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ExoS

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (8) Antibiotic (1) Apoptosis (1) Arf Family GTPase (2) Bacterial (4) Biochemical Assay Reagents (36) Cannabinoid Receptor (5) Cytochrome P450 (1) DNA/RNA Synthesis (7) Drug Derivative (1) Drug Intermediate (1) Drug Metabolite (1) Drug-Linker Conjugates for ADC (3) Endogenous Metabolite (6) Endonuclease (1) Epigenetic Reader Domain (1) Exosomes (2) FLAP (2) Fluorescent Dye (7) Fungal (2) Gli (1) Glycosidase (3) Hedgehog (1) Isotope-Labeled Compounds (1) Microtubule/Tubulin (1) Mitochondrial Metabolism (1) Nucleoside Antimetabolite/Analog (1) Phytohormone (1) PROTAC Linkers (4) Ras (1) Reference Standards (3) Ser/Thr Protease (1) Small Interfering RNA (siRNA) (4) Smo (1) STAT (1) Virus Protease (1) Wnt (2)
By Research Areas:	Cancer (30) Endocrinology (2) Infection (10) Inflammation/Immunology (2) Metabolic Disease (5) Neurological Disease (4)
Click Chemistry:	Labeling and Fluorescence Imaging (5) DBCO (1) PROTAC Synthesis (4) BCN (18)
Oligonucleotides:	Thymine Nucleotide (1) Adenosine (1) Nucleoside Analogs (1) Nucleotide Analogs (1) Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (2) siRNAs (4)

110

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Endosidin-2 2 Publications Verification ES2	Exosomes	Others
Endosidin-2 (ES2) is a selective inhibitor targeting the conserved exosome subunit *EXO70. Endosidin-2 binds to the C-terminal domain of EXO70, inhibiting exocytosis and endosomal recycling, while promoting vacuolar trafficking in plant cells. Endosidin-2 interferes with the EXO70-mediated vesicle-to-plasma membrane anchoring process, leading to abnormal aggregation of auxin transporters (such as PIN2*) in the cytoplasm and redirected to vacuolar degradation, while causing abnormal Golgi structure (such as cup-shaped or ring-shaped vesicles cisternae formation). Endosidin-2 can inhibit exocytosis in plant and mammalian cells and is mainly used to study the dynamic regulation of membrane trafficking (such as polar growth, vesicle sorting) .

Exo1 Maximum Cited Publications 8 Publications Verification	Arf Family GTPase	Others
Exo1 is a chemical inhibitor of the exocytic pathway.

Neuraminidase, Microorganism 1 Publications Verification Exo-α-sialidase	Endogenous Metabolite	Infection
Neuraminidase, Microorganism (Exo-α-sialidase) is an exosialidase, is often used in biochemical studies. Neuraminidase cleaves α-ketosidic linkage between the sialic (N-acetylneuraminic) acid and an adjacent sugar residue. Neuraminidase, derived from mucosal pathogens, is a virulence factor that modifies the host's response to infection .

EXO1-IN-1	Apoptosis	Cancer
EXO1-IN-1 is a human exonuclease 1 (EXO1) inhibitor (IC₅₀ = 15.7 μM). EXO1-IN-1 inhibits DNA end resection, promotes the accumulation of DNA double-strand breaks, and triggers S-phase polyamylation. EXO1-IN-1 induces apoptosis (Apoptosis) in BRCA1-deficient breast cancer cells. EXO1-IN-1 suppresses the growth of BRCA1-deficient breast cancer xenografts. EXO1-IN-1 can be used in research related to BRCA1-deficient breast cancer .

(E)-FOBISIN101	Ser/Thr Protease	Cancer
(E)-FOBISIN101 is a 14-3-3 protein-protein interaction (14-3-3 protein-protein interaction) inhibitor, with IC₅₀ values of 9.3 and 16.4 μM for disrupting the binding of 14-3-3ζ or 14-3-3γ to PRAS40, respectively. (E)-FOBISIN101 inhibits the binding of 14-3-3 to Raf-1 and proline-rich AKT substrate, and neutralizes the ability of 14-3-3 to activate exotoxin S ADP-ribosyltransferase. (E)-FOBISIN101 is applicable to 14-3-3-mediated cancer research .

exo-β-1,4-Xylosidase, Cellulosimicrobium cellulans sp. 21	DNA/RNA Synthesis	Others
Exo-1,4-β-xylosidase is an exonuclease that specifically acts on the β-1,4 glycosidic bonds at the non-reducing ends of xylan and xylooligosaccharides. Exo-1,4-β-xylosidase is Ca ²⁺-dependent and reversibly binds to metal ions to catalyze the hydrolysis of β-1,4 glycosidic bonds, thereby degrading xylan to produce xylose. Exo-1,4-β-xylosidase can be used in research fields such as lignocellulose bioconversion, bioethanol production, and optimization of xylan saccharification processes .

exo-BCN-L-Lysine	PROTAC Linkers	Others
exo-BCN-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. exo-BCN-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

*BCN-exo-PEG3-NH2*	PROTAC Linkers	Cancer
BCN- exo- PEG3- NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN- exo- PEG3- NH2 is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

exo-BCN-NHS carbonate	Biochemical Assay Reagents	Others
exo-BCN-NHS carbonate carbonate contains BCN group. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Exo2	Bacterial	Endocrinology
Exo2 is a secretion inhibitor. Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Exo2 blocks secretory cargo exit from the ER (endoplasmic reticulum) and disrupts the Golgi apparatus, but does not affect the morphology of the TGN (trans-Golgi network) Exo2 can stimulate calcium-dependent exocytosis in permeabilized adrenal chromaff in cells .

APL-1081 Mal-Exo-EVC-MMAE	Drug-Linker Conjugates for ADC Microtubule/Tubulin	Cancer
APL-1081 (Mal-Exo-EVC-MMAE) is part of an antibody-conjugated active molecule (ADC). APL-1081 is conjugated with an ADC linker (peptide Mal-Exo-EEVC) and a potent tubulin polymerization inhibitor, MMAE (HY-15162) .

exo BCN-O-PNB	PROTAC Linkers	Cancer
exo BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . exo BCN-O-PNB is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

*BCN-exo-PEG7-maleimide*	ADC Linker	Cancer
BCN-exo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-exo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

*Coumarin-C2-exo-BCN*	Fluorescent Dye	Others
Coumarin-C2-exoBCN is a dye derivative of Coumarin (HY-N0709). Coumarin-C2-exoBCN contains the lyophilic bidentate macrocyclic ligand exo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to generate stable triazoles under catalyst-free conditions.

*BCN-exo-PEG3-maleimide*	ADC Linker	Cancer
BCN-exo-PEG3-maleimide is an ADC Linker containing 3 PEG units. BCN-exo-PEG3-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which enables the further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

AH-D peptide TFA	Exosomes Virus Protease	Infection Cancer
AH-D peptide TFA is an antiviral peptide that selectively disrupts membrane structures within the size range of exosomes, inducing T-EXO depletion and enhancing cancer immunotherapy .

exo-IWR-1	Wnt	Infection Cancer
exo-IWR-1, an inactive stereoisomer of Endo-IWR-1, is a negative control of IWR-1 (HY-12238). IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway .

Inulinase	Biochemical Assay Reagents	Others
Inulinase is expressed in various microorganisms, including yeasts, fungi, mesophilic bacteria. Inulinase can be used to produce inulooligosaccharides from inulin and inulin-containing materials. Inulinase produced by yeast has hydrolysing capability towards sucrose, inulin, levan type fructans exo-wise .

MU1409	Endonuclease	Cancer
MU1409 is an inhibitor of MRE11 nuclease with an IC₅₀ of 12.1 μM. Additionally, MU1409 also inhibits FEN1 and *EXO1, with IC₅₀* values of 24.2 and 176.4 μM, respectively. MU1409 affects DNA repair in cells, preventing the degradation of stalled replication forks in BRCA2-deficient cells, making it a promising candidate for research on BRCA2 mutation-induced cancers .

N-3-Hydroxybutyryl-L-homoserine lactone 3-OH-C4-HSL; N-3-Hydroxybutanoyl-L-homoserine lactone; N-3-Hydroxybutyryl-L-HSL	Bacterial	Infection
N-3-Hydroxybutyryl-L-homoserine lactone (3-OH-C4-HSL) is an acyl-homoserine lactone, that can be isolated from Vibrionaceae. N-3-Hydroxybutyryl-L-homoserine lactone is a signaling molecule that is involved in bacterial quorum sensing (QS). N-3-Hydroxybutyryl-L-homoserine lactone senses the density of bacterial population, regulates the cellular process, such as bioluminescence, biofilm formation, and exo-enzyme production .

APL-1091 Mal-Exo-EEVC-MMAE	Drug-Linker Conjugates for ADC	Cancer
APL-1091 (Mal-Exo-EEVC-MMAE) is part of a Drug-linker conjugate for ADC. APL-1091 contains a Mal-Exo-EEVC (HY-169353) linker and MMAE (HY-15162) (Microtubule inhibitor). APL-1091 can be used for ADC synthesis .

*BCN-exo-PEG2-maleimide*	ADC Linker	Cancer
BCN-exo-PEG2-maleimide is an ADC Linker containing 2 PEG units. BCN-exo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

DBCO-Dextran sulfate (MW 40000)	Drug Intermediate	Inflammation/Immunology
DBCO-Dextran sulfate (MW 40000) can be used to construct DS-EXOs in cells via click chemistry, that can be used for the research of rheumatoid arthritis (RA) .

FEN1-IN-8	FLAP	Cancer
FEN1-IN-8 (compund 15) is a selective FEN1 inhibitor, with IC₅₀ values of < 100 nM for FEN1 and 100 nM to 1 μM for *EXO1*, respectively. FEN1-IN-8 can be used for study of colorectal cancer and gastric cancer .

CAY10731	Fluorescent Dye	Others
CAY10731 (compound 3) is a highly selective fluorescent probe for detection of hydrogen sulfide (H₂S). CAY10731 is used to monitor exo- and endogenous H₂S in both cancer and normal cells. CAY10731 is applied for imaging of H₂S in living tissues at variable depths and in nematodes .

exo-α-Glucosidase, Bacteroides thetaiotaomicron	Glycosidase	Others
exo-α-Glucosidase,Bacteroides thetaiotaomicron (EC.3.2.1.20) is a α-Glucosidase. exo-α-Glucosidase, using maltose as a donor, exhibits excellent transglycosidic activity towards various receptors .

*FastTaq DNA Polymerase(5'→3' exo-)*	DNA/RNA Synthesis Biochemical Assay Reagents	Others
FastTaq DNA Polymerase (5'→3' exo-) is a modified DNA polymerase based on Taq DNA Polymerase. FastTaq DNA Polymerase (5'→3' exo-) lacks the 5'→3' exonuclease activity of wild-type Taq. It retains the 5'→3' DNA polymerase activity of wild-type Taq .

exo-α-Fucosidase, Bacteroides fragilis	Biochemical Assay Reagents	Others
exo-α-Fucosidase, Bacteroides fragilis (EC 3.2.1.51) is a glycoside hydrolase that would release free fucose .

exo-β-1,4-xylosidase, Bacteroides ovatus	DNA/RNA Synthesis	Others
exo-β-1,4-xylosidase, Bacteroides ovatus (EC.3.2.1.37) is an exonuclease that specifically acts on the β-1,4 glycosidic bonds at the non-reducing ends of xylan and xylooligosaccharides. exo-β-1,4-xylosidase is Ca ²⁺-dependent and reversibly binds to metal ions to catalyze the hydrolysis of β-1,4 glycosidic bonds, thereby degrading xylan to produce xylose. exo-β-1,4-xylosidase can be used in research fields such as lignocellulose bioconversion, bioethanol production, and optimization of xylan saccharification processes .

exo-β-1,4-xylosidase, Clostridium stercorarium	DNA/RNA Synthesis	Others
exo-β-1,4-xylosidase,Clostridium stercorarium (EC.3.2.1.37) is an exonuclease that specifically acts on the β-1,4 glycosidic bonds at the non-reducing ends of xylan and xylooligosaccharides. exo-β-1,4-xylosidase is Ca ²⁺-dependent and reversibly binds to metal ions to catalyze the hydrolysis of β-1,4 glycosidic bonds, thereby degrading xylan to produce xylose. exo-β-1,4-xylosidase can be used in research fields such as lignocellulose bioconversion, bioethanol production, and optimization of xylan saccharification processes .

Oxazepine	Hedgehog Antibiotic	Infection Cancer
Oxazepine (compound 4a) has antimicrobial viability via binding OMPA/ exo-1,3-beta-glucanase proteins. Oxazepine is a hedgehog signaling inhibitor with antitumor viability .

exo-BCN-Fmoc-L-Lysine	PROTAC Linkers	Others
exo-BCN-Fmoc-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. exo-BCN-Fmoc-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

*Mal-Exo-EEVC*	ADC Linker	Cancer
Mal-Exo-EEVC is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) .

*Mal-Exo-EVC*	ADC Linker	Cancer
Mal-Exo-EVC is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) .

*BCN-exo-PEG4-NHS*	ADC Linker	Cancer
BCN-exo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-exo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.

*BCN-exo-PEG8-NHS*	ADC Linker	Cancer
BCN-exo-PEG8-NHS is an ADC Linker containing 8 PEG units. BCN-exo-PEG8-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.

exo-α-Fucosidase, Elizabethkingia meningoseptica	Biochemical Assay Reagents	Others
exo-α-Fucosidase, Elizabethkingia meningoseptica (EC 3.2.1.51) is a glycoside hydrolase that would release free fucose .

exo-α-Fucosidase, Emticicia oligotrophica	Biochemical Assay Reagents	Others
exo-α-Fucosidase, Emticicia oligotrophica (EC 3.2.1.51) is a glycoside hydrolase that would release free fucose .

exo-α-1,2-Fucosidase, Bifidobacterium bifidum	Biochemical Assay Reagents	Others
exo-α-1,2-Fucosidase,Bifidobacterium bifidum is a glycoside hydrolase that would release free fucose .

*BCN-exo-PEG2-NH2*	ADC Linker	Cancer
BCN-exo-PEG2-NH2 is an ADC Linker containing 2 PEG units. BCN-exo-PEG2-NH2 contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.

*Cy5-PEG2-exo-BCN*	Fluorescent Dye	Others
Cy5-PEG2-exo-BCN is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 2 PEG units. Cy5-PEG2-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.

DHGA5 exo-16,17-Dihydro-gibberellin A5-13-acetate	Phytohormone	Others
DHGA5 (exo-16,17-Dihydro-gibberellin A5-13-acetate) is a GA3β-hydroxylase (OsGA3ox2) inhibitor. DHGA5 inhibits Arabidopsis root growth with an IC₅₀ of 97 μM. DHGA5 also suppresses the elongation of rice second leaf sheath. DHGA5 can alleviate oxidative damage to Arabidopsis seedlings under NaCl salt stress and reduce the accumulation of superoxide anion .

APL-1092 Mal-Exo-EEVC-Exatecan	Drug-Linker Conjugates for ADC	Cancer
APL-1092 (Mal-Exo-EEVC-Exatecan) is a drug-linker conjugate for ADC, which contains Exatecan (HY-13631) (ADC payload) and a linker .

exo-α-1,3-Mannosidase, Bacteroides thetaiotaomicron	Biochemical Assay Reagents	Others
exo-α-1,3-Mannosidase, Bacteroides thetaiotaomicron is a glycoside hydrolase that can hydrolyze mannose α-1,3 linkages in host N-glycans .

endo-α-1,5-Arabinanase, Bacteroides thetaiotaomicron	Biochemical Assay Reagents	Others
endo-α-1,5-Arabinanase, Bacteroides thetaiotaomicron (EC.3.2.1.99) is a glycoside hydrolase involved in arabinan decomposition. exo-α-1,5-Arabinanase is capable of cleaving arabinan main chains .

endo-α-1,5-Arabinanase, Bacillus subtilis 168	Biochemical Assay Reagents	Others
endo-α-1,5-Arabinanase, Bacillus subtilis 168 (EC.3.2.1.99) is a glycoside hydrolase involved in arabinan decomposition. exo-α-1,5-Arabinanase is capable of cleaving arabinan main chains .

Cat. No.	Product Name	Type

HY-156305

*Coumarin-C2-exo-BCN*	Fluorescent Dye
Coumarin-C2-exoBCN is a dye derivative of Coumarin (HY-N0709). Coumarin-C2-exoBCN contains the lyophilic bidentate macrocyclic ligand exo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to generate stable triazoles under catalyst-free conditions.

HY-D1275

CAY10731	Fluorescent Dye
CAY10731 (compound 3) is a highly selective fluorescent probe for detection of hydrogen sulfide (H₂S). CAY10731 is used to monitor exo- and endogenous H₂S in both cancer and normal cells. CAY10731 is applied for imaging of H₂S in living tissues at variable depths and in nematodes .

HY-149620

*Cy5-PEG2-exo-BCN*	Fluorescent Dye
Cy5-PEG2-exo-BCN is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 2 PEG units. Cy5-PEG2-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-D2120A

*Cy3-PEG3-exo-BCN*	Fluorescent Dye
Cy3-PEG3-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-D2149

*Cy5-PEG7-exo-BCN*	Fluorescent Dye
Cy5-PEG7-exo-BCN is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG7-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-D2121A

*Cy3-PEG7-exo-BCN*	Fluorescent Dye
Cy3-PEG7-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-155327A

*Cy3-PEG2-exo-BCN*	Fluorescent Dye
Cy3-PEG2-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

Cat. No.	Product Name	Type

HY-112624H

Dextran T2 (MW 2,000)

Dextran 2; Dextran D2; Dextran T2(MW 1600-2400)

Biochemical Assay Reagents

Dextran T2 (Dextran 2; Dextran T2(MW 1600-2400)) is a natural high molecular weight polysaccharide, the glycosidic bonds in its structure can be recognized by endo-dextranase and exo-dextranase. Dextran T2 (MW 2,000) breaks the glycosidic bonds in the enzymatic hydrolysis mechanism, releasing products such as D-glucose, Isomaltose (IM₂), and Isomaltotriose (IM₃). Dextran T2 (MW 2,000) can be used as a model substrate to characterize the catalytic properties of dextranase (such as optimal pH, temperature and product specificity), and to study enzymatic mechanism research and polysaccharide degradation pathways in glycobiology. The Dextran series of compounds are also a natural polysaccharide drug carrier, which can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity .

Cat. No.	Product Name	Target	Research Area

HY-P10862A

AH-D peptide TFA	Exosomes Virus Protease	Infection Cancer
AH-D peptide TFA is an antiviral peptide that selectively disrupts membrane structures within the size range of exosomes, inducing T-EXO depletion and enhancing cancer immunotherapy .

Cat. No.	Product Name

HY-KE8010

Exonuclease I
This product is obtained by expressing the Exo I gene (E. coli) in Escherichia coli and then purifying and isolating it multiple times.

Host:	Rabbit (2)
Reactivity:	Human (2) Rat (1) Mouse (1) Zebrafish (1)
Application:	IHC-P (1) WB (2)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (2) Recombinant (2)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P87056

	RRP42 Antibody (YA6749) EAP1 antibody; ExoS7_HUMAN antibody; ExoSc7 antibody; ExoSome complex component RRP42 antibody; ExoSome complex exonuclease RRP42 antibody; ExoSome component 7 antibody; FLJ26543 antibody; hRrp42p antibody; KIAA0116 antibody; p8 antibody; EAP1 antibody; ExoS7_HUMAN antibody; ExoSc7 antibody; ExoSome complex component RRP42 antibody; ExoSome complex exonuclease RRP42 antibody; ExoSome component 7 antibody; FLJ26543 antibody; hRrp42p antibody; KIAA0116 antibody; p8 antibody; Ribosomal RNA processing protein 42 antibody; Ribosomal RNA-processing protein 42 antibody; RRP42 antibody; Rrp42p antibody;	WB, IHC-P	Human, Zebrafish
	RRP42 Antibody (YA6749) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RRP42.

HY-P86869

	EXOSC9 Antibody (YA6562) Autoantigen PM/Scl 1 antibody; ExoS9_HUMAN antibody; ExoSC 9 antibody; ExoSC9 antibody; ExoSome complex component RRP45 antibody; ExoSome complex exonuclease RRP45 antibody; ExoSome component 9 antibody; p5 antibody; p6 antibody; P75 polymyositis scleroderma overlap syndrome associated autoantigen antibody; Autoantigen PM/Scl 1 antibody; ExoS9_HUMAN antibody; ExoSC 9 antibody; ExoSC9 antibody; ExoSome complex component RRP45 antibody; ExoSome complex exonuclease RRP45 antibody; ExoSome component 9 antibody; p5 antibody; p6 antibody; P75 polymyositis scleroderma overlap syndrome associated autoantigen antibody; P75 polymyositis-scleroderma overlap syndrome-associated autoantigen antibody; PM/Scl 75 antibody; PM/Scl-75 antibody; PMSCL autoantigen 75kD antibody; PMSCL1 antibody; Polymyositis/scleroderma autoantigen 1 75kDa antibody; Polymyositis/scleroderma autoantigen 1 antibody; Polymyositis/scleroderma autoantigen 75 kDa antibody; RRP45 antibody; Rrp45p antibody;	WB	Human, Mouse, Rat
	EXOSC9 Antibody (YA6562) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to EXOSC9.

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Cat. No.	Product Name		Classification

HY-W754588

exo-BCN-L-Lysine		BCN PROTAC Synthesis
exo-BCN-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. exo-BCN-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-133402

*BCN-exo-PEG3-NH2*		BCN PROTAC Synthesis
BCN- exo- PEG3- NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN- exo- PEG3- NH2 is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W096149

exo-BCN-NHS carbonate		BCN
exo-BCN-NHS carbonate carbonate contains BCN group. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-133406

exo BCN-O-PNB		BCN PROTAC Synthesis
exo BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . exo BCN-O-PNB is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-134734

*BCN-exo-PEG7-maleimide*		BCN
BCN-exo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-exo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

HY-156305

*Coumarin-C2-exo-BCN*		Labeling and Fluorescence Imaging BCN
Coumarin-C2-exoBCN is a dye derivative of Coumarin (HY-N0709). Coumarin-C2-exoBCN contains the lyophilic bidentate macrocyclic ligand exo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to generate stable triazoles under catalyst-free conditions.

HY-156322

*BCN-exo-PEG3-maleimide*		BCN
BCN-exo-PEG3-maleimide is an ADC Linker containing 3 PEG units. BCN-exo-PEG3-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which enables the further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

HY-156320

*BCN-exo-PEG2-maleimide*		BCN
BCN-exo-PEG2-maleimide is an ADC Linker containing 2 PEG units. BCN-exo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

HY-164416

DBCO-Dextran sulfate (MW 40000)		DBCO
DBCO-Dextran sulfate (MW 40000) can be used to construct DS-EXOs in cells via click chemistry, that can be used for the research of rheumatoid arthritis (RA) .

HY-157052

exo-BCN-Fmoc-L-Lysine		PROTAC Synthesis BCN
exo-BCN-Fmoc-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. exo-BCN-Fmoc-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-156323

*BCN-exo-PEG4-NHS*		BCN
BCN-exo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-exo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-156324

*BCN-exo-PEG8-NHS*		BCN
BCN-exo-PEG8-NHS is an ADC Linker containing 8 PEG units. BCN-exo-PEG8-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-156319

*BCN-exo-PEG2-NH2*		BCN
BCN-exo-PEG2-NH2 is an ADC Linker containing 2 PEG units. BCN-exo-PEG2-NH2 contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-149620

*Cy5-PEG2-exo-BCN*		Labeling and Fluorescence Imaging BCN
Cy5-PEG2-exo-BCN is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 2 PEG units. Cy5-PEG2-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-D2120A

*Cy3-PEG3-exo-BCN*		Labeling and Fluorescence Imaging BCN
Cy3-PEG3-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-D2149

*Cy5-PEG7-exo-BCN*		BCN
Cy5-PEG7-exo-BCN is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG7-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-D2121A

*Cy3-PEG7-exo-BCN*		BCN Labeling and Fluorescence Imaging
Cy3-PEG7-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-155327A

*Cy3-PEG2-exo-BCN*		Labeling and Fluorescence Imaging BCN
Cy3-PEG2-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-183628

MEAP 2-(4-Morpholinoanilino-6-[(2-exo-norbornyl) amino)-purine		BCN
MEAP (2-(4-Morpholinoanilino-6-[(2-exo-norbornyl) amino)-purine) is a NEDD9-STAT3 modulator. MEAP disrupts NEDD9-STAT3 interaction, driving STAT3 Y705 dephosphorylation. MEAP induces G₂/M phase arrest. MEAP can be used for the research of anaplastic thyroid cancer .

Cat. No.	Product Name		Classification

HY-W011725

N-6-Methyl-2-deoxyadenosine m6dA		Nucleoside Analogs Adenosine
N-6-Methyl-2-deoxyadenosine (m6dA) is an adenine nucleoside analogue. N-6-Methyl-2-deoxyadenosine targets nuclear processes and DNA replication machineries including WER, SATB1, TFAM, Jumu, SSBP1, DNA polymerase η and phage polymerase *Gp90 exo* ⁻**. N-6-Methyl-2-deoxyadenosine acts as a multifunctional epigenetic regulator that modulates transcription, DNA damage response, cell cycle, transposon silencing, stress adaptation, epigenetic crosstalk, and nucleosome organization in both prokaryotes and eukaryotes. N-6-Methyl-2-deoxyadenosine regulates mitochondrial epigenetic inheritance and is required for fear extinction memory in mice. N-6-Methyl-2-deoxyadenosine exhibits dysregulated levels in cancers. N-6-Methyl-2-deoxyadenosine can be used for the research of glioblastoma, triple negative breast cancer, and conditioned fear (fear extinction impairment) .

HY-RS04586

EXO5 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
EXO5 Human Pre-designed siRNA Set A contains three designed siRNAs for EXO5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS04585

EXO1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
EXO1 Human Pre-designed siRNA Set A contains three designed siRNAs for EXO1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS27243

Exo1 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Exo1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Exo1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS20731

Exo1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Exo1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Exo1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-185274

3'-O-(2-Nitrobenzyl)-dTTP		Nucleotide Analogs Thymine Nucleotide
3'-O-(2-Nitrobenzyl)-dTTP acts as a reversible terminator for DNA chain elongation. 3'-O-(2-Nitrobenzyl)-dTTP interacts with 9°N polymerase (exo-) A485L/Y409V, gets recognized and incorporated into the elongating DNA chain, thereby temporarily terminating the polymerase reaction. 3'-O-(2-Nitrobenzyl)-dTTP carries a 3'-O-(2-nitrobenzyl) blocking group, which can be removed by laser irradiation to regenerate the free 3'-OH ⁻ group and restore polymerase activity. 3'-O-(2-Nitrobenzyl)-dTTP is applicable in DNA sequencing studies .

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