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Acid Phosphatase 3

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Phosphatase (4) 17β-HSD (1) Dopamine Receptor (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (2) Metabolic Disease (1)

Inhibitors & Agonists

Fluorescent Dyes

Recombinant Proteins

Antibodies

Targets Recommended: Phosphatase SHP2 PhosTACs PTEN SHP1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-176567

ACP3 ligand 1	Phosphatase	Cancer
ACP3 ligand 1 is a ligand of Acid Phosphatase 3 (ACP3, ACPP). ACP3 ligand 1 interacts with ACP3 expressed on the surface of tumor cells for in vivo pharmaco-delivery applications .

HY-123846

MLS-0437605 1 Publications Verification	Phosphatase	Cardiovascular Disease
MLS-0437605 is a selective *dual-specificity phosphatase 3* (DUSP3) inhibitor with an IC₅₀** of 3.7 μM. MLS-0437605 is more selective for DUSP3 than DUSP22 and other protein tyrosine phosphatases (PTPs) .

HY-106447

Losulazine	Phosphatase 17β-HSD Dopamine Receptor	Cardiovascular Disease
Losulazine is an orally active antihypertensive agent. Losulazine modulates acid *phosphatase*, 3β-hydroxysteroid dehydrogenase, and 17β-hydroxysteroid dehydrogenase activity. Losulazine can be used for the research of hypertension .

HY-W009458

3-Indoxyl phosphate sodium 3-IP sodium	Phosphatase	Metabolic Disease
3-Indoxyl phosphate (3-IP) is a chromogenic and electrochemical substrate for alkaline phosphatase. Upon enzymatic cleavage by alkaline phosphatase, 3-indoxyl is released and subsequently oxidized to produce water-insoluble indigo, which can be quantified by colorimetric detection at 660 nm as a measure of alkaline phosphatase activity. 3-Indoxyl phosphate can also be converted to water-soluble leucoindigo by reduction of indigo in alkaline solution by sodium dithionite, which can be quantified by colorimetric detection at 415 nm or voltametric detection as a measure of alkaline phosphatase activity.2 3-Indoxyl phosphate has been used in ELISAs.

Cat. No.	Product Name	Type

HY-W009458

3-Indoxyl phosphate sodium 3-IP sodium	Fluorescent Dyes
3-Indoxyl phosphate (3-IP) is a chromogenic and electrochemical substrate for alkaline phosphatase. Upon enzymatic cleavage by alkaline phosphatase, 3-indoxyl is released and subsequently oxidized to produce water-insoluble indigo, which can be quantified by colorimetric detection at 660 nm as a measure of alkaline phosphatase activity. 3-Indoxyl phosphate can also be converted to water-soluble leucoindigo by reduction of indigo in alkaline solution by sodium dithionite, which can be quantified by colorimetric detection at 415 nm or voltametric detection as a measure of alkaline phosphatase activity.2 3-Indoxyl phosphate has been used in ELISAs.

3-Indoxyl phosphate sodium

3-IP sodium

Fluorescent Dyes

3-Indoxyl phosphate (3-IP) is a chromogenic and electrochemical substrate for alkaline phosphatase. Upon enzymatic cleavage by alkaline phosphatase, 3-indoxyl is released and subsequently oxidized to produce water-insoluble indigo, which can be quantified by colorimetric detection at 660 nm as a measure of alkaline phosphatase activity. 3-Indoxyl phosphate can also be converted to water-soluble leucoindigo by reduction of indigo in alkaline solution by sodium dithionite, which can be quantified by colorimetric detection at 415 nm or voltametric detection as a measure of alkaline phosphatase activity.2 3-Indoxyl phosphate has been used in ELISAs.

Species:	Human (2)
Tag:	His (1) Tag Free (2)
Source:	Sf9 insect cells (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71150

	DUSP3 Protein, Human (His) Dual specificity protein Phosphatase 3; DUSP3; Dual specificity protein Phosphatase VHR; Vaccinia H1-related Phosphatase; VHR	Human	E. coli
	DUSP3, a dual-specificity phosphatase, preferentially dephosphorylates phosphotyrosines. Its main function involves inactivating ERK1 and ERK2, thereby modulating associated cellular signaling pathways. DUSP3 Protein, Human (His) is the recombinant human-derived DUSP3 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P703898

	DUSP3 Protein, Human (sf9) Dual specificity protein Phosphatase 3; DUSP3; Dual specificity protein Phosphatase VHR; Vaccinia H1-related Phosphatase; VHR	Human	Sf9 insect cells
	DUSP3, a dual-specificity phosphatase, preferentially dephosphorylates phosphotyrosines. Its main function involves inactivating ERK1 and ERK2, thereby modulating associated cellular signaling pathways. DUSP3 Protein, Human (sf9) is the recombinant human-derived DUSP3 protein, expressed by Sf9 insect cells, with tag free.

HY-P703425

	serB2 Protein, Mycobacterium tuberculosis Phosphoserine Phosphatase SerB2; O-phosphoserine phosphohydrolase; Protein-serine/threonine Phosphatase; 3.1.3.16; serB2; Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); Hydrolase; 3.1.3.3	Others	E. coli
	serB2 Protein, Mycobacterium tuberculosis is the recombinant serB2, expressed by E. coli , with tag Free labeled tag. ,

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Host:	Mouse (2) Rabbit (3)
Reactivity:	Human (4) Mouse (1) Rat (2) human (1)
Application:	IHC-P (4) ICC/IF (4) IP (2) WB (5) FC (2) ELISA (2)
Isotype:	IgG (4)
Conjugation:	Non-conjugated (5)
Clonality:	Monoclonal (4) Recombinant (2)
Modification:	Unmodified (5)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82879

	Cdc25C Antibody (YA2624) CDC25C; M-phase inducer Phosphatase 3; Dual specificity Phosphatase Cdc25C	WB, IHC-P, ICC/IF, IP, FC	Human
	Cdc25C Antibody (YA2624) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cdc25C.

HY-P85096

	Cdc25C Antibody (YA4788) CDC25C; M-phase inducer Phosphatase 3; Dual specificity Phosphatase Cdc25C	WB, IHC-P, ICC/IF, ELISA	Human
	Cdc25C Antibody (YA4788) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Cdc25C.

HY-P86209

	Cdc25C Antibody (YA5901) CDC25C; M-phase inducer Phosphatase 3; Dual specificity Phosphatase Cdc25C	WB, IHC-P, ICC/IF, IP, ELISA	Human, Rat
	Cdc25C Antibody (YA5901) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cdc25C.

HY-P87014

	PPP3CB Antibody (YA6707) Calcineurin A beta antibody; Calcineurin A2 antibody; Calcineurin B, formerly antibody; Calmodulin dependent calcineurin A subunit beta isoform antibody; Calmodulin-dependent calcineurin A subunit beta isoform antibody; CALNA 2 antibody; CALNA2 antibody; CALNB antibody; CAM PRP catalytic subunit antibody; CAM-PRP catalytic subunit antibody; Calcineurin A beta antibody; Calcineurin A2 antibody; Calcineurin B, formerly antibody; Calmodulin dependent calcineurin A subunit beta isoform antibody; Calmodulin-dependent calcineurin A subunit beta isoform antibody; CALNA 2 antibody; CALNA2 antibody; CALNB antibody; CAM PRP catalytic subunit antibody; CAM-PRP catalytic subunit antibody; CNA2 antibody; CnAbeta antibody; PP2BB_HUMAN antibody; PP2Bbeta antibody; PPP3CB antibody; Protein Phosphatase 2B, catalytic subunit, beta isoform, formerly antibody; Protein Phosphatase 3 (formerly 2B) catalytic subunit beta isoform antibody; Protein Phosphatase 3 catalytic subunit beta isoform antibody; Protein Phosphatase 3 catalytic subunit beta isozyme antibody; Serine/threonine protein Phosphatase 2B catalytic subunit beta isoform antibody; Serine/threonine-protein Phosphatase 2B catalytic subunit beta isoform antibody;	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	PPP3CB Antibody (YA6707) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PPP3CB.

HY-P89991

	PAP-2b Antibody (YA9335) LPP3, PPAP2B, PLPP3, Phospholipid Phosphatase 3, Lipid phosphate phosphohydrolase 3, PAP2-beta, Phosphatidate phosphohydrolase type 2b, Phosphatidic Acid Phosphatase 2b, Vascular endothelial growth factor and type I collagen-inducible protein, PAP-2b, PAP2b, VCIP	WB	human
	PAP-2b Antibody (YA9335) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to PAP-2b.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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