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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
43 Results for "
actin binding
" in MedChemExpress (MCE) Product Catalog:
Products (43)
43 Results for "actin binding" in MCE Product Catalog:
100
100 Publications Verification
Cat. No.: HY-N6682
CAS No.: 22144-77-0
Synonyms: Zygosporin A; NSC 209835
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10
10 Cited Publications
Cat. No.: HY-P80438
Synonyms: A26C1A antibody;
A26C1B antibody;
ACTB antibody;
ACTB_HUMAN antibody;
actin beta antibody;
actin cytoplasmic 1 antibody;
actin, cytoplasmic 1, N-terminally processed antibody;
Actx antibody;
b actin antibody;
Beta cytoskeletal actin antibody;
Beta-actin antibody;
BRWS1 antibody;
E430023M04Rik antibody;
MGC128179 antibody;
PS1TP5 binding protein 1 antibody;
PS1TP5BP1 antibody;
β-actin antibody
5
1
1 Cited Publications
Cat. No.: HY-P0170
CAS No.: 885340-08-9
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Cat. No.: HY-P2031
CAS No.: 26645-35-2
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Ganglioside GM2 is a human tumor antigen predominantly found in human tumor cells and fetal brain tissue. As a sialylated glycosphingolipid, Ganglioside GM2 is involved in processes such as cell signaling, adhesion, and motility. Ganglioside GM2 abnormal expression and accumulation are associated with tumors and neurodegenerative disorders. Ganglioside GM2 promotes tumor cell migration and invasion by directly binding to the integrin β1 receptor, activating the FAK/Src/Erk-MAPK signaling pathway, and inducing actin cytoskeleton remodeling .
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Gamendazole, an indazole carboxylic acid (ICA), is an orally active, selective HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A) inhibitor. Gamendazole binds to the C-terminal nucleotide binding pocket of HSP90 and cause downregulation of clients AKT1 and ERBB2, but stabilizes the HSP90 heterocomplex. Gamendazole specifically inhibits the actin bundling function of EEF1A1, but does not bind to the nucleotide docking pocket nor inhibits the ribosome charging or protein translation functions of EEF1A1. Gamendazole, an antispermatogenic compound with antifertility effects, has the potential for reversible non-hormonal male contraceptive agent research .
Cat. No.: HY-P2463
CAS No.: 476014-70-7
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Cat. No.: HY-P11112
CAS No.: 1609454-11-6
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TR-100 is a small molecule inhibitor of tumor-associated troponin (Tpm). TR-100 affects the interaction of Tpm3.1 with actin filaments by binding to the C-terminal of Tpm3.1, thereby affecting the stability and function of the actin filaments. This mechanism of action allows TR-100 to specifically affect actin filaments in cancer cells without compromising heart muscle function. TR-100 can be used to study the role of Tpm3.1 in cancer cell proliferation and survival and the effects of Tpm3.1 on insulin-stimulated glucose uptake and insulin secretion .
Cat. No.: HY-P3828
CAS No.: 923949-88-6
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Cat. No.: HY-P991423
Synonyms: 21H3RK
Cat. No.: HY-175753
CAS No.: 2094958-44-6
Z17544625 is a Fascin inhibitor. Z17544625 has a strong binding capacity to fascin and inhibits Actin bundling. Z17544625 significantly reduces proliferation and impairs migration of CRC cells. Z17544625 can be used for cancer, especially colorectal cancer (CRC) research .
Cat. No.: HY-P10651
CAS No.: 1158186-08-3
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Cat. No.: HY-121352
CAS No.: 934464-79-6
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Kibdelone C is a hexacyclic tetrahydroxanthone natural product and anticancer agent with sub-nanomolar GI50 activity against human SR leukemia and SN12C renal carcinoma cell lines. Kibdelone C disrupts the actin cytoskeleton in human cancer cells, leading to cell contraction and actin stress fiber formation, without direct actin binding, actin polymerization effects, topoisomerase I/II inhibition, or DNA binding. Kibdelone C can be used for the research of leukemia, and renal cell carcinoma .
Cat. No.: HY-121490
CAS No.: 218929-99-8
IMM-02 is a DID-DAD binding inhibitor with activity promoting actin assembly and microtubule stabilization. IMM-02 is able to trigger serum response factor-mediated gene expression and lead to cell cycle arrest and apoptosis. IMM-02 has shown the ability to slow tumor growth in a mouse colon cancer xenograft model .
Cat. No.: HY-152003S
CAS No.: 2692623-87-1
Cat. No.: HY-P703323
Synonyms: Myosin-IIIa; MYO3A; Homo sapiens; Human; actin-binding; Kinase; Motor protein; Myosin; Serine/threonine-protein kinase; Transferase; 2.7.11.1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
