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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
81 Results for "
TfR
" in MedChemExpress (MCE) Product Catalog:
Products (81)
81 Results for "TfR" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-159569
CAS No.: 1643444-62-5
Research Areas:
TfR-1-IN-1 is a transferrin receptor-1 (TfR-1) inhibitor with tumor cell-specific activity. TfR-1-IN-1 reduces TfR-1 expression, impairs mitochondrial function, induces cell apoptosis, necroptosis and ferroptosis, and increases intracellular iron (II) levels. TfR-1-IN-1 decreases the metabolic activity of cancer cells. TfR-1-IN-1 can be used for the research of ovarian cancer, breast cancer and acute myeloid leukemia .
1
Category:
Infection Plant Phenols Polyphenols Rhamnus frangula Linn. Extract Disease Research Fields Rhamnaceae Extract
Target:
1
1 Cited Publications
Cat. No.: HY-P71069
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TfRC; Transferrin Receptor (P90, CD71); Transferrin Receptor; CD71 Antigen; P90; IMD46; Transferrin Receptor Protein 1; TRFR; CD71; Trfr; TfR1; TfR1; Transferrin Receptor 1; TfR; T9; TfR; TR
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P73453
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TF; Epididymis Secretory Sperm Binding Protein Li 71p; Transferrin; CDNA FLJ54029, Highly Similar To Serotransferrin; Serotransferrin; Transferrin, Isoform CRA_c; Beta-1 Metal-Binding Globulin; TF Protein; Siderophilin; HEL-S-71p; PRO1557; TFQTL1; PRO2086
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P9999
CAS No.: 2568868-35-7
Synonyms: RG6102; RO-7126209
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Cat. No.: HY-P991047
Synonyms: JR-141 antibody (uncoupled from iduronate 2-sulfatase)
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Cat. No.: HY-172723
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DSPE-PEG2000-T7 is a PEGylated compound composed of DSPE and peptideT7. T7 (HAIYPRH) specifically binds to TfR. DSPE-PEG2000-T7 can be used to prepare T7-modified liposomes, where liposomes modified with both T7 and DA7R peptides can effectively co-deliver Doxorubicin (HY-15142A) and Vincristine (HY-N0488A) to gliomas. DSPE-PEG2000-T7 can also be used to prepare nanomodulators that mediate the co-delivery of tyrosine hydroxylase mRNA and interferon gene stimulator antagonists for synergistic intervention in Parkinson's disease .
Cat. No.: HY-P2297
CAS No.: 344618-30-0
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Cat. No.: HY-P11099
CAS No.: 1254540-73-2
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Cat. No.: HY-177565
CAS No.: 2653183-68-5
Synonyms: Del-desiran; AOC 1001
Research Areas:
Delpacibart braxlosiran (Del-desiran), an antibody oligonucleotide conjugate (AOC), consists of a monoclonal antibody (Delpacibart) (HY-P990051) that binds to the transferrin receptor 1 (TfR1) conjugated with a siRNA targeting DMPK (DM1 protein kinase) mRNA. Delpacibart braxlosiran is used for the study of myotonic dystrophy type 1 (DM1) .
Cat. No.: HY-P990129
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Cat. No.: HY-P2314
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Cat. No.: HY-P991381
Synonyms: PPMX-T003; TSP-A18
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Cat. No.: HY-P990130
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Cat. No.: HY-P990856
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Cat. No.: HY-177564
CAS No.: 2929240-20-8
Synonyms: Del-zota; AOC 1044
Target:
Antibody-Oligonucleotide Conjugates (AOCs) Transferrin Receptor Dystrophin Antibody-Drug Conjugates (ADCs)
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Delpacibart zotadirsen (Del-zota), an antibody oligonucleotide conjugate (AOC), consists of a monoclonal antibody (Delpacibart) (HY-P990051) that binds to the transferrin receptor 1 (TfR1) conjugated to a phosphorodiamidate morpholino conjugate (PMO), Delpacibart zotadirsen is designed to deliver phosphorodiamidate morpholino oligomers (PMOs) to skeletal muscle and heart tissue to specifically skip exon 44 of the dystrophin gene and enable production of near-full length dystrophin. Delpacibart zotadirsen is used for the study of myotonic dystrophy type 1 (DM1) .
Cat. No.: HY-P990791
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Cat. No.: HY-RS21441
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Tfr2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tfr2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-177454
CAS No.: 2763758-01-4
Research Areas:
Basivarsen linker is a linker used in HY-177452 Zeleciment basivarsen for coupling a TfR1-binding Fab Zeleciment (HY-P990780) and an antisense oligonucleotide. Zeleciment basivarsen is an antibody-oligonucleotide conjugate (AOC) designed to target mutant nuclear myotonic dystrophy protein kinase (DMPK) RNA for RHase H-mediated degradation to correct splicing. It is used for the study of myotonic dystrophy type 1 (DM1).
Cat. No.: HY-RS14431
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TFRC Human Pre-designed siRNA Set A contains three designed siRNAs for TFRC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
