2. Search Result
Search Result
Results for "

MDP

" in MedChemExpress (MCE) Product Catalog:

22

Inhibitors & Agonists

5

Peptides

2

Recombinant Proteins

1

Isotope-Labeled Compounds

7

Antibodies

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-127090
    Muramyl dipeptide
    Maximum Cited Publications
    10 Publications Verification

    MDP

    		 p38 MAPK NOD-like Receptor (NLR) Inflammation/Immunology Cancer
    Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide is an inducer of bone formation through induction of Runx2. Muramyl dipeptide directly enhances osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways. Muramyl dipeptide is a NLRP1 agonist .
    Muramyl dipeptide
  • HY-13682
    Mifamurtide
    5 Publications Verification

    MTP-PE; L-MTP-PE; CGP 19835

    		 NOD-like Receptor (NLR) Inflammation/Immunology Cancer
    Mifamurtide (MTP-PE), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide has potential for use in rare disease and osteosarcoma research .
    Mifamurtide
  • HY-148690
    L18-MDP

    		Bacterial Fungal Infection
    L18-MDP is a derivative of muramyl dipeptide, an antibacterial agent. L18-MDP has antibacterial activity and has potential applications in bacterial and fungal infections .
    L18-MDP
  • HY-136555
    GSK717
    5+ Cited Publications

    		 NOD-like Receptor (NLR) Inflammation/Immunology
    GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells .
    GSK717
  • HY-147506
    NOD2 antagonist 1

    		NOD-like Receptor (NLR) Inflammation/Immunology
    NOD2 antagonist 1 (compound 32) is a potent and selective NOD2 antagonist with an IC50 of 5.23 μM. NOD2 antagonist 1 inhibits Muramyl dipeptide (MDP)-induced IL-8 secretion in THP-1 cells and inhibits MDP-induced IL-6, IL-10, TNF-α release in PBMCs .
    NOD2 antagonist 1
  • HY-155863
    AJ2-71

    		Sodium Channel Inflammation/Immunology
    AJ2-71 is a SLCl5A4 inhibitor. AJ2-71 inhibits IFN-α production. AJ2-71 blocks SLC15A4-mediated MDP transport. AJ2-71 can be used for research of inflammation .
    AJ2-71
  • HY-155782
    Zharp2-1

    		RIP kinase Inflammation/Immunology
    Zharp2-1 is an oral effective RIPK2 inhibitor, highly associated with inflammatory bowel disease (IBD). Zharp2-1 blocker muramyl dipeptide (MDP) induces growth of mononuclear cells and induces inflammatory cell factor infection. Zharp2-1 attenuates MDP-induced small inguinal peritonitis, or ameliorates by DNBS-induced large inguinal conjunctivitis .
    Zharp2-1
  • HY-P3328A
    MDP1 acetate

    		Bacterial Infection
    MDP1 acetate, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 acetate has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa .
    MDP1 acetate
  • HY-13682B
    Mifamurtide sodium
    5 Publications Verification

    MTP-PE sodium; L-MTP-PE sodium; CGP 19835 sodium

    		 NOD-like Receptor (NLR) Inflammation/Immunology Cancer
    Mifamurtide sodium (MTP-PE sodium), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide sodium is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide sodium has potential for use in rare disease and osteosarcoma research .
    Mifamurtide sodium
  • HY-13682C
    Mifamurtide TFA
    5 Publications Verification

    MTP-PE TFA; L-MTP-PE TFA; CGP 19835 TFA

    		 NOD-like Receptor (NLR) Inflammation/Immunology Cancer
    Mifamurtide TFA (MTP-PE TFA), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide TFA is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide TFA has potential for use in rare disease and osteosarcoma research .
    Mifamurtide TFA
  • HY-170331
    IFNα-IN-1

    		IFNAR Inflammation/Immunology
    IFNα-IN-1 (AJ2-18) is a IFNα inhibitor that inhibits IFN-α production. IFNα-IN-1 can be used for research of inflammation .
    IFNα-IN-1
  • HY-157325
    RIPK2-IN-5

    		RIP kinase Inflammation/Immunology
    RIPK2-IN-5 (compound 14) is a high affinity and excellent selectivity RIPK2 inhibitor with an IC50 value of 5.1nM. RIPK2-IN-5 has cellular anti-inflammatory effect and can reduce the secretion of MDP-induced TNF-α with a dose-dependent manner. RIPK2-IN-5 shows moderate stability in human liver microsome. RIPK2-IN-5 can be used for the research of immune diseases .
    RIPK2-IN-5
  • HY-110104
    8MDP

    		Transmembrane Glycoprotein Others
    8MDP is a potent equilibrative nucleoside transporter 1 (ENT1) inhibitor with an IC50 of 0.43 nM. 8MDP inhibits hENT1 and hENT2 uptake of [H 3] uridine by K562 cells and K15NTD cells .
    8MDP
  • HY-16384
    L-156602

    Antibiotic L 156602; PD 124966

    		 Complement System Inflammation/Immunology
    L-156602 is a C5a receptor antagonist. L-156602 inhibits inflammation, and the migration of monocytes and neutrophils to the infiltrating site in mouse inflammatory models. L-156602 suppresses the efferent phase of delayed-type hypersensitivity (DTH) .
    L-156602
  • HY-P4236
    Gly-d-Phe

    		Carboxypeptidase Others
    Gly-d-Phe is an affinity ligand for Thermolysin (HY-P1748) . Gly-d-Phe can be used as the substrate of membrane dipeptidase (MDP) .
    Gly-d-Phe
  • HY-P3328
    MDP1

    		Bacterial Infection
    MDP1, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa .
    MDP1
  • HY-RS24515
    Mdp1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Mdp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mdp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Mdp1 Rat Pre-designed siRNA Set A
    Mdp1 Rat Pre-designed siRNA Set A
  • HY-RS08269
    MDP1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    MDP1 Human Pre-designed siRNA Set A contains three designed siRNAs for MDP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    MDP1 Human Pre-designed siRNA Set A
    MDP1 Human Pre-designed siRNA Set A
  • HY-RS03947
    DPEP1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    DPEP1 Human Pre-designed siRNA Set A contains three designed siRNAs for DPEP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    DPEP1 Human Pre-designed siRNA Set A
    DPEP1 Human Pre-designed siRNA Set A
  • HY-122529
    Almurtide

    		Bacterial Infection
    Almurtide (nor-MDP), a muramyl dipeptide derivative with anti-inflammatory and anti-tumor activity. Almurtide also shows protective effects against intraperitoneal Pseudomonas aeruginosa infection or intravenously Candida albicans infection in mice. Almurtide also inhibits the carcinogenic Friend leukemia virus .
    Almurtide
  • HY-RS18041
    Mdp1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Mdp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mdp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Mdp1 Mouse Pre-designed siRNA Set A
    Mdp1 Mouse Pre-designed siRNA Set A
  • HY-127090S
    Muramyl dipeptide-d3

    MDP-d3

    		 Isotope-Labeled Compounds p38 MAPK NOD-like Receptor (NLR) Others
    Muramyl dipeptide-d3 (MDP-d3) is the deuterium labeled Muramyl dipeptide. Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide is an inducer of bone formation through induction of Runx2. Muramyl dipeptide directly enhances osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways. Muramyl dipeptide is a NLRP1 agonist .
    Muramyl dipeptide-d3

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: