Copy Link Print Information

Vanucizumab

(Synonyms: Anti-Human VEGFA Recombinant Antibody; RO5520985)
Customer Review

Based on 1 Customer Validation

Vanucizumab is a first-in-class, bispecific IgG1-like monoclonal antibody that simultaneously blocks VEGF-A and angiopoietin-2 (Ang-2) from interacting with their receptors. Vanucizumab has antiangiogenic and anticancer effects.

For research use only. We do not sell to patients.

  • Purity: 95.12%
  • CAS No.: 1448221-05-3
  • Molecular Weight:146.89 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Vanucizumab
  • Experimental Validation Results for Vanucizumab
  • Experimental Validation Results for Vanucizumab
  • Experimental Validation Results for Vanucizumab
  • Vanucizumab Chemical Structure
    Vanucizumab Chemical Structure
CAS No.: 1448221-05-3
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Purity & Documentation
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

All VEGFR Isoforms

More

All Tie Isoforms

More
Keywords
100 mg

Get Quote In-stock

Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    IgG1-kappa-lambda with half-IG VL-CH1/VH-CK crossover

  • 1/16

    Immobilized Human VEGFA, His Tag can bind Vanucizumab. The EC50 for this effect is 4.575 ng/mL.

  • 1/16

    Immobilized Human ANGPT2, His Tag can bind Vanucizumab. The EC50 for this effect is 78.70 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 HeLa cells with Vanucizumab (HY-P99330, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control.

  • Vanucizumab Chemical Structure
    1/16
  • Vanucizumab
  • Immobilized Human VEGFA, His Tag can bind Vanucizumab. The EC50 for this effect is 4.575 ng/mL.
  • Immobilized Human ANGPT2, His Tag can bind Vanucizumab. The EC50 for this effect is 78.70 ng/mL.
  • Flow cytometric analysis of 1X106 HeLa cells with Vanucizumab (HY-P99330, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control.
  • IgG1-kappa-lambda with half-IG VL-CH1/VH-CK crossover