1 Result for "

DIPG IV cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DIPG IV cells" in MCE Product Catalog:

Cat. No.: HY-145103
CAS No.: 2561494-77-5
Purity:  99.15%
Research Areas:  

Cancer

UNC6934 is a selective NSD2-PWWP1 antagonist with a Kd of 91 nM against human targets. UNC6934 binds to the canonical methyl-lysine binding pocket of NSD2-PWWP1 and directly competes with H3K36me2 for binding. UNC6934 induces the aggregation of NSD2 within the nucleolus, without altering ribosomal RNA transcription, global H3K36me2 levels or the proliferation of KMS-11 cells. UNC6934 can be used in studies related to multiple myeloma and diffuse intrinsic pontine glioma .
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