61 Results for "

antitubercular activity

" in MedChemExpress (MCE) Product Catalog:
Products (61)

61 Results for "antitubercular activity" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-N0804
CAS No.: 14259-46-2
Narirutin, one of the active constituents isolated from citrus fruits, has antioxidant and anti-inflammatory activities. Narirutin is a shikimate kinase inhibitor with anti-tubercular potency .
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1
1 Cited Publications
Cat. No.: HY-N0804R
CAS No.: 14259-46-2
Narirutin (Standard) is the analytical standard of Narirutin. This product is intended for research and analytical applications. Narirutin, one of the active constituents isolated from citrus fruits, has antioxidant and anti-inflammatory activities. Narirutin is a shikimate kinase inhibitor with anti-tubercular potency .
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Cat. No.: HY-N1377
CAS No.: 10176-66-6
Synonyms: Lysionotin
Nevadensin (Lysionotin), a natural flavonoid, is a selective human carboxylesterase 1 (hCE1) inhibitor with an IC50 of 2.64 μM. Nevadensin is more selective for hCE1 than hCE2 (IC50 of 132.8 μM). Nevadensin can induce apoptosis and DNA damage in cancer cells. Nevadensin has a variety of pharmacological effects such as anti-inflammatory, anti-tumour, anti-hypertensive, anti-tubercular, antitussive, antioxidant and anti-microbial activities .
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Cat. No.: HY-160922
CAS No.: 696628-24-7
Target:  

MDM-2/p53 Bacterial

Research Areas:  

Infection Cancer

BAY 249716 stabilizes all three p53 protein variants. BAY 249716 also has antitubercular activity (IC90: <0.10 μg/mL for Tuberculosis) .
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Cat. No.: HY-132910
CAS No.: 2722634-44-6
Target:  

Bacterial

Research Areas:  

Infection

Antitubercular agent-9 shows effective antitubercular activity with a MIC value of 1.03-2.32 μM.
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Cat. No.: HY-124781
CAS No.: 774589-47-8
Purity:  99.05%
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

ML406 is a small molecule probe that shows anti-tubercular activity via M.tuberculosis BioA (DAPA synthase) enzyme inhibition with an IC50 of 30 nM. M.tuberculosis BioA is an enzyme involved in biotin biosynthesis in M.tuberculosis .
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Cat. No.: HY-129943
CAS No.: 20605-40-7
Purity:  99.59%
Target:  

Bacterial

Research Areas:  

Infection

Benzothiohydrazide is an analogue of anti–tubercular agent Isoniazid. Benzothiohydrazide exhibits anti–tubercular activity, with MICs of 132 μM and 264 μM for M. tuberculosis wild type (H37Rv) and clinical mutant strains (IC1 and IC2) .
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Cat. No.: HY-120555
CAS No.: 115070-72-9
Target:  

Bacterial

Research Areas:  

Infection

Texaline is a active product that can be isolated from Amyris species of plants in the Caribbean. Texaline has antitubercular activity .
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Cat. No.: HY-32806
CAS No.: 23056-39-5
2-Chloro-4-methyl-3-nitropyridine is a pyridine derivative that can be used to synthesize 2-methoxypyridine derivatives with antibacterial and antituberculosis activities .
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Cat. No.: HY-139424
CAS No.: 627052-25-9
Purity:  ≥97.0%
Target:  

Bacterial

Research Areas:  

Cancer

SQ609 is a lead compound from a library of dipiperidines. SQ609 inhibits more than 90% of intracellular bacterial growth at 4μg/ml and is toxic to these cells. SQ609 displays a potent antitubercular activity .
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Cat. No.: HY-W012813
CAS No.: 1193-79-9
2-Acetyl-5-methylfuran is a growth inhibitor of Mycobacterium tuberculosis, exhibiting an in vitro anti-tubercular activity with an MIC of 322.58 μM. 2-Acetyl-5-methylfuran demonstrates high safety and can be used for research related to tuberculosis .
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Cat. No.: HY-152138
CAS No.: 2874263-74-6
Target:  

Bacterial Fungal

Research Areas:  

Infection

Antituberculosis agent-8 (Compound 9i) is an antitubercular agent with an MIC of 3.53 μM (1.6 μg/mL) against M. tuberculosis H37Rv. Antituberculosis agent-8 also shows good antifungal activity against A. niger with an MIC of 62.50 μM .
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Cat. No.: HY-126640
CAS No.: 359844-69-2
Target:  

Parasite

Phomoxanthone A is a xanthone dimer, which can be isolated from Phomopsis. Phomoxanthone A exhibits antimalarial and antitubercular activities against Plasmodium falciparum (K1, multidrug-resistant strain, IC50 is 0.11 µg/mL) and Mycobacterium tuberculosis (H37Ra strain, MIC is 0.50 µg/mL). Phomoxanthone A exhibits cytotoxicity in cells KB, BC-1 and Vero, IC50 is 0.99, 0.51 and 1.4 µg/mL, respectively .
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Cat. No.: HY-143232
CAS No.: 414885-92-0
Target:  

Fungal Bacterial

Research Areas:  

Infection Cancer

Antibacterial agent 73 (compound 7a) is a potent antimicrobial agent. Antibacterial agent 73 exhibits very good antitubercular activity (MIC=0.65 µg/mL) against Mtb H37Rv. Antibacterial agent 73 shows good activity against fungal and bacterial. Antibacterial agent 73 also shows cytotoxicity in MCF-7 breast cancer cell lines, with IC50 of 8.20 μM .
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Cat. No.: HY-178802
Target:  

Bacterial

Research Areas:  

Infection

Antitubercular agent-53 (Compound 5b) is an antitubercular agent and antibacterial agent. Antitubercular agent-53 shows antitubercular activity against M. tuberculosis H37RV with an MIC of 4 μg/mL .
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Cat. No.: HY-132928
CAS No.: 2679830-78-3
Target:  

Bacterial

Research Areas:  

Infection

Antitubercular agent-10 shows potent antitubercular activity with a MIC value of 30 nM.
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Cat. No.: HY-162684
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

Antitubercular agent-46 (4B) is an anti-tubercular agent, with a MIC of 7.81 μg/ mL. Antitubercular agent-46 (4B) possesses antioxidant activity .
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Cat. No.: HY-149857
CAS No.: 21696-12-8
Target:  

Bacterial

Research Areas:  

Infection

Antitubercular agent-37 is an antibacterial agent. Antitubercular agent-37 has antimycobacterial activity with an MIC values of 0.16 μg/mL. Antitubercular agent-37 can be used for the research of tuberculosis .
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Cat. No.: HY-147883
CAS No.: 2460651-09-4
Target:  

Bacterial

Research Areas:  

Infection

Antitubercular agent-27 (compound 1) is a potent antitubercular agent with an IC50 value of 3.2 µM, an MIC value of 7.8 µM, an IC90 value of 7.0 µM. Antitubercular agent-27 shows antimycobacterial activity for resistant isolates of Mycobacterium tuberculosis H37Rv. Antitubercular agent-27 shows effective intracellular antimycobacterial activity and low cytotoxicity .
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Cat. No.: HY-147884
CAS No.: 2460651-10-7
Target:  

Bacterial

Research Areas:  

Infection

Antitubercular agent-28 (compound 2) is a potent antitubercular agent with an IC50 value of 1.5 µM, an MIC value of 4.5 µM, an IC90 value of 2.5 µM. Antitubercular agent-28 shows antimycobacterial activity for resistant isolates of Mycobacterium tuberculosis H37Rv. Antitubercular agent-28 shows effective intracellular antimycobacterial activity and low cytotoxicity .
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