45 Results for "

acetaldehyde

" in MedChemExpress (MCE) Product Catalog:
Products (45)

45 Results for "acetaldehyde" in MCE Product Catalog:

18
18 Cited Publications
製品番号: HY-113466
CAS 番号: 75899-68-2
純度:  99.35%
別名: 4-HNE
4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). 4-Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4-Hydroxynonenal plays an important role in cancer through mitochondria .
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4
4 Cited Publications
製品番号: HY-B1429
CAS 番号: 94-20-2
Target:  

Na+/K+ ATPase

研究分野:  

Metabolic Disease Endocrinology

Chlorpropamide is an oral hypoglycemic agent that can influence acetaldehyde metabolism in mice and has a potentiating effect on antidiuretic hormone .
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製品番号: HY-N0538
CAS 番号: 87-99-0
別名: Xylite
Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy (Autophagy) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model .
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製品番号: HY-W004661
CAS 番号: 23147-58-2
別名: Hydroxy acetaldehyde
1,4-Dioxane-2,5-diol (Hydroxy Acetaldehyde) is an endogenous metabolite .
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製品番号: HY-W015969
CAS 番号: 78-96-6
別名: Monoisopropanolamine
1-Aminopropan-2-ol is a microbial metabolism of amino alcohol metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas .
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製品番号: HY-A0060
CAS 番号: 59937-28-9
別名: NKK 105
Target:  

Lipoxygenase

研究分野:  

Cancer

Malotilate (NKK 105), an orally active hepatotropic agent and an anti-fibrotic substance, selectively inhibits the 5-lipoxygenase (5-LOX) (IC50=4.7 μM). Malotilate prevents the development of hepatocytic injury in alcohol-pyrazole hepatitis by decreasing hepatic acetaldehyde levels and preventing the retention of transferrin in the hepatocytes .
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製品番号: HY-W012874
CAS 番号: 632-20-2
別名: H-D-Thr-OH
D-Threonine (H-D-Thr-OH) is an important non-natural amino acid. D-Threonine serves as a chiral building block for the asymmetric synthesis of compounds. D-Threonine is a metabolite of Saccharomyces cerevisiae. D-Threonine is cleaved into glycine and acetaldehyde under the catalysis of D-threonine aldolase .
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製品番号: HY-P1775A
CAS 番号: 9001-03-0
Carbonic anhydrase isoenzyme is an isoform of Carbonic anhydrase (HY-P1775). Carbonic anhydrase isoenzymes are a class of widely distributed metalloenzymes that catalyze the reversible hydration-dehydration reaction of the carbon dioxide-bicarbonate system, and also exhibit acetaldehyde hydration and ester hydrolysis activities. Carbonic anhydrase isoenzyme is associated with epithelial ion transport processes involving sodium, potassium, anions, and ammonia. Carbonic anhydrase isoenzyme can be used in research on cancer, glaucoma, obesity, and epilepsy .
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製品番号: HY-122373
CAS 番号: 58919-61-2
Coprine is an orally active disulfiram (HY-B0240)-like component and an inhibitor of aldehyde dehydrogenase. Coprine is isolated from Coprinus atranentarius. Coprine inhibits low Km aldehyde dehydrogenase in rat liver and increases blood acetaldehyde levels during in vivo ethanol metabolism. Coprine does not inhibit semi-purified low Km aldehyde dehydrogenase from rat liver in vitro. Coprine can be used in studies related to alcoholism .
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製品番号: HY-147240
CAS 番号: 1824609-67-7
純度:  99.92%
別名: ADX-629
Target:  

Interleukin Related

研究分野:  

Inflammation/Immunology

Acloproxalap (ADX-629) is an orally active reactive aldehyde species (RASP) inhibitor. Acloproxalap binds covalently to free aldehydes, sequesters reactive aldehyde species, malondialdehyde, acetaldehyde and preformed malondialdehyde-acetaldehyde adducts, and reduces elevated RASP levels. Acloproxalap decreases the formation of aldehyde adducts, reduces liver and serum triglyceride levels, hepatic fat accumulation, circulating anti-malondialdehyde-acetaldehyde adduct antibody levels, and inhibits the release of IL-6 and MCP-1. Acloproxalap improves cell viability of liver slices exposed to ethanol. Acloproxalap blocks ethanol-induced damage in animal models of alcoholic liver disease. Acloproxalap is applicable to research related to alcoholic liver disease, alcoholic fatty liver disease, non-alcoholic steatohepatitis, chronic cough, rheumatoid arthritis, ulcerative colitis and mild atopic asthma .
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製品番号: HY-100061A
CAS 番号: 125969-54-2
純度:  99.71%
Target:  

Drug Intermediate

研究分野:  

Others

2-(Dimethylamino)acetaldehyde hydrochloride is a chemical intermediate. 2-(Dimethylamino)acetaldehyde hydrochloride can be used to synthesis Muscarine analogues .
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製品番号: HY-113466S
CAS 番号: 148706-06-3
純度:  99.0%
別名: 4-HNE-d3
4-Hydroxynonenal-d3 is the deuterium labeled 4-Hydroxynonenal. 4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). 4-Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4-Hydroxynonenal plays an important role in cancer through mitochondria .
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製品番号: HY-75884
CAS 番号: 2136-75-6
2-(Triphenylphosphoranylidene)acetaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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製品番号: HY-P2796
CAS 番号: 9001-04-1
別名: PDC
研究分野:  

Metabolic Disease

Pyruvate decarboxylase (PDC) is an enzyme that catalyses the decarboxylation of pyruvic acid to acetaldehyde. Pyruvate decarboxylase catalyses the non-oxidative conversion of pyruvate (or other 2-oxo acids) to acetaldehyde and CO2 .
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製品番号: HY-126241
CAS 番号: 1016897-10-1
純度:  98.0%
RV01 is an analogue of resveratrol, inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol, and exhibits hydroxyl radical scavenging activity . RV01 decreases iNOS expression, with anti-neuroinflammatory activity .
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製品番号: HY-W001959
CAS 番号: 24830-94-2
D-Allothreonine is a non-proteinogenic amino acid that serves as a substrate for Pyridoxal phosphate (HY-B1744)-dependent D-threonine aldolase, being cleaved into Glycine (HY-Y0966) and acetaldehyde, and acts as a constituent of bioactive peptidyl natural products such as callipeltins, conferring protease resistance. D-Allothreonine is used in natural product synthesis and metabolic research .
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製品番号: HY-N1177
CAS 番号: 514-07-8
Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively .
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製品番号: HY-100061
CAS 番号: 52334-92-6
Target:  

Drug Intermediate

研究分野:  

Others

2-(Dimethylamino)acetaldehyde is a chemical intermediate. 2-(Dimethylamino)acetaldehyde can be used to synthesis Muscarine analogues .
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製品番号: HY-W998295
CAS 番号: 2736510-47-5
研究分野:  

Cancer

E3 ligase Ligand PG-piperidine-acetaldehyde is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
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製品番号: HY-P4308
CAS 番号: 170116-63-9
研究分野:  

Neurological Disease

Z-Pro-Pro-aldehyde-dimethyl acetal is a potent inhibitor of prolyl endopeptidase (PREP), a cytoplasmic serine endoprotease (IC50= 12 nM). Z-Pro-Pro-aldehyde-dimethyl acetal plays an important role in cognitive dysfunction in aging and neurodegenerative diseases including Alzheimer's disease .
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