFLs)., promotes survival of dopamine neurons. GDNF demonstrates a variety of neuroprotective roles for mammalian neurons. GDNF Protein, Human (HEK293) is produced in HEK293 cells, and consists of 103 amino acids (R83-I185).

HY-P700084AF

	Animal-Free GDNF Protein, Human (His) Glial cell line-derived neurotrophic factor; ATF; HFB1-GDNF; HGDNF; HSCR3	Human	E. coli
	Glial-cell-line-derived neurotrophic factor (GDNF), a neurotrophic factor belongs to the GDNF family ligands (GFLs)., promotes survival of dopamine neurons. GDNF demonstrates a variety of neuroprotective roles for mammalian neurons. Animal-Free GDNF Protein, Human (His), a recombinant animal-free protein, is produced in E.coil with a C-Terminal His-tag. It consists of 134 amino acids (S78-I211).This product is for cell culture use only.

HY-P73075

	GDNF Protein, Rat (sf9, His) Glial cell line-derived neurotrophic factor; ATF; HFB1-GDNF; HGDNF; HSCR3	Rat	Sf9 insect cells
	Glial-cell-line-derived neurotrophic factor (GDNF), a neurotrophic factor belongs to the GDNF family ligands (GFLs)., promotes survival of dopamine neurons. GDNF demonstrates a variety of neuroprotective roles for mammalian neurons. GDNF Protein, Rat (sf9, His) is produced in Sf9 insect cells with a N-Terminal His-tag. It consists of 134 amino acids (S78-I211).

HY-P7182

	GDNF Protein, Human 3 Publications Verification rHuGDNF; ATF	Human	E. coli
	Glial-cell-line-derived neurotrophic factor (GDNF), a neurotrophic factor belongs to the GDNF family ligands (GFLs)., promotes survival of dopamine neurons. GDNF demonstrates a variety of neuroprotective roles for mammalian neurons. GDNF Protein, Human is produced in E.coil, and consists of 134 amino acids (S78-I211).

HY-P7182A

	GDNF Protein, Human (His) rHuGDNF; ATF	Human	E. coli
	Glial-cell-line-derived neurotrophic factor (GDNF), a neurotrophic factor belongs to the GDNF family ligands (GFLs)., promotes survival of dopamine neurons. GDNF demonstrates a variety of neuroprotective roles for mammalian neurons. GDNF Protein, Human (His) is produced in E.coil with six N-Terminal His-tags. It consists of 134 amino acids (S78-I211).

HY-P7615

	ATF1 Protein, Human (His) rHuATF1, His; Cyclic AMP-dependent transcription factor ATF-1; cAMP-dependent transcription factor ATF-1; Activating transcription factor 1	Human	E. coli
	ATF1 Protein, Human (His) expressed in E. coli with a His tag. ATF1 is a member of the ATF/CREB family of transcription factors (TFs), specifically interacting with the consensus ATF/CRE site ‘TGACGTCA’.

HY-P7359

	GDNF Protein, Mouse (CHO) 2 Publications Verification rMuGDNF; GDNF; ATF	Mouse	CHO
	Glial-cell-line-derived neurotrophic factor (GDNF), a neurotrophic factor belongs to the GDNF family ligands (GFLs)., promotes survival of dopamine neurons. GDNF demonstrates a variety of neuroprotective roles for mammalian neurons. GDNF Protein, Mouse (CHO) is produced in CHO cells, and consists of 134 amino acids (S78-I211).

HY-P74408

	ATF2 Protein, Human (sf9, His-GST) Activating transcription factor 2; ATF2; CREB2; HB16	Human	Sf9 insect cells
	The ATF2 protein is a transcriptional activator that regulates anti-apoptotic genes, cell growth, and DNA damage responses. It binds to CRE and AP-1 sequences and plays a key role in nuclear transcription. ATF2 Protein, Human (sf9, His-GST) is the recombinant human-derived ATF2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P700179AF

	Animal-Free GDNF Protein, Mouse (His) rMuGDNF; GDNF; ATF	Mouse	E. coli
	Glial-cell-line-derived neurotrophic factor (GDNF), a neurotrophic factor belongs to the GDNF family ligands (GFLs)., promotes survival of dopamine neurons. GDNF demonstrates a variety of neuroprotective roles for mammalian neurons. Animal-Free GDNF Protein, Mouse (His), a recombinant animal-free protein, is produced in E.coil with a C-Terminal His-tag. It consists of 134 amino acids (S78-I211).This product is for cell culture use only.

HY-P73467

	PLAU/uPA Protein, Human (HEK293, His) Urokinase-type plasminogen activator; uPA; PLAU	Human	HEK293
	uPA chain A Protein, a key player in the plasminogen activation system, selectively cleaves plasminogen, initiating fibrinolysis and contributing to tissue remodeling. Its precision underscores its role in regulating proteolytic activity, emphasizing its significance in the cascade of events leading to fibrinolysis and extracellular matrix remodeling in various physiological processes. PLAU/uPA Protein, Human (HEK293, His) is the recombinant human-derived PLAU/uPA protein, expressed by HEK293 , with C-His labeled tag.

HY-P73561

	PLAU/uPA Protein, Rat (HEK293, His) Urokinase-type plasminogen activator; uPA; PLAU	Rat	HEK293
	PLAU/uPA proteins lack conserved residues critical for feature annotation propagation, suggesting potential differences in molecular interactions in plasminogen activation and fibrinolysis regulation. PLAU/uPA Protein, Rat (HEK293, His) is the recombinant rat-derived PLAU/uPA protein, expressed by HEK293 , with C-His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-B0075S

Melatonin-d4
Melatonin-d₄ is deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Antioxidative and anti-inflammatory properties . Melatonin is a selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation .

HY-B0075S1

Melatonin-d3

Melatonin-d₃ is the deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties . Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation . Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress .

HY-W011927S

4,4'-Sulfonyldiphenol-d8

1 Publications Verification

4,4'-Sulfonyldiphenol-d₈ (Bisphenol S (4,4'-Sulfonyldiphenol)-d₈) is the deuterium labeled 4,4'-Sulfonyldiphenol (HY-W011927).4,4'-Sulfonyldiphenol (Bisphenol S; Bis(4-hydroxyphenyl) sulfone), a substitute for Bisphenol A (HY-18260), is widely used in industrial and consumer products. 4,4'-Sulfonyldiphenol is an estrogen receptor (ER) agonist and can competitively bind to thyroid hormone receptors (TR) with IC₅₀ values for TRα and TRβ are 2650 μM and 2294 μM respectively, thereby affecting breast development and reducing the expression of androgen receptor (AR) in fetal testes. 4,4'-Sulfonyldiphenol promotes the progression of glioblastoma by upregulating the EZH2 mediated PI3K/AKT/mTOR pathway. Under chronic exposure, 4,4'-Sulfonyldiphenol can cause significant lipid deposition and dyslipidemia in the mouse liver by upregulating JunB and Atf3, and has a role in causing obesity at low doses. 4,4'-Sulfonyldiphenol induces intestinal inflammation by altering the intestinal microbiome. 4,4'-Sulfonyldiphenol accelerates the progression of atherosclerosis in zebrafish embryo larvae.

HY-B0075S2

Melatonin-d7

Melatonin-d₇ is the deuterium labeled Melatonin (HY-B0075). Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties . Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation . Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress .

HY-B1198S

Piperonyl butoxide-d9
Piperonyl butoxide-d₉ is the deuterium labeled Piperonyl butoxide.Piperonyl butoxide (ENT-14250) is a pesticide synergist and food additive. Piperonyl butoxide has adverse effects on reproduction, development and behavior in mice. Piperonyl butoxide can activate c-Jun and *ATF-2* in mouse hepatocytes. Piperonyl butoxide is a liver cancer carcinogen in rats and mice .

Host:	Mouse (9) Rabbit (20)
Reactivity:	Human (28) Rat (13) Mouse (16) human (1)
Application:	IHC-P (14) ICC/IF (13) IF-Tissue (2) IP (13) WB (27) FC (9) ELISA (10)
Isotype:	IgG (20) IgG1 (8)
Conjugation:	Non-conjugated (29) Biotin (2)
Clonality:	Polyclonal (2) Monoclonal (15) Monoclonal Antibody (2) Recombinant (10)
Modification:	Phosphorylated (1) Unmodified (19)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P83892

	PLAU Antibody (YA3589) ATF; QPD; UPA; URK; u-PA; BDPLT5	WB, ICC/IF, FC, ELISA	Human
	PLAU Antibody (YA3589) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PLAU.

HY-P83892A

	PLAU Antibody (YA3589)(PBS only) ATF; QPD; UPA; URK; u-PA; BDPLT5	WB, ICC/IF, FC, ELISA	Human
	PLAU Antibody (YA3589) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PLAU.

HY-P810358

	ATF1 Antibody (YA9680) Activating transcription factor 1, ATF 1, ATF1, ATF1 EWS fusion gene, ATF1 FUS fusion gene, ATF1_HUMAN, cAMP dependent transcription factor 1, cAMP-dependent transcription factor ATF-1, Cyclic AMP dependent transcription factor ATF 1, Cyclic AMP dependent transcription factor ATF1	WB, ICC/IF, IF-Tissue, IHC-P, FC	Human
	ATF1 Antibody (YA9680) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to ATF1.

HY-P82906

	ATF7 Antibody (YA2651) ATF7; ATFA; Cyclic AMP-dependent transcription factor ATF-7; cAMP-dependent transcription factor ATF-7; Activating transcription factor 7; Transcription factor ATF-A	WB	Human, Mouse, Rat
	ATF7 Antibody (YA2651) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATF7.

HY-P83391

	ATF1 Antibody (YA3136) Cyclic AMP-dependent transcription factor ATF-1; cAMP-dependent transcription factor ATF-1; Activating transcription factor 1 Protein TREB36; ATF1	WB, IP	Human
	ATF1 Antibody (YA3136) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATF1.

HY-P82439

	ATF5 Antibody (YA2184) ATF5; ATFX; Cyclic AMP-dependent transcription factor ATF-5; cAMP-dependent transcription factor ATF-5; Activating transcription factor 5; Transcription factor ATFx	WB, IHC-P, IP	Human, Mouse, Rat
	ATF5 Antibody (YA2184) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATF5.

HY-P83391A

	ATF1 Antibody (YA3136)(PBS only) Cyclic AMP-dependent transcription factor ATF-1; cAMP-dependent transcription factor ATF-1; Activating transcription factor 1 Protein TREB36; ATF1	WB, IP	Human
	ATF1 Antibody (YA3136) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATF1.

HY-P82439A

	ATF5 Antibody (YA2184)(PBS only) ATF5; ATFX; Cyclic AMP-dependent transcription factor ATF-5; cAMP-dependent transcription factor ATF-5; Activating transcription factor 5; Transcription factor ATFx	WB, IHC-P, IP	Human, Mouse, Rat
	ATF5 Antibody (YA2184) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATF5.

HY-P80554

	ATF6 Antibody (YA604) activating transcription factor 6; ATF6A	WB, IHC-P, IP	Human
	ATF6 Antibody (YA604) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATF6.

HY-P80379

	ATF6 Antibody (YA831) 2 Publications Verification	WB, IHC-P, FC	Human, Mouse, Rat
	ATF6 Antibody (YA831) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ATF6.

HY-P80486

	ATF4 Antibody (YA605) 1 Publications Verification	WB, ICC/IF, IHC-P, IP, FC	Human, Mouse, Rat
	ATF4 Antibody (YA605) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATF4.

HY-P84147

	ATF3 Antibody (YA3844)	ICC/IF, FC, ELISA	Human
	ATF3 Antibody (YA3844) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ATF3.

HY-P86626

	ATF6 Antibody (YA6318)	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	ATF6 Antibody (YA6318) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATF6.

HY-P82746

	GDNF Antibody (YA2491) ATF1; ATF2; gdnf; HFB1 GDNF; hGDNF; HSCR3	WB, FC	Human, Mouse, Rat
	GDNF Antibody (YA2491) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GDNF.

HY-P80554A

	ATF6 Antibody (YA604)(PBS only) activating transcription factor 6; ATF6A	WB, IHC-P, IP	Human
	ATF6 Antibody (YA604) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATF6.

HY-P810124

	ATF-7IP Antibody (YA9468)	WB, ICC/IF, IF-Tissue, IP, ELISA	human
	ATF-7IP Antibody (YA9468) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ATF-7IP.

HY-P84147A

	ATF3 Antibody (YA3844)(PBS only)	ICC/IF, FC, ELISA	Human
	ATF3 Antibody (YA3844) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ATF3.

HY-P86576

	ATF4 Antibody (YA6268) ATF4; CREB2; TXREB; Cyclic AMP-dependent transcription factor ATF-4; cAMP-dependent transcription factor ATF-4; Activating transcription factor 4; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding prot	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	ATF4 Antibody (YA6268) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATF4.

HY-P85048

	ATF-2 Antibody (YA4740) ATF2; CREB2; CREBP1; Cyclic AMP-dependent transcription factor ATF-2; cAMP-dependent transcription factor ATF-2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding pro	WB, IHC-P, ICC/IF, ELISA	Human, Mouse
	ATF-2 Antibody (YA4740) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to ATF-2.

HY-P80793

	*Phospho-ATF2 (Thr71) Antibody (YA224)* ATF2; CREB2; CREBP1; Cyclic AMP-dependent transcription factor ATF-2; cAMP-dependent transcription factor ATF-2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding pro	WB, ICC/IF, IP	Human, Mouse
	Phospho-ATF2 (Thr71) Antibody (YA224) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-ATF2 (Thr71).

HY-P80793A

	*Phospho-ATF2 (Thr71) Antibody (YA224)(PBS only)* ATF2; CREB2; CREBP1; Cyclic AMP-dependent transcription factor ATF-2; cAMP-dependent transcription factor ATF-2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding pro	WB, ICC/IF, IP	Human, Mouse
	Phospho-ATF2 (Thr71) Antibody (YA224) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-ATF2 (Thr71).

HY-P80552

	ATF2 Antibody (YA606) Activating transcription factor 2 antibody; Activating transcription factor 2 splice variant ATF2 var2 antibody; ATF 2 antibody; ATF-2 antibody; ATF2 antibody; ATF2 protein antibody; ATF2_HUMAN antibody; cAMP Response Element Binding Protein 2 antibody; cAMP response element binding protein CRE BP1 antibody; cAMP response element-binding protein CRE-BP1 antibody; cAMP responsive element binding protein 2, formerly antibody; cAMP-dependent transcription factor ATF-2 antibody; cAMP-responsive element-binding protein 2 antibody; CRE BP1 antibody; CRE-BP antibody; CREB 2 antibody; CREB-2 antibody; CREB2 antibody; CREBP1 antibody; Cyclic AMP dependent transcription factor ATF 2 antibody; Cyclic AMP-dependent transcription factor ATF-2 antibody; Cyclic AMP-responsive element-binding protein 2 antibody; D130078H02Rik antibody; D18875 antibody; HB 16 antibody; HB16 antibody; Histone acetyltransferase ATF2 antibody; MGC105211 antibody; MGC105222 antibody; MGC111558 antibody; MGC142504 antibody; mXBP antibody; MXBP protein antibody; Tg(Gzma-Klra1)7Wum antibody; TREB 7 antibody; TREB7 antibody	WB	Human, Mouse, Rat
	ATF2 Antibody (YA606) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATF2.

HY-P80553

	ATF4 Antibody 2 Publications Verification Cyclic AMP-dependent transcription factor ATF-4; CREB-2; cAMP-responsive element-binding protein 2; DNA-binding protein TAXREB67	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	ATF4 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to ATF4.

HY-P80552A

	ATF2 Antibody (YA606)(PBS only) Activating transcription factor 2 antibody; Activating transcription factor 2 splice variant ATF2 var2 antibody; ATF 2 antibody; ATF-2 antibody; ATF2 antibody; ATF2 protein antibody; ATF2_HUMAN antibody; cAMP Response Element Binding Protein 2 antibody; cAMP response element binding protein CRE BP1 antibody; cAMP response element-binding protein CRE-BP1 antibody; cAMP responsive element binding protein 2, formerly antibody; cAMP-dependent transcription factor ATF-2 antibody; cAMP-responsive element-binding protein 2 antibody; CRE BP1 antibody; CRE-BP antibody; CREB 2 antibody; CREB-2 antibody; CREB2 antibody; CREBP1 antibody; Cyclic AMP dependent transcription factor ATF 2 antibody; Cyclic AMP-dependent transcription factor ATF-2 antibody; Cyclic AMP-responsive element-binding protein 2 antibody; D130078H02Rik antibody; D18875 antibody; HB 16 antibody; HB16 antibody; Histone acetyltransferase ATF2 antibody; MGC105211 antibody; MGC105222 antibody; MGC111558 antibody; MGC142504 antibody; mXBP antibody; MXBP protein antibody; Tg(Gzma-Klra1)7Wum antibody; TREB 7 antibody; TREB7 antibody	WB	Human, Mouse, Rat
	ATF2 Antibody (YA606) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATF2.

HY-P83667

	*Phospho-ATF4 (Ser219) Antibody* Cyclic AMP-dependent transcription factor ATF-4; CREB-2; cAMP-responsive element-binding protein 2; DNA-binding protein TAXREB67	WB	Human
	Phospho-ATF4 (Ser219) Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Phospho-ATF4 (Ser219).

HY-P84148

	ATF4 Antibody (YA3845) CREB2; TXREB; CREB-2; TAXREB67	WB, IHC-P, ELISA	Human
	ATF4 Antibody (YA3845) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ATF4.

HY-P84148A

	ATF4 Antibody (YA3845)(PBS only) CREB2; TXREB; CREB-2; TAXREB67	WB, IHC-P, ELISA	Human
	ATF4 Antibody (YA3845) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ATF4.

HY-P83503

	uPA Antibody (YA3248) Urokinase-type plasminogen activator; U-plasminogen activator; Upa; PLAU; ATF uPA	WB, IHC-P	Human, Mouse, Rat
	uPA Antibody (YA3248) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to uPA.

HY-P83503A

	uPA Antibody (YA3248)(PBS only) Urokinase-type plasminogen activator; U-plasminogen activator; Upa; PLAU; ATF uPA	WB, IHC-P	Human, Mouse, Rat
	uPA Antibody (YA3248) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to uPA.

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