1 Result for "

KBV20C cells

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "KBV20C cells" in MCE Product Catalog:

Cat. No.: HY-155784
CAS No.: 2170274-53-8
Research Areas:  

Cancer

SPC-180002 is a SIRT1/3 dual inhibitor, with IC50 values of 1.13 and 5.41 μM, respectively. SPC-180002 disturbs redox homeostasis via ROS generation, which leads to an increase in both p21 protein stability and mitochondrial dysfunction. SPC-180002 strongly inhibits cell cycle progression and cancer cell growth. SPC-180002 activates the Nrf2 signaling pathway .
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