2821 Results for "

TYR

" in MedChemExpress (MCE) Product Catalog:
Products (2821)

2821 Results for "TYR" in MCE Product Catalog:

247
Angiotensin II human
Angiotensin II human
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247 Publications Verification
製品番号: HY-13948
CAS 番号: 4474-91-3
純度:  99.98%
別名: Angiotensin II; Ang II; DRVYIHPF
Category:  

天然物 Endogenous metabolite Disease Research Fields Endocrinology Cancer

Target:  

Angiotensin Receptor Apoptosis

Angiotensin II (Angiotensin II) is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human also induces apoptosis. Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway .
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247
Angiotensin II human acetate
Angiotensin II human acetate
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247 Publications Verification
製品番号: HY-13948A
CAS 番号: 68521-88-0
純度:  99.62%
別名: Angiotensin II acetate; Ang II acetate; DRVYIHPF acetate
Target:  

Angiotensin Receptor Apoptosis

研究分野:  

Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer

Angiotensin II human (Angiotensin II) acetate is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human acetate plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human acetate stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human acetate induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human acetate also induces apoptosis. Angiotensin II human acetate induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway .
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247
Angiotensin II human TFA
Angiotensin II human TFA
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247 Publications Verification
製品番号: HY-13948B
CAS 番号: 2761969-44-0
純度:  98.84%
別名: Angiotensin II TFA; Ang II TFA; DRVYIHPF TFA
Target:  

Angiotensin Receptor Apoptosis

研究分野:  

Cardiovascular Disease Metabolic Disease Cancer

Angiotensin II human (Angiotensin II) TFA is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human TFA plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human TFA stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human TFA induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human TFA also induces apoptosis. Angiotensin II human TFA induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway .
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142
Caerulein
Caerulein
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142 Cited Publications
製品番号: HY-A0190
CAS 番号: 17650-98-5
別名: Ceruletide; Cerulein; FI-6934
Category:  

Cardiovascular Disease Alkaloids Animals Disease Research Fields Endocrinology Indole Alkaloids

Target:  

Cholecystokinin Receptor

Caerulein is a decapeptide and a potent cholecystokinin receptor agonist. Caerulein is a safe and effective cholecystokinetic agent with a direct spasmogenic effect on the gallbladder muscle and bile ducts .
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99
Vancomycin
Vancomycin
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99 Cited Publications
製品番号: HY-B0671
CAS 番号: 1404-90-6
Category:  

Disease Research Antibacterial Endogenous metabolite Other Antibiotics Infection Human Gut Microbiota Metabolites Microorganisms Plant Cell Culture Antibiotics Disease Research Fields Cancer

Target:  

Bacterial Autophagy Antibiotic

Vancomycin is an antibiotic for the treatment of bacterial infections.
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59
Defactinib hydrochloride
Defactinib hydrochloride
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59 Cited Publications
製品番号: HY-12289A
CAS 番号: 1073160-26-5
純度:  99.35%
別名: VS-6063 hydrochloride; PF 04554878 hydrochloride
Target:  

FAK

研究分野:  

Cancer

Defactinib hydrochloride (VS-6063 hydrochloride; PF 04554878 hydrochloride) is a novel FAK inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.
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44
Semaglutide
Semaglutide
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44 Cited Publications
製品番号: HY-114118
CAS 番号: 910463-68-2
純度:  99.84%
Target:  

GLP Receptor Insulin Receptor α-synuclein Apoptosis p38 MAPK Autophagy Bcl-2 Family

研究分野:  

Neurological Disease Metabolic Disease Cancer

Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .
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44
Semaglutide TFA
Semaglutide TFA
0 Images
44 Cited Publications
製品番号: HY-114118A
純度:  99.92%
Target:  

GLP Receptor Insulin Receptor α-synuclein Apoptosis p38 MAPK Autophagy Bcl-2 Family

研究分野:  

Neurological Disease Metabolic Disease Cancer

Semaglutide TFA is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide TFA promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide TFA also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide TFA has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide TFA can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .
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44
Semaglutide acetate
Semaglutide acetate
0 Images
44 Cited Publications
製品番号: HY-114118B
CAS 番号: 1997361-85-9
純度:  99.92%
Target:  

GLP Receptor Insulin Receptor α-synuclein Apoptosis p38 MAPK Autophagy Bcl-2 Family

研究分野:  

Neurological Disease Metabolic Disease Cancer

Semaglutide acetate is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide acetate promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide acetate also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide acetate has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide acetate can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .
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42
Liraglutide
Liraglutide
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42 Cited Publications
製品番号: HY-P0014
CAS 番号: 204656-20-2
Target:  

GCGR GLP Receptor

研究分野:  

Metabolic Disease Cancer

Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.
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42
Liraglutide TFA
Liraglutide TFA
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42 Cited Publications
製品番号: HY-P0014B
Target:  

GLP Receptor

研究分野:  

Metabolic Disease

Liraglutide (TFA) is an agonist of glucagon-like peptide 1 receptor (GLP-1). Liraglutide (TFA) can activate GLP-1, leading to the release of insulin in the presence of increased glucose concentration. Liraglutide (TFA) also reduces glucagon secretion in a glucose-dependent manner. Liraglutide (TFA) can be studied in research on type 2 diabetes .
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32
Aprotinin
Aprotinin
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32 Cited Publications
製品番号: HY-P0017
CAS 番号: 9087-70-1
Category:  

Cardiovascular Disease 天然物 Animals Disease Research Fields

Target:  

Influenza Virus Ser/Thr Protease

Aprotinin is a bovine pancreatic trypsin inhibitor (BPTI) inhibitor which inhibits trypsin and chymotrypsin with Kis of 0.06 pM and 9 nM, respectively.
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31
3X FLAG peptide
3X FLAG peptide
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31 Cited Publications
製品番号: HY-P0319
CAS 番号: 402750-12-3
Target:  

Biochemical Assay Reagents

研究分野:  

Others

3X FLAG peptides are FLAG-tagged peptides containing three repeats of the Asp-Tyr-Lys-Xaa-Xaa-Asp motif. 3X FLAG peptide can be used for protein separation and purification, and competitive elution with target proteins.
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31
3X FLAG peptide TFA
3X FLAG peptide TFA
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31 Cited Publications
製品番号: HY-P0319A
Target:  

ペプチド

研究分野:  

Others

3X FLAG peptide TFA is a FLAG-tagged peptide containing three repeats of the Asp-Tyr-Lys-Xaa-Xaa-Asp motif. 3X FLAG peptide TFA can be used for protein separation and purification, and competitive elution with target proteins.
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28
Oxytocin
Oxytocin
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28 Cited Publications
製品番号: HY-17571
CAS 番号: 50-56-6
別名: α-Hypophamine; Oxytocic hormone
Category:  

天然物 Monophenols Animals Phenols Endogenous metabolite Disease Research Fields Endocrinology

Target:  

Oxytocin Receptor Endogenous Metabolite

Oxytocin (α-Hypophamine; Oxytocic hormone) is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma .
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28
Oxytocin acetate
Oxytocin acetate
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28 Cited Publications
製品番号: HY-17571A
CAS 番号: 6233-83-6
別名: α-Hypophamine acetate; Oxytocic hormone acetate
Category:  

天然物 Endogenous metabolite Disease Research Fields Endocrinology Cancer

Target:  

Oxytocin Receptor Endogenous Metabolite

Oxytocin (α-Hypophamine) acetate is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin acetate can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma .
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27
β-Amyloid (1-42), human TFA
β-Amyloid (1-42), human TFA
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27 Cited Publications
製品番号: HY-P1363
別名: Amyloid β-peptide (1-42) (human) TFA
Target:  

Amyloid-β

研究分野:  

Neurological Disease

β-Amyloid (1-42) (Amyloid β-peptide (1-42), human TFA, a 42-amino acid peptide that has not been treated with HFIP, is a brain-penetrant amyloid protein fragment, which can be used in research on Alzheimer's disease and Down’s syndrome. β-Amyloid (1-42), human TFA remaining as a monomer exhibits antioxidant and neuroprotective effects. β-Amyloid (1-42), human TFA, after being monomericized by HFIP and dissolved in DMSO to form the stock solution, on the one hand, can form soluble oligomers (AβOs) when incubated at 4 °C, which have synaptic toxicity and neurotoxicity; on the other hand, it can be incubated at 37 °C to form insoluble fibrils, with lower neurotoxicity, and participating in the oxidative damage process. Aβ42 oligomers bind to various neuronal surface receptors (such as PrPc, mGluR5, NMDA receptors, etc.), triggering oxidative stress, calcium homeostasis imbalance, and synaptic toxicity via activating downstream signaling pathways, leading to neuronal dysfunction and death .
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27
β-Amyloid (1-42), human
β-Amyloid (1-42), human
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27 Cited Publications
製品番号: HY-P1363A
CAS 番号: 107761-42-2
別名: Amyloid β-peptide (1-42) (human)
Target:  

Amyloid-β

研究分野:  

Neurological Disease

β-Amyloid (1-42) (Amyloid β-peptide (1-42)), human, a 42-amino acid peptide that has not been treated with HFIP, is a brain-penetrant amyloid protein fragment, which can be used in research on Alzheimer's disease and Down’s syndrome. β-Amyloid (1-42), human remaining as a monomer exhibits antioxidant and neuroprotective effects. β-Amyloid (1-42), human, after being monomericized by HFIP and dissolved in DMSO to form the stock solution, on the one hand, can form soluble oligomers (AβOs) when incubated at 4 °C, which have synaptic toxicity and neurotoxicity; on the other hand, it can be incubated at 37 °C to form insoluble fibrils, with lower neurotoxicity, and participating in the oxidative damage process. Aβ42 oligomers bind to various neuronal surface receptors (such as PrPc, mGluR5, NMDA receptors, etc.), triggering oxidative stress, calcium homeostasis imbalance, and synaptic toxicity via activating downstream signaling pathways, leading to neuronal dysfunction and death .
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27
β-Amyloid (1-42), human, HFIP-treated
β-Amyloid (1-42), human, HFIP-treated
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27 Cited Publications
製品番号: HY-P1363B
CAS 番号: 107761-42-2
Target:  

Amyloid-β

研究分野:  

Neurological Disease

β-Amyloid (1-42), human, HFIP-treated, a 42-amino acid peptide that has been treated with HFIP from β-Amyloid (1-42), human (HY-P1363A), is a brain-penetrant amyloid protein fragment, which can be used in research on Alzheimer's disease and Down’s syndrome. β-Amyloid (1-42), human, HFIP-treated remaining as a monomer exhibits antioxidant and neuroprotective effects. β-Amyloid (1-42), human, HFIP-treated, after being dissolved in DMSO to form the stock solution, on the one hand, can form soluble oligomers (AβOs) when incubated at 4°C, which have synaptic toxicity and neurotoxicity; on the other hand, it can be incubated at 37°C to form insoluble fibrils, with lower neurotoxicity, and participating in the oxidative damage process. Aβ42 oligomers bind to various neuronal surface receptors (such as PrPc, mGluR5, NMDA receptors, etc.), triggering oxidative stress, calcium homeostasis imbalance, and synaptic toxicity via activating downstream signaling pathways, leading to neuronal dysfunction and death .
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26
FLAG peptide
FLAG peptide
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26 Cited Publications
製品番号: HY-P0223
CAS 番号: 98849-88-8
Target:  

Biochemical Assay Reagents

研究分野:  

Inflammation/Immunology

FLAG peptide is a multifunctional fusion tag for the purification of recombinant proteins. FLAG peptide maintances the natural folding of its fusing proteins. FLAG peptide can be removed by enterokinase, and eluted under non-denaturing conditions .
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Assay Types