1 Result for "

RAW-mLPCAT2 cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RAW-mLPCAT2 cells" in MCE Product Catalog:

Cat. No.: HY-112825
CAS No.: 704878-75-1
Purity:  98.52%
Research Areas:  

Inflammation/Immunology Cancer

TSI-01 is a selective LPCAT2 inhibitor, with IC50 values of 0.47 μM and 3.02 μM against LPCAT2 and LPCAT1, respectively. TSI-01 competitively inhibits acetyl-CoA (acetyl-CoA) targeting the lysophosphatidic acid acetyltransferase activity of LPCAT2, and suppresses PAF biosynthesis in calcium ionophore-stimulated mouse peritoneal macrophages. TSI-01 inhibits the proliferation of endometrial cancer cells and promotes endometrial cancer cell apoptosis (apoptosis). TSI-01 can be used for the research of endometrial cancer and PAF-related inflammatory diseases .
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