1. Autophagy
    Apoptosis
    PI3K/Akt/mTOR
    Anti-infection
  2. Autophagy
    Apoptosis
    PI3K
    Akt
    Influenza Virus
  3. Sophocarpine monohydrate

Sophocarpine monohydrate 

Cat. No.: HY-N0103A Purity: >99.0%
Handling Instructions

Sophocarpine (monohydrate) is one of the significant alkaloid extracted from the traditional herb medicine Sophora flavescens which has many pharmacological properties such as anti-virus, anti-tumor, anti-inflammatory. Sophocarpine (monohydrate) significantly inhibits the growth of gastric cancer (GC) cells through multiple mechanisms such as induction of autophagy, activation of cell apoptosis and down-regulation of cell survival PI3K/AKT signaling pathway. Sophocarpine (monohydrate) has been demonstrated to have anti-tumor activity in various cancer cells, including hepatocellular carcinoma, prostate cancer and colorectal cancer.

For research use only. We do not sell to patients.

Sophocarpine monohydrate Chemical Structure

Sophocarpine monohydrate Chemical Structure

CAS No. : 145572-44-7

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10 mM * 1  mL in DMSO USD 55 Ask For Quote & Lead Time
5 mg USD 50 Ask For Quote & Lead Time
10 mg USD 80 Ask For Quote & Lead Time

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Description

Sophocarpine (monohydrate) is one of the significant alkaloid extracted from the traditional herb medicine Sophora flavescens which has many pharmacological properties such as anti-virus, anti-tumor, anti-inflammatory. Sophocarpine (monohydrate) significantly inhibits the growth of gastric cancer (GC) cells through multiple mechanisms such as induction of autophagy, activation of cell apoptosis and down-regulation of cell survival PI3K/AKT signaling pathway. Sophocarpine (monohydrate) has been demonstrated to have anti-tumor activity in various cancer cells, including hepatocellular carcinoma, prostate cancer and colorectal cancer[1].

IC50 & Target[1]

PI3K

 

Akt

 

Molecular Weight

264.36

Formula

C₁₅H₂₄N₂O₂

CAS No.

145572-44-7

SMILES

O=C1N(C[[email protected]@]2([H])[[email protected]@]3([H])[[email protected]]4([H])CCCN3CCC2)[[email protected]]4([H])CC=C1.O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References

Purity: >99.0%

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Keywords:

SophocarpineAutophagyApoptosisPI3KAktInfluenza VirusPhosphoinositide 3-kinasePKBProtein kinase BInhibitorinhibitorinhibit

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Sophocarpine monohydrate
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