107 Results for "

CD2

" in MedChemExpress (MCE) Product Catalog:
Products (107)

107 Results for "CD2" in MCE Product Catalog:

38
38 Publications Verification
Cat. No.: HY-101103
CAS No.: 128446-35-5
Purity:  99.74%
Synonyms: (2-Hydroxypropyl)-β-cyclodextrin
HP-β-CD ((2-Hydroxypropyl)-β-cyclodextrin) is a widely used drug delivery vehicle to improve the stability and bioavailability.
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19
19 Cited Publications
Cat. No.: HY-126823
CAS No.: 234075-45-7
Purity:  95.33%
Synonyms: PGSK diacetate (5/6-mixture)
Target:  

Fluorescent Dye

Research Areas:  

Others

Phen green SK (PGSK) diacetate (PGSK diacetate (5/6-mixture)) is a metal ion-sensitive fluorescent probe that can penetrate cell membranes. Phen green SK (PGSK) diacetate can react with a variety of metal ions, including Fe 2+, Cd 2+, Co 2+, Ni 2+, Zn 2+, etc. Phen green SK (PGSK) diacetate chelates Fe 2+, resulting in fluorescence quenching, which can be restored when a membrane-permeable chelator is added, thereby reflecting the changes in the intracellular chelatable iron pool. The excitation/emission maxima of Phen green SK diacetate are 507/532 nm, respectively [2] .
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1
1 Cited Publications
Cat. No.: HY-13756S
CAS No.: 1356841-89-8
Purity:  98.36%
Synonyms: FK506-13C,d2; Fujimycin-13C,d2; FR900506-13C,d2
Tacrolimus- 13C,d2 (FK506- 13C,d2) is the 13C, deuterated-labeled Tacrolimus (HY-13756). Tacrolimus (FK506), a molecular glue, a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties .
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1
1 Cited Publications
Cat. No.: HY-15703
CAS No.: 1237744-13-6
Purity:  99.46%
Target:  

iGluR

Research Areas:  

Neurological Disease

QNZ46 is a highly selective noncompetitive NMDA receptor antagonist targeting GluN2C/D (IC50=3.9 μM), GluN1/GluN2C (IC50=7.1 μM), and GluN1/GluN2D (IC50=182 μM) subunits. QNZ46 inhibits glutamate-mediated calcium influx, thereby blocking excitotoxicity. QNZ46 is membrane permeable and can cross the blood-brain barrier, where it inhibits myelin damage and axonal degeneration [2] .
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Cat. No.: HY-P99904
CAS No.: 288392-69-8
Synonyms: MEDI-507; TCD601

Target:  

CD2

Research Areas:  

Inflammation/Immunology Cancer

Siplizumab (MEDI-507) is a humanized IgG1 monoclonal antibody against CD2. Siplizumab depletes T cells, decreases T cell activation, inhibites T cell proliferation and enriches naïve and bona fide regulatory T cells .
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Cat. No.: HY-158109
Purity:  99.39%
M3554 is an anti-GD2 antibody-drug conjugate (ADC) based on the humanized anti-GD2 antibody. M3554 consists of the humanized monoclonal antibody hu14.18 (K322A) (HY-P991040) linked to a topoisomerase 1 inhibitor Exatecan (HY-13631) via a cleavable β-glucuronide linker. M3554 can be used for the study of neuroblastoma, osteosarcoma or glioma .
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Cat. No.: HY-W011060
CAS No.: 23978-09-8
Synonyms: 4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane
Cryptand 2.2.2 (4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane) is a metal ion chelator. Cryptand 2.2.2 forms stable mononuclear, protonated and dinuclear complexes with copper (II) ions; forms protonated complexes with hydrogen ions; and also forms stable complexes with Zn 2+, Co 2+, Ni 2+, Cd 2+, Hg 2+ and Pb 2+ ions. Cryptand 2.2.2 can be used for the preparation of nanoparticles, transition metal compounds, etc.
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Cat. No.: HY-P99454
CAS No.: 1826819-58-2
Synonyms: ABBV-838
Research Areas:  

Cancer

Azintuxizumab vedotin (ABBV-838) is an antibody–drug conjugate (ADC) targeting a unique epitope of CD2 subset 1, a cell-surface glycoprotein expressed on multiple myeloma cells .
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Cat. No.: HY-137428
CAS No.: 20846-91-7
Purity:  ≥98.0%
Research Areas:  

Others

(S,S)-EDDS is a chelating agent and a structural isomer of EDTA (HY-Y0682), which forms complexes with Co 2+, Ni 2+, Cu 2+, Zn 2+ and Cd 2+ [2].
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Cat. No.: HY-W012683
CAS No.: 142-73-4
Iminodiacetic acid is a metal ion chelator targeting Cr 6+, Cd 2+, Ni 2+, and Pb 2+. Iminodiacetic acid selectively and irreversibly binds metal ions through the coordination of carboxyl and imino groups, reduces the toxicity of metal ions and promotes their adsorption and separation. Iminodiacetic acid has the functions of heavy metal ion removal and coordination complex stabilization. Iminodiacetic acid is often used in environmental pollution control (such as heavy metal adsorption in water) and coordination chemistry (such as metal ion detection and separation) research [2] .
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Cat. No.: HY-W244398
CAS No.: 13239-97-9
2-Thiocytidine is a natural thionucleoside in prokaryotic tRNA, which is biosynthesized under the catalysis of intracellular sulfur transferase systems and possesses multiple activities such as metal coordination and nucleic acid conformation regulation. 2-Thiocytidine forms stable Zn 2+ and Cd 2+ complexes via its (C2) S group, with partial involvement of N3; metal binding acidifies the deprotonation process of (C4) NH2. 2-Thiocytidine can be used in related research in various fields including nanotechnology and click chemistry for interstrand DNA crosslinking [2].
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Cat. No.: HY-B0166S6
CAS No.: 82977-10-4
Synonyms: L-Ascorbate-d2; Vitamin C--d2
L-Ascorbic acid-d2 is the deuterium labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a colla
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Cat. No.: HY-P990286

Target:  

CD2

Research Areas:  

Inflammation/Immunology Cancer

Anti-Rat CD2 Antibody (OX-34) is mouse-derived IgG2a κ type antibody inhibitor, targeting to rat CD2. Anti-Rat CD2 Antibody (OX-34) can block CD2 and inhibit the mixed lymphocyte reaction. Anti-Rat CD2 Antibody (OX-34) can be used for the researches of cancer, inflammation and immunology, such as RNK-16 tumor and arthritis [2] .
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Cat. No.: HY-B0252S1
CAS No.: 1190006-03-1
Synonyms: HCTZ-13C,d2
Hydrochlorothiazid- 13C,d2 is the 13C- and deuterium labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect [2] .
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Cat. No.: HY-P990868

Target:  

CD2

Research Areas:  

Inflammation/Immunology Cancer

Anti-CD2 Antibody (CB.219) is an anti-human CD2 IgG2b monoclonal antibody. Anti-CD2 Antibody (CB.219) can reduce the infiltration of T cells, macrophages, and the number of Tregs in the colon. Anti-CD2 Antibody (CB.219) can be used for research on infection and inflammation such as toxoplasma infection and colitis. The recommend isotype control of Anti-CD2 Antibody (CB.219): Mouse IgG2b kappa, Isotype Control (HY-P99982) [2].
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Cat. No.: HY-P991543
CAS No.: 339181-10-1
Target:  

CD2

Research Areas:  

Inflammation/Immunology Cancer

BTI-322 is a human IgG1κ antibody directed against the CD2 antigen on T cells and NK cells. BTI-322 can block primary and memory alloantigen proliferative responses in vitro. BTI-322 recognizes over 90% of E-rosette-forming peripheral blood lymphocytes and T-cell leukemias. BTI-322 has immunosuppressive activity. BTI-322 effectively inhibits T cell responses in vitro to allogeneic cells. BTI-322 can be used as a T-cell deplting agent. BTI-322 can be studied in research for renal allograft rejection and steroid-refractory acute graft-versus-host disease [2].
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Cat. No.: HY-RS02204
Research Areas:  

Others

CD2 Human Pre-designed siRNA Set A contains three designed siRNAs for CD2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-N1415S1
CAS No.: 3028869-04-4
Synonyms: (-)-(E)-Caryophyllene-13C,d2; (−)-β-caryophyllene-13C,d2; (−)-trans-Caryophyllene-13C,d2
β-Caryophyllene- 13C,d2 is 13C and deuterated labeled β-Caryophyllene (HY-N1415). β-Caryophyllene is a CB2 receptor agonist .
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Cat. No.: HY-P992560
Target:  

CD2

Research Areas:  

Cancer

Anti-Mouse CD2 Antibody (RM2-5) is a CD2-blocking monoclonal antibody. Anti-Mouse CD2 Antibody (RM2-5) reduces pro-inflammatory cytokines, inhibits T helper cell differentiation, and modulates Treg survival by blocking CD48-mediated T cell activation/adhesion and CD2-mediated co-stimulatory signaling. Anti-Mouse CD2 Antibody (RM2-5) can be used for research on B cell lymphoma [2] .
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Cat. No.: HY-RS02224
Research Areas:  

Others

CD2AP Human Pre-designed siRNA Set A contains three designed siRNAs for CD2AP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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