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Results for "

alkaline

" in MedChemExpress (MCE) Product Catalog:

258

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44

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49

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12

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3

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1

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41

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21

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10

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23

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0852
    Sodium orthovanadate
    10+ Cited Publications

    Phosphatase Cancer
    Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue.
    Sodium orthovanadate
  • HY-P2818
    Alkaline phosphatase, Bovine intestine
    1 Publications Verification

    Apase

    Endogenous Metabolite Phosphatase Glutathione Peroxidase Bacterial Infection Inflammation/Immunology
    Alkaline phosphatase, Bovine intestine (Apase) is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase, Bovine intestine reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase, Bovine intestine improves survival rate of mice infected with E. coli. Alkaline phosphatase, Bovine intestine improves TNBS-induced colon inflammation .
    Alkaline phosphatase, Bovine intestine
  • HY-D0994
    4-Methylumbelliferyl phosphate
    1 Publications Verification

    4-MUP; MUP

    Phosphatase Others
    4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant .
    4-Methylumbelliferyl phosphate
  • HY-15928
    4-Nitrophenyl phosphate disodium
    1 Publications Verification

    p-Nitrophenyl phosphate disodium

    Fluorescent Dye Others
    4-Nitrophenyl phosphate (p-Nitrophenyl phosphate) disodium is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays.
    4-Nitrophenyl phosphate disodium
  • HY-P2818E
    Alkaline Phosphatase, Calf intestinal
    1 Publications Verification

    Apase, Calf intestinal

    Endogenous Metabolite Phosphatase Glutathione Peroxidase Bacterial Infection Inflammation/Immunology
    Alkaline Phosphatase (Apase), Calf intestinal is an alkaline phosphatase from Calf intestinal, and is one of the most active alkaline phosphatases. Alkaline Phosphatase, Calf intestinal is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline Phosphatase, Calf intestinal reduces myeloperoxidase activity and bacterial translocation. Alkaline Phosphatase, Calf intestinal improves survival rate of mice infected with E. coli. Alkaline Phosphatase, Calf intestinal improves TNBS-induced colon inflammation .
    Alkaline Phosphatase, Calf intestinal
  • HY-Y1422

    alkaline lipase

    Environmental Pollutants Lipase Metabolic Disease
    Triacylglycerol lipase is an enzyme catalyzing the hydrolysis of triacylglycerol. Triacylglycerol lipase promotes fat decomposition, providing energy and lipid precursors for cells. Triacylglycerol lipase is used in the research of metabolic diseases such as diabetes and obesity .
    Triacylglycerol lipase
  • HY-D0211
    Phenolphthalein
    1 Publications Verification

    Fluorescent Dye Cancer
    Phenolphthalein is an acid-base indicator that is colorless in an acidic environment and pink in an alkaline environment. Phenolphthalein is genotoxic and potentially carcinogenic to mice. In addition, phenolphthalein is also a blood indicator .
    Phenolphthalein
  • HY-Y0319B
    Acetic acid (potassium 99%)
    1 Publications Verification

    Potassium acetate

    Environmental Pollutants Biochemical Assay Reagents Infection Cancer
    Acetic acid potassium 99% (Potassium acetate) is a potassium salt employed to replenish electrolytes, for restoration of water-electrolyte balance. Acetic acid potassium 99% can employ in DNA and protein purification. Acetic acid potassium 99% has been used to prepare neutralizing solution for alkaline lysis of bacteria and activated carbon .
    Acetic acid (potassium 99%)
  • HY-W007599

    Drug Derivative Cancer
    (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid is a polypeptide derivative, can be used to synthesis multifunctional amphiphilic peptide dendrimer for non-viral gene delivery in cancer research. (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid can be used in the preparation of organic substances that enhance the luminescence intensity of alkaline phosphatase substrates .
    (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid
  • HY-15909

    BCIP p-toluidine salt; X-phosphate p-toluidine salt

    Fluorescent Dye Others
    BCIP(BCIP p-toluidine salt; X-phosphate p-toluidine salt) is an artificial chromogenic substrate used for the sensitive colorimetric detection of alkaline phosphatase activity .
    BCIP
  • HY-19695
    (-)-p-Bromotetramisole oxalate
    1 Publications Verification

    L-p-Bromotetramisole oxalate; 6-Bromolevamisole oxalate

    Phosphatase Cancer
    (-)-p-Bromotetramisole oxalate (L-p-Bromotetramisole oxalate) is an alkaline phosphatase inhibitor. (-)-p-Bromotetramisole (oxalate) is applicable to research related to erythroleukemia .
    (-)-p-Bromotetramisole oxalate
  • HY-P2818C
    Alkaline phosphatase, microorganism
    1 Publications Verification

    Apase, microorganism

    Endogenous Metabolite Phosphatase Glutathione Peroxidase Bacterial Infection Inflammation/Immunology
    Alkaline Phosphatase (Apase), microorganism is an alkaline phosphatase from microorganism, and is one of the most active alkaline phosphatases. Alkaline phosphatase, microorganism is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase, microorganism reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase, microorganism improves survival rate of mice infected with E. coli. Alkaline phosphatase, microorganism improves TNBS-induced colon inflammation .
    Alkaline phosphatase, microorganism
  • HY-P2818A
    Alkaline phosphatase, Escherichia coli
    1 Publications Verification

    Apase, Escherichia coli

    Endogenous Metabolite Phosphatase Glutathione Peroxidase Bacterial Infection Inflammation/Immunology
    Alkaline Phosphatase (Apase), Escherichia coli is an alkaline phosphatase from Escherichia coli, and is one of the most active alkaline phosphatases. Alkaline phosphatase, Escherichia coli is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase, Escherichia coli reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase, Escherichia coli improves survival rate of mice infected with E. coli. Alkaline phosphatase, Escherichia coli improves TNBS-induced colon inflammation .
    Alkaline phosphatase, Escherichia coli
  • HY-Y1242

    Environmental Pollutants Biochemical Assay Reagents Others
    Choline hydroxide is a Choline hydrogen oxidized derivative and a strong organic base, can be used as the standard alkaline to adjust the pH of the medium. Choline is an orally active nutrient, serves as an important component of lecithin and sphingomyelin, promotes fat metabolism .
    Choline hydroxide (44% in water)
  • HY-D1491A

    Fluorescent Dye Others
    Fast Red Violet LB Zinc chloride is a stain that stains tartrate-resistant acid phosphatase (TRAP) and Fast Red Violet LB Zinc chloride can be used to stain alkaline phosphatase (ALP) activity .
    Fast Red Violet LB Zinc chloride
  • HY-21196A

    Phosphatase Metabolic Disease
    Potassium perfluorohexanesulfonate is an orally active surfactant found in sera of the general population. Potassium perfluorohexanesulfonate induces adaptive hepatocellular hypertrophy, decreases serum cholesterol and increases alkaline phosphatase in male mice .
    Potassium perfluorohexanesulfonate
  • HY-D0220A
    Toluidine Blue (purity 36%)
    3 Publications Verification

    Toluidine Blue O (purity 36%)

    Fluorescent Dye Others Cancer
    Toluidine Blue (Toluidine Blue O) purity 36% is an alkaline quinonimine dye (vivo dye) with high affinity for acidic tissue components, staining nuclei blue and polysaccharides purple. Toluidine Blue purity 36% shows heterostaining properties for mast cells, mucins and chondrocytes. Toluidine Blue purity 36% can stain different components of plant tissues and cells in different colours. Toluidine Blue purity 36% is also used as a diagnostic aid to identify malignant lesions, such as cancer .
    Toluidine Blue (purity 36%)
  • HY-W013755
    Dioctyl phthalate
    2 Publications Verification

    DNOP; Di-n-octyl phthalate; Phthalic acid dioctyl ester

    Biochemical Assay Reagents Aminotransferases (Transaminases) Phosphatase Bacterial Inflammation/Immunology
    Dioctyl phthalate (DNOP) is a plasticizer. Dioctyl phthalate increases the activities of alanine aminotransferase (ALT) and alkaline phosphatase (ALP) in the liver, as well as the levels of creatinine and urea in the kidney. Exposure to Dioctyl phthalate disrupts the homeostasis of the intestinal microbial community, increases the abundance of pathogenic bacteria, and reduces the abundance of beneficial bacteria such as Lactobacillus. Dioctyl phthalate induces significant and dose-dependent inflammatory responses in the liver, spleen and kidney of mice .
    Dioctyl phthalate
  • HY-D1208

    Biochemical Assay Reagents Phosphatase Others
    Alkaline phosphatase substrate is a chemiluminescent substrate for alkaline phosphatase. Alkaline phosphatase substrate can be used for enzyme-linked immunoassays .
    Alkaline phosphatase substrate
  • HY-P5832

    TGF-beta/Smad RUNX Metabolic Disease
    BMP2-derived peptide is an osteogenic inducer and BMP receptor ligand. BMP2-derived peptide binds to BMP receptors on the cell surface to form a complex, activates the downstream Smad signaling pathway, and regulates the expression of osteogenic transcription factors. BMP2-derived peptide effectively promotes the adhesion, proliferation, osteogenic differentiation and mineralization of bone marrow mesenchymal stem cells, significantly up-regulates the mRNA levels of OCN, Runx2 and type I collagen, and increases alkaline phosphatase activity and calcium deposition. BMP2-derived peptide induces osteoblast differentiation and ectopic bone regeneration, and improves cranial bone defect repair. Meanwhile, BMP2-derived peptide enhances the cytocompatibility of mesoporous silica nanoparticles, synergistically increases osteogenic activity with Dexamethasone (HY-14648), serving as an important tool for bone defect repair research .
    BMP2-derived peptide
  • HY-W111692

    Biochemical Assay Reagents Others
    Sodium polyphosphate, crystal,+200 mesh, 96% is an inorganic polyphosphate that also serves as a stabilizer, dispersant, chelating agent, and coacervate-forming agent. Sodium polyphosphate provides electrostatic stabilization for mineral and material suspensions, but its dispersing efficacy decreases under acidic pH, high temperature, high calcium concentration, or a combination of these conditions. Sodium polyphosphate can chelate alkaline earth metals, reduce solution pH, and alter the rate of pH decline at a divalent cation/phosphorus molar ratio of 0.18. Sodium polyphosphate forms coacervates with smaller divalent cations and precipitates with larger divalent cations, where the functional requirements of cations depend on polyphosphate concentration, average degree of polymerization, and cation type .
    Sodium polyphosphate, crystal,+200 mesh, 96%
  • HY-132848

    Vimdemer

    Biochemical Assay Reagents Drug Intermediate Cancer
    Polyvinylimidazole (Vimdemer) is a weakly alkaline polyelectrolyte. Polyvinylimidazole can form an anticancer complex with Cadmium chloride. Polyvinylimidazole can be used as a model polyelectrolyte to study the adsorption properties of various minerals .
    Polyvinylimidazole
  • HY-78144

    Drug Derivative Drug Intermediate Inflammation/Immunology
    4-Methylsalicylic acid is a methyl derivative of Salicylic acid (HY-B0167). 4-Methylsalicylic acid derivatives inhibit the activity of alkaline phosphatases such as TNAP and IAP. 4-Methylsalicylic acid derivatives exhibit immunosuppressive activity .
    4-Methylsalicylic acid
  • HY-108531

    RAR/RXR Metabolic Disease
    ER 50891 is a RARα antagonist. ER 50891 can significantly antagonize the inhibitory effect of all-trans retinoic acid (ATRA) on the total cell metabolic activity and proliferation of MC3T3-E1 preosteoblasts. ER 50891 rescues ATRA-inhibited osteocalcin (OCN) expression and extracellular matrix mineralization, and suppresses alkaline phosphatase (ALP) activity synergistically. ER 50891 can be used for the study of osteoporosis related to ATRA-induced inhibition of osteoblastogenesis .
    ER 50891
  • HY-112832

    Phosphatase Infection
    Lumigen APS-5 is a substrate of alkaline phosphatase (ALP). Lumigen APS-5 can be used to assess the activity of alkaline phosphatase (ALP) .
    Lumigen APS-5
  • HY-W008385

    Endogenous Metabolite Metabolic Disease
    H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.
    H-HoArg-OH
  • HY-P2818B
    Alkaline phosphatase, Chicken Intestine
    1 Publications Verification

    Apase, Chicken Intestine

    Endogenous Metabolite Phosphatase Glutathione Peroxidase Bacterial Infection Inflammation/Immunology
    Alkaline Phosphatase (Apase), Chicken Intestine is an alkaline phosphatase from Chicken Intestine, and is one of the most active alkaline phosphatases. Alkaline phosphatase, Chicken Intestine is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase, Chicken Intestine reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase, Chicken Intestine improves survival rate of mice infected with E. coli. Alkaline phosphatase, Chicken Intestine improves TNBS-induced colon inflammation .
    Alkaline phosphatase, Chicken Intestine
  • HY-B2203

    Phosphatase Metabolic Disease
    Monocalcium glycerophosphate is an inhibitor of intestinal alkaline phosphatase F3, and it has anti-cavity properties. Monocalcium glycerophosphate is a source of calcium and phosphorus in total parenteral nutrition solutions, helps prevent the mineralization and development of bones from intravenous nutrition, and maintains the integrity of the intestinal epithelium .
    Monocalcium glycerophosphate
  • HY-13636A

    ICI 182780 (S enantiomer); ZD 9238 (S enantiomer); ZM 182780 (S enantiomer)

    Drug Isomer Estrogen Receptor/ERR p38 MAPK Apoptosis Cancer
    Fulvestrant (ICI 182780; ZD 9238) S enantiomer is the S-enantiomer of Fulvestrant (HY-13636), a potent estrogen receptor inhibitor. Fulvestrant binds to and blocks the estrogen receptor, promotes its degradation, and thereby inhibits receptor dimerization, nucleocytoplasmic shuttling and transcriptional activity. Fulvestrant effectively blocks estrogen signaling, MAPK pathway activation and ER-regulated protein expression. Fulvestrant induces apoptosis, inhibits the proliferation of breast cancer and prolactinoma cells, and reduces the mineralization level, alkaline phosphatase activity and osteocalcin expression of preosteoblasts. Prenatal exposure to Fulvestrant impairs ovarian follicular development and causes ovarian structural damage. Fulvestrant has been widely used in studies related to breast cancer, prolactinoma and other conditions .
    Fulvestrant (S enantiomer)
  • HY-D0812

    Fluorescent Dye Biochemical Assay Reagents Others
    Xylenol Blue is a sulfonephthalein dye. It exhibits observable color changes in response to variations in pH. Xylenol Blue undergoes two distinct color transitions across two specific pH ranges: an acidic range and an alkaline range. In a neutral solution, Xylenol Blue appears yellow (at pH 8); in a strongly acidic medium, its color shifts to red (at pH 2.8); and in an alkaline medium, the yellow hue transitions to blue (at pH 9.6) .
    Xylenol blue
  • HY-D0228

    Azo Violet; Magneson I

    Fluorescent Dye Others
    4-(4-Nitrophenylazo)resorcinol (Azo Violet) is an azo purple dye used experimentally as a pH indicator, showing yellow when the pH value is lower than 11 and purple when the pH value is higher than 13. In slightly alkaline or alkaline environments, it also turns dark blue in the presence of magnesium salts. Azo Violet can also be used to test for the presence of ammonium ions. The color of the ammonium chloride or ammonium hydroxide solution will change depending on the concentration of azo violet used .
    4-(4-Nitrophenylazo)resorcinol
  • HY-W328317

    Azoic diazo No. 4, 90%

    Biochemical Assay Reagents Others
    Fast garnet GBC sulfate salt, 90% is a chromogenic substrate for alkaline phosphatase.
    Fast garnet GBC sulfate salt, 90%
  • HY-130767A

    Biochemical Assay Reagents Cancer
    Naphthol AS-TR Phosphate disodium is a water-soluble dye commonly used as an enzymatic substrate in various biochemical assays to detect alkaline phosphatase activity. Naphthol AS-TR Phosphate disodium has unique chemical properties that allow it to be hydrolyzed by alkaline phosphatase, forming a colored product that can be detected spectrophotometrically. This makes it a useful tool for monitoring enzyme activity in biological samples such as serum or urine.
    Naphthol AS-TR phosphate disodium
  • HY-D1129

    Coumarin 40

    Fluorescent Dye
    Basic yellow 40 is an alkaline dye that can be removed from aqueous solutions in intermittent adsorption systems using tree ferns as biosorbents.
    Basic yellow 40
  • HY-D0492

    Fluorescent Dye
    C.I. Basic blue 41 is an alkaline dye that can be removed from aqueous solutions in intermittent adsorption systems using tree ferns as biosorbents.
    C.I. Basic blue 41
  • HY-D0478

    Fluorescent Dye
    C.I. Basic red 14 is an alkaline dye that can be removed from aqueous solutions in intermittent adsorption systems using tree ferns as biosorbents.
    C.I. Basic red 14
  • HY-W008378

    Biochemical Assay Reagents Others
    5-Methoxy-2-benzimidazolethiol is a benzimidazole. The iodimetric determination of 5-Methoxy-2-benzimidazolethiol in alkaline media is studied .
    5-Methoxy-2-benzimidazolethiol
  • HY-N2247

    Phosphatase Metabolic Disease
    Guaiacin is a arylnaphthalene type lignin isolated from the barks of Machilus thunbergii SIEB. et ZUCC (Lauraceae). Guaiacin significantly increases alkaline phosphatase activity and osteoblast differentiation .
    Guaiacin
  • HY-W661499

    Phosphatase Apoptosis Reactive Oxygen Species (ROS) Caspase Cancer
    Orellanine, a nephrotoxic alkaloid found in Cortinarius orellanus, is an orally active and selective non-competitive inhibitor of alkaline phosphatase. Orellanine chelates iron, generates reactive oxygen species (ROS), induces DNA scission, forms ortho-semiquinone radicals, downregulates antioxidant defenses, and inhibits mitochondrial function. Orellanine induces caspase 8/9-mediated apoptosis. Orellanine inhibits synthesis of proteins, RNA, DNA, and mitochondrial protein synthesis, with metabolic activation required for cell-free protein synthesis inhibition. Orellanine can be used for the research of metastatic clear cell renal cell carcinoma, acute renal failure, chronic renal insufficiency, and kidney damage .
    Orellanine
  • HY-170462

    Biochemical Assay Reagents Others
    CSPD substrate is a chemiluminescent substrate of alkaline phosphatase. CSPD substrate provides the enhanced alkaline phosphatase sensitivity and a more simplified assay .
    CSPD substrate
  • HY-D1491

    Fluorescent Dye Others
    Fast Red Violet LB is a dye for staining tartrate resistant acid phosphatase (TRAP). Fast Red Violet LB can be used for alkaline phosphatase (ALP) activity staining .
    Fast Red Violet LB
  • HY-W008385R

    Reference Standards Endogenous Metabolite Metabolic Disease
    H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.
    H-HoArg-OH (Standard)
  • HY-156752

    Drug Metabolite Others
    Cyclosiversioside F 16,25-diacetate (Compound 6), a glycoside, is an alkaline hydrolysis product of Acetyl Derivative (Compound 2) .
    Cyclosiversioside F 16,25-diacetate
  • HY-W040295

    Phosphatase Others
    Fast Red ITR is a nonlinear optical material . Fast Red ITR can be used in alkaline phosphatase histochemistry .
    Fast Red ITR
  • HY-D1520

    Phosphatase Others
    Naphthol AS-GR phosphate disodium is substrates for acid and alkaline phosphatases. Naphthol AS-GR phosphate disodium has an intense green fluorescence used in histochemical studies .
    Naphthol AS-GR phosphate disodium
  • HY-N15220

    Endogenous Metabolite Phosphatase Cancer
    Dipsacus saponin X (compound 7) is a triterpenoid saponin that stimulates the proliferation of UMR106 cells and increases alkaline phosphatase activity in UMR106 cells (4 μM) .
    Dipsacus saponin X
  • HY-D1676

    Phosphatase Others
    Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum .
    Thymolphthalein monophosphate disodium hydrate
  • HY-W322022

    Biochemical Assay Reagents Others
    Disodium Phenyl phosphate is a substrate for alkaline phosphatase .
    Disodium phenyl phosphate
  • HY-121932

    Phosphatase Others
    Naphthol AS-BR is a substrate for the histochemical demonstration of acid and alkaline phosphatase .
    Naphthol AS-BR
  • HY-W250315

    pectate sodium

    Glycosidase Bacterial Endogenous Metabolite Others
    Polypectate sodium is a major component of cell wall polysaccharides (pectins) and is used as a carbon source and inducer of polygalacturonase. Polypectate sodium can also be used to evaluate alkaline active and alkaline stable pectate lyases from Streptomyces spp. and to study the optimization of polygalacturonase production from Xanthophyllum spp. and reaction conditions .
    Polypectate sodium

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