PI3K/Akt signaling activation

Natural Products Microorganisms Disease Research Fields Inflammation/Immunology

Ser/Thr Protease Cathepsin Autophagy SARS-CoV Atg8/LC3 NO Synthase COX p62 Arginase PTEN NF-κB PI3K Akt p38 MAPK ERK Reactive Oxygen Species (ROS)

Cardiovascular Disease Alkaloids other families Phenols Polyphenols Plants Disease Research Fields Alkaloid Dimers

Reactive Oxygen Species (ROS) Autophagy Apoptosis VEGFR JAK Amyloid-β p38 MAPK HIF/HIF Prolyl-Hydroxylase STAT PI3K JNK Akt

Alkaloids other families Phenols Polyphenols Plants Disease Research Fields Isoquinoline Alkaloids Inflammation/Immunology

Reactive Oxygen Species (ROS) Autophagy Apoptosis VEGFR JAK Amyloid-β p38 MAPK HIF/HIF Prolyl-Hydroxylase STAT PI3K JNK Akt

Microorganisms Animals Cosmetic Research Disease Research Fields Saccharides Cancer

Endogenous Metabolite Bacterial PI3K Akt

Zea mays L. Moisture Plants Endogenous metabolite Human Gut Microbiota Metabolites Polysaccharides Gramineae Cosmetic Research Disease Research Fields Saccharides Cancer

Endogenous Metabolite Bacterial Akt PI3K

Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Inflammation/Immunology Araliaceae

NF-κB PI3K JAK Apoptosis

Infection Alkaloids Piperidine Alkaloids Leguminosae Plants Sophora flavescens Aiton Disease Research Fields Inflammation/Immunology

Autophagy Apoptosis NF-κB PI3K Akt MEK ERK PTEN

Cancer

Infection Alkaloids Piperidine Alkaloids Leguminosae Sophora japonica L. Plants Disease Research Fields Inflammation/Immunology

Autophagy Apoptosis NF-κB PI3K Akt MEK ERK

Alkaloids Ranunculaceae Phenols Polyphenols  Aconitum carmichaeli Debx. Plants Disease Research Fields Isoquinoline Alkaloids Endocrinology

MAP3K MDM-2/p53 Adrenergic Receptor ROS Kinase Apoptosis

Animals Disease Research Fields Cancer Steroids

PI3K Akt NF-κB AP-1 GSK-3 CDK

Other Diseases Amino acids Endogenous metabolite Disease Research Fields

Bacterial Arginase Akt

Cardiovascular Disease Infection Inflammation/Immunology

Animals Metabolic Disease Disease Research Fields Steroids

Calcium Channel Ferroptosis PI3K Reactive Oxygen Species (ROS) Akt HBV

Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology

Endogenous Metabolite Interleukin Related TNF Receptor AMPK Sirtuin STAT PI3K NF-κB JAK p38 MAPK JNK Akt Apoptosis Ferroptosis

Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology

Interleukin Related TNF Receptor Endogenous Metabolite AMPK Sirtuin STAT PI3K NF-κB JAK p38 MAPK JNK Akt Apoptosis Ferroptosis

Infection Monophenols Thymelaeaceae Coumarins Phenols Phenylpropanoids Plants Disease Research Fields Wikstroemia indica

PKC Influenza Virus NOD-like Receptor (NLR) Apoptosis HBV JNK PI3K Akt CDK Caspase Bcl-2 Family

Alkaloids Rutaceae Quinoline Alkaloids Plants Skimmia reevesiana Fort. Disease Research Fields Inflammation/Immunology

Cholinesterase (ChE) PI3K Akt NF-κB

Piperaceae Plants other families Flavonoids Chalcones Piper methysticum G.Forst. Phenols Polyphenols Disease Research Fields Cancer

Apoptosis Akt JNK PERK Caspase PARP MDM-2/p53 IAP Reactive Oxygen Species (ROS) SOD FABP Autophagy AMPK mTOR GLUT EGFR PI3K HSP VEGFR FAK

Stilbenes Gnetum cleistostachyum C. Y. Cheng Gnetaceae Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Carnitine Palmitoyltransferase (CPT) Reactive Oxygen Species (ROS) Autophagy Apoptosis NF-κB PI3K Akt MMP Keap1-Nrf2