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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
710 Results for "
biology
" in MedChemExpress (MCE) Product Catalog:
Products (710)
710 Results for "biology" in MCE Product Catalog:
109
109 Publications Verification
Synonyms: Fluorescein 5-isothiocyanate
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FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .
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46 Cited Publications
Cat. No.: HY-108882B
CAS No.: 9003-98-9
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DNase I is an enzyme that degrades DNA. DNase I is mainly produced by digestive system organs, such as the pancreas and parotid gland. Three types of DNase I are known in mammals: pancreatic type, parotid type, and pancreatico-parotid type. DNase I plays a key role in the cleavage of extracellular DNA, and is critical for limiting inflammatory responses and maintaining homeostasis. DNase I is responsible for digesting extracellular nucleoproteins, which may be essential for preventing autoimmune responses. Decreased DNase I activity may be associated with the onset and progression of systemic lupus erythematosus (SLE). DNase I (RNase & Protease free) is a molecular biology-grade DNase I purified by chromatography to remove RNase and protease .
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16 Cited Publications
Cat. No.: HY-P0239
CAS No.: 92000-76-5
Category:
Natural Products Microorganisms Endogenous metabolite Disease Research Fields Inflammation/Immunology
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16 Cited Publications
Cat. No.: HY-P0239A
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13 Cited Publications
Synonyms: Trisodium citrate dihydrate, for molecular biology
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GSK4112 (SR6452) is a Rev-erbα agonist with an EC50 value of 0.4 μM. GSK4112 can be used as a chemical tool to probe the function of Rev-erbα in transcriptional repression, regulation of circadian biology, and metabolic pathways .
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10 Cited Publications
Cat. No.: HY-B1610N
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9 Cited Publications
Cat. No.: HY-162288
CAS No.: 3036029-72-5
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FAZ-3532 is a G3BP inhibitor (Kd = 0.54 μM) which binds to the NTF2L nsP3 binding pocket in G3BP1. FAZ-3532 disrupts the co-condensation of RNA, G3BP1, and caprin 1. FAZ-3532 inhibits G3BP-driven stress granule formation. FAZ-3532 can be studied as a powerful tool to probe the biology of stress granules and a promising interventions designed to modulate stress granule formation .
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9 Cited Publications
Cat. No.: HY-P99977
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7 Cited Publications
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DCLK1-IN-1 is a selective, oral bioavailability in vivo-compatible chemical probe of the doublecortin like kinase 1 (DCLK1 kinase) domain. DCLK1-IN-1 inhibits DCLK1 and DCLK2 kinases (IC50: DCLK1=9.5/57.2 nM and DCLK2=31/103 nM in binding and kinase assay, respectively). DCLK1-IN-1 shows low toxicity, and can investigate DCLK1 biology and establish its role in cancer, like DCLK1 + pancreatic ductal adenocarcinoma (PDAC) .
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5 Cited Publications
Synonyms: 2-Morpholinoethanesulphonic acid
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5 Cited Publications
Cat. No.: HY-D0858A
CAS No.: 145224-94-8
Synonyms: 2-Morpholinoethanesulphonic acid monohydrate
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5 Cited Publications
Cat. No.: HY-D0858C
CAS No.: 1266615-59-1
Synonyms: 2-Morpholinoethanesulphonic acid hydrate
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5 Cited Publications
Cat. No.: HY-D0858E
CAS No.: 39946-25-3
Synonyms: 2-Morpholinoethanesulphonic acid potassium
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5 Cited Publications
Cat. No.: HY-D0858B
CAS No.: 71119-23-8
Synonyms: 2-Morpholinoethanesulphonic acid sodium salt
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5 Cited Publications
Cat. No.: HY-D0858D
CAS No.: 117961-21-4
Synonyms: 2-Morpholinoethanesulphonic acid hemisodium
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5 Cited Publications
Synonyms: 20α-Hydroxycholesterol
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3
3 Cited Publications
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PROTAC BRD9 Degrader-1 is a PROTAC connected by ligands for Cereblon and BRD9 (IC50=13.5 nM), which can be used as a selective probe useful for the study of BAF complex biology .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
