1431 Results for "

fluorometric imaging plate reader

" in MedChemExpress (MCE) Product Catalog:
Products (1431)

1431 Results for "fluorometric imaging plate reader" in MCE Product Catalog:

87
87 Publications Verification
Cat. No.: HY-42110
CAS No.: 1977-07-7
Target:  

mAChR

Research Areas:  

Neurological Disease

Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist, with blood-brain barrier permeability. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively. [ 11C]-Deschloroclozapine is developed as a promising PET tracer for DREADD imaging .
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87
87 Publications Verification
Cat. No.: HY-42110A
Target:  

mAChR

Research Areas:  

Neurological Disease

Deschloroclozapine dihydrochloride, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist, with blood-brain barrier permeability. Deschloroclozapine dihydrochloride binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively. [ 11C]-Deschloroclozapine dihydrochloride is developed as a promising PET tracer for DREADD imaging .
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48
48 Cited Publications
Cat. No.: HY-D1374
CAS No.: 1144107-82-3
Sulfo-Cy5 carboxylic acid potassium is a Cy5 derivative that can be used for chemical synthesis. Cy5 is a red fluorescent label dye for imaging (Ex/Em=642/670 nm) .
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37
37 Cited Publications
Cat. No.: HY-141511
CAS No.: 874748-20-6
Purity:  97.74%
Coppersensor-1 (CS1) is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu + with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper(I) ions (Cu +) in biological samples, including live cells. Coppersensor-1 can be used for the research of imaging of severe diseases such as cancer, cardiovascular disorders and neurogenerative diseases .
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32
32 Cited Publications
Cat. No.: HY-K2005

High Sensitivity ECL Kit enables low picogram detection of antigen by oxidizing luminol in the presence of HRP and peroxide. This reaction produces a prolonged chemiluminescence which can be visualized on X-ray film or digital imaging systems. The 100 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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32
32 Cited Publications
Cat. No.: HY-128643
CAS No.: 2374782-02-0
Purity:  98.29%
Target:  

FAP

Research Areas:  

Cancer

FAPI-4 is a potent fibroblast activation protein (FAP) inhibitor for the targeting FAP. FAPI-4 can be used in cancer research. 68Ga-FAPI-4 PET/CT is a promising new diagnostic method for imaging various kinds of cancer, with good tumor-to-background contrast ratios .
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22
22 Cited Publications
Cat. No.: HY-K1047

Anti-Fade Mounting Medium (with DAPI) is a mounting reagent designed to retard fluorescence photobleaching and preserve signal intensity during long-term imaging. For immediate observation of samples, please select HY-K1048, a non-solidifying anti-fade mounting medium with DAPI. The 5 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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20
20 Cited Publications
Cat. No.: HY-110251
CAS No.: 1539318-36-9
Purity:  98.11%
DFHBI-1T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells .
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18
18 Cited Publications
Cat. No.: HY-P7114
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RSPO1; R-Spondin Homolog (Xenopus Laevis); R-Spondin 1; R-Spondin Homolog; Roof plate-Specific Spondin-1; CRISTIN3; R-Spondin-1; HRspo1; FLJ40906; RSPO; RSPONDIN
Species:  
Human
Source:  
CHO
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15
15 Cited Publications
Cat. No.: HY-D0040
CAS No.: 1461-15-0
Synonyms: Fluorexon
Calcein is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein cannot directly cross the intact cell membrane of a living cell, unlike Calcein-AM (HY-D0041) which is cell-permeable. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems .
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13
13 Cited Publications
Cat. No.: HY-111330
CAS No.: 359010-69-8
Purity:  99.91%
Synonyms: HPF; 3'-p-(Hydroxyphenyl) fluorescein
Hydroxyphenyl Fluorescein (HPF) is a stable ROS fluorescent probe dye. Hydroxyphenyl Fluorescein has stronger specificity and stability than H2DCFDA (HY-D0940). Hydroxyphenyl Fluorescein can produce strong green fluorescence through hydroxyl radical reaction with intracellular peroxynitroso. Hydroxyphenyl Fluorescein can be applied for fluorescence microscopy, high-throughput imager, luciferase microplate reader or flow cytometry. Ex/Em=490/515 nm .
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11
11 Cited Publications
Cat. No.: HY-115640
CAS No.: 1513848-14-0
Purity:  95.02%
Target:  

TrxR

Research Areas:  

Others

TRFS-green is a highly selective off−on fluorescent probe for imaging selenoprotein thioredoxin reductase (TrxR) in living cells. TRFS-green has the maximum absorbance at around 373 nm. After it is activated by TrxR, the maximum absorbance shifts to around 440 nm .
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8
8 Cited Publications
Cat. No.: HY-119287
CAS No.: 109628-27-5
Purity:  99.50%
TSQ is a cytosolic zinc ion fluorescence probe that is membrane permeable and can be used for intracellular imaging of zinc proteins (λmax ~470 nm). TSQ can combine with Zn 2+ in the presence of Ca 2+ and Mg 2+ to produce blue fluorescence (Ex/Em = 334/495 nm) .
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8
8 Cited Publications
Cat. No.: HY-K2006

Sensitive ECL Kit enables low picogram detection of antigen by oxidizing luminol in the presence of HRP and peroxide. This reaction produces a prolonged chemiluminescence which can be visualized on X-ray film or digital imaging systems. The 100 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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7
7 Cited Publications
Cat. No.: HY-K0322

MCE Cell Ferrous Iron (Fe2+) Assay Kit (Fluorometric) utilizes fluorescence detection technology to analyze the levels of ferrous ions (Fe2+) in cells.

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7
7 Cited Publications
Cat. No.: HY-110250
CAS No.: 1241390-29-3
Purity:  98.85%
DFHBI is a small molecule that resembles the chromophore of green fluorescent protein (GFP). DFHBI can be used for imaging RNA in living cells. . Spinach and DFHBI are essentially nonfluorescent when unbound, whereas the Spinach-DFHBI complex is brightly fluorescent both in vitro and in living cells (Ex/Em = 469/501 nm).
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7
7 Cited Publications
Cat. No.: HY-D1063
CAS No.: 207399-07-3
IR-780 is a near-infrared fluorescent probe for in vivo imaging of tumor cells. IR-780 is transported into tumor cells via OATPs and ABCB10, with uptake dependent on glycolytic activity and plasma membrane potential. IR-780 preferentially accumulates in tumor cell mitochondria, including those of drug-resistant cancer cells, without chemical conjugation. IR-780 generates reactive oxygen species (ROS), induces hyperthermia and apoptosis, inhibits tumor growth and recurrence, and modulates HSP70 expression upon ultrasound or 808 nm laser exposure. IR-780 acts as a sonosensitizer, photodynamic and photothermal agent, and drug delivery carrier, with low acute imaging-dose toxicity and rapid vital organ clearance. IR-780 can be used for the research of cancer, such as breast cancer, lung cancer, and non-small cell lung cancer (NSCLC) .
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5
5 Cited Publications
Cat. No.: HY-B0594
CAS No.: 66108-95-0
Target:  

Autophagy Mitophagy

Research Areas:  

Cancer

Iohexol is a non-ionic, water-soluble contrast agent used as a reference marker for the determination of glomerular filtration rate (GFR) at the level of renal function. Iohexol can be used for contrast in myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging .
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4
4 Cited Publications
Cat. No.: HY-P2377
CAS No.: 219137-85-6
Target:  

Fluorescent Dye

Research Areas:  

Others

Ac-YVAD-AFC is the the fluorometric peptide substrate of caspase-1, with λ excitation of 400 nm and λ emission of 505 nm .
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4
4 Cited Publications
Cat. No.: HY-106244
CAS No.: 177943-88-3
Purity:  99.95%
Synonyms: Oxodotreotide
Research Areas:  

Cancer

DOTATATE is a DOTA-conjugated peptide. DOTATATE can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT) . DOTATATE can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
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