1 Result for "

GS-CHO cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GS-CHO cells" in MCE Product Catalog:

Cat. No.: HY-P992381

Target:  

Drug Derivative

Research Areas:  

Cancer

IBI352g4a is a humanized IgG1 monoclonal antibody targeting PVRIG (Kd = 0.53 nM) and acts as a PVRIG/PVRL2 inhibitor. The anti-tumor effect of IBI352g4a depends on the binding of its Fc region to FcγR. IBI352g4a binds to the extracellular domains of human and cynomolgus monkey PVRIG, and blocks the PVRIG-PVRL2 interaction. IBI352g4a induces NK cell activation, promotes their degranulation and tumor killing. IBI352g4a can be used in the research of gastric cancer .
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