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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
379 Results for "
anti-miR constructs
" in MedChemExpress (MCE) Product Catalog:
Products (379)
379 Results for "anti-miR constructs" in MCE Product Catalog:
403
403 Publications Verification
Synonyms: Hexadecadrol; Prednisolone F
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist, apoptosis inducer, and common disease inducer in experimental animals, constructing models of muscle atrophy, hypertension, and depression. Dexamethasone can inhibit the production of inflammatory miRNA-155 exosomes in macrophages and significantly reduce the expression of inflammatory factors in neutrophils and monocytes. Dexamethasone also has potential for use in COVID-19 research .
403
403 Publications Verification
Synonyms: Dexamethasone cyclodextrin complex
Dexamethasone (Hexadecadrol) Water Soluble is a water-soluble form of Dexamethasone (HY-14648). Dexamethasone is a glucocorticoid receptor agonist, apoptosis inducer, and a common disease inducer in experimental animals. It can be used to construct models of muscle atrophy, hypertension, and depression. Dexamethasone can inhibit the production of inflammatory miRNA-155 exosomes in macrophages and significantly reduce the expression of inflammatory factors in neutrophils and monocytes. Dexamethasone also has the potential to be used in COVID-19 research .(Sale size is the weight of dexamethasone)
197
197 Cited Publications
Cat. No.: HY-N0565A
CAS No.: 10592-13-9
Target:
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Doxycycline hydrochloride, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hydrochloride shows antibacterial activity and anti-cancer cell proliferation activity. Doxycycline hydrochloride can be used to construct gene expression regulation models .
197
197 Cited Publications
Cat. No.: HY-N0565B
CAS No.: 24390-14-5
Synonyms: Doxycycline hydrochloride hemiethanolate hemihydrate; WC2031
Target:
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Doxycycline hyclate, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor. Doxycycline hyclate shows antibacterial activity and anti-cancer cell proliferation activity. Doxycycline hyclate can be used to construct gene expression regulation models .
14
14 Cited Publications
Synonyms: Thioctic acid; (±)-α-Lipoic acid; DL-α-Lipoic acid
14
14 Cited Publications
Synonyms: Thioctic acid sodium; (±)-α-Lipoic acid sodium; DL-α-Lipoic acid sodium
4
Category:
Target:
4
4 Cited Publications
Target:
Research Areas:
CHAPS is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm-Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS is commonly used in research on the separation and purification of membrane proteins .
4
4 Cited Publications
3
3 Cited Publications
Cat. No.: HY-Y0406E
CAS No.: 10043-52-4
Synonyms: Calcium dichloride anhydrous, for cell culture
3
3 Cited Publications
Synonyms: Diethylenetriaminepentaacetic acid; DTPA
Research Areas:
Pentetic acid (Diethylenetriaminepentaacetic acid) is an orally active compound with biodegradability used to construct magnetic adsorbent, which can simultaneously remove heavy metal and dye from complex wastewater. Pentetic acid can form strong metal complexes, which prevents metal ions from catalysing the decomposition of peroxygen chemicals, especially hydrogen peroxide .
2
2 Cited Publications
Cat. No.: HY-108801
CAS No.: 862111-32-8
Synonyms: VEGF Trap; VEGF-TRAPR1R2; VEGF-trapR1
Target:
Research Areas:
2
2 Cited Publications
Target:
Research Areas:
1
1 Cited Publications
Synonyms: Di(2-hydroxypropyl)nitrosamine; Diisopropanolnitrosamine
Target:
Research Areas:
N-Bis(2-hydroxypropyl)nitrosamine is a tumor model inducing agent and a metabolite of di-n-propylnitrosamine (DPN). N-Bis(2-hydroxypropyl)nitrosamine can be used to construct pancreatic cancer .
1
1 Cited Publications
Cat. No.: HY-K6105
MCE Human Gastric Cancer Organoid Kit contains Gastric Cancer Organoid Basal Medium A, Gastric Cancer Organoid Supplement B (50×), Gastric Cancer Organoid Supplement C (250×). This product can be used to efficiently construct human gastric cancer organoid.
1
1
1 Cited Publications
306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .
1
1 Cited Publications
Target:
Research Areas:
DOTA-NHS-ester is a bifunctional reagent containing a DOTA chelating group and an NHS ester. DOTA-NHS-ester can be conjugated to proteins/antibodies/HSA via primary amino groups for radiolabeling with radiometals, and when combined with 16-amino-1-hexadecanethiol hydrochloride, it enables the construction of self-assembled monolayers on gold surfaces for lectin microarrays. DOTA-NHS-ester can be used to prepare DOTA-HSA-Z (HER2:342) imaging probes, as well as to construct Trop2-targeted radiotherapeutic and diagnostic probes for pancreatic cancer .
1
1 Cited Publications
Cat. No.: HY-128890B
Purity: 95.00%
Target:
Research Areas:
DOTA-NHS-ester TFA is a bifunctional reagent containing a DOTA chelating group and an NHS ester. DOTA-NHS-ester TFA can be conjugated to proteins/antibodies/HSA via primary amino groups for radiolabeling with radiometals, and when combined with 16-amino-1-hexadecanethiol hydrochloride, it enables the construction of self-assembled monolayers on gold surfaces for lectin microarrays. DOTA-NHS-ester TFA can be used to prepare DOTA-HSA-Z (HER2:342) imaging probes, as well as to construct Trop2-targeted radiotherapeutic and diagnostic probes for pancreatic cancer .
1
18:0 mPEG2000 PE (DSPE-mPEG2000) ammonium is a kind of amphiphilic polymer material. 18:0 mPEG2000 PE ammonium combines hydrophobic lipids (18:0 stearic acid chain) with hydrophilic polyethylene glycol (2 kDa) chains to form amphiphilic molecules, which are used to construct stable liposomes/nanoparticles, thereby enhancing drug delivery, prolonging circulation time, and achieving targeted effects through its functional terminal groups (usually biotin or carboxyl groups). 18:0 mPEG2000 PE ammonium can be used for the research of nanoprobes and drug delivery .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
