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PES

" in MedChemExpress (MCE) Product Catalog:

237

Inhibitors & Agonists

25

Fluorescent Dye

53

Biochemical Assay Reagents

4

Peptides

1

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3

Inhibitory Antibodies

34

Natural
Products

1

Recombinant Proteins

25

Isotope-Labeled Compounds

3

Antibodies

83

Oligonucleotides

1

GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N5034
    Phosphorylethanolamine
    4 Publications Verification

    Monoaminoethyl phosphate; NSC 254167; O-Phosphoethanolamine

    Endogenous Metabolite Neurological Disease Metabolic Disease Cancer
    Phosphorylethanolamine (Monoaminoethyl phosphate) is a membrane phospholipid and an important precursor of Phosphatidylcholine (HY-B2233B). It is found in most animal tissues and various human extracranial tumors, playing a critical role in membrane integrity, cell division, mitochondrial respiratory function, and more. Studies have shown that changes in the abundance of Phosphorylethanolamine are associated with Alzheimer's disease and Parkinson's disease. Lowering the ratio of Phosphorylethanolamine to Phosphatidylcholine in the liver can improve insulin signaling. Phosphorylethanolamine holds promise for research in the fields of cancer, neurodegenerative disorders, and metabolic diseases .
    Phosphorylethanolamine
  • HY-B0304A
    Dapoxetine hydrochloride
    1 Publications Verification

    LY-210448 hydrochloride

    Serotonin Transporter Neurological Disease
    Dapoxetine (LY-210448) hydrochloride is an orally active and selective serotonin reuptake inhibitor (SSRI). Dapoxetine hydrochloride can be used for the research of premature ejaculation (PE) .
    Dapoxetine hydrochloride
  • HY-W583868

    1,2-POPE; 16:0-18:1 PE

    Liposome Others
    1-Palmitoyl-2-oleoyl-sn-glycero-3-PE (1,2-POPE; 16:0-18:1 PE) is a phosphatidylethanolamine (PE) lipid. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can induce lipid bilayer to form a hexagonal phase (HII) structure in an acidic environment and promote membrane fusion. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can enhance the endosomal escape ability of lipid nanoparticles (LNPs) and improve the cellular delivery efficiency of nucleic acid drugs such as mRNA. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can be used for LNP carrier targeting of gene therapy and mRNA vaccines .
    1-Palmitoyl-2-oleoyl-sn-glycero-3-PE
  • HY-D1683
    NBD-PE
    2 Publications Verification

    Fluorescent Dye Others
    NBD-PE is an effective lipid fluorescent probe (Excitation/Emission: 465/535 nm; Color: Green). NBD-PE offers a wide array of applications in membrane and cell biology .
    NBD-PE
  • HY-162543

    18:1 Lissamine rhodamine PE

    Fluorescent Dye Others
    18:1 Liss Rhod (18:1 Lissamine rhodamine) PE is a fluorescent phospholipid and fluorescent probe.18:1 Liss Rhod PE admixes into phospholipid inks for large-scale monitoring of dip-pen nanolithography-generated lithographic structures via fluorescence microscopy.18:1 Liss Rhod PE undergoes phase separation or self-quenching under certain conditions in thin lipid membrane stacks .
    18:1 Liss Rhod PE
  • HY-NP137

    Biochemical Assay Reagents Inflammation/Immunology
    NP-PE (Phycoerythrin) is a complex formed by 4-Hydroxy-3-nitrophenylacetyl (NP, a hapten) with Phycoerythrin (PE, a carrier protein). NP-PE (Phycoerythrin) can induce the formation of specific immune complexes and mediate the targeted encounter and activation of B cells with antigens. NP-PE (Phycoerythrin) can be used to study the mechanisms by which B cells capture and transport immune complexes in lymph nodes .
    NP-PE (Phycoerythrin)
  • HY-144013
    18:0 mPEG2000 PE ammonium
    1 Publications Verification

    DSPE-mPEG2000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium

    Liposome Others
    18:0 mPEG2000 PE (DSPE-mPEG2000) ammonium is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:0 mPEG2000 PE ammonium can be used for drug delivery .
    18:0 mPEG2000 PE ammonium
  • HY-P3581

    Potassium Channel Neurological Disease
    PE 22-28 is a TREK-1 inhibitor with IC50 value of 0.12 nM. PE 22-28 also is a 7 amino-acid peptide that is used as a core sequence for preparing analogs by chemical modifications and also by substitution of amino-acids. PE 22-28 can be used for the research of depression .
    PE 22-28
  • HY-157688

    PE(18:1p/0:0)

    Endogenous Metabolite Liposome Metabolic Disease
    C18(Plasm) LPE (PE(18:1p/0:0)) is a bioactive lipid with the activity of regulating cell signaling and promoting cell growth.
    C18(Plasm) LPE
  • HY-112747

    LPI; PE (soy)

    Phospholipase Infection
    Soy PE (LPI) is the most abundant phospholipid in prokaryotes and the second most abundant found in the membrane of mammalian, plant, and yeast cells, comprising approximately 25% of total mammalian phospholipids. In the brain, phosphatidylethanolamine comprises almost half of the total phospholipids. It is synthesized mainly through the cytidine diphosphate-ethanolamine and phosphatidylserine decarboxylation pathways, which occur in the endoplasmic reticulum (ER) and mitochondrial membranes, respectively. It is a precursor in the synthesis of phosphatidylcholine and arachidonoyl ethanolamide and is a source of ethanolamine used in various cellular functions. In E.coli, phosphatidylethanolamine deficiency prevents proper assembly of lactose permease, suggesting a role as a lipid chaperone. It is a cofactor in the propagation of prions in vitro and can convert recombinant mammalian proteins into infectious molecules even in the absence of RNA. This product contains phosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 and sn-2 positions .
    Soy PE
  • HY-141617

    Liposome Metabolic Disease
    1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring lysophospholipid. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE also acts as an immune response regulator and toxicity alleviator produced by Microcystis aeruginosa under Cu 2+ stress .
    1-Palmitoyl-2-hydroxy-sn-glycero-3-PE
  • HY-120991

    1-Palmitoyl-2-linoleoyl PE; (1-Palmitoyl, 2-linoleoyl)-phosphatidylethanolamine; (1-Palmitoyl, 2-linoleoyl)-phosphoethanolamine

    Liposome Others
    1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE (1-Palmitoyl-2-linoleoyl PE) is a lipid, which promotes nucleic acid such as sRNA to absorb and enter the target cell .
    1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE
  • HY-115701

    1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-phosphoethanolamine; 15(S)-HpETE-SAPE; 15(S)-hydroperoxyeicostetraenoic acid-SAPE

    Ferroptosis Inflammation/Immunology
    1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-Pe (SAPE) by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.
    1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe
  • HY-N15936

    Toll-like Receptor (TLR) Interleukin Related Inflammation/Immunology
    a15:0-i15:0 PE is a diacyl phosphatidylethanolamine with two branched chains. a15:0-i15:0 PE is a non-canonical TLR2-TLR1 heterodimer agonist and has immunogenic activity. a15:0-i15:0 PE activates T cells and DC signaling and shows anti-inflammatory activity. a15:0-i15:0 PE induces TNFα and IL-6 production. a15:0-i15:0 PE is a the major component (approximately 50%) of A. muciniphila’s lipid membrane .
    a15:0-i15:0 PE
  • HY-144010

    DOPE-PEG2000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium

    Liposome Others
    18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) can be used for drug delivery .
    18:1 PEG2000 PE ammonium
  • HY-157697

    18:0p/20:4-PE; C18(Plasm)-20:4-PE; PE(P-18:0/20:4)

    Endogenous Metabolite Metabolic Disease
    1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PE (18:0p/20:4-PE; C18(Plasm)-20:4-PE) is a plasmalogen that contains 1(Z)-octadecenoic acid and arachidonic acid (HY-109590) at the sn-1 and sn-2 positions, respectively.
    1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PE
  • HY-NP041

    BSA-PE

    Biochemical Assay Reagents Others
    Bovine Serum Albumin-PE (BSA-PE) is a biochemical reagent conjugated to fluorescein PE (Ex=565 nm; Em=578 nm). Bovine Serum Albumin-PE can be used to label or detect specific antigens, molecules or cellular structures .
    Bovine Serum Albumin-PE
  • HY-157629

    PAPE; 1-Palmitoyl-2-arachidonoyl PE

    Reactive Oxygen Species (ROS) Others
    1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PE (PAPE), a compound isolated from egg yolk with antioxidant activity related to the unsaturated fatty acid content, was extracted, purified, and analyzed by various techniques.
    1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PE
  • HY-143203

    1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine

    Liposome Cancer
    18:0-18:2 PE is an important component of phosphatidylethanolamine (PE), involved in phospholipid metabolism and associated with diseases such as ovarian cancer. 18:0-18:2 PE in the hot processing process, its unsaturated fatty acids will degrade to form a variety of odor active compounds. 18:0-18:2 PE is mainly used in the field of food science to improve the flavor of aquatic products, as well as medical research on diseases related to phospholipid metabolism .
    18:0-18:2 PE
  • HY-W322225

    DLPE; 1,2-Dilauroyl-sn-glycero-3-PE

    Liposome Others
    1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE) is a derivative of phosphatidylethanolamine with lauric acid (12:0) acyl chains. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine can be used to synthesize liposomes .
    1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine
  • HY-125273

    Fluorescent Dye Phosphoglycerate Dehydrogenase (PHGDH) Others
    DNS-pE is a 3-phosphoglycerate dehydrogenase (PHGDH) inhibitor with a Ki of 7.4 μM. DNS-pE selectively and irreversibly covalently modifies endogenous PHGDH in live mammalian cells, its vinyl sulfone moiety acts as a fluorescence quencher that becomes highly fluorescent upon covalent modification of PHGDH. DNS-pE can be used as a fluorescent dye for live-cell imaging .
    DNS-pE
  • HY-D1556

    1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) ammonium

    Fluorescent Dye Cancer
    18:1 PE CF (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) (ammonium)) is a pH-sensitive fluorescent indicator. 18:1 PE CF exhibits changes in fluorescence intensity in response to pH variations and reflects the electrostatic states of cationic liposomes and lipoplexes. 18:1 PE CF supports real-time visualization of pH distribution and membrane deformation in giant unilamellar vesicles and is suitable for steady-state fluorescence testing in large unilamellar vesicle membranes. 18:1 PE CF is capable of monitoring the surface electrical potential of cationic liposomes and lipoplexes and can effectively label lipid bilayers and nanomicelles. 18:1 PE CF can be used for the research of the investigation of lung cancer (Ex = 495 nm; Em = 520 nm) .
    18:1 PE CF
  • HY-B0304

    (S)-(+)-Dapoxetine; LY-210448

    Serotonin Transporter Neurological Disease
    Dapoxetine (LY-210448) is an orally active and selective serotonin reuptake inhibitor (SSRI). Dapoxetine can be used for the research of premature ejaculation (PE) .
    Dapoxetine
  • HY-146882S
    16:0-18:1 PE-d31
    1 Publications Verification

    Isotope-Labeled Compounds Others
    16:0-18:1 PE-d31 is deuterium labeled 16:0-18:1 PE.
    16:0-18:1 PE-d31
  • HY-165116

    18:0p/22:6-PE; C18(Plasm)-22:6-PE; PE(P-18:0/22:6)

    Endogenous Metabolite Others
    1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE (18:0p/22:6-PE) is a lipid identified in rat brain tissue by mass spectrometry imaging with specific structural and distribution characteristics, and isomers of different fatty acid chains can be identified by improved methods.
    1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE
  • HY-D2762

    Fluorescent Dye Cancer
    18:1 PE AF 594 triammonium is a fluorescently labeled phospholipid probe. 18:1 PE AF 594 triammonium can be used as a fluorescent tracer for lipid nanoparticles (LNPs). 18:1 PE AF 594 triammonium is promising for research of drug delivery systems .
    18:1 PE AF 594 triammonium
  • HY-P5809

    μ-TrTx-Pe1b

    Sodium Channel Neurological Disease
    Pe1b (μ-TrTx-Pe1b) is a selective Nav1.7 inhibitor with an IC50 of 167 nM .
    Pe1b
  • HY-174377

    Androgen Receptor p38 MAPK Caspase Cytochrome P450 Calcium Channel Reactive Oxygen Species (ROS) Apoptosis Mitochondrial Metabolism GLUT Cancer

    PeS-9 is an Androgen Receptor (AR) degrader that induces androgen receptor degradation PeS-9 induces mitochondrial and ER stress by promoting cytotoxic ROS production, leading to the release of mitochondrial cytochrome C and AIF. PeS-9 subsequently activates caspases-9 and -3, causing DNA fragmentation and apoptotic cell death. PeS-9 has anticancer activity against prostate cancer and exerts in vivo antitumor and antimetastatic activity with minor side effects. PeS-9 can be used for the study of targeting monotherapy against GLUT-1-overexpressing tumors .

    PeS-9
  • HY-118431

    Biochemical Assay Reagents Others
    DMABA NHS ester can chemically react with the primary amine groups of the major phospholipid component of the cell membrane, Phosphatidylethanolamine (PE). Through precursor ion scanning, all PE subclasses labeled with DMABA can be detected. DMABA NHS ester can be used in combination with isotope-labeled compounds such as DMABA-d6 NHS ester, DMABA-d10 NHS ester, and DMABA-d4 NHS ester to observe changes in the distribution of PE lipids and the formation of novel PE lipid products .
    DMABA NHS ester
  • HY-167894

    Serotonin Transporter Neurological Disease
    DA-8031 is a selective and orally active serotonin reuptake inhibitor. DA-8031 can be used for the research of premature ejaculation (PE) .
    DA-8031
  • HY-RS10336

    Small Interfering RNA (siRNA) Others

    PES1 Human Pre-designed siRNA Set A contains three designed siRNAs for PES1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PES1 Human Pre-designed siRNA Set A
    PES1 Human Pre-designed siRNA Set A
  • HY-173171

    Biochemical Assay Reagents Others
    Lyso-PE-PEG5000 sodium is a biomaterial coupled with Lyso-PE and PEG5000, which can be used for drug delivery.
    Lyso-PE-PEG5000 sodium
  • HY-N16102

    LGPE 13:0

    Drug Intermediate Liposome Cancer
    13:0 Lyso PE is an intermediate. 13:0 Lyso PE can be used to synthesize tumor-triggered, targeted ammonium bicarbonate liposomes.
    13:0 Lyso PE
  • HY-157625

    1-Palmitoyl-2-Docosahexaenoyl-sn-glycero-3-PE; PE(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))

    Biochemical Assay Reagents Metabolic Disease
    1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine (1-Palmitoyl-2-Docosahexaenoyl-sn-glycero-3-PE; PE(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))) is an ester product.
    1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine
  • HY-174286

    Liposome Others
    C16-18:1 PE is a lipid. C16-18:1 PE has the activity of promoting membrane fusion and enhancing endosomal escape, which can significantly improve the delivery efficiency of mRNA. C16-18:1 PE is used in the synthesis of lipid nanoparticles (LNP) .
    C16-18:1 PE
  • HY-146837S

    Isotope-Labeled Compounds Others
    C18(plasm)-18:1 PE-d9 is deuterium labeled C18(plasm)-18:1 PE.
    C18(plasm)-18:1 PE-d9
  • HY-160271

    Fluorescent Dye Others
    DSPE-CH2-PEG2000-Fluor 488 is a PEG lipid conjugate with a DSPE group and a Fluor 488 dye. DSPE is a phosphoethanolamine (PE) lipid that can be used in the synthesis of liposomes. And Fluor 488 is a fluorescent dye .
    DSPE-CH2-PEG2000-Fluor 488
  • HY-160274

    Fluorescent Dye Others
    DSPE-PEG2000-Fluor 555 is a PEG lipid conjugate with a DSPE group and a Fluor 555 dye. DSPE is a phosphoethanolamine (PE) lipid that can be used in the synthesis of liposomes. And Fluor 555 is a fluorescent dye .
    DSPE-PEG2000-Fluor 555
  • HY-B0304R

    (S)-(+)-Dapoxetine (Standard); LY-210448 (Standard)

    Reference Standards Serotonin Transporter Neurological Disease
    Dapoxetine (Standard) is the analytical standard of Dapoxetine. This product is intended for research and analytical applications. Dapoxetine (LY-210448) is an orally active and selective serotonin reuptake inhibitor (SSRI). Dapoxetine can be used for the research of premature ejaculation (PE) .
    Dapoxetine (Standard)
  • HY-B0304AR

    LY-210448 hydrochloride (Standard)

    Reference Standards Serotonin Transporter Neurological Disease
    Dapoxetine (hydrochloride) (Standard) is the analytical standard of Dapoxetine (hydrochloride). This product is intended for research and analytical applications. Dapoxetine (LY-210448) hydrochloride is an orally active and selective serotonin reuptake inhibitor (SSRI). Dapoxetine hydrochloride can be used for the research of premature ejaculation (PE) .
    Dapoxetine hydrochloride (Standard)
  • HY-D1501

    Fluorescent Dye Others
    Fura PE-3 potassium is a Ca 2+sensitive fluorophore. Fura PE-3 potassium loads in IPA (intrapulmonary arteries) and MA (mesenteric resistance arteries) for the research of vasoconstriction .
    Fura PE-3 potassium
  • HY-176006

    Diheptanoyl thio-PE

    Lipase Others
    1,2-Bis(heptanoylthio)-sn-glycero-3-PE (Diheptanoyl thio-PE) is a sulfur-containing phosphoethanolamine.
    1,2-Bis(heptanoylthio)-sn-glycero-3-PE
  • HY-141617S

    Isotope-Labeled Compounds Others
    1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PE is the deuterium labeled 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE .
    1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PE
  • HY-W800784

    Liposome Cancer
    23:2 Diyne PE [DC(8,9)PE] is a phospholipase-mediated hydrolyzed phosphocoline with palmitic acid (16:0) and Pentacosa-10,12-diynoic acid for tails.
    23:2 Diyne PE [DC(8,9)PE]
  • HY-158947S

    Isotope-Labeled Compounds Others
    1-1(Z)-Hexadecenyl-2-Palmitoyl-d9-sn-glycero-3-PE is deuterium labeled 1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PE .
    1-1(Z)-Hexadecenyl-2-Palmitoyl-d9-sn-glycero-3-PE
  • HY-D1683A

    Fluorescent Dye Others
    NBD-X PE is a derivative of NBD-PE, where the NBD part is replaced by NBD-X acid.
    NBD-X PE
  • HY-146843S

    Isotope-Labeled Compounds Others
    17:0 Lyso PE-d5 is deuterium labeled 17:0 Lyso PE.
    17:0 Lyso PE-d5
  • HY-146844S

    Isotope-Labeled Compounds Others
    19:0 Lyso PE-d5 is deuterium labeled 19:0 Lyso PE.
    19:0 Lyso PE-d5
  • HY-146847S

    Isotope-Labeled Compounds Others
    17:0-18:1 PE-d5 is deuterium labeled 17:0-18:1 PE.
    17:0-18:1 PE-d5
  • HY-146846S

    Isotope-Labeled Compounds Others
    17:0-20:3 PE-d5 is deuterium labeled 17:0-20:3 PE.
    17:0-20:3 PE-d5

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