165 Results for "

Cys113

" in MedChemExpress (MCE) Product Catalog:
Products (165)

165 Results for "Cys113" in MCE Product Catalog:

13
13 Cited Publications
Art. -Nr.: HY-P0256
CAS. Nr.: 24345-16-2
Synonyms: Apamine
Apamin (Apamine) is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom), is known as a specifically selective blocker of Ca 2+-activated K + (SK) channels and exhibits anti-inflammatory and anti-fibrotic activity .
loading...
    loading...
13
13 Cited Publications
Art. -Nr.: HY-P0256A
Synonyms: Apamine TFA
Apamin TFA (Apamine TFA) is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom), is known as a specifically selective blocker of Ca 2+-activated K + (SK) channels and exhibits anti-inflammatory and anti-fibrotic activity .
loading...
    loading...
10
10 Cited Publications
Art. -Nr.: HY-P0202
CAS. Nr.: 117399-94-7
Synonyms: ET-1 (swine, human)
Endothelin 1 (swine, human) (ET-1) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ETA and ETB .
loading...
    loading...
10
10 Cited Publications
Art. -Nr.: HY-P0049
CAS. Nr.: 113-79-1
Synonyms: Arg8-vasopressin; AVP
Target:  

Vasopressin Receptor

Forschungsgebiete:  

Neurological Disease Cancer

Argipressin (Arg8-vasopressin) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1.
loading...
    loading...
10
10 Cited Publications
Art. -Nr.: HY-W539944
CAS. Nr.: 129979-57-3
Synonyms: Arg8-vasopressin acetate; AVP acetate
Forschungsgebiete:  

Neurological Disease Cancer

Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1 .
loading...
    loading...
10
10 Cited Publications
Art. -Nr.: HY-P0202A
CAS. Nr.: 394693-38-0
Synonyms: ET-1 (swine, human) TFA
Target:  

Endothelin Receptor

Forschungsgebiete:  

Cardiovascular Disease

Endothelin 1 (swine, human) (ET-1) TFA is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 TFA acts through two types of receptors ETA and ETB .
loading...
    loading...
7
7 Cited Publications
Art. -Nr.: HY-B1811
CAS. Nr.: 11000-17-2
Synonyms: Arginine vasopressin; Antidiuretic hormone
Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .
loading...
    loading...
4
4 Cited Publications
Art. -Nr.: HY-P1408
CAS. Nr.: 404882-00-4
Target:  

Integrin VEGFR

Forschungsgebiete:  

Cancer

Obtustatin is a non-RGD disintegrin consisting of 41 residues. Obtustatin inhibits the adhesion of α1β1 integrin to type IV Collagen (HY-NP003), blocks α1β1 integrin signaling in endothelial cells, and suppresses FGF2-induced angiogenesis. Obtustatin inhibits tumor progression in mouse models and upregulates VEGF expression in sarcoma-bearing mice. Obtustatin can be used in research related to Lewis lung carcinoma and S-180 sarcoma .
loading...
    loading...
4
4 Cited Publications
Art. -Nr.: HY-P1408A
Target:  

Integrin

Forschungsgebiete:  

Cancer

Obtustatin triacetate is a 41-residue non-RGD disintegrin. Obtustatin triacetate can be isolated from the venom of Vipera lebetina obtusa. Obtustatin triacetate is a potent and selective inhibitor of integrin α1β1 adhesion to type IV collagen. Obtustatin triacetate inhibits angiogenesis and may be used in cancer research .
loading...
    loading...
3
3 Cited Publications
Art. -Nr.: HY-P0090
CAS. Nr.: 47931-85-1
Synonyms: Salmon calcitonin
Target:  

CGRP Receptor

Forschungsgebiete:  

Cancer

Calcitonin salmon, a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption.
loading...
    loading...
3
3 Cited Publications
Art. -Nr.: HY-P1178
CAS. Nr.: 1203586-72-4
Target:  

Trk Receptor p38 MAPK

Forschungsgebiete:  

Neurological Disease

Cyclotraxin B is a BBB-penetrable and selective TrkB inhibitor. Cyclotraxin B inhibits BDNF-induced TrkB activity in a non-competitive manner, with an IC50 of 0.30 nM. Cyclotraxin B has analgesic and anxiolytic effects .
loading...
    loading...
3
3 Cited Publications
Art. -Nr.: HY-A0182
CAS. Nr.: 56-59-7
Synonyms: PLV-2
Target:  

Vasopressin Receptor

Forschungsgebiete:  

Cardiovascular Disease

Felypressin (PLV-2) is a non-catecholamine vasoconstrictor and a vasopressin 1 agonist. Felypressin is widely used in dental procedures .
loading...
    loading...
3
3 Cited Publications
Art. -Nr.: HY-A0182A
CAS. Nr.: 914453-97-7
Synonyms: PLV-2 acetate
Target:  

Vasopressin Receptor

Forschungsgebiete:  

Cardiovascular Disease

Felypressin acetate (PLV-2 acetate) is a non-catecholamine vasoconstrictor and a vasopressin 1 agonist. Felypressin acetate is widely used in dental procedures .
loading...
    loading...
2
2 Cited Publications
Art. -Nr.: HY-P2526
CAS. Nr.: 454487-07-1
Target:  

Complement System

Forschungsgebiete:  

Cancer

LyP-1 is a cyclic 9-amino-acids tumor homing peptide and selectively bind to p32 receptors overexpressed in various tumor-associated cells .
loading...
    loading...
2
2 Cited Publications
Art. -Nr.: HY-P0004
CAS. Nr.: 50-57-7
Synonyms: Lysine vasopressin; [Lys8]-Vasopressin
Lysipressin (Lysine vasopressin ; [Lys8]-Vasopressin ) is a neurohypophyseal nonapeptide with dual cardiovascular regulatory activities of peripheral pressor action and central hypotensive action, and it also regulates pain perception in the body. Lysipressin is an Oxytocin Receptor agonist, with a Ki value of 10.2 nM for porcine OT receptor. Lysipressin stimulates contraction of rabbit bladder smooth muscle via V1-vasopressin receptor. The central hypotensive effect of Lysipressin depends on the sympathetic tone pathway. Lysipressin dose-dependently prolongs tail-flick latency in rats, producing a stable central antinociceptive effect. Lysipressin can be used in studies related to cardiovascular regulation, hypertension and pain .
loading...
    loading...
2
2 Cited Publications
Art. -Nr.: HY-P2526A
Target:  

Peptides

Forschungsgebiete:  

Cancer

LyP-1 TFA is a cyclic 9 amino acids tumor homing peptide and selectively bind to p32 receptors overexpressed in various tumor-associated cells .
loading...
    loading...
2
2 Cited Publications
Art. -Nr.: HY-17584A
CAS. Nr.: 851199-60-5
Target:  

Guanylate Cyclase

Forschungsgebiete:  

Cancer

Linaclotide acetate is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation.
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-P4860
CAS. Nr.: 1802086-30-1
Target:  

Akt Gli JNK PKA

Forschungsgebiete:  

Metabolic Disease

Adropin (34-76) is a secretory domain of Adropin. Adropin (34-76) can inhibit cAMP level and glucose production in hepatocytes, and has a hypoglycemic effect. Adropin (34-76) plays an antifibrotic role by inhibiting the GLI1 signaling pathway .
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-P0204A
Synonyms: Endothelin 3 (Rat,Human) TFA
Forschungsgebiete:  

Neurological Disease

Endothelin-3, human, mouse, rabbit, rat TFA (Endothelin 3 (Rat,Human) TFA) is an adhesion stimulant. Endothelin-3, human, mouse, rabbit, rat TFA stimulates the adhesion of enteric neural crest cells to various ECM components. Endothelin-3, human, mouse, rabbit, rat TFA plays an important role in the maintenance and self-renewal of intestinal progenitor cells, participates in the migration of enteric neural crest cells, and helps maintain a suitable environment for the colonization of enteric neural crest cells. Endothelin-3, human, mouse, rabbit, rat TFA acts synergistically with the β1-integrin signaling pathway during enteric nervous system development. Endothelin-3, human, mouse, rabbit, rat TFA can be used in studies related to distal aganglionosis .
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-P4159
CAS. Nr.: 133972-52-8
Target:  

ERK

Forschungsgebiete:  

Cardiovascular Disease

Endothelin-1 (1-31) (Human) is a potent vasoconstrictor and hypertensive agent. Endothelin-1 (1-31) (Human) is derived from the selective hydrolysis of big ET-1 by chymase .
loading...
    loading...