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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
142 Results for "
P388/ADM
" in MedChemExpress (MCE) Product Catalog:
Products (142)
142 Results for "P388/ADM" in MCE Product Catalog:
4
Category:
3
3 Cited Publications
Art. -Nr.: HY-N3308
CAS. Nr.: 32383-76-9
Category:
Monophenols Phenols Leguminosae Extract Plants Disease Research Fields Cancer Medicago sativa L.
Target:
3
Category:
Terpenoids Ulex europaeus L. Diterpenoids Plants Disease Research Fields Oxytropis falcata Bunge Cancer Labiatae Extract
Target:
2
2 Cited Publications
Synonyms: 5,10-Methylenetetrafolate; ANX-510 free acid
Target:
1
N-Acetyltyramine is a quorum-sensing inhibitor (QSI) compound produced by V. alginolyticus M3-10. N-Acetyltyramine is capable of inhibiting the QS of C. violaceum ATCC 12472. N-acetyltyramine reverses resistance in Doxorubicin-resistant leukemia P388 cells .
1
1 Cited Publications
Art. -Nr.: HY-P99177
CAS. Nr.: 2305638-98-4
Target:
Forschungsgebiete:
1
Art. -Nr.: HY-18351
CAS. Nr.: 915303-09-2
Synonyms: LMP-400; NSC-724998
Target:
Indotecan (LMP-400), an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor, with IC50s of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. Indotecan prevents the relaxation of supercoiled DNA and can be used for the research of visceral leishmaniasis .
Art. -Nr.: HY-18351A
CAS. Nr.: 1228035-68-4
Synonyms: LMP-400 hydrochloride; NSC-724998 hydrochloride
Target:
Indotecan hydrochloride, an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor, with IC50s of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. Indotecan hydrochloride prevents the relaxation of supercoiled DNA and can be used for the research of visceral leishmaniasis .
Art. -Nr.: HY-P3116
CAS. Nr.: 173046-02-1
Art. -Nr.: HY-108603
CAS. Nr.: 87745-28-6
Synonyms: (+)-Bryostatin 2
Bryostatin 2 ((+)-Bryostatin 2) is a 20-membered ring lactone that can be found in Bryozoan Eugufa neritina L. Bryostatin 2 has the potential for the research of P-388 lymphocytic
leukemia .
Art. -Nr.: HY-N6955
CAS. Nr.: 757202-08-7
Category:
Melilotus albus Desr. Terpenoids Sesquiterpenes Plants Compositae Extract Disease Research Fields Cancer
Target:
Art. -Nr.: HY-124277
CAS. Nr.: 1644134-60-0
Target:
Forschungsgebiete:
ADM 12 is a highly selective transient receptor potential ankyrin 1 (TRPA1) channel antagonist. ADM 12 blocks nitroglycerin (NTG)-induced trigeminal hyperalgesia in animal models, reducing expression of pain-related genes (c-Fos, TRPA1) and neuropeptides (CGRP, SP). ADM_12 is promising for research of migraine and neuropathic pain .
Art. -Nr.: HY-N10208
CAS. Nr.: 1216840-17-3
Category:
Natural Products Microorganisms Marine natural products Disease Research Fields Marine microorganism Cancer
Target:
Art. -Nr.: HY-12458
CAS. Nr.: 118292-36-7
Target:
Pyrindamycin A is an antibiotic that inhibits DNA synthesis. Pyrindamycin A shows antitumor activities against murine leukemia, exhibits stronger cytotoxic activities towards murine and human tumor cell lines and especially towards doxorubicin-resistant cells, inhibits P388 and P388/ADR cells with the same IC50 of 3.9 μg/ml .
Art. -Nr.: HY-N1631
CAS. Nr.: 53600-24-1
Synonyms: 1-Hydroxyrutaecarpine
Target:
Forschungsgebiete:
1-Hydroxyrutaecarpine (compound 1a) is a hydroxy-derivative of rutaecarpine. 1-Hydroxyrutaecarpine shows cytotoxicities with ED50s of 3.72, 7.44 µg/mL for P-388 and HT-29 cells, respectively. 1-Hydroxyrutaecarpine shows antiplatelet activity .
Art. -Nr.: HY-125037
CAS. Nr.: 1190948-58-3
Category:
Target:
Target:
1-Hydroxyguanidine sulfate is an antitumor agent that inhibits mast cell P815, leukaemia P388, leukaemia L1210 and carcinosarcoma Walker 256 cells growth. 1-Hydroxyguanidine sulfate also has antiviral activity .
Art. -Nr.: HY-N1655
CAS. Nr.: 873999-88-3
Category:
Flavonoids Phenols Polyphenols Selaginella delicatula (Desv.) Alston Plants Disease Research Fields Biflavones Cancer Selaginellaceae Extract
Target:
Synonyms: 2-Aminoadamantane-2-carboxylic acid
Target:
Forschungsgebiete:
Adamantanine (2-Aminoadamantane-2-carboxylic acid) inhibits the transport of methionine (Ki is 0.76 mM) and leucine into Ehrlich ascites carcinoma cells. Adamantanine inhibits proliferation of P388 lymphocytic leukemia cells with an IC50 of >1 mM. Adamantanine inhibits the leucine aminopeptidase with an I/S0.5 of 10.5 .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
