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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
47 Results for "
RNA precursor
" in MedChemExpress (MCE) Product Catalog:
Products (47)
47 Results for "RNA precursor" in MCE Product Catalog:
8
8 Publications Verification
Synonyms: Cytosine β-D-riboside; Cytosine-1-β-D-ribofuranoside
5
5
5 Cited Publications
Cat. No.: HY-N0157A
CAS No.: 68399-76-8
Synonyms: 6-Carboxyuracil zinc; Vitamin B13 zinc
5
5 Cited Publications
Cat. No.: HY-N0157C
CAS No.: 24598-73-0
Synonyms: 6-Carboxyuracil potassium; Vitamin B13 potassium
4
4 Cited Publications
Cat. No.: HY-P1291
CAS No.: 201422-03-9
Target:
Research Areas:
4
4 Cited Publications
Cat. No.: HY-P1291A
Target:
Research Areas:
3
3 Cited Publications
Synonyms: Cytidine triphosphate; 5'-CTP
Category:
Infection Human Gut Microbiota Metabolites Natural Products Endogenous metabolite Disease Research Fields Cancer
Target:
3
Trimetrexate (CI-898) is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer .
3
3 Cited Publications
Cat. No.: HY-W013707
CAS No.: 81012-87-5
Synonyms: Cytidine triphosphate disodium dihydrate; 5'-CTP disodium dihydrate
Target:
Research Areas:
Cytidine-5'-triphosphate disodium dihydrate (Cytidine triphosphate disodium dihydrate) is a nucleoside triphosphate and a substrate of CMP-KDO synthase, forming CMP-KDO. Cytidine-5'-triphosphate disodium dihydrate is a precursor of RNA/DNA, phospholipids, and sialoglycoproteins, is reduced to dCTP by deoxycytidylate-generating reductase, and can be used for the biosynthesis of phosphatidic acid to CDP-DG/cardiolipin .
1
Target:
Research Areas:
Framycetin (Neomycin B), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections .
The product specifications provided below refer solely to the active content of Framycetin.
The product specifications provided below refer solely to the active content of Framycetin.
1
1 Cited Publications
Synonyms: Neomycin B sulfate; Fradiomycin B sulfate
Target:
Research Areas:
Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin sulfate competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin sulfate inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin sulfate, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections .
Cat. No.: HY-112747
CAS No.: 97281-51-1
Synonyms: LPI; PE (soy)
Target:
Research Areas:
Soy PE (LPI) is the most abundant phospholipid in prokaryotes and the second most abundant found in the membrane of mammalian, plant, and yeast cells, comprising approximately 25% of total mammalian phospholipids. In the brain, phosphatidylethanolamine comprises almost half of the total phospholipids. It is synthesized mainly through the cytidine diphosphate-ethanolamine and phosphatidylserine decarboxylation pathways, which occur in the endoplasmic reticulum (ER) and mitochondrial membranes, respectively. It is a precursor in the synthesis of phosphatidylcholine and arachidonoyl ethanolamide and is a source of ethanolamine used in various cellular functions. In E.coli, phosphatidylethanolamine deficiency prevents proper assembly of lactose permease, suggesting a role as a lipid chaperone. It is a cofactor in the propagation of prions in vitro and can convert recombinant mammalian proteins into infectious molecules even in the absence of RNA. This product contains phosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 and sn-2 positions .
The product specifications provided below refer solely to the active content of Soy PE.
The product specifications provided below refer solely to the active content of Soy PE.
Cat. No.: HY-W039722
CAS No.: 2341-22-2
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Research Areas:
5-Fluorocytidine is a member of cytidines, inhibits maturation of the 45S ribosomal RNA precursor .
Cat. No.: HY-177360
CAS No.: 3067915-73-2
Synonyms: RNA splicing modulator-4
Target:
Research Areas:
Ruxuplam (RNA splicing modulator-4) is an RNA splicing modulator. Ruxuplam controls the inclusion or exclusion of specific exons in precursor mRNA (pre-mRNA) by regulating alternative splicing events, thereby altering the coding sequence and function of mature mRNA. Ruxuplam shows promise for research into neurodegenerative diseases (such as Huntington's disease) and cancers .
Cat. No.: HY-B0158S7
Synonyms: Cytosine β-D-riboside-13C9; Cytosine-1-β-D-ribofuranoside-13C9
Research Areas:
Cytidine- 13C9 (Cytosine β-D-riboside- 13C9) is 13C labeled Cytidine (HY-B0158). Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .
The product specifications provided below refer solely to the active content of Cytidine- 13C9.
The product specifications provided below refer solely to the active content of Cytidine- 13C9.
Cat. No.: HY-B0158S6
Synonyms: Cytosine β-D-riboside-15N3; Cytosine-1-β-D-ribofuranoside-15N3
Synonyms: Cytosine β-D-riboside (Standard); Cytosine-1-β-D-ribofuranoside (Standard)
Cat. No.: HY-118723
CAS No.: 309726-06-5
Target:
Research Areas:
BMH-22, a benzonaphthyridin, is a RNA polymerase I (Pol I) transcription inhibitor independent of p53 function. BMH-22 causes reorganization of nucleolar marker proteins consistent with segregation of the nucleolus. BMH-22 destabilizes RPA194 in a proteasome-dependent manner and inhibits nascent rRNA synthesis and expression of the 45S rRNA precursor. BMH-22 shows potent anticancer activity across many tumor types .
Cat. No.: HY-B0158S1
CAS No.: 201996-57-8
Synonyms: Cytosine β-D-riboside-13C; Cytosine-1-β-D-ribofuranoside-13C
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
