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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
RBL
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "RBL" in MCE Product Catalog:
2
Category:
Plants other families Flavonoids Functional Molecules Research of Health Products Phenols Polyphenols Disease Research Fields Inflammation/Immunology Biflavones
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2
2 Cited Publications
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Syk Inhibitor II is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II shows less potent against other kinases and has anti-allergic effect .
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1 Cited Publications
Synonyms: N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide
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Pyr6 is a selective store operated calcium entry (SOCE) inhibitor with an IC50 of 0.49 μM. Pyr6 displays 37-fold higher potency for RBL SOCE than for TRPC3 ROCE .
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1 Cited Publications
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15(S)-HETRE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid. It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 μM. In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.
Art. -Nr.: HY-113337A
CAS. Nr.: 102783-36-8
Synonyms: P1,P4-Di-(adenosine-5')-tetraphosphate tetraammonium
Ap4A tetraammonium (P1,P4-Di-(adenosine-5')-tetraphosphate tetraammonium) is a conserved second messenger in organisms ranging from bacteria to humans. Ap4A tetraammonium binds to the histidine triad nucleotide-binding protein 1 (HINT1) activates the transcription of genes downstream of MITF. Ap4A tetraammonium induces apoptosis .
Art. -Nr.: HY-N2252
CAS. Nr.: 51020-86-1
Synonyms: (+)-Licarin A
Category:
Neurological Disease Saururus chinensis (Lour.) Baill. Plants Saururaceae Monophenols Simple Phenylpropanols Phenols Phenylpropanoids Disease Research Fields Inflammation/Immunology
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FPL 62064 is a potent 5-lipoxygenase (5-LOX) and COX dual inhibitor, with IC50 values of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin synthetase (cyclooxygenase), respectively. FPL 62064 has potent anti-inflammatory activity .
Art. -Nr.: HY-P1640
CAS. Nr.: 130154-64-2
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NBI-42902 is an orally active, potent functional and competitive antagonist of GnRH receptor with an IC50 value of 0.79 nM, a Ki value of 0.56 nM, respectively. NBI-42902 inhibits GnRH-stimulated inositol phosphate (IP) accumulation, Ca 2+ flux, and ERK1/2 activation. NBI-42902 inhibits serum luteinizing hormone (LH) in castrated male macaques. NBI-42902 can be used for research on sex-hormone-related diseases .
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Art. -Nr.: HY-N15708
CAS. Nr.: 755036-45-4
Synonyms: (R)-(-)-Dichotomine C
Art. -Nr.: HY-112390
CAS. Nr.: 227449-73-2
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Syk Inhibitor II dihydrochloride is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II dihydrochloride inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II dihydrochloride shows less potent against other kinases and has anti-allergic effect .
Art. -Nr.: HY-RS11729
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RBL1 Human Pre-designed siRNA Set A contains three designed siRNAs for RBL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS11730
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RBL2 Human Pre-designed siRNA Set A contains three designed siRNAs for RBL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS27934
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Rbl2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Rbl2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-N12116
CAS. Nr.: 1967042-42-7
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Art. -Nr.: HY-139247
CAS. Nr.: 2454246-25-2
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pNPS-DHA (Compound 19) is an orally active DHA-ethanolamide (DHEA) derivative that has antiallergic activity. pNPS-DHA inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) reaction in mice. pNPS-DHA has anti-degranulating activity in RBL-2H3 mast cells with an IC50 of 15 μM .
Art. -Nr.: HY-P11128
CAS. Nr.: 1427516-68-4
Art. -Nr.: HY-N12231
CAS. Nr.: 75139-38-7
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Art. -Nr.: HY-N2344R
CAS. Nr.: 103883-03-0
Synonyms: Proanthocyanidin A1 (Standard)
Category:
other families Flavonoids Phenols Polyphenols Plants Biflavones
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
