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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
40 Results for "
DON
" in MedChemExpress (MCE) Product Catalog:
Products (40)
40 Results for "DON" in MCE Product Catalog:
17
17 Cited Publications
Synonyms: L-6-Diazo-5-oxonorleucine; DON
6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity .
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9 Cited Publications
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JHU-083, a proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b + cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals .
Cat. No.: HY-N11678
CAS No.: 131180-21-7
Synonyms: DON-3-β-D-glucoside; Deoxynivalenol 3-glucoside
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Cat. No.: HY-W099547
CAS No.: 2197-63-9
Cat. No.: HY-P991023
CAS No.: 2911590-72-0
Synonyms: 6MW3211
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Cat. No.: HY-N3706
CAS No.: 15297-92-4
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Cat. No.: HY-N6685
CAS No.: 50722-38-8
Synonyms: 3-AcDON; 3-ADON
Cat. No.: HY-179120
CAS No.: 3095661-21-2
ZJS178 is a novel inhibitor of myosin I. ZJS178 is a fungicide that has inhibitory activity against Fusarium graminearum and can reduce DON toxin synthesis. ZJS178 can be used for research on plant diseases such as wheat scab .
Cat. No.: HY-108357R
CAS No.: 157-03-9
Synonyms: L-6-Diazo-5-oxonorleucine (Standard); DON (Standard)
6-Diazo-5-oxo-L-nor-Leucine (Standard) is the analytical standard of 6-Diazo-5-oxo-L-nor-Leucine. This product is intended for research and analytical applications. 6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity[1][2][3].
Cat. No.: HY-178717
CAS No.: 3057478-36-8
WML-01 is a fungicide with EC50s of 0.079, 0.72 and 2.02 μg/mL against F. graminearum, F. fujikuroi and S. sclerotiorum. WML-01 disrupts the cell membrane of F. graminearum and induces deposition of lipid droplets. WML-01 inhibits Deoxynivalenol (DON) (HY-N6684) biosynthesis with no cross-resistance and strongly suppresses ribosomal subunit assembly, impairing protein synthesis. WML-01 effectively controls the fusarium head blight (FHB) epidemic .
Cat. No.: HY-153151
CAS No.: 1998724-98-3
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Fmoc-DON-Boc (Compound 8b) is an Fmoc-protected compound that can be used for the synthesis of proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357). DON is a glutamine antagonist .
Cat. No.: HY-N3371
CAS No.: 77949-42-9
Synonyms: (-)-Longikaurin E
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Cicer arietinum L. Labiatae Terpenoids Other Diseases Diterpenoids Plants Disease Research Fields
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Cat. No.: HY-N3067
CAS No.: 30315-04-9
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Cat. No.: HY-N2726
CAS No.: 355143-38-3
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Catalpa ovata G. Don Iridoids Terpenoids Plants Bignoniaceae
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Cat. No.: HY-N1623
CAS No.: 14103-09-4
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Cat. No.: HY-N11484
CAS No.: 164022-74-6
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Other Terpenoids Catalpa ovata G. Don Monophenols Terpenoids Phenols Plants Bignoniaceae Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-168884
CAS No.: 2713387-11-0
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AV457 is a potent and selective mTOR inhibitor with an IC50 value of 0.54 µM. AV457 inhibits cyst growth in polycystic kidney disease (PKD) organoids. AV457 decreases the protein expression of P-s6, P-p70s6 and don’t decreases the protein expression of P-AKT .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
