1 Result for "

SVR angiosarcoma cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SVR angiosarcoma cells" in MCE Product Catalog:

Cat. No.: HY-16461
CAS No.: 137038-57-4
Synonyms: (-)-Solenopsin A
Solenopsin ((-)-Solenopsin A) is an ATP-competitive and selective Akt-1 inhibitor with an IC50 of 5-10 μM, and also acts as an RSK1 inhibitor. Solenopsin inhibits the activities of PDK1 in lipid rafts, downregulates PI3K, blocks PI3K-dependent generation of 3-phosphoinositides, and suppresses the phosphorylation of FOXO1a. Solenopsin induces Mitophagy and ROS production, reduces mitochondrial oxygen consumption, and exhibits antiproliferative and antiangiogenic activities. Solenopsin can be used in research related to hyperproliferative skin diseases and malignant diseases .
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