Search Result
Results for "
Lithium
" in MedChemExpress (MCE) Product Catalog:
45
Biochemical Assay Reagents
9
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-Y0649
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- HY-44076
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LAP
4 Publications Verification
Lithium phenyl-2,4,6-trimethylbenzoylphosphinate
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Biochemical Assay Reagents
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Others
Cancer
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LAP (Lithium phenyl-2,4,6-trimethylbenzoylphosphinate) is a free radical initiator. The free radicals produced by LAP under bioprinting conditions are potentially cytotoxic and mutagenic. In addition, the concentration of LAP affects the mechanical strength of 3D printed scaffolds. Generally, the concentration range of LAP used for curing is 0.05%-1%. The elastic modulus produced at a concentration of 0.1% is the highest, with enhanced mechanical properties and excellent biocompatibility .
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- HY-113071A
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MVA Lithium salt
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Endogenous Metabolite
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Cardiovascular Disease
Neurological Disease
Metabolic Disease
Cancer
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Mevalonic acid (MVA) lithium salt is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid lithium salt is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid lithium salt can be used in studies of myopathy and heart failure .
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- HY-136408
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- HY-Y0649D
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Environmental Pollutants
Biochemical Assay Reagents
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Others
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Lithium chloride, for molecular biology, 99% can be used in the preparation of wash buffers for chromatin immunoprecipitation. Lithium chloride, for molecular biology, 99% is a kind of biological materials or organic compounds that are widely used in life science research .
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- HY-128730
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Endogenous Metabolite
Bacterial
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Metabolic Disease
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Acetyl phosphate lithium potassium is an endogenous metabolic product. Acetyl phosphate lithium potassium is a key substance in bacterial metabolic regulation, particularly in Lysine acetylation, and plays an important role in bacterial responses to environmental stress and adaptive reactions .
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- HY-Y0292
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- HY-113128A
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Endogenous Metabolite
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Metabolic Disease
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sn-Glycerol 3-phosphate lithium is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate lithium from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate lithium for lipid metabolism .
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- HY-W099535
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Biochemical Assay Reagents
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Others
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Lithium dodecyl sulfate is an anionic hydrocarbon surfactant with both surface tension reduction and interfacial adsorption capabilities. Lithium dodecyl sulfate induces low surface viscosity; it forms micelles in aqueous solutions through entropy-driven (low temperature) and enthalpy-driven (high temperature) mechanisms. When acting synergistically with tetrabutylammonium bromide, Lithium dodecyl sulfate exhibits cloud point behavior due to micelle aggregation and phase separation. Lithium dodecyl sulfate can form an adsorption layer at the air-water interface with quantifiable surface excess and minimum area per molecule, and it has higher equilibrium surface tension and foamability compared to other dodecyl sulfate counterion variants. The foam stability of Lithium dodecyl sulfate above its critical micelle concentration is low, and its dynamic surface tension pattern changes dynamically with bubble frequency .
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- HY-17567B
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- HY-W094474
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hydrate/monohydrateortrihydrate
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GSK-3
Apoptosis
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Infection
Neurological Disease
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Lithium chloride hydrate, an orally active mood stabilizer, is a potent virus inhibitor and effective immunomodulatory agent. Lithium chloride hydrate has antidepressant activity by inhibiting GSK3β and promoting neurogenesis. Lithium chloride hydrate alleviates cognition dysfunction and the symptoms of acute mania and depression. Lithium chloride hydrate can also be used for research of virus infection and Alzheimer's disease .
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- HY-130777A
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Adenylyl imidodiphosphate Lithium hydrate
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Drug Derivative
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Metabolic Disease
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AMP-PNP (Adenylyl imidodiphosphate) lithium hydrate is a non-hydrolyzable ATP analog. AMP-PNP lithium hydrate binds to ATP binding sites competely but is not hydrolyzed by enzymes, providing stable experimental conditions for studying ATP-dependent processes. AMP-PNP lithium hydrate can also be used to study enzyme activity, kinase regulation, DNA/RNA metabolism, ion channel function, and protein complex assembly .
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- HY-134427
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Palmitoyl CoA Lithium
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Endogenous Metabolite
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Metabolic Disease
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Palmitoyl coenzyme A lithium is an acyl-CoA thioester that can be transported into the mitochondrial matrix via the carnitine shuttle system and is involved in β-oxidation. Palmitoyl coenzyme A lithium can also be used as a substrate for sphingosine biosynthesis .
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- HY-A0256B
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- HY-137167
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Gpp(NH)p Lithium
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Adenylate Cyclase
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Metabolic Disease
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Guanylyl imidodiphosphate lithium (Gpp (NH) p lithium) is a non-hydrolyzable GTP analog. Guanylyl imidodiphosphate lithium increases adenylate cyclase activity. Guanylyl imidodiphosphate lithium binds to and irreversibly activates G proteins .
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- HY-W250174
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3,5-Diiodosalicylic acid Lithium salt
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Biochemical Assay Reagents
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Others
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Lithium 3,5-diiodosalicylate is a compound used in the study of bipolar disorder and other psychiatric disorders. It contains lithium and a salicylate. Lithium 3,5-diiodosalicylate works by affecting the levels of certain neurotransmitters in the brain, including dopamine and serotonin.
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- HY-112540A
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Endogenous Metabolite
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Metabolic Disease
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Acetoacetic acid lithium is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Acetoacetic acid lithium induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes. Acetoacetic acid lithium can be used to study metabolic diseases .
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- HY-W108875
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BRL-4910A Lithium; Pseudomonic acid Lithium
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Antibiotic
Bacterial
Aminoacyl-tRNA Synthetase
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Infection
Endocrinology
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Mupirocin lithium is an antibiotic. Mupirocin lithium inhibits bacterial isoleucyl-tRNA synthetase, blocking protein synthesis. Mupirocin lithium has high activity against Gram-positive bacteria such as Staphylococcus and Streptococcus, as well as some Gram-negative bacteria (such as Haemophilus influenzae). Mupirocin lithium can be used in the research of diseases such as skin infections (such as MRSA infections) and chronic sinusitis .
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- HY-113596A
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Acetyl-CoA Lithium
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Oxidative Phosphorylation
Endogenous Metabolite
Autophagy
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Cardiovascular Disease
Metabolic Disease
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Acetyl-coenzyme A (Acetyl-CoA) lithium is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A lithium, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A lithium is also a key precursor of lipid synthesis .
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- HY-W007531
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Biochemical Assay Reagents
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Others
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2-Fluoro-5-iodopyridine is an electrolyte additive. 2-Fluoro-5-iodopyridine can not only effectively protect the anode by forming a stable SEI film, but also convert dead lithium into active lithium. 2-Fluoro-5-iodopyridine effectively improves the performance of lithium metal batteries .
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- HY-134891
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(E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate Lithium
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Nuclear Factor of activated T Cells (NFAT)
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Infection
Inflammation/Immunology
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HMBPP lithium is an intermediate in isoprenoid biosynthesis that can be produced by bacteria and protozoa that use the non-mevalonate pathway for isoprenoid biosynthesis. HMBPP lithium is a ligand of the internal domain of BTN3A1 and is an activator for human Vγ9/Vδ2 T cells. HMBPP lithium exhibits phagostimulant property in mosquitos .
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- HY-B1295
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Litarex tetrahydrate
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Apoptosis
Endogenous Metabolite
Bacterial
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Infection
Cardiovascular Disease
Metabolic Disease
Inflammation/Immunology
Cancer
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Lithium citrate (Litarex) tetrahydrate is a natural preservative and food tartness enhancer. Lithium citrate tetrahydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Lithium citrate tetrahydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Lithium citrate tetrahydrate is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .
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- HY-134421
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HMG-CoA Reductase (HMGCR)
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Metabolic Disease
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2-Butenoyl coenzyme A lithium is an inactivator and a substrate of Plasmodium falciparum enoyl-β-hydroxyacyl-acyl carrier protein (ACP) reductase and other enoyl-CoA reductases, and it is also the lithium salt of trans-2-methyl-2-butenoyl coenzyme A. 2-Butenoyl coenzyme A lithium acts on short-chain and medium-chain coenzyme A dehydrogenases as well as glutaryl-CoA dehydrogenase, and shows no activity against wild-type isovaleryl-CoA dehydrogenase. 2-Butenoyl coenzyme A lithium functions as a metabolite in the L-isoleucine catabolic pathway, and can serve as a substrate in the activity assay of 3-ketothiolase. 2-Butenoyl coenzyme A lithium is applicable to research related to 3-ketothiolase deficiency .
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- HY-126833A
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Endogenous Metabolite
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Infection
Cancer
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Myristoyl coenzyme A lithium is lithium-labeled myristoylated coenzyme A (CoA). Myristoylation is an essential process in viruses and is generally controlled by N-myristoyltransferase (NMT). And NMT is more active in colon epithelial tumors than in normal cells. Reduced Ccoenzyme A (CoA) is known to be a key regulator of NMT activity, whereas oxidized CoA does not allow NMT to promote myristoylation. Myristoyl coenzyme A blocks the demyristoylation process and has potential anticancer and antiviral mechanisms .
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- HY-134424
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Endogenous Metabolite
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Metabolic Disease
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Propionyl coenzyme A lithium, a coenzyme A derivative of propionic acid, is an important metabolic intermediate formed by the thioester bond between coenzyme A and propionic acid. The breakdown and production of Propionyl coenzyme A lithim is important for the metabolism of organisms .
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- HY-W094471
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Biochemical Assay Reagents
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Others
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Lithium acetate dihydrate is a compound with a one-dimensional structure that has various applications in industries such as pharmaceuticals, ceramics, and research laboratories. Lithium acetate dihydrate is often used as a source of lithium ions in chemical reactions and as a precursor in the synthesis of other lithium compounds .
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- HY-141474
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Biochemical Assay Reagents
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Others
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Glutaryl coenzyme A lithium is an important endogenous metabolites. Glutaryl coenzyme A lithium can be used in HMG-CoA or Glutaryl-CoA related experiment.
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- HY-115062
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Phospholipase
NADPH Oxidase
p38 MAPK
Akt
NF-κB
AP-1
Reactive Oxygen Species (ROS)
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Cardiovascular Disease
Inflammation/Immunology
Cancer
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MJ-33 lithium salt is a competitive phospholipase A2 (PLA2) inhibitor with an IC50 of 0.3 μM. MJ-33 lithium salt inhibits NOX2 activation and reduces ROS production by blocking the PLA2 activity of Prdx6. MJ-33 lithium salt effectively inhibits the activity of acidic PLA2 (pH 4.0) and reduces the degradation of alveolar surfactant phosphatidylcholine (PC), but exerts no effect on alkaline PLA2 (pH 8.5). MJ-33 lithium salt significantly alleviates lung oxidative injury induced by ischemia-reperfusion (I/R). MJ-33 lithium salt significantly inhibits the invasion, migration and adhesion abilities of prostate cancer cells by suppressing the MAPK, AKT, NF-κB and AP-1 signaling pathways. MJ-33 lithium salt can be used for the research of ROS-related diseases and prostate cancer .
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- HY-W250153
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P2Y Receptor
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Cardiovascular Disease
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Adenosine 3'-phosphate 5'-phosphosulfate lithium, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
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- HY-W337739
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Monopotassium L-glutamate
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Biochemical Assay Reagents
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Others
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L-Glutamic acid monopotassium salt is a food additive and flavor enhancer that can reduce the harmful effects of lithium .
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- HY-W010479
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- HY-109591A
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Oleoyl-CoA Lithium
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Endogenous Metabolite
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Others
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Oleoyl coenzyme A (Oleoyl-CoA) lithium is a thioester of oleic acid and coenzyme A. Oleoyl coenzyme A lithium has a role as an Escherichia coli metabolite and a mouse metabolite .
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- HY-D0884
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(S)-2-Hydroxypropanoic acid Lithium
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Biochemical Assay Reagents
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Others
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L-Lactic acid lithium is a lithium salt of L-Lactic acid (HY-Y0479) with certain bioconductive properties. L-Lactic acid can be used as a precursor for the production of bioplastic polymer polylactic acid .
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- HY-126912A
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Biochemical Assay Reagents
Endogenous Metabolite
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Others
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Lauroyl coenzyme A lithium salt is an intermediary in fatty acid synthesis or metabolism, formed by combining long-chain fatty acids (or lauric acid) with coenzyme A. Lauroyl coenzyme A lithium salt is involved in lipid biosynthesis and fatty acid transport, in which coenzyme A acts as a transport molecule to help move and target specific compounds.
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- HY-21170B
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Triflate Lithium; Trifluoromethylsulfonate Lithium; Trifluoromethanesulphonic acid Lithium
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Biochemical Assay Reagents
Herbicide
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Others
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Trifluoromethanesulfonate (Triflate;Trifluoromethylsulfonate) lithium is a stable lithium salt and dopant with four resonance states, which is commonly used as an electrolyte component in polymer light-emitting electrochemical cells and primary lithium batteries. Trifluoromethanesulfonate lithiumalso acts as a catalyst for the preparation of the herbicide Imazapyr. In MEH-PPV-based light-emitting electrochemical cells, Trifluoromethanesulfonate lithium promotes electrochemical p-type doping at the anode interface under applied bias, thereby facilitating the formation of p-i-n junctions, exciton generation, and light emission. Trifluoromethanesulfonate lithiumexhibits strong ion pairing in non-aqueous electrolytes, but its electrochemical stability window is narrower than that of lithium bistrifluoromethylsulfonyl imidee .
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- HY-W250163
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NAD+ lithium
Maximum Cited Publications
44 Publications Verification
β-DPN Lithium; β-NAD Lithium; β-Nicotinamide Adenine Dinucleotide Lithium
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Biochemical Assay Reagents
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Metabolic Disease
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NAD+ lithium (β-DPN lithium) is a lithium salt of nicotinamide adenine dinucleotide. NAD+ is a coenzyme in the REDOX reaction. NAD+ can directly or indirectly affect several key cellular functions, including metabolic pathways, DNA repair, chromatin remodeling, cell aging, and immune cell function .
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- HY-W010625
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Biochemical Assay Reagents
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Neurological Disease
Inflammation/Immunology
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Lithium 2-hydroxypropanoate is a lithium salt. Lithium 2-hydroxypropanoate has immunomodulatory activity (slightly enhancing PHA (HY-N7038)-induced lymphocyte proliferation). Lithium 2-hydroxypropanoate can be used in antioxidant activity assays. Lithium 2-hydroxypropanoate can be used in the research of mental diseases .
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- HY-160596
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5-Formyl-deoxycytidine Lithium
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DNA/RNA Synthesis
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Others
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5-Formyl-dCTP (5-Formyl-deoxycytidine) lithium is a DCTPP1 substrate. 5-Formyl-dCTP lithium acts as a mutagen/epigenetic disruptor via DNA polymerase incorporation, mutagenic mispairings, and disturbed epigenetic programming. 5-Formyl-dCTP lithium can be used for research on genotoxicity .
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- HY-W094464
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- HY-134423S
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Isotope-Labeled Compounds
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Others
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Stearoyl coenzyme A- 13C18 (lithium) is the 13C labeled Stearoyl coenzyme A lithium . Stearoyl coenzyme A (Stearoyl-CoA) lithium is an active compound that can be used as a substrate for the determination of stearoyl-Coenzyme desaturase in microsomes .
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- HY-W099571
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Stearic acid Lithium; Lithium octadecanoate
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Environmental Pollutants
Biochemical Assay Reagents
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Others
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Lithium stearate (Stearic acid (lithium)) is a compound that forms vesicles in reaction with silver nitrate, thereby changing the reaction kinetics of the nucleation and self-assembly process of silver stearate. It has the activity that even in the presence of excess silver nitrate, only about 80% can be converted into silver stearate and the residual lithium stearate will inhibit the growth process of silver stearate crystals, thereby producing silver stearate crystals that are much smaller than those obtained from sodium stearate, providing an opportunity to further control the self-assembly and crystal growth of silver stearate.
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- HY-113499B
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Drug Metabolite
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Others
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cis-Malonylcarnitine lithium is an ester compound and a metabolite of Malonyl CoA (HY-115899). The level of cis-Malonylcarnitine lithium is closely related to some diseases, such as malonic aciduria, non-syndromic cleft lip with or without cleft palate, etc .
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- HY-113005A
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Endogenous Metabolite
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Metabolic Disease
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Glutarylcarnitine lithium is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes .
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- HY-113304A
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Endogenous Metabolite
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Metabolic Disease
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(S)-3,4-Dihydroxybutyric acid lithium hydrate, a normal human urinary metabolite, is a β-oxidation metabolite of γ-hydroxybutyrate. (S)-3,4-Dihydroxybutyric acid lithium hydrate can be used for research on succinic semialdehyde dehydrogenase deficiency .
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- HY-179170S
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- HY-N11409A
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Herbicide
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Others
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Shikimate-3-phosphate lithium is the salt form of Shikimate-3-phosphate. Shikimate-3-phosphate lithium is a central microbial, parasite and plant metabolite, as a product of the shikimate kinase-catalysed reaction. Shikimate-3-phosphate lithium serves as an enzyme substrate for 5-enolpyruvoyl-shikimate 3-phosphate synthase, which is a target of anti-infectives and of herbicides .
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- HY-B1680
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Litarex
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Biochemical Assay Reagents
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Neurological Disease
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Lithium citrate is a lithium supplement that reduces excess brain N-acetylaspartate (NAA) in Canavan disease. Canavan disease is an autosomal recessive leukodystrophy caused by mutations in the aspartate acylase (ASPA) gene, which catalyzes the hydrolysis of N-acetylaspartate (NAA) to acetate and aspartate .
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- HY-134428
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Endogenous Metabolite
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Metabolic Disease
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Arachidonoyl coenzyme A lithium is an unsaturated fatty acyl coenzyme A, formed by the condensation of the thiol group of coenzyme A with the carboxyl group of arachidonic acid .
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- HY-147064
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Fructose-1,6-bisphosphate aldolase
Others
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Others
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DL-4-Hydroxy-2-ketoglutarate lithium is the substrate of 4-hydroxy-2-oxoglutarate aldolase (HOGA). DL-4-Hydroxy-2-ketoglutarate lithium can be cleaved by HOGA to produce pyruvate and glyoxylate .
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- HY-14654A
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- HY-128036D
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2',3'-Dideoxyadenosine 5'-triphosphate Lithium
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DNA/RNA Synthesis
HIV
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Infection
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ddATP (lithium) (2',3'-Dideoxyadenosine 5'-triphosphate (lithium)) is an active metabolite of 2',3'-dideoxyinosine and a DNA polymerase chain elongation inhibitor. ddATP (lithium) is used in Sanger DNA sequencing and in research related to viral infection [1][2][3][4][5].
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- HY-W841438
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Amyloid-β
Tau Protein
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Neurological Disease
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Lithium orotate is an orally active lithium supplement with reduced binding that can bypass amyloid sequestration in AD mice models. Lithium orotate can prevent Aβ plaque deposition and phospho-tau accumulation and reverse AD pathology, neuroinflammatory changes and memory loss in AD mice models and ageing wild-type mice. Lithium orotate can be used for the research of alcoholism and Alzheimer’s disease .
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- HY-N0216A
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Bacterial
Fungal
Endogenous Metabolite
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Others
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Benzoic acid lithium is an aromatic alcohol found in many plants and is a common additive in food, beverages, cosmetics and other products. Benzoic acid lithium inhibits bacteria and fungi and acts as a preservative .
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- HY-W250153A
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P2Y Receptor
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Cardiovascular Disease
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Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
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- HY-W726667A
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(R)-Citramalate Lithium; (2R)-Methylmalic acid Lithium
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Drug Isomer
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Neurological Disease
Metabolic Disease
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(R)-(-)-Citramalic acid ((R)-Citramalate) lithium, a lithium salt of Citramalic acid, is the R enantiomer of Citramalic acid lithium. (R)-(-)-Citramalic acid lithium is involved in the metabolism of glutamate through the methylaspartate pathway. (R)-(-)-Citramalic acid lithium is promising for research of neurological disorders .
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- HY-113013A
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β-Hydroxypyruvic acid Lithium hydrate; 3-Hydroxypyruvic acid Lithium hydrate
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Endogenous Metabolite
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Metabolic Disease
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Hydroxypyruvic acid lithium hydrate (β-Hydroxypyruvic acid lithium hydrate) is an intermediate in the metabolism of glycine, serine and threonine. Hydroxypyruvic acid lithium hydrate is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. Hydroxypyruvic acid lithium hydrate is involved in the metabolic disorder which is the dimethylglycine dehydrogenase deficiency pathway.
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- HY-W108875R
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BRL-4910A Lithium (Standard); Pseudomonic acid Lithium (Standard)
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Antibiotic
Bacterial
Reference Standards
Aminoacyl-tRNA Synthetase
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Infection
Endocrinology
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Mupirocin (lithium) (Standard) is the analytical standard of Mupirocin lithium (HY-W108875). This product is intended for research and analytical applications. Mupirocin lithium is an antibiotic. Mupirocin lithium inhibits bacterial isoleucyl-tRNA synthetase, blocking protein synthesis. Mupirocin lithium has high activity against Gram-positive bacteria such as Staphylococcus and Streptococcus, as well as some Gram-negative bacteria (such as Haemophilus influenzae). Mupirocin lithium can be used in the research of diseases such as skin infections (such as MRSA infections) and chronic sinusitis .
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- HY-113071AR
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MVA Lithium salt (Standard)
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Reference Standards
Endogenous Metabolite
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Cardiovascular Disease
Neurological Disease
Metabolic Disease
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Mevalonic acid lithium salt (Standard) is the analytical standard of Mevalonic acid lithium salt. This product is intended for research and analytical applications. Mevalonic acid (MVA) lithium salt is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid lithium salt is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid lithium salt can be used in studies of myopathy and heart failure .
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- HY-166297
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- HY-B1128B
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Cephamandole Lithium
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Antibiotic
Bacterial
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Infection
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Cefamandole (Cephamandole) lithium is a semi-synthetic second-generation cephalosporin antibiotic with broad-spectrum antimicrobial activity. Cefamandole lithium is resistant to hydrolysis by β-lactamases produced by some Gram-negative bacteria. Cefamandole lithium kills Gram-positive cocci and various Gram-negative bacilli mainly by inhibiting cell wall synthesis, but it is inactive against Pseudomonas, Proteus vulgaris and Providencia stuartii, and its efficacy is affected by inoculum size. The plasma elimination half-life of Cefamandole lithium in rats is only 0.4 h, it is mainly excreted in urine in biologically active form, and it hardly penetrates the non-inflamed blood-brain barrier. Cefamandole lithium is widely used in studies related to bacterial infections .
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- HY-139099A
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Gp3G Lithium
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DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
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Cancer
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Diguanosine 5′-triphosphate (Gp3G) lithium is a dinucleoside triphosphates. Diguanosine 5′-triphosphate lithium also is a virus-specific oligonucleotide. Diguanosine 5′-triphosphate lithium is needed for the synthesis of RNA during the transcription process .
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- HY-135024A
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Phenylacetyl coenzyme A Lithium; S-Benzeneacetate-CoA Lithium; S-Benzeneacetate-coenzyme A Lithium
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Endogenous Metabolite
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Metabolic Disease
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Phenylacetyl CoA lithium (Phenylacetyl Coenzyme A lithium) is an acceptor oxidoreductase. Phenylacetyl CoA is a membrane-bound molybdenum–iron–sulfur enzyme involved in anaerobic metabolism of phenylalanine in the denitrifying bacterium Thauera aromatica .
|
-
- HY-100714D
-
|
2-APV Lithium; DL-2-Amino-5-phosphonovaleric acid Lithium
|
iGluR
|
Neurological Disease
Inflammation/Immunology
|
|
DL-AP5 (2-APV) lithium is a competitive NMDA (N-methyl-D-aspartate) receptor antagonist. DL-AP5 lithium shows significantly antinociceptive activity. DL-AP5 lithium specifically blocks on channels in the rabbit retina .
|
-
- HY-A0256BR
-
-
- HY-134422
-
|
Isobutyryl CoA Lithium
|
Biochemical Assay Reagents
|
Others
|
|
Isobutyryl coenzyme A (Isobutyryl CoA) lithium is A coenzyme A involved in the metabolic pathway of fatty acids. Isobutyryl coenzyme A lithium is made by combining isobutyric acid (short chain branched fatty acid) with coenzyme A.
|
-
- HY-137782B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Palmitoleoyl-CoA lithium is the lithium salt form of Palmitoleoyl-CoA (HY-137782). Palmitoleoyl-CoA lithium can be activated and transported into the mitochondria for metabolism, specifically for β-oxidation. Palmitoleoyl-CoA lithium induces the cardiac mitochondrial membrane permeability transition, which causes mitochondrial dysfunction. Palmitoleoyl-CoA lithium regulates metabolism via allosteric control of AMPK β1-isoforms .
|
-
- HY-113013C
-
|
β-Hydroxypyruvic acid Lithium; 3-Hydroxypyruvic acid Lithium
|
Biochemical Assay Reagents
|
Others
|
|
Hydroxypyruvic acid (β-Hydroxypyruvic acid; 3-Hydroxypyruvic acid) lithium is a biochemical assay reagent.
|
-
- HY-137674B
-
-
- HY-144166S
-
-
- HY-142080A
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Pimeloyl-CoA lithium is a biotin precursor of Escherichia coli. Pimeloyl-CoA lithium can be used for the research of the pathway of de novo biotin biosynthesis in Escherichia coli .
|
-
- HY-112540AR
-
|
|
Endogenous Metabolite
Reference Standards
|
Metabolic Disease
|
|
Acetoacetic acid (lithium) (Standard) is the analytical standard of Acetoacetic acid (lithium). This product is intended for research and analytical applications. Acetoacetic acid lithium is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Acetoacetic acid lithium induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes. Acetoacetic acid lithium can be used to study metabolic diseases .
|
-
- HY-B0122A
-
|
McN 4853 Lithium; RWJ 17021 Lithium
|
iGluR
GABA Receptor
Sodium Channel
Calcium Channel
Potassium Channel
Carbonic Anhydrase
|
Neurological Disease
|
|
Topiramate (McN 4853) lithium is a broad-spectrum antiepileptic agent. Topiramate lithium is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase .
|
-
- HY-155743A
-
|
2',3'-Dideoxyuridine-5'-triphosphate Lithium
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
ddUTP (lithium), 100 mM in H2O is a nucleotide analog that can be incorporated into DNA, RNA, or other nucleic acids. ddUTP (lithium), 100 mM in H2O can be used to prepare DNA/RNA hybridization experiments, such as Southern blots and Northern blots.
|
-
- HY-166326
-
-
- HY-127154
-
|
|
Fluorescent Dye
|
Others
|
|
Carmine lithium is a natural red colorant, which belongs to the coccid dye family .
|
-
- HY-B1295R
-
|
Litarex tetrahydrate (Standard)
|
Apoptosis
Endogenous Metabolite
Bacterial
Reference Standards
|
Infection
Cardiovascular Disease
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Lithium citrate (tetrahydrate) (Standard) is the analytical standard of Lithium citrate (tetrahydrate). This product is intended for research and analytical applications. Lithium citrate (Litarex) tetrahydrate is a natural preservative and food tartness enhancer. Lithium citrate tetrahydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Lithium citrate tetrahydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Lithium citrate tetrahydrate is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .
|
-
- HY-10713
-
|
|
GlyT
|
Neurological Disease
|
|
Org-24598 lithium is an inhibitor of glycine transporter 1 GlyT-1 . Org-24598 lithium can inhibit the specific binding of [ 3H] CHIBIA-3007 to the rat brain membranes with a Ki value of 16.9 nM .
|
-
- HY-134423
-
|
Stearoyl-CoA Lithium
|
Biochemical Assay Reagents
|
Others
|
|
Stearoyl coenzyme A (Stearoyl-CoA) lithium is an active compound that can be used as a substrate for the determination of stearoyl-Coenzyme desaturase in microsomes .
|
-
- HY-119810A
-
|
Ucb 44212 Lithium
|
HIV
|
Neurological Disease
|
|
Seletracetam (Ucb 44212) lithium, as an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy .
|
-
- HY-109591S
-
|
Oleoyl-CoA-13C18 Lithium
|
Isotope-Labeled Compounds
|
Others
|
|
Oleoyl coenzyme A- 13C18 (lithium) is the 13C labeled Oleoyl Coenzyme A lithium . Oleoyl coenzyme A (Oleoyl-CoA) is a thioester of oleic acid and coenzyme A. Oleoyl coenzyme A has a role as an Escherichia coli metabolite and a mouse metabolite .
|
-
- HY-119810B
-
-
- HY-W744370
-
-
- HY-201283A
-
-
- HY-176078
-
|
|
Adrenergic Receptor
|
Others
|
|
4-Hydroxy xylazine O-glucuronide (lithium) is a metabolite of the α2-adrenergic receptor agonist xylazine. 4-Hydroxy xylazine O-glucuronide (lithium) can be synthesized from xylazine via the intermediate metabolite 4-hydroxy xylazine .
|
-
- HY-143953S
-
-
- HY-138877A
-
|
|
Phosphatase
|
Cancer
|
|
Phosphoglycolic acid (lithium) is a competitive inhibitor of phosphoglycerate mutase (PGAM)-B, an enzyme of the glycolytic pathway. Phosphoglycolic acid increases basal and fMLF-induced levels of G6P in intact neutrophils. Phosphoglycolic acid thereby increases upstream intermediates in neutrophils, thereby amplifying the respiratory oxidative burst .
|
-
- HY-134425
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
β-Methylcrotonyl coenzyme A lithium is an intermediate in leucine metabolism and can be used as a substrate to study the specificity and kinetics of β-methylcrotonyl coenzyme A carboxylase (MCCase) .
|
-
- HY-B1681
-
|
Salicylic acid Lithium; 2-Hydroxybenzoic acid Lithium
|
Tau Protein
|
Neurological Disease
|
|
Lithium salicylate (Salicylic acid lithium) is an orally active lithium salt. Lithium salicylate (Salicylic acid lithium) attenuates tau phosphorylation, mitigates associated pathologies in Alzheimer’s mice. Lithium salicylate (Salicylic acid lithium) can be used for Alzheimer’s research .
|
-
- HY-W543739
-
|
|
MOFs
|
Others
|
|
Lithium4-vinylbenzenesulfonate is a metal-organic framework (MOF).
|
-
- HY-150172A
-
|
ITP Lithium salt; Inosine triphosphate Lithium salt
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Inosine-5'-triphosphate (ITP) lithium salt is a nucleotide analogue that acts on multiple G proteins. Inosine-5'-triphosphate lithium salt can bind to the α -subunit of G proteins and participate in G protein-mediated signal transduction as a substitute for GTP. Inosine-5'-triphosphate lithium salt interacts with the nucleotide-binding site of the G protein α -subunit, affecting the activity and function of G proteins. Inosine-5'-triphosphate lithium salt is used to explore the role of the G protein signaling pathway in cellular physiological and pathological processes .
|
-
- HY-115736B
-
-
- HY-113005AR
-
|
|
Endogenous Metabolite
Reference Standards
|
Metabolic Disease
|
|
Glutarylcarnitine (lithium) (Standard) is the analytical standard of Glutarylcarnitine (lithium). This product is intended for research and analytical applications. Glutarylcarnitine lithium is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes .
|
-
- HY-123014A
-
|
|
Leukotriene Receptor
|
Inflammation/Immunology
|
|
SC-45694 (lithium) is an analog of LTB4. SC-45694 (lithium) exhibits an agonist activity against LTB4 for chemotaxis and an antagonist activity against LTB4-induced degranulation. SC-45694 (lithium) stimulates neutrophil chemotaxis .
|
-
- HY-Z4763A
-
-
- HY-178589A
-
-
- HY-141479B
-
|
Butyryl CoA Lithium hydrate
|
Drug Intermediate
|
Others
|
|
Butyryl-Coenzyme A (Butyryl CoA) lithium hydrate is a short-chain acyl CoA that can synthesize Butyric acid (HY-B0350) .
|
-
- HY-W707802
-
-
- HY-CE01268
-
-
- HY-W552257A
-
|
|
Drug Intermediate
|
Others
|
|
Hydroxypyruvic acid phosphate lithium serves as a crucial metabolic intermediate in the biosynthesis of L-Serine (HY-N0650), being formed from the conversion of the glycolytic intermediate 3-phosphoglycerate through the action of 3-phosphoglycerate dehydrogenase.
|
-
- HY-172731
-
-
- HY-134426
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
DL-β-Hydroxybutyryl coenzyme A lithium is an intermediate in the fermentation of butyric acid and the metabolism of lysine and tryptophan, and is produced from β-hydroxybutyric acid by short-chain-CoA synthase .
|
-
- HY-W010479R
-
|
|
Reference Standards
Biochemical Assay Reagents
Drug Intermediate
|
Others
|
|
Propane sultone (Standard) is the analytical standard of Propane sultone (HY-W010479). This product is intended for research and analytical applications. Propane sultone is a multifunctional intermediate, which can be used for the synthesis of other active compounds. Propane sultone can also be used as an additive in lithium battery electrolytes .
|
-
- HY-129944A
-
|
|
Phospholipase
|
Inflammation/Immunology
|
|
MJ33-OH lithium is a metabolite of MJ33. MJ33 is an active-site-directed, specific, competitive, and reversible phospholipase A2 (PLA2) inhibitor. MJ33 blocks the calcium-independent phospholipase A2 (iPLA2) activity of Prdx6 .
|
-
- HY-15648D
-
|
|
Histone Demethylase
|
Cancer
|
|
GSK-J1 lithium salt is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC50 of 60 nM towards KDM6B.
|
-
- HY-40145
-
|
|
Drug Intermediate
|
Others
|
|
1-Boc-3-iodoazetidine acts as a bifunctional additive for lithium-oxygen (Li-O2) batteries and can be used to enhance the performance of Li-O2 batteries. 1-Boc-3-iodoazetidine is applied in the synthesis of C3-functionalized azetidines and C2-functionalized azetidines via a lithium/iodine exchange or β-elimination/lithiation reaction sequence .
|
-
- HY-114293S
-
|
Acetyl-CoA-13C2 Lithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
Autophagy
Oxidative Phosphorylation
|
Metabolic Disease
|
|
Acetyl coenzyme A- 13C2 lithium is the 13C-labeled Acetyl coenzyme A (HY-114293). Acetyl-coenzyme A (Acetyl-CoA) is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A is also a key precursor of lipid synthesis .
|
-
- HY-135582S1
-
|
|
Isotope-Labeled Compounds
Estrogen Receptor/ERR
|
Endocrinology
|
|
Raloxifene 4'-glucuronide-d4 (lithium) is deuterium labeled Raloxifene 4'-glucuronide. Raloxifene 4'-glucuronide is a primary metabolite of Raloxifene. Raloxifene 4'-glucuronide formation is mediated mostly by UGT1A10 and UGT1A8. Raloxifene 4'-glucuronide binds to estrogen receptor with an IC50 of 370 μM. . Raloxifene is a selective estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression .
|
-
- HY-135581S1
-
|
|
Isotope-Labeled Compounds
Estrogen Receptor/ERR
|
Endocrinology
|
|
Raloxifene 6-glucuronide-d4 (lithium) is deuterium labeled Raloxifene 6-glucuronide. Raloxifene 6-glucuronide is a primary metabolite of Raloxifene. Raloxifene 6-glucuronide is mediated mostly by UGT1A1 and UGT1A8. Raloxifene 6-glucuronide binds to estrogen receptor with an IC50 of 290 μM. Raloxifene is a selective and nonsteroidal estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression .
|
-
- HY-107205
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Propargyl methacrylate is an effective electrolyte additive used to stabilize the formation of the solid electrolyte interface (SEI) layer on meso-porous carbon microbeads (MCMB) in lithium-ion batteries .
|
-
- HY-Y0643
-
|
Pivaloyloxymethyl chloride
|
Biochemical Assay Reagents
Drug Intermediate
|
Others
|
|
Pivaloyloxymethyl chloride is an intermediate. Pivaloyloxymethyl chloride can be used in the synthesis of Compound 8b. Compound 8b can stimulate the production of interferon gamma .
|
-
- HY-W017850
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1,5,2,4-Dioxadithiane 2,2,4,4-tetraoxide is a sulfur-containing electrolyte additive that can be used to prepare graphite/NMC111 lithium-ion cells .
|
-
- HY-W016693
-
-
- HY-Y1005
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Triammonium phosphate trihydrate interacts with the magnesium ions to form a precipitate, which can be used for magnesium separation from lithium in salt-lake brines .
|
-
- HY-21190
-
|
|
Drug Intermediate
|
Others
|
|
Perfluorobutylsulfonyl fluoride is a four-carbon polyfluorinated sulfonyl fluoride. Perfluorobutylsulfonyl fluoride serves as an intermediate that can be used for the synthesis of other compounds .
|
-
- HY-111525
-
|
|
Oxidative Phosphorylation
Bacterial
Antibiotic
|
Infection
|
|
Monactin is a mactrotetralide antibiotic and a non-selective ionophore for monovalent cations, including potassium, sodium, and lithium. Monactin is isolated from Streptomyces and has antiproliferative activity .
|
-
- HY-103232
-
|
|
mGluR
|
Neurological Disease
|
IEM-1925 bromide is an orally active glutamate receptor antagonist, increases the latent period and decreases the duration of status epilepticus in rats in a lithium-pilocarpine model of epilepsy .
|
-
- HY-Y0109
-
|
Pyrazin-2-yl chloride
|
Drug Intermediate
|
Others
|
|
Chloropyrazine (Pyrazin-2-yl chloride) is a pyrazine compound that can be used for the synthesis of active compounds. Chloropyrazine can also serve as an electrolyte additive for research on lithium-sulfur batteries .
|
-
- HY-Y0109R
-
|
|
Drug Intermediate
Reference Standards
|
Others
|
|
Chloropyrazine (Pyrazin-2-yl chloride) is a pyrazine-based compound that can be used for the synthesis of active compounds. Additionally, Chloropyrazine can be used as an electrolyte additive in the research of lithium-sulfur batteries .
|
-
- HY-Y1810
-
|
|
Environmental Pollutants
Biochemical Assay Reagents
|
Others
|
|
Diethylene glycol diethyl ether is an electrolyte solvent for a non-aqueous lithium-air cell. Diethylene glycol diethyl ether can facilitate the reversible reduction and oxidation processes at the porous carbon electrode without a catalyst .
|
-
- HY-160610A
-
|
|
Drug Derivative
|
Others
|
|
Carbamoyl phosphate dilithium salt is an antisickling agent and plays a significant role in the urea cycle. Carbamoyl phosphate dilithium salt carbamylates the amino-terminal valine residues of hemoglobin S in erythrocytes, which interferes with the sickling phenomenon. Carbamoyl phosphate dilithium salt exhibits toxicity due to the lithium cation .
|
-
- HY-W010751
-
|
2,3,4,6-Tetrakis-O-(phenylmethyl)-D-glucopyranose
|
Drug Intermediate
|
Others
|
|
2,3,4,6-Tetra-O-benzyl-D-glucopyranose is a glucose derivative that serves as an important intermediate in the synthesis of complex glycoconjugates, oligosaccharides, and glycosylated drug molecules .
|
-
- HY-107771R
-
|
MCW-2 (Standard)
|
Reference Standards
Parasite
|
Cancer
|
|
Propane sultone (Standard) is the analytical standard of Propane sultone. This product is intended for research and analytical applications. Propane sultone is a versatile intermediate. Propane sultone is utilized as an additive in the electrolyte in lithium battery. Propane sultone combines with cellulose and carbohydrate, that can be used in sizing, printing and textile. Propane sultone is utilized in dye manufacture .
|
-
- HY-W105310A
-
|
Nacr
|
HDAC
Sirtuin
CDK
Bcl-2 Family
Apoptosis
|
Others
|
|
Croconic acid disodium (Nacr) is a lysine crotonylation (Kcr) activator and electroactive material. Croconic acid disodium reduces the expression of HDAC2, HDAC3, SIRT1, and SIRT3, and increases the expression of EP300, CITED1, ACSS2, DPF2, CDYL, MLLT3, and YEATS2. Croconic acid disodium elevates intracellular crotonyl-CoA content and global histone lysine crotonylation levels. Croconic acid disodium promotes the growth of bovine fibroblasts, regulates cell cycle progression, and inhibits bovine fibroblast apoptosis (apoptosis). Croconic acid disodium improves the blastocyst development efficiency of bovine somatic cell nuclear transfer embryos. Croconic acid disodium undergoes reversible lithium intercalation/deintercalation reactions via sodium-lithium ion exchange. Croconic acid disodium is applicable to research related to cell growth promotion .
|
-
- HY-179672
-
|
|
Biochemical Assay Reagents
|
Others
|
|
7.5M LiCl,RNase-free is a sterile, RNase- and DNase-free lithium chloride solution, commonly used for RNA precipitation. 7.5M LiCl,RNase-free can specifically precipitate RNA, effectively removing sugar, protein, and DNA contamination from RNA samples to obtain high-purity RNA samples. The pH of this solution is 5.5-6.0.
|
-
- HY-158220
-
|
HAMA (MW 400 kDa)
|
Biochemical Assay Reagents
|
Others
|
|
Hyaluronic acid Methacryloyl (HAMA) is methacrylated hyaluronic acid that is biocompatible. Hyaluronic acid Methacryloyl is also used as a 3D printing hydrogel ink, which has the characteristics of fast photosensitive response, fast gelation speed and stable hydrogel performance. Hyaluronic acid Methacryloyl can quickly induce gelation with lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP) under UV irradiation. The combination of Hyaluronic acid Methacryloyl and tissue-specific extracellular matrix (ECM) materials (such as pancreatic extracellular matrix (pECM)) will become an important source material for organoid culture .
|
-
- HY-W017092
-
|
|
Drug Intermediate
|
Others
|
|
1,2,3-Trimethoxybenzene is a model compound of lignin. 1,2,3-Trimethoxybenzene can potentially serve as a biomarker for certain foods due to its presence in tea. 1,2,3-Trimethoxybenzene can be used as a drug intermediate for synthesizing 2,6-dimethoxy-1,4-benzoquinone (HY-N1677) .
|
-
- HY-158220A
-
|
HAMA (MW 150 kDa)
|
Biochemical Assay Reagents
|
Others
|
|
Hyaluronic acid Methacryloyl (HAMA) MW 150 kDa is methacrylated hyaluronic acid that is biocompatible. Hyaluronic acid Methacryloyl is also used as a 3D printing hydrogel ink, which has the characteristics of fast photosensitive response, fast gelation speed and stable hydrogel performance. Hyaluronic acid Methacryloyl can quickly induce gelation with lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP) under UV irradiation. The combination of Hyaluronic acid Methacryloyl and tissue-specific extracellular matrix (ECM) materials (such as pancreatic extracellular matrix (pECM)) will become an important source material for organoid culture .
|
-
- HY-134557
-
|
|
GSK-3
|
Cancer
|
|
GS87 is a highly specific and potent GSK3 inhibitor with IC50s of 415nM and 521nM for GSK3α and GSK3β, respectively. GS87 induces differentiation of acute myeloid leukemia (AML) cell lines by effectively activating GSK3-dependent signaling components including MAPK signaling. GS87 modulates key GSK3 target proteins involved in cell proliferation and differentiation more effectively than Lithium and SB415285 (SB). GS87 has the potential for acting as a differentiation agent for non-promyelocytic AML research .
|
-
- HY-19938
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
MTL-005 is a boron-containing radiosensitizer used in Boron Neutron Capture Therapy (BNCT). MTL-005 enriches the boron-10 isotope in tumor tissues, causing nuclear fission under thermal neutron irradiation, releasing high linear energy transfer (LET) α particles and lithium ions, which selectively destroy tumor cells while minimizing damage to surrounding normal tissues. MTL-005 significantly controlls the tumor progression in the SCCVII squamous cell carcinoma mouse model and prolonged the survival of the mice. MTL-005 can be used to study solid tumors such as head and neck cancer.
|
-
- HY-W087830
-
|
L-BPA
|
Biochemical Assay Reagents
|
Cancer
|
|
L-p-Boronophenylalanine is a boron-containing substrate for L-type amino acid transporters (LAT1 and LAT2). L-p-Boronophenylalanine enters tumor cells by competing with natural amino acids for LAT, selectively accumulating boron in cancer cells. L-p-Boronophenylalanine can be used in boron neutron capture therapy (BNCT). When boron-10 captures thermal neutrons, a nuclear reaction occurs, producing high-energy alpha particles and lithium nuclei, which kill cancer cells at close range with little damage to surrounding tissues. L-p-Boronophenylalanine can be used in cancer research, especially glioblastoma and anaplastic astrocytoma .
|
-
- HY-160937
-
|
|
Ligands for Target Protein for PROTAC
PARP
|
Cancer
|
|
AZD-9574-acid (Compound 70D) is a PARP-1 ligand. AZD-9574-acid serves as a Ligand for Target Protein for PROTAC for the synthesis of PARP-1 PROTAC degraders. AZD-9574-acid is applicable to cancer research .
|
-
- HY-W007656
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cyclen is a macrocyclic tetraamine chelating agent. Cyclen is the aza analogue of crown ether, used as a precursor for MRI contrast agents, and is an intermediate for the preparation of effective macrocyclic chelates. Cyclen is employed as a structural regulator through interfacial polymerization of polyethleneimine (PEI) and trimesoyl chloride (TMC) to develop polyamide NF membrane with efficient Li +/Mg 2+ separation performance. Cyclen has specific cavity structure and exhibits selective coordination properties for Li + ions [1][2].
|
-
- HY-14608R
-
|
|
Reference Standards
Endogenous Metabolite
iGluR
Ferroptosis
Apoptosis
|
Neurological Disease
|
L-Glutamic acid (Standard) is the analytical standard of L-Glutamic acid. This product is intended for research and analytical applications. L-Glutamic acid is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid can be used in the study of neurological diseases .
IC50 & Target:DA .
In Vitro: L-Glutamic acid (120, 500, 750, 1000 mg/dL) can reduce the harmful effect of lithium on the embryonic development of Xenopus Xenopus .
L-Glutamic acid (2, 5, 10, 20 mM, 24-48 h) can induce neuroexcitotoxicity in neuroblastoma .
In Vivo: L-Glutamic acid (3 g/kg, subcutaneous injection) can promote excitotoxic degeneration of retinal ganglion cells in mice .
L-Glutamic acid (750 mg/kg, intraperitoneal injection) can reduce and inhibit oxidative stress induced by chlorpyrifos (CPF) in rats .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-Y0649
-
|
LiCl, Premium grade
|
Biochemical Assay Reagents
|
|
Lithium chloride, 99% (LiCl, Premium grade) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-44076
-
LAP
4 Publications Verification
Lithium phenyl-2,4,6-trimethylbenzoylphosphinate
|
Biochemical Assay Reagents
|
|
LAP (Lithium phenyl-2,4,6-trimethylbenzoylphosphinate) is a free radical initiator. The free radicals produced by LAP under bioprinting conditions are potentially cytotoxic and mutagenic. In addition, the concentration of LAP affects the mechanical strength of 3D printed scaffolds. Generally, the concentration range of LAP used for curing is 0.05%-1%. The elastic modulus produced at a concentration of 0.1% is the highest, with enhanced mechanical properties and excellent biocompatibility .
|
-
- HY-Y0649D
-
|
|
Biochemical Assay Reagents
|
|
Lithium chloride, for molecular biology, 99% can be used in the preparation of wash buffers for chromatin immunoprecipitation. Lithium chloride, for molecular biology, 99% is a kind of biological materials or organic compounds that are widely used in life science research .
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- HY-Y0292
-
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CarboLithium; Lithium carbonate
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Biochemical Assay Reagents
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Lithium carbonate (Carbolithium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-W099535
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Biochemical Assay Reagents
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Lithium dodecyl sulfate is an anionic hydrocarbon surfactant with both surface tension reduction and interfacial adsorption capabilities. Lithium dodecyl sulfate induces low surface viscosity; it forms micelles in aqueous solutions through entropy-driven (low temperature) and enthalpy-driven (high temperature) mechanisms. When acting synergistically with tetrabutylammonium bromide, Lithium dodecyl sulfate exhibits cloud point behavior due to micelle aggregation and phase separation. Lithium dodecyl sulfate can form an adsorption layer at the air-water interface with quantifiable surface excess and minimum area per molecule, and it has higher equilibrium surface tension and foamability compared to other dodecyl sulfate counterion variants. The foam stability of Lithium dodecyl sulfate above its critical micelle concentration is low, and its dynamic surface tension pattern changes dynamically with bubble frequency .
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- HY-130777A
-
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Adenylyl imidodiphosphate Lithium hydrate
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Biochemical Assay Reagents
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AMP-PNP (Adenylyl imidodiphosphate) lithium hydrate is a non-hydrolyzable ATP analog. AMP-PNP lithium hydrate binds to ATP binding sites competely but is not hydrolyzed by enzymes, providing stable experimental conditions for studying ATP-dependent processes. AMP-PNP lithium hydrate can also be used to study enzyme activity, kinase regulation, DNA/RNA metabolism, ion channel function, and protein complex assembly .
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-
- HY-134427
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|
Palmitoyl CoA Lithium
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Biochemical Assay Reagents
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Palmitoyl coenzyme A lithium is an acyl-CoA thioester that can be transported into the mitochondrial matrix via the carnitine shuttle system and is involved in β-oxidation. Palmitoyl coenzyme A lithium can also be used as a substrate for sphingosine biosynthesis .
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-
- HY-W087830
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L-BPA
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Biochemical Assay Reagents
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L-p-Boronophenylalanine is a boron-containing substrate for L-type amino acid transporters (LAT1 and LAT2). L-p-Boronophenylalanine enters tumor cells by competing with natural amino acids for LAT, selectively accumulating boron in cancer cells. L-p-Boronophenylalanine can be used in boron neutron capture therapy (BNCT). When boron-10 captures thermal neutrons, a nuclear reaction occurs, producing high-energy alpha particles and lithium nuclei, which kill cancer cells at close range with little damage to surrounding tissues. L-p-Boronophenylalanine can be used in cancer research, especially glioblastoma and anaplastic astrocytoma .
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- HY-W250174
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3,5-Diiodosalicylic acid Lithium salt
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Biochemical Assay Reagents
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Lithium 3,5-diiodosalicylate is a compound used in the study of bipolar disorder and other psychiatric disorders. It contains lithium and a salicylate. Lithium 3,5-diiodosalicylate works by affecting the levels of certain neurotransmitters in the brain, including dopamine and serotonin.
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-
- HY-134136A
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Biochemical Assay Reagents
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Octanoyl coenzyme A lithium is an enoyl-CoA hydratase binder. Octanoyl coenzyme A lithium binds to the active site of enoyl-CoA hydratase, occupies the binding pocket for the fatty acid tail of the enzyme's substrate, and induces a conformational shift in a flexible protein loop via its longer octanoyl chain, forming an open channel leading to the inter-trimer gap .
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-
- HY-134426
-
|
|
Biochemical Assay Reagents
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DL-β-Hydroxybutyryl coenzyme A lithium is an intermediate in the fermentation of butyric acid and the metabolism of lysine and tryptophan, and is produced from β-hydroxybutyric acid by short-chain-CoA synthase .
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-
- HY-113596A
-
|
Acetyl-CoA Lithium
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Biochemical Assay Reagents
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Acetyl-coenzyme A (Acetyl-CoA) lithium is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A lithium, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A lithium is also a key precursor of lipid synthesis .
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-
- HY-W007531
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Biochemical Assay Reagents
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2-Fluoro-5-iodopyridine is an electrolyte additive. 2-Fluoro-5-iodopyridine can not only effectively protect the anode by forming a stable SEI film, but also convert dead lithium into active lithium. 2-Fluoro-5-iodopyridine effectively improves the performance of lithium metal batteries .
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-
- HY-B1295
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|
Litarex tetrahydrate
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Biochemical Assay Reagents
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Lithium citrate (Litarex) tetrahydrate is a natural preservative and food tartness enhancer. Lithium citrate tetrahydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Lithium citrate tetrahydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Lithium citrate tetrahydrate is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .
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-
- HY-134421
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|
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Biochemical Assay Reagents
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2-Butenoyl coenzyme A lithium is an inactivator and a substrate of Plasmodium falciparum enoyl-β-hydroxyacyl-acyl carrier protein (ACP) reductase and other enoyl-CoA reductases, and it is also the lithium salt of trans-2-methyl-2-butenoyl coenzyme A. 2-Butenoyl coenzyme A lithium acts on short-chain and medium-chain coenzyme A dehydrogenases as well as glutaryl-CoA dehydrogenase, and shows no activity against wild-type isovaleryl-CoA dehydrogenase. 2-Butenoyl coenzyme A lithium functions as a metabolite in the L-isoleucine catabolic pathway, and can serve as a substrate in the activity assay of 3-ketothiolase. 2-Butenoyl coenzyme A lithium is applicable to research related to 3-ketothiolase deficiency .
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-
- HY-134424
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|
|
Biochemical Assay Reagents
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Propionyl coenzyme A lithium, a coenzyme A derivative of propionic acid, is an important metabolic intermediate formed by the thioester bond between coenzyme A and propionic acid. The breakdown and production of Propionyl coenzyme A lithim is important for the metabolism of organisms .
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-
- HY-W094471
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Biochemical Assay Reagents
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Lithium acetate dihydrate is a compound with a one-dimensional structure that has various applications in industries such as pharmaceuticals, ceramics, and research laboratories. Lithium acetate dihydrate is often used as a source of lithium ions in chemical reactions and as a precursor in the synthesis of other lithium compounds .
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-
- HY-141474
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|
Biochemical Assay Reagents
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Glutaryl coenzyme A lithium is an important endogenous metabolites. Glutaryl coenzyme A lithium can be used in HMG-CoA or Glutaryl-CoA related experiment.
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-
- HY-W250153
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|
Biochemical Assay Reagents
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Adenosine 3'-phosphate 5'-phosphosulfate lithium, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
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-
- HY-W010479
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|
Biochemical Assay Reagents
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Propane sultone is a multifunctional intermediate, which can be used for the synthesis of other active compounds. Propane sultone can also be used as an additive in lithium battery electrolytes .
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-
- HY-40145
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Biochemical Assay Reagents
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1-Boc-3-iodoazetidine acts as a bifunctional additive for lithium-oxygen (Li-O2) batteries and can be used to enhance the performance of Li-O2 batteries. 1-Boc-3-iodoazetidine is applied in the synthesis of C3-functionalized azetidines and C2-functionalized azetidines via a lithium/iodine exchange or β-elimination/lithiation reaction sequence .
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- HY-109591A
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Oleoyl-CoA Lithium
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Biochemical Assay Reagents
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Oleoyl coenzyme A (Oleoyl-CoA) lithium is a thioester of oleic acid and coenzyme A. Oleoyl coenzyme A lithium has a role as an Escherichia coli metabolite and a mouse metabolite .
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- HY-D0884
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(S)-2-Hydroxypropanoic acid Lithium
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Biochemical Assay Reagents
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L-Lactic acid lithium is a lithium salt of L-Lactic acid (HY-Y0479) with certain bioconductive properties. L-Lactic acid can be used as a precursor for the production of bioplastic polymer polylactic acid .
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- HY-126912A
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Biochemical Assay Reagents
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Lauroyl coenzyme A lithium salt is an intermediary in fatty acid synthesis or metabolism, formed by combining long-chain fatty acids (or lauric acid) with coenzyme A. Lauroyl coenzyme A lithium salt is involved in lipid biosynthesis and fatty acid transport, in which coenzyme A acts as a transport molecule to help move and target specific compounds.
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-
- HY-21170B
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Triflate Lithium; Trifluoromethylsulfonate Lithium; Trifluoromethanesulphonic acid Lithium
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Biochemical Assay Reagents
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Trifluoromethanesulfonate (Triflate;Trifluoromethylsulfonate) lithium is a stable lithium salt and dopant with four resonance states, which is commonly used as an electrolyte component in polymer light-emitting electrochemical cells and primary lithium batteries. Trifluoromethanesulfonate lithiumalso acts as a catalyst for the preparation of the herbicide Imazapyr. In MEH-PPV-based light-emitting electrochemical cells, Trifluoromethanesulfonate lithium promotes electrochemical p-type doping at the anode interface under applied bias, thereby facilitating the formation of p-i-n junctions, exciton generation, and light emission. Trifluoromethanesulfonate lithiumexhibits strong ion pairing in non-aqueous electrolytes, but its electrochemical stability window is narrower than that of lithium bistrifluoromethylsulfonyl imidee .
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- HY-W250163
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NAD+ lithium
Maximum Cited Publications
44 Publications Verification
β-DPN Lithium; β-NAD Lithium; β-Nicotinamide Adenine Dinucleotide Lithium
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Biochemical Assay Reagents
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NAD+ lithium (β-DPN lithium) is a lithium salt of nicotinamide adenine dinucleotide. NAD+ is a coenzyme in the REDOX reaction. NAD+ can directly or indirectly affect several key cellular functions, including metabolic pathways, DNA repair, chromatin remodeling, cell aging, and immune cell function .
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-
- HY-W010625
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Biochemical Assay Reagents
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Lithium 2-hydroxypropanoate is a lithium salt. Lithium 2-hydroxypropanoate has immunomodulatory activity (slightly enhancing PHA (HY-N7038)-induced lymphocyte proliferation). Lithium 2-hydroxypropanoate can be used in antioxidant activity assays. Lithium 2-hydroxypropanoate can be used in the research of mental diseases .
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-
- HY-158220
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HAMA (MW 400 kDa)
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Biochemical Assay Reagents
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Hyaluronic acid Methacryloyl (HAMA) is methacrylated hyaluronic acid that is biocompatible. Hyaluronic acid Methacryloyl is also used as a 3D printing hydrogel ink, which has the characteristics of fast photosensitive response, fast gelation speed and stable hydrogel performance. Hyaluronic acid Methacryloyl can quickly induce gelation with lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP) under UV irradiation. The combination of Hyaluronic acid Methacryloyl and tissue-specific extracellular matrix (ECM) materials (such as pancreatic extracellular matrix (pECM)) will become an important source material for organoid culture .
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- HY-158220A
-
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HAMA (MW 150 kDa)
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Biochemical Assay Reagents
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Hyaluronic acid Methacryloyl (HAMA) MW 150 kDa is methacrylated hyaluronic acid that is biocompatible. Hyaluronic acid Methacryloyl is also used as a 3D printing hydrogel ink, which has the characteristics of fast photosensitive response, fast gelation speed and stable hydrogel performance. Hyaluronic acid Methacryloyl can quickly induce gelation with lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP) under UV irradiation. The combination of Hyaluronic acid Methacryloyl and tissue-specific extracellular matrix (ECM) materials (such as pancreatic extracellular matrix (pECM)) will become an important source material for organoid culture .
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- HY-Y0643
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Pivaloyloxymethyl chloride
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Biochemical Assay Reagents
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Pivaloyloxymethyl chloride is an intermediate. Pivaloyloxymethyl chloride can be used in the synthesis of Compound 8b. Compound 8b can stimulate the production of interferon gamma .
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- HY-W017850
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Biochemical Assay Reagents
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1,5,2,4-Dioxadithiane 2,2,4,4-tetraoxide is a sulfur-containing electrolyte additive that can be used to prepare graphite/NMC111 lithium-ion cells .
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- HY-134428
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Biochemical Assay Reagents
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Arachidonoyl coenzyme A lithium is an unsaturated fatty acyl coenzyme A, formed by the condensation of the thiol group of coenzyme A with the carboxyl group of arachidonic acid .
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- HY-Y1810
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Biochemical Assay Reagents
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Diethylene glycol diethyl ether is an electrolyte solvent for a non-aqueous lithium-air cell. Diethylene glycol diethyl ether can facilitate the reversible reduction and oxidation processes at the porous carbon electrode without a catalyst .
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-
- HY-W010751
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|
2,3,4,6-Tetrakis-O-(phenylmethyl)-D-glucopyranose
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Biochemical Assay Reagents
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2,3,4,6-Tetra-O-benzyl-D-glucopyranose is a glucose derivative that serves as an important intermediate in the synthesis of complex glycoconjugates, oligosaccharides, and glycosylated drug molecules .
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- HY-W250153A
-
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Biochemical Assay Reagents
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Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
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- HY-139099A
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Gp3G Lithium
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Biochemical Assay Reagents
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Diguanosine 5′-triphosphate (Gp3G) lithium is a dinucleoside triphosphates. Diguanosine 5′-triphosphate lithium also is a virus-specific oligonucleotide. Diguanosine 5′-triphosphate lithium is needed for the synthesis of RNA during the transcription process .
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- HY-134422
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Isobutyryl CoA Lithium
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Biochemical Assay Reagents
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Isobutyryl coenzyme A (Isobutyryl CoA) lithium is A coenzyme A involved in the metabolic pathway of fatty acids. Isobutyryl coenzyme A lithium is made by combining isobutyric acid (short chain branched fatty acid) with coenzyme A.
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- HY-113013C
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β-Hydroxypyruvic acid Lithium; 3-Hydroxypyruvic acid Lithium
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Biochemical Assay Reagents
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Hydroxypyruvic acid (β-Hydroxypyruvic acid; 3-Hydroxypyruvic acid) lithium is a biochemical assay reagent.
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- HY-155743A
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2',3'-Dideoxyuridine-5'-triphosphate Lithium
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Biochemical Assay Reagents
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ddUTP (lithium), 100 mM in H2O is a nucleotide analog that can be incorporated into DNA, RNA, or other nucleic acids. ddUTP (lithium), 100 mM in H2O can be used to prepare DNA/RNA hybridization experiments, such as Southern blots and Northern blots.
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- HY-B1295R
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Litarex tetrahydrate (Standard)
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Biochemical Assay Reagents
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Lithium citrate (tetrahydrate) (Standard) is the analytical standard of Lithium citrate (tetrahydrate). This product is intended for research and analytical applications. Lithium citrate (Litarex) tetrahydrate is a natural preservative and food tartness enhancer. Lithium citrate tetrahydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Lithium citrate tetrahydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Lithium citrate tetrahydrate is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .
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- HY-134423
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Stearoyl-CoA Lithium
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Biochemical Assay Reagents
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Stearoyl coenzyme A (Stearoyl-CoA) lithium is an active compound that can be used as a substrate for the determination of stearoyl-Coenzyme desaturase in microsomes .
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- HY-134425
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Biochemical Assay Reagents
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β-Methylcrotonyl coenzyme A lithium is an intermediate in leucine metabolism and can be used as a substrate to study the specificity and kinetics of β-methylcrotonyl coenzyme A carboxylase (MCCase) .
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- HY-W010479R
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Biochemical Assay Reagents
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Propane sultone (Standard) is the analytical standard of Propane sultone (HY-W010479). This product is intended for research and analytical applications. Propane sultone is a multifunctional intermediate, which can be used for the synthesis of other active compounds. Propane sultone can also be used as an additive in lithium battery electrolytes .
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- HY-Y1005
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Biochemical Assay Reagents
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Triammonium phosphate trihydrate interacts with the magnesium ions to form a precipitate, which can be used for magnesium separation from lithium in salt-lake brines .
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- HY-179672
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Biochemical Assay Reagents
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7.5M LiCl,RNase-free is a sterile, RNase- and DNase-free lithium chloride solution, commonly used for RNA precipitation. 7.5M LiCl,RNase-free can specifically precipitate RNA, effectively removing sugar, protein, and DNA contamination from RNA samples to obtain high-purity RNA samples. The pH of this solution is 5.5-6.0.
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Target |
Research Area |
| Cat. No. |
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Target |
Research Area |
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- HY-119810A
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Ucb 44212 Lithium
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HIV
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Neurological Disease
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Seletracetam (Ucb 44212) lithium, as an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy .
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(5)
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
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- HY-113071A
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-
- HY-128730
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-
- HY-113128A
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- HY-W007656
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-
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- HY-112540A
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- HY-14608R
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Structural Classification
Microorganisms
Disease markers
Endocrine diseases
Amino acids
Nervous System Disorder
Endogenous metabolite
Cardiovascular System Disorder
Cancer
Source Classification
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Reference Standards
Endogenous Metabolite
iGluR
Ferroptosis
Apoptosis
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L-Glutamic acid (Standard) is the analytical standard of L-Glutamic acid. This product is intended for research and analytical applications. L-Glutamic acid is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid can be used in the study of neurological diseases .
IC50 & Target:DA .
In Vitro: L-Glutamic acid (120, 500, 750, 1000 mg/dL) can reduce the harmful effect of lithium on the embryonic development of Xenopus Xenopus .
L-Glutamic acid (2, 5, 10, 20 mM, 24-48 h) can induce neuroexcitotoxicity in neuroblastoma .
In Vivo: L-Glutamic acid (3 g/kg, subcutaneous injection) can promote excitotoxic degeneration of retinal ganglion cells in mice .
L-Glutamic acid (750 mg/kg, intraperitoneal injection) can reduce and inhibit oxidative stress induced by chlorpyrifos (CPF) in rats .
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- HY-134891
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(E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate Lithium
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Natural Products
Microorganisms
Source Classification
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Nuclear Factor of activated T Cells (NFAT)
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HMBPP lithium is an intermediate in isoprenoid biosynthesis that can be produced by bacteria and protozoa that use the non-mevalonate pathway for isoprenoid biosynthesis. HMBPP lithium is a ligand of the internal domain of BTN3A1 and is an activator for human Vγ9/Vδ2 T cells. HMBPP lithium exhibits phagostimulant property in mosquitos .
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- HY-B1295
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- HY-134421
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Human Gut Microbiota Metabolites
Microorganisms
Endogenous metabolite
Source Classification
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HMG-CoA Reductase (HMGCR)
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2-Butenoyl coenzyme A lithium is an inactivator and a substrate of Plasmodium falciparum enoyl-β-hydroxyacyl-acyl carrier protein (ACP) reductase and other enoyl-CoA reductases, and it is also the lithium salt of trans-2-methyl-2-butenoyl coenzyme A. 2-Butenoyl coenzyme A lithium acts on short-chain and medium-chain coenzyme A dehydrogenases as well as glutaryl-CoA dehydrogenase, and shows no activity against wild-type isovaleryl-CoA dehydrogenase. 2-Butenoyl coenzyme A lithium functions as a metabolite in the L-isoleucine catabolic pathway, and can serve as a substrate in the activity assay of 3-ketothiolase. 2-Butenoyl coenzyme A lithium is applicable to research related to 3-ketothiolase deficiency .
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- HY-126833A
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-
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- HY-113005A
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-
-
- HY-113304A
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-
-
- HY-N0216A
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-
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- HY-111525
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-
-
- HY-113013A
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-
-
- HY-113071AR
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MVA Lithium salt (Standard)
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Structural Classification
Ketones, Aldehydes, Acids
Endogenous metabolite
Source Classification
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Reference Standards
Endogenous Metabolite
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Mevalonic acid lithium salt (Standard) is the analytical standard of Mevalonic acid lithium salt. This product is intended for research and analytical applications. Mevalonic acid (MVA) lithium salt is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid lithium salt is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid lithium salt can be used in studies of myopathy and heart failure .
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- HY-135024A
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-
-
- HY-112540AR
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Structural Classification
Ketones, Aldehydes, Acids
Endogenous metabolite
Source Classification
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Endogenous Metabolite
Reference Standards
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Acetoacetic acid (lithium) (Standard) is the analytical standard of Acetoacetic acid (lithium). This product is intended for research and analytical applications. Acetoacetic acid lithium is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Acetoacetic acid lithium induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes. Acetoacetic acid lithium can be used to study metabolic diseases .
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- HY-B1295R
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Litarex tetrahydrate (Standard)
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Structural Classification
Microorganisms
Ketones, Aldehydes, Acids
Source Classification
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Apoptosis
Endogenous Metabolite
Bacterial
Reference Standards
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Lithium citrate (tetrahydrate) (Standard) is the analytical standard of Lithium citrate (tetrahydrate). This product is intended for research and analytical applications. Lithium citrate (Litarex) tetrahydrate is a natural preservative and food tartness enhancer. Lithium citrate tetrahydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Lithium citrate tetrahydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Lithium citrate tetrahydrate is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .
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-
- HY-134425
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-
-
- HY-113005AR
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* This product has been "discontinued".
Optimized version of product available:
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| Cat. No. |
Product Name |
Chemical Structure |
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- HY-114293S
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Acetyl coenzyme A- 13C2 lithium is the 13C-labeled Acetyl coenzyme A (HY-114293). Acetyl-coenzyme A (Acetyl-CoA) is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A is also a key precursor of lipid synthesis .
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-
- HY-134423S
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Stearoyl coenzyme A- 13C18 (lithium) is the 13C labeled Stearoyl coenzyme A lithium . Stearoyl coenzyme A (Stearoyl-CoA) lithium is an active compound that can be used as a substrate for the determination of stearoyl-Coenzyme desaturase in microsomes .
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-
- HY-179170S
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Malonyl CoA- 13C3 (Malonyl coenzyme A- 13C3) lithium is the 13C-labeled Malonyl CoA lithium (HY-136408). Malonyl CoA (Malonyl Coenzyme A) lithium is an inhibitor of carnitine palmitoyl transferase 1 (CPT1). High Malonyl CoA lithium concentrations suppress fatty acid oxidation, while low Malonyl CoA lithium concentrations are permissive for fat oxidation .
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-
- HY-144166S
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Silodosin glucuronide-d4 (lithium) is the deuterium labeled Silodosin glucuronide lithium .
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- HY-109591S
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Oleoyl coenzyme A- 13C18 (lithium) is the 13C labeled Oleoyl Coenzyme A lithium . Oleoyl coenzyme A (Oleoyl-CoA) is a thioester of oleic acid and coenzyme A. Oleoyl coenzyme A has a role as an Escherichia coli metabolite and a mouse metabolite .
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- HY-W744370
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Raloxifene 6-β-D-glucuronide-d4 lithium is the deuterium labeled Raloxifene 6-β-D-glucuronide lithium.
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- HY-143953S
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Estrone ?-D-Glucuronide-d4 (lithium) is the deuterium labeled Estrone ?-D-Glucuronide .
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- HY-135582S1
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Raloxifene 4'-glucuronide-d4 (lithium) is deuterium labeled Raloxifene 4'-glucuronide. Raloxifene 4'-glucuronide is a primary metabolite of Raloxifene. Raloxifene 4'-glucuronide formation is mediated mostly by UGT1A10 and UGT1A8. Raloxifene 4'-glucuronide binds to estrogen receptor with an IC50 of 370 μM. . Raloxifene is a selective estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression .
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- HY-135581S1
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Raloxifene 6-glucuronide-d4 (lithium) is deuterium labeled Raloxifene 6-glucuronide. Raloxifene 6-glucuronide is a primary metabolite of Raloxifene. Raloxifene 6-glucuronide is mediated mostly by UGT1A1 and UGT1A8. Raloxifene 6-glucuronide binds to estrogen receptor with an IC50 of 290 μM. Raloxifene is a selective and nonsteroidal estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression .
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Classification |
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- HY-W250153
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Nucleotide Analogs
Adenine Nucleotide
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Adenosine 3'-phosphate 5'-phosphosulfate lithium, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
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- HY-W250153A
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Nucleotide Analogs
Adenine Nucleotide
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Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
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- HY-172731
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Nucleoside Analogs
Adenosine
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8-Oxo-dATP lithium, as an oxidized purine nucleoside triphosphate, is hydrolyzed by MTH1 into monophosphates, thereby preventing errors caused by its misincorporation during DNA replication or transcription .
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