Copy Link Print Information

Dexamethasone (Water Soluble)

(Synonyms: Dexamethasone cyclodextrin complex)
388 Cited Publications
Customer Review

Based on 388 publication(s) in Google Scholar

Dexamethasone (Hexadecadrol) Water Soluble is a water-soluble form of Dexamethasone (HY-14648). Dexamethasone is a glucocorticoid receptor agonist, apoptosis inducer, and a common disease inducer in experimental animals. It can be used to construct models of muscle atrophy, hypertension, and depression. Dexamethasone can inhibit the production of inflammatory miRNA-155 exosomes in macrophages and significantly reduce the expression of inflammatory factors in neutrophils and monocytes. Dexamethasone also has the potential to be used in COVID-19 research.(Sale size is the weight of dexamethasone)

For research use only. We do not sell to patients.

  • Storage:
    Powder   -20°C, 3 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • Dexamethasone (Water Soluble) Chemical Structure
    Dexamethasone (Water Soluble) Chemical Structure
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
  • Experimental Validation Results for Dexamethasone (Water Soluble)
CAS No.: 50-02-2
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of Dexamethasone (Water Soluble):

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Solvent & Solubility
  • Purity & Documentation
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Dexamethasone (Water Soluble)

More
Customer Validation & Images
RT-PCRIFWBCell Proliferation/Viability Assay
  • WB
  • IF
  • WB
  • RT-PCR
  • IF
  • RT-PCR
  • WB
  • IF
  • WB
  • Cell Proliferation/Viability Assay
  • WB
  • IF
  • RT-PCR
  • IF
  • Cell Proliferation/Viability Assay
  • RT-PCR
  • WB
  • WB
  • IF

All Antibiotic Isoforms

More
Keywords
MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • Dexamethasone (Water Soluble) Chemical Structure
    Dexamethasone (Water Soluble) Chemical Structure
    1/16
  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: Nat Genet. 2024 Apr;56(4):663-674. [Abstract]

    Customer Validation
     Dexamethasone (Dex) (2 h) increases MYC expression in BT549 cells.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: Cell. 2023 Jun 22;186(13):2823-2838.e20. [Abstract]

    Customer Validation
     Whole-mount IF staining for HuC/D, GFAP and pSTAT3 (arrows indicate pSTAT3+ nuclei) (P), and quantification of pSTAT3+ enteric glia cell nuclei normalized to the GFAP+ area (Q) after 7 days of stress or dexamethasone treatment.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: Carbohydr Polym. 2023 Jan 1:299:120179. [Abstract]

    Customer Validation
     Western blotting analysis of Itgb2 levels in Dexamethasone (100 nM; for 1 hour)-treated MODE-K cells.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: Carbohydr Polym. 2023 Jan 1:299:120179. [Abstract]

    Customer Validation
     mRNA levels of Itgb2 in Dexamethasone (100 nM; for 1 hour)-treated MODE-K cells.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: Carbohydr Polym. 2023 Jan 1:299:120179. [Abstract]

    Customer Validation
     Immunofluorescence analysis of Itgb2 in Dexamethasone (100 nM; for 1 hour)-treated MODE-K cells.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: J Cachexia Sarcopenia Muscle. 2022 Aug;13(4):2017-2030. [Abstract]

    Customer Validation
     qRT‐PCR results show that DEX (DEX; 25 μg/g ; once a day; for 10 days)-induced myotube atrophy can increase the expression levels of MuRF1, Atrogin‐1, FoxO3a, SYISL, and miR‐205‐5p, decrease the expression levels of miR‐23a‐3p and miR‐103‐3p, but does not affect the expression level of SYNPO2.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: J Cachexia Sarcopenia Muscle. 2022 Aug;13(4):2017-2030. [Abstract]

    Customer Validation
     Western blotting results show that SYISL overexpression can further promote protein ubiquitination levels in Dexamethasone (DEX; 25 μg/g ; once a day; for 10 days)-induced muscular atrophy. Muscle atrophy is induced by intraperitoneal injection of DEX for 10 days in 3‐month‐old wild‐type and KO mice, respectively.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: J Cachexia Sarcopenia Muscle. 2022 Aug;13(4):2017-2030. [Abstract]

    Customer Validation
     Representative photographs of H&E and Lamin immunofluorescence staining for WT and KO TA muscles. Quantification of five independent experiments shows that knockout of SYISL alleviates muscle weight loss caused by Dexamethasone (DEX; 25 μg/g ; once a day; for 10 days)-induced muscle atrophy.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: Oncogene. 2021 Sep;40(35):5367-5378. [Abstract]

    Customer Validation
     The GR expression of 4T1 cells treated with Dexamethasone (100 nM)/Mifepristone for 48 h.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: Oncogene. 2021 Sep;40(35):5367-5378. [Abstract]

    Customer Validation
     The migration assay of 4T1 cells in different condition. 4T1 cells were pretreated with 100 nM Dexamethasone (Dex) for 48 h and then are used for Transwell.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: Oncogene. 2021 Sep;40(35):5367-5378. [Abstract]

    Customer Validation
     For in situ treatment in the 4T1 tumor model, Dexamethasone (Dex; 3 mg/kg) is performed every three days by gavage twice/day. The expression of Nedd4l, p-Nedd4l, Smad2 and p-Smad2 after SGK1 knockout.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: Oncogene. 2021 Sep;40(35):5367-5378. [Abstract]

    Customer Validation
     4T1 cells are treated with Dexamethasone (Dex; 100 nM)/GSK650394 in vitro for 48 h before inoculation via intravenous injection.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: Br J Pharmacol. 2021 Aug;178(15):2976-2997. [Abstract]

    Customer Validation
     Primary microglial cells incubated with Protopanaxadiol (100 μM), Dexamethasone (100 nM) or Dexamethasone-BSA (10 nM) show remarkable dynorphin A expression. Pretreatment with Dexamethasone-21-mesylate for 0.5 h completely abolished Protopanaxadiol-, Dexamethasone- or Dexamethasone-BSA-stimulated dynorphin A expression.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: Biomaterials. 2020 Feb;232:119730. [Abstract]

    Customer Validation
     Raw264.7 macrophages induced with LPS (1 μg/mL) for 6 h. Then cellular uptake of Cy5-labeled Dexamethasone (Dex)/OxiαCD NPs or Dex/FA-Oxi-αCD NPs is assessed using confocal laser scanning microscopy at various times.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: Biomaterials. 2020 Feb;232:119730. [Abstract]

    Customer Validation
     Raw264.7 cells are treated with various concentrations of blank NPs, free Dexamethasone (Dex), Dex/Oxi-αCD NPs, or Dex/FA-Oxi-αCD NPs for 24 h, the optical density values at 450 nm were measured and the cell viability was determined by CCK-8 assay.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: Biomaterials. 2020 Feb;232:119730. [Abstract]

    Customer Validation
     Raw264.7 cells are treated with various concentrations of blank NPs, free Dexamethasone (Dex), Dex/Oxi-αCD NPs, or Dex/FA-Oxi-αCD NPs for 24 h, mRNA level of iRhom2 in Raw264.7 cells is detected by quantitative real-time PCR. Data are presented by the relative amount of mRNA normalized by GAPDH.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: Biomaterials. 2020 Feb;232:119730. [Abstract]

    Customer Validation
     Western blot analysis of iRhom2, TNF-α, and BAFF expression in Raw264.7 cells treated with various concentrations of blank NPs, free Dexamethasone (Dex), Dex/Oxi-αCD NPs, or Dex/FA-Oxi-αCD NPs for 24 h.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: Biochem Pharmacol. 2020 Oct;180:114145. [Abstract]

    Customer Validation
     After C2C12 myotubes are incubated with Dexamethasone (DEX) and S-Rg3 for 24 h, myotube levels of MuRF1 and atrogin-1 are detected using Western blot analysis.

  • 1/16

    Dexamethasone (Water Soluble) purchased from MedChemExpress. Usage Cited in: Biochem Pharmacol. 2020 Oct;180:114145. [Abstract]

    Customer Validation
     Translocation of FoxO3 after treatment with S-Rg3 in DEX-treated C2C12 myotubes was investigated by immunofluorescence staining.

  • Dexamethasone (Water Soluble)