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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
148 Results for "
IIA
" in MedChemExpress (MCE) Product Catalog:
Products (148)
148 Results for "IIA" in MCE Product Catalog:
62
62 Publications Verification
Synonyms: Sodium heparin; Sodium heparinate
Heparin sodium salt (Sodium heparin) is an anticoagulant which binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa. Heparin sodium salt significantly inhibits exosome-cell interactions.
40
Category:
Quinones Terpenoids Samanea saman (Jacq.) Merr. Diterpenoids Plants Disease Research Fields Naphthalene Quinones Cancer Labiatae Extract
Target:
22
19
10
Target:
Research Areas:
Varespladib (LY315920) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM. Varespladib exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively .
10
10 Cited Publications
Synonyms: LY315920 sodium
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Research Areas:
Varespladib sodium (LY315920 sodium) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM. Varespladib sodium exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively .
9
7
7 Cited Publications
Cat. No.: HY-N1370
CAS No.: 69659-80-9
Synonyms: Sodium Tanshinone IIA sulfonate; Tanshinone IIA sodium sulfonate; Sulfotanshinone sodium; Sulfotanshinone IIA sodium
Category:
Terpenoids Samanea saman (Jacq.) Merr. Diterpenoids Plants Disease Research Fields Cancer Labiatae Extract
Target:
5
Category:
Terpenoids Samanea saman (Jacq.) Merr. Diterpenoids Plants Disease Research Fields Cancer Labiatae Extract
Target:
3
3 Cited Publications
Synonyms: Sodium heparin (MW 15kDa); Sodium heparinate (MW 15kDa)
Research Areas:
Heparin sodium salt (MW 15kDa) (Sodium heparin (MW 15kDa)) is a polymer of Heparin with the molecular weight of 15kDa. Heparin sodium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa .
3
3 Cited Publications
Cat. No.: HY-P74628
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PLA2G2A; Non-Pancreatic Secretory Phospholipase A2; Prev. PLA2B; Phospholipase A2; Prev. PLA2L; RASF-A; Phosphatidylcholine 2-Acylhydrolase 2A; PLA2S; Phospholipase A2, Membrane Associated; PLAS1; Group IIA Phospholipase A2; SPLA2; GIIC SPLA2; MOM1; Phosp
Species:
Mouse
Source:
P. pastoris
2
2 Cited Publications
Cat. No.: HY-N6686
CAS No.: 21411-53-0
Synonyms: Pristinamycin IIA; Ostreogrycin A
Category:
Infection Microorganisms Macrolide Antibiotics Antibiotics Disease Research Antibacterial Disease Research Fields
Target:
2
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-P80445
Synonyms: Alpha CaMKII; Calcium calmodulin dependent protein kinase II; Calcium/calmodulin dependent protein kinase II alpha B subunit; Calcium/calmodulin dependent protein kinase type II alpha chain; Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; Calcium/calmodulin-dependent protein kinase II alpha; Calcium/calmodulin-dependent protein kinase II-alpha; Calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase type IIA; CaM kinase II alpha chain; CaM kinase II alpha subunit; CaM kinase II subunit alpha; CaMK II alpha subunit; CaMK-II subunit alpha; Camk2a; CAMKA; CaMKII; CaMKIINalpha; EC2.7.11.17; KCC2A_HUMAN; KIAA0968; MGC123320; MGC139375; MGC155201; mKIAA0968; PK2CDD; PKCCD; R74975; zgc:112538; zgc:123320;
1
1
1 Cited Publications
Synonyms: CHDI00390576
CHDI-390576, a potent, cell permeable and CNS penetrant class IIa histone deacetylase (HDAC) inhibitor with IC50s of 54 nM, 60 nM, 31 nM, 50 nM for class IIa HDAC4, HDAC5, HDAC7, HDAC9, respectively, shows >500-fold selectivity over class I HDACs (1, 2, 3) and ~150-fold selectivity over HDAC8 and the class IIb HDAC6 isoform .
1
Research Areas:
Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Enoxaparin (PK 10169), a low-molecular-weight heparin (LMWH) derivative. Enoxaparin exerts anticoagulant activity through antithrombin III, an endogenous inhibitor of factor Xa and thrombin IIa. Enoxaparin protect the rat hippocampus against TBI (traumatic brain injury) via antioxidant and anti-inflammatory properties. Enoxaparin can be used for the research of deep vein thrombosis (DVT), pulmonary embolism, TBI and COVID-19 .
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1
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1
1 Cited Publications
Cat. No.: HY-P70231
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: F9; Autoprothrombin IIA; Coagulation Factor IX; Coagulant Factor IX; FIX; Christmas Disease; Plasma Thromboplastic Component; Hemophilia B; Plasma Thromboplastin Component; Factor IX F9; Christmas Factor; Factor IX; PTC; Factor 9; Truncated Coagulation Fa
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
