Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
260 Results for "
Cyclooxygenase inhibitor
" in MedChemExpress (MCE) Product Catalog:
Products (260)
260 Results for "Cyclooxygenase inhibitor" in MCE Product Catalog:
76
76 Publications Verification
Synonyms: Paracetamol; 4-Acetamidophenol; 4'-Hydroxyacetanilide
38
38 Cited Publications
Synonyms: Acetylsalicylic acid; ASA
Aspirin (Acetylsalicylic acid) is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively. Aspirin induces apoptosis. Aspirin inhibits the activation of NF-κB. Aspirin also inhibits platelet prostaglandin synthetase, and can prevent coronary artery and cerebrovascular thrombosis .
21
21 Cited Publications
Synonyms: (+)-Catechin; Cianidanol; Catechuic acid
21
21 Cited Publications
Target:
Research Areas:
NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM.
21
21 Cited Publications
Cat. No.: HY-N0355
CAS No.: 225937-10-0
Category:
Flavonoids Flavanols Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Cancer Theaceae
Target:
19
19
19 Cited Publications
Synonyms: 3,4,5-Trihydroxybenzoic acid hydrate
17
17 Cited Publications
Synonyms: (-)-Epicatechol; Epicatechin; epi-Catechin
Category:
Anti-aging Plants Camellia sinensis (L.) O. Ktze. Endogenous metabolite Flavonoids Sunscreen Flavanols Phenols Polyphenols Cosmetic Research Disease Research Fields Inflammation/Immunology Cancer Theaceae
Target:
16
16
16 Cited Publications
Synonyms: Salicylic acid sodium salt; 2-Hydroxybenzoic acid sodium salt
10
Target:
Research Areas:
Ketoprofen (RP-19583) is a non-steroidal anti-inflammatory agent. Ketoprofen can inhibits the activity of cyclooxygenase with IC50 values of 2 nM (COX-1) and 26 nM (COX-2). which is potential in the research of inflammation, immunology, and metabolic disease such as obesity .
9
Research Areas:
Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca 2+ channels, modulating non-selective cation channels (NSC), activating K + channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.
8
8 Cited Publications
Synonyms: Epicatechin gallate; ECG; (-)-Epicatechin 3-O-gallate
Category:
Flavonoids Flavanols Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Cancer Theaceae
Target:
5
5 Cited Publications
Cat. No.: HY-112482
CAS No.: 214697-26-4
Target:
Research Areas:
ABT-702 (Adenosine Kinase Inhibitor) is a potent, orally active, and selective adenosine kinase (AK) inhibitor with an IC50 of 1.7 nM. ABT-702 shows >1300-fold selectivity for AK over other biological targets, including cyclooxygenases-1 and -2. ABT-702 attenuates inflammation in diabetic retinopathy by increasing free adenosine levels. ABT-702 shows analgesic and anti-inflammatory effects in vivo. ABT-702 can be used for diabetic retinopathy research .
5
5 Cited Publications
Cat. No.: HY-112482A
CAS No.: 2624336-92-9
Target:
Research Areas:
ABT-702 hydrochloride is a potent, orally active, and selective adenosine kinase (AK) inhibitor with an IC50 of 1.7 nM. ABT-702 hydrochloride shows >1300-fold selectivity for AK over other biological targets, including cyclooxygenases-1 and -2. ABT-702 hydrochloride attenuates inflammation in diabetic retinopathy by increasing free adenosine levels. ABT-702 hydrochloride shows analgesic and anti-inflammatory effects in vivo. ABT-702 hydrochloride can be used for diabetic retinopathy research .
4
4 Cited Publications
Synonyms: [6]-Gingerone; [6]-Paradol
Category:
Zingiber officinale Roscoe Monophenols Phenols Plants Disease Research Fields Cancer Zingiberaceae
Target:
4
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer .
3
3 Cited Publications
Target:
Research Areas:
SKF-86002 is an orally active p38 MAPK inhibitor, with anti-inflammatory, anti-arthritic and analgesic activities. SKF-86002 inhibits lipopolysaccharide (LPS)-stimulate human monocyte IL-1 and TNF-α production (IC50 = 1 μM). SKF-86002 inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid .
2
Target:
Research Areas:
Indobufen is a platelet aggregation inhibitor. Indobufen is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes .
2
2 Cited Publications
Synonyms: Dipyrone hydrate; Methamizole sodium hydrate
Research Areas:
Metamizole sodium hydrate (Dipyrone) is an orally active cyclooxygenase (COX) inhibitor.. Metamizole sodium hydrate can inhibit cell proliferation and promote cell apoptosis. Metamizole sodium hydrate has anti-inflammatory and antioxidant activities. Metamizole sodium hydrate is an antipyretic, analgesic and spasmolytic agent. Metamizole sodium hydrate can be used in research to relieve a variety of pain .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
