32 Results for "

Ang 2

" in MedChemExpress (MCE) Product Catalog:
Products (32)

32 Results for "Ang 2" in MCE Product Catalog:

  • Recombinant Proteins Recommended:
3
3 Cited Publications
Cat. No.: HY-P7510
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuAngiopoietin-2, His; AngPT2; Ang2; Angiopoietin-2
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P72829
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Angiopoietin-2; Ang-2; AngPT2
Species:  
Source:  
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Cat. No.: HY-P99116
CAS No.: 1607793-29-2
Synonyms: RG7716; RO-6867461
Faricimab, an overall good safety and tolerability profile, is a bispecific antibody targeting Angiopoietin-2 (Ang-2) and vascular endothelial growth factor-A (VEGF-A). Faricimab prevents retinal vascular leakage, cell death and inflammation in retinal ischemia/reperfusion (I/R) injury and sCNV mouse models. Faricimab demonstrates statistically superior visual acuity gains versus Ranibizumab (HY-P9951). Faricimab can be used for retinal diseases, such as age-related macular degeneration (w-AMD), diabetic macular edema (DME) and macular edema following retinal vein occlusion (RVO) .
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Cat. No.: HY-P99330
CAS No.: 1448221-05-3
Synonyms: Anti-Human VEGFA Recombinant Antibody; RO5520985

Target:  

VEGFR Tie

Research Areas:  

Cancer

Vanucizumab is a first-in-class, bispecific IgG1-like monoclonal antibody that simultaneously blocks VEGF-A and angiopoietin-2 (Ang-2) from interacting with their receptors. Vanucizumab has antiangiogenic and anticancer effects .
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Cat. No.: HY-P99036
CAS No.: 1296818-77-3

Target:  

Tie

Nesvacumab is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically binds and inactivates the Tie2 receptor ligand Angiopoietin-2 (Ang2) with high affinity, but shows no binding to Ang1. Nesvacumab can be used in vascular researches .
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Cat. No.: HY-P99510
CAS No.: 2415205-37-5
Synonyms: LY-3127804

Target:  

Tie

Research Areas:  

Inflammation/Immunology Cancer

Zansecimab (LY-3127804) is a monoclonal antibody against angiopoietin 2 (Ang‑2). Zansecimab can be used in research on angiogenesis, immunomodulation and anti-tumor activity .
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Cat. No.: HY-P99546
CAS No.: 894356-79-7
Synonyms: 2xCon4C; AMG 386

Target:  

Tie

Research Areas:  

Cardiovascular Disease Cancer

Trebananib (2xCon4C) is an Fc fusion peptibody. Trebananib exerts its effects by blocking the binding of angiopoietin 1 (Ang1) and angiopoietin 2 (Ang2) to the TIE2 receptor. Trebananib has anti-angiogenic and anti-tumor activities .
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Cat. No.: HY-P990689
CAS No.: 2517939-46-5
Synonyms: RO-7250284

Target:  

VEGFR

Research Areas:  

Neurological Disease

Zifibancimig (RO-7250284) is a monoclonal antibody against VEGF-A and Ang-2, with affinities of 4 pM and 2 pM, respectively. Zifibancimig has high stability, maintains target-binding capability under physiological stress and storage conditions, and is designed for sustained long-term ocular delivery via the Port Delivery implant device. Zifibancimig can be used in the research of retinal diseases .
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Cat. No.: HY-N2666
CAS No.: 132185-83-2
5α-Hydroxycostic acid, a eudesmane-type sesquiterpene, is isolated from the herb Laggera alata. 5α-Hydroxycostic acid inhibits angiogenesis and suppresses breast cancer cell migration through regulating VEGF/VEGFR2 and Ang2/Tie2 pathways .
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Cat. No.: HY-P990625
CAS No.: 1415642-51-1

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

MEDI-3617 is a humanized antibody expressed in CHO cells, targeting Ang2/ANGPT2/Angiopoietin2. MEDI-3617 has a huIgG2 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for MEDI-3617 can refer to Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-P990334

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Anti-ANGPT2 Antibody is a CHO-expressed human antibody that targets Ang2/ANGPT2/Angiopoietin2. Anti-ANGPT2 Antibody has a huIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-ANGPT2 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P991415
Synonyms: AM712

Target:  

VEGFR Tie

Research Areas:  

Others

ASKG-712 (AM712) is a recombinant anti-VEGF humanized monoclonal antibody and Ang-2 antagonist peptide fusion protein. ASKG-712 can be used in Wet age-related macular degeneration and Diabetic macular oedema research .
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Cat. No.: HY-114164E
CAS No.: 9002-04-4
Rabbit Thrombin is a serine protease. Rabbit Thrombin forms a covalent complex with antithrombin III and reversibly binds endothelial cell surface high-affinity sites. Rabbit Thrombin regulates VEGF and Ang-2, potentiates VEGF mitogenic activity and protects endothelial cells from apoptosis. Rabbit Thrombin can be used for the research of hindlimb ischemia .
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Cat. No.: HY-P991663

Target:  

Tie

Research Areas:  

Cancer

AMG-780 is a fully human IgG2 antibody that targets angiopoietin 1 (Ang1) (IC50 = 4.5 nM) and angiopoietin 2 (Ang2) (IC50 = 0.06 nM). AMG-780 inhibits tumor growth in the Colo205 xenograft mouse model by inhibiting both Ang1 and Ang2. AMG-780 is indicated for the research of cancers such as colon cancer .
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Cat. No.: HY-P700396
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Angiopoietin 2; Angiopoietin-2; Ang2; Ang-2; Tie2-ligand; Angiopoietin-2B; Angiopoietin-2a; Ang2; AGPT2;
Species:  
Dog
Source:  
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Cat. No.: HY-P72828
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Angiopoietin-2; Ang-2; AngPT2
Species:  
Source:  
CHO
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Cat. No.: HY-P704354
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Angiopoietin-2; Ang-2; AngPT2
Species:  
Source:  
CHO
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Cat. No.: HY-P72827
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Angiopoietin-2; Ang-2; AngPT2
Species:  
Source:  
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Cat. No.: HY-P72830
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Angiopoietin-2; Ang-2; AngPT2
Species:  
Source:  
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Cat. No.: HY-P7844
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuAngiopoietin-2/Ang2, Fc ; AGPT2; Ang2; Ang-2; Angiopoietin 2; Angiopoietin-2; Angiopoietin-2a; Angiopoietin-2B; Angiopoitin 2; AngPT2; Tie2-ligand
Species:  
Source:  
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