37 Results for "

acetaldehyde

" in MedChemExpress (MCE) Product Catalog:
Products (37)

37 Results for "acetaldehyde" in MCE Product Catalog:

18
18 Cited Publications
Cat. No.: HY-113466
CAS No.: 75899-68-2
Purity:  99.35%
Synonyms: 4-HNE
4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). 4-Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4-Hydroxynonenal plays an important role in cancer through mitochondria .
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4
4 Cited Publications
Cat. No.: HY-B1429
CAS No.: 94-20-2
Target:  

Na+/K+ ATPase

Research Areas:  

Metabolic Disease Endocrinology

Chlorpropamide is an oral hypoglycemic agent that can influence acetaldehyde metabolism in mice and has a potentiating effect on antidiuretic hormone .
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Cat. No.: HY-N0538
CAS No.: 87-99-0
Synonyms: Xylite
Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy (Autophagy) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model .
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Cat. No.: HY-W004661
CAS No.: 23147-58-2
Synonyms: Hydroxy acetaldehyde
1,4-Dioxane-2,5-diol is an endogenous metabolite.
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Cat. No.: HY-W015969
CAS No.: 78-96-6
Synonyms: Monoisopropanolamine
1-Aminopropan-2-ol is a microbial metabolism of amino alcohol metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas .
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Cat. No.: HY-A0060
CAS No.: 59937-28-9
Synonyms: NKK 105
Target:  

Lipoxygenase

Research Areas:  

Cancer

Malotilate (NKK 105), an orally active hepatotropic agent and an anti-fibrotic substance, selectively inhibits the 5-lipoxygenase (5-LOX) (IC50=4.7 μM). Malotilate prevents the development of hepatocytic injury in alcohol-pyrazole hepatitis by decreasing hepatic acetaldehyde levels and preventing the retention of transferrin in the hepatocytes .
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Cat. No.: HY-W012874
CAS No.: 632-20-2
Synonyms: H-D-Thr-OH
D-Threonine (H-D-Thr-OH) is one of the important unnatural amino acids used as chiral building blocks in pharmaceutical drugs. D-Threonine is a metabolite of Saccharomyces cerevisiae. D-Threonine is cleaved into glycine and acetaldehyde by the catalytic action of D-threonine aldolase .
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Cat. No.: HY-122373
CAS No.: 58919-61-2
Coprine is an orally active disulfiram (HY-B0240)-like component and an inhibitor of aldehyde dehydrogenase. Coprine is isolated from Coprinus atranentarius. Coprine inhibits low Km aldehyde dehydrogenase in rat liver and increases blood acetaldehyde levels during in vivo ethanol metabolism. Coprine does not inhibit semi-purified low Km aldehyde dehydrogenase from rat liver in vitro. Coprine can be used in studies related to alcoholism .
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Cat. No.: HY-147240
CAS No.: 1824609-67-7
Purity:  99.92%
Synonyms: ADX-629
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Acloproxalap (ADX-629) is an orally active reactive aldehyde species (RASP) inhibitor. Acloproxalap binds covalently to free aldehydes, sequesters reactive aldehyde species, malondialdehyde, acetaldehyde and preformed malondialdehyde-acetaldehyde adducts, and reduces elevated RASP levels. Acloproxalap decreases the formation of aldehyde adducts, reduces liver and serum triglyceride levels, hepatic fat accumulation, circulating anti-malondialdehyde-acetaldehyde adduct antibody levels, and inhibits the release of IL-6 and MCP-1. Acloproxalap improves cell viability of liver slices exposed to ethanol. Acloproxalap blocks ethanol-induced damage in animal models of alcoholic liver disease. Acloproxalap is applicable to research related to alcoholic liver disease, alcoholic fatty liver disease, non-alcoholic steatohepatitis, chronic cough, rheumatoid arthritis, ulcerative colitis and mild atopic asthma .
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Cat. No.: HY-100061A
CAS No.: 125969-54-2
Purity:  99.71%
Target:  

Drug Intermediate

Research Areas:  

Others

2-(Dimethylamino)acetaldehyde hydrochloride is a chemical intermediate. 2-(Dimethylamino)acetaldehyde hydrochloride can be used to synthesis Muscarine analogues .
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Cat. No.: HY-113466S
CAS No.: 148706-06-3
Purity:  99.0%
Synonyms: 4-HNE-d3
4-Hydroxynonenal-d3 is the deuterium labeled 4-Hydroxynonenal. 4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). 4-Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4-Hydroxynonenal plays an important role in cancer through mitochondria .
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Cat. No.: HY-75884
CAS No.: 2136-75-6
2-(Triphenylphosphoranylidene)acetaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-P2796
CAS No.: 9001-04-1
Synonyms: PDC
Research Areas:  

Metabolic Disease

Pyruvate decarboxylase (PDC) is an enzyme that catalyses the decarboxylation of pyruvic acid to acetaldehyde. Pyruvate decarboxylase catalyses the non-oxidative conversion of pyruvate (or other 2-oxo acids) to acetaldehyde and CO2 .
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Cat. No.: HY-126241
CAS No.: 1016897-10-1
Purity:  98.0%
Research Areas:  

Inflammation/Immunology

RV01 is an analogue of resveratrol, inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol, and exhibits hydroxyl radical scavenging activity . RV01 decreases iNOS expression, with anti-neuroinflammatory activity .
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Cat. No.: HY-34409
CAS No.: 107-86-8
Synonyms: 3-Methylbut-2-en-1-al
3-Methyl-2-butenal (3-Methylbut-2-en-1-al) is an enone aldehyde that occurs in hops (Humulus lupulus L.) .
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Cat. No.: HY-P2740B
CAS No.: 9031-72-5
Research Areas:  

Metabolic Disease

Alcohol dehydrogenase, yeast is an alcohol dehydrogenase expressed in yeast. It can catalyze the conversion between ethanol and acetaldehyde, while also reducing NAD or NADP, and it plays a role in glycolysis and aerobic respiration .
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Cat. No.: HY-N1177
CAS No.: 514-07-8
Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively .
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Cat. No.: HY-100061
CAS No.: 52334-92-6
Target:  

Drug Intermediate

Research Areas:  

Others

2-(Dimethylamino)acetaldehyde can be used to synthesis Muscarine analogues .
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Cat. No.: HY-W998295
CAS No.: 2736510-47-5
Research Areas:  

Cancer

E3 ligase Ligand PG-piperidine-acetaldehyde is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
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Cat. No.: HY-P4308
CAS No.: 170116-63-9
Research Areas:  

Neurological Disease

Z-Pro-Pro-aldehyde-dimethyl acetal is a potent inhibitor of prolyl endopeptidase (PREP), a cytoplasmic serine endoprotease (IC50= 12 nM). Z-Pro-Pro-aldehyde-dimethyl acetal plays an important role in cognitive dysfunction in aging and neurodegenerative diseases including Alzheimer's disease .
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