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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
465 Results for "
Fungicides
" in MedChemExpress (MCE) Product Catalog:
Products (465)
465 Results for "Fungicides" in MCE Product Catalog:
9
9 Publications Verification
Referencia número: HY-P0027
No. CAS: 102396-24-7
Category:
Antifungal Marine natural products Disease Research Other Antibiotics Infection Monophenols Animals Antibiotics Cyclopeptides Phenols Sponge Anticancer Disease Research Fields
Target:
6
6 Cited Publications
Target:
Carbendazim is a potent and orally active broad-spectrum benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria, Fusarium and Sclerotina . Carbendazim is a benzimidazole (HY-Y1825) derivative with antitumor activity and used for cancer research, especially advanced solid tumors and lymphoma .
5
5 Cited Publications
Referencia número: HY-B1858
No. CAS: 50512-35-1
Áreas de investigación:
Isoprothiolane is a blast fungicide with antifungal, anti-inflammatory and insecticidal activities. Isoprothiolane primarily acts on fungi during the penetration and growth stages of infecting hyphae. Isoprothiolane can be used as an insecticide, pesticide, etc. In addition, Isoprothiolane can reduce serum phospholipid and total lipid concentrations, regulating lipid metabolism. Isoprothiolane is also used in the research of fatty liver .
5
Target:
4
Áreas de investigación:
Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases .
4
4 Cited Publications
Referencia número: HY-B1460
No. CAS: 61318-91-0
Synonyms: (±)-Sulconazole mononitrate
Sulconazole mononitrate ((±)-Sulconazole mononitrate), an imidazole derivative, is a broad-spectrum fungicide. Sulconazole mononitrate can be used for the research of dermatomycoses, pityriasis versicolor, and cutaneous candidiasis .
4
4 Cited Publications
Synonyms: Tiabendazole; 2-(4-Thiazolyl)benzimidazole
Target:
Environmental Pollutants Mitochondrial Metabolism Parasite Caspase VEGFR MDM-2/p53 CDK Interleukin Related
Áreas de investigación:
Infection Cardiovascular Disease Inflammation/Immunology Cancer
Thiabendazole is an orally available benzimidazole fungicide with repellent and anticancer activities. Thiabendazole can result in developmental malformations. Thiabendazole can be used for modeling .
3
3 Cited Publications
Referencia número: HY-B0842
No. CAS: 23564-05-8
Target:
Environmental Pollutants Fungal Apoptosis Bcl-2 Family Caspase TNF Receptor SOD Reactive Oxygen Species (ROS)
Áreas de investigación:
Thiophanate-Methyl is a pesticide residue and fungicide. Thiophanate-Methyl induces hepatotoxicity via caspase-3-mediated apoptosis and oxidative stress, thereby causing metabolic imbalance in the liver of zebrafish. Thiophanate-Methyl impairs the rhizobacteria-mediated defense response of cucumber against fusarium wilt .
3
3 Cited Publications
Referencia número: HY-B0849
No. CAS: 131860-33-8
Target:
Environmental Pollutants Reactive Oxygen Species (ROS) Fungal Apoptosis Bacterial Phosphatase
Áreas de investigación:
Azoxystrobin is an orally active, broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis .
3
3 Cited Publications
Referencia número: HY-N12257
No. CAS: 27220-57-1
Category:
3
3 Cited Publications
Referencia número: HY-B0850
No. CAS: 119446-68-3
Target:
Áreas de investigación:
Difenoconazole is a sterol demethylation inhibitor, as a fungicide. Difenoconazole binds the heme portion of the fungal cytochrome P450 51, interferes the mycelial growth and inhibits the spore germination of pathogens, suppressing fungal growth .
3
3 Cited Publications
Referencia número: HY-B0848
No. CAS: 41814-78-2
Target:
Áreas de investigación:
Tricyclazole is a pentaketone melanin biosynthesis inhibitor and a unique fungicide for controlling rice blast. Tricyclazole alters the structure and function of fungal cell walls, reduces fungal pathogenicity and penetration, and causes dose-dependent liver damage in animals .
3
3 Cited Publications
Referencia número: HY-B0852
No. CAS: 107534-96-3
Áreas de investigación:
Tebuconazole is an orally active agricultural azole fungicide which can also inhibit CYP51 with IC50s of 0.9 and 1.3 μM for Candida albicans CYP51 (CaCYP51) and truncated Homo sapiens CYP51 (Δ60HsCYP51), respectively. Tebuconazole induces lipid accumulation and oxidative stress in HepG2 Cells. Tebuconazole decreases MAC-T cells viability and proliferation, induces ER-stress-mediated apoptosis and increases oxidative stress levels in MAC-T cells .
2
2 Cited Publications
Referencia número: HY-N6626
No. CAS: 175013-18-0
Áreas de investigación:
Pyraclostrobin is a highly effective and broad-spectrum strobilurin fungicide. Pyraclostrobin can induce oxidative DNA damage, mitochondrial dysfunction and autophagy through the activation of AMPK/mTOR signaling. Pyraclostrobin can be used to control crop diseases .
2
2 Cited Publications
Referencia número: HY-B0847
No. CAS: 60207-90-1
Áreas de investigación:
Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals .
2
2 Cited Publications
Synonyms: 2-Aminothiazole; 2-Thiazolylamine
Target:
Áreas de investigación:
Aminothiazole (2-Aminothiazole), a typical heterocyclic amine, is a precursor for the synthesis of biologically active molecules including sulfur agents, biocides, fungicides, antibiotics, dyes and chemical reaction accelerators .
1
1 Cited Publications
Referencia número: HY-B0843
No. CAS: 57837-19-1
Target:
Áreas de investigación:
Metalaxyl is a fungicide agent that inhibits the protein synthesis in fungi. Metalaxyl against downy mildews and soil-borne diseases by Phytium ssp. and Phytophthora ssp. .
1
1 Cited Publications
Target:
Áreas de investigación:
Epoxiconazole, a fungicide, is a demethylation inhibitor of the Ergosterol biosynthesis pathway. Epoxiconazole exhibits strong inhibitory effects on both carbendazim-resistant and phenamacril-resistant isolates, and can be used for controlling many crop diseases .
1
1 Cited Publications
Áreas de investigación:
Penconazole is a typical triazole fungicide, and mainly applied on apples, grapes, and vegetables to control powdery mildew. Penconazole inhibits sterol biosynthesis in fungi. Penconazole decrease AChE activity in the cerebrum and cerebellum of rats .
1
1 Cited Publications
Referencia número: HY-B2051
No. CAS: 55335-06-3
Target:
Áreas de investigación:
Triclopyr, a foliar systemic herbicide and fungicide, is widely used for broadleaf and woody plant control. Triclopyr has severe toxicity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
