18 Results for "

REF-1

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "REF-1" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-19357
CAS No.: 136164-66-4
Synonyms: E3330; APX-3330
Erenapursta (E3330) is a direct, orally active and selective inhibitor of Ape-1 (apurinic/apyrimidinic endonuclease 1)/Ref-1 (redox factor-1) redox. Erenapursta is able to impair tumor growth and blocks the activity of NF-κB, AP-1, and HIF-1α in pancreatic cancer. Erenapursta shows anticancer activities [1] .
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Cat. No.: HY-P11056
CAS No.: 1198397-79-3
Target:  

MDM-2/p53

Research Areas:  

Others

REF1 peptide is a PORK1 agonist with an EC50 of 0.028 nM in tomato. REF1 peptide binds to the extracellular domain of PORK1, triggers receptor autophosphorylation, and drives downstream MPK3/MPK6 activation, thereby initiating defense and regeneration signaling cascades. REF1 peptide induces callus formation, inhibits shoot regeneration upon continuous exposure, and enhances the regeneration and transformation efficiency of recalcitrant dicotyledonous and monocotyledonous crops [1] .
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Cat. No.: HY-120069
CAS No.: 1415030-15-7
Target:  

Apoptosis

Research Areas:  

Cancer

APX2009 is a specific APE1/REF-1 redox inhibitor with anticancer activities which decreases the proliferative, migratory, and invasive properties of breast cancer cell and induces apoptosis in breast cancer cell [1].
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Cat. No.: HY-15131
CAS No.: 550368-41-7
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

PNRI-299 is a selective AP-1 transcription inhibitor with an IC50 of 20 uM. PNRI-299 is a selective APE/Ref-1 inhibitor. PNRI-299 has no effect on NF-κB transcription or thioredoxin (up to 200 uM). PNRI-299 significantly reduces airway eosinophil infiltration, mucus hypersecretion, edema, and IL-4 levels in a mouse asthma model [1] .
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Cat. No.: HY-P84226
Synonyms: APE; APX; APE1; APEN; APEX; HAP1; REF1

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human, Rat, Monkey

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Cat. No.: HY-W997026
CAS No.: 66780-67-4
Target:  

Glucokinase

Research Areas:  

Metabolic Disease

Glucokinase activator 7 is a Glucokinase activator. Glucokinase activator 7 can be used for research of diabetes, hyperglycemia and other diseases (Compound in Page 176 of Ref.) .
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Cat. No.: HY-P84226A
Synonyms: APE; APX; APE1; APEN; APEX; HAP1; REF1

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human, Rat, Monkey

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Cat. No.: HY-176996
CAS No.: 1136839-60-5
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Ape1/Ref-1 redox-IN-1 (Compound 52) is an Ape1/Ref-1 redox inhibitor. Ape1/Ref-1 redox-IN-1 can be used in the research of cancer [1].
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Cat. No.: HY-P82375
Synonyms: APEX1; APE; APE1; APEX; APX; HAP1; REF1; DNA-(apurinic or apyrimidinic site) lyase; APEX nuclease; APEN; Apurinic-apyrimidinic endonuclease 1; AP endonuclease 1; APE-1; REF-1; Redox factor-1

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-RS14428
Research Areas:  

Others

TFPI2 Human Pre-designed siRNA Set A contains three designed siRNAs for TFPI2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS27998
Research Areas:  

Others

Apex1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Apex1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Cat. No.: HY-RS19247
Research Areas:  

Others

Alyref Mouse Pre-designed siRNA Set A contains three designed siRNAs for Alyref gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS00815
Research Areas:  

Others

APEX1 Human Pre-designed siRNA Set A contains three designed siRNAs for APEX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS14342
Research Areas:  

Others

TEAD1 Human Pre-designed siRNA Set A contains three designed siRNAs for TEAD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P87296
Synonyms: Placental protein 5 antibody; PP5 antibody; REF1 antibody; Retinal pigment epithelium cell factor 1 antibody; TFPI 2 antibody; TFPI-2 antibody; TFPI2 antibody; TFPI2 PEN antibody; TFPI2_HUMAN antibody; Tissue factor pathway inhibitor 2 antibody

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human

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Cat. No.: HY-RS21480
Research Areas:  

Others

Apex1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Apex1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P74527
Purity:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: Tissue factor pathway inhibitor 2; TFPI-2;
Species:  
Source:  
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Cat. No.: HY-P74528
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Tissue factor pathway inhibitor 2; TFPI-2;
Species:  
Source:  
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