42 Results for "

granule protein

" in MedChemExpress (MCE) Product Catalog:
Products (42)

42 Results for "granule protein" in MCE Product Catalog:

6
6 Publications Verification
Cat. No.: HY-112680A
CAS No.: 2444713-88-4
Purity:  99.49%
Target:  

G-quadruplex

Research Areas:  

Neurological Disease

Carboxy pyridostatin trifluoroacetate salt is a G-quadruplex ligand. Carboxy pyridostatin trifluoroacetate salt has a highly molecular specificity to RNA on DNA G4s and reduces ATF-5 protein. Carboxy pyridostatin trifluoroacetate salt reduces cell proliferation and hinders stress granule (SG) formation .
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6
6 Publications Verification
Cat. No.: HY-112680
CAS No.: 1417638-60-8
Target:  

G-quadruplex

Research Areas:  

Neurological Disease

Carboxypyridostatin is a G-quadruplex ligand. Carboxypyridostatin has a highly molecular specificity to RNA on DNA G4s and reduces ATF-5 protein. Carboxypyridostatin reduces cell proliferation and hinders stress granule (SG) formation .
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3
3 Cited Publications
Cat. No.: HY-162289
CAS No.: 3036029-78-1
Target:  

DNA/RNA Synthesis

Research Areas:  

Neurological Disease Cancer

FAZ-3780 is an inhibitor that binds to the NTF2L domain of G3BP1/2. FAZ-3780 binds to the NTF2L nsP3 of G3BP1 with high affinity, with a Kd of 0.15 μM and a Pep-FRET IC50 of 0.7 μM. FAZ-3780 targets the protein-protein interaction domain of G3BP1/2, and specifically inhibits the co-condensation of G3BP1, caprin 1 and RNA in vitro. FAZ-3780 inhibits stress granule formation and disassembles pre-formed stress granules. FAZ-3780 can be used in studies related to cancer and neurodegenerative diseases .
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2
2 Cited Publications
Cat. No.: HY-W040045
CAS No.: 18466-51-8
Synonyms: Pelargonidin-3-O-glucoside chloride
Callistephin (Pelargonidin 3-O-glucoside) chloride is an anthocyanin. Callistephin chloride regulates the expression of inflammatory (reducing iNOS/TNF-α/COX-2) and apoptosis-related proteins by inhibiting p38 phosphorylation, and enhances the protective effect of Isoflurane (HY-A0134) on microglial cell damage. Callistephin chloride significantly reduces ROS levels, eliminates DPPH free radicals, protects retinal pigment epithelial cells, and inhibits lipid peroxidation. Callistephin chloride can alleviate glutamate excitotoxicity, reduce neuronal apoptosis, and protect cerebellar granule neurons. Callistephin chloride can inhibit the proliferation and metastasis of breast cancer cells by inducing apoptosis .
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1
1 Cited Publications
Cat. No.: HY-131649
CAS No.: 15533-09-2
Purity:  99.32%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Compound C108 is a G3BP2 inhibitor. Compound C108 also targeted stress granule-associated proteins and Gtpase-activating protein (SH3 domain) binding protein 2. Compound C108 potently inhibits esophageal squamous cell carcinoma (ESCC) cell metastasis .
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1
1 Cited Publications
Cat. No.: HY-P76059
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SRGN; Proteoglycan 1, Secretory granule; Prev. PRG1; P.PG; Prev. PRG; Proteoglycan protein Core For Mast Cell Secretory granule; PPG; Secretory granule Proteoglycan Core Peptide; Secretory granule Proteoglycan Core protein; Hematopoetic Proteoglycan Core
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P76058
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SRGN; Proteoglycan 1, Secretory granule; Prev. PRG1; P.PG; Prev. PRG; Proteoglycan protein Core For Mast Cell Secretory granule; PPG; Secretory granule Proteoglycan Core Peptide; Secretory granule Proteoglycan Core protein; Hematopoetic Proteoglycan Core
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P70803
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SELP; Selectin P (granule Membrane protein 140kDa, Antigen CD62); Prev. GRMP; LECAM3; P-Selectin; Selectin P (granule Membrane protein 140kD, Antigen CD62); PADGEM; Leukocyte-Endothelial Cell Adhesion Molecule 2; Platelet Activation Dependent granule-Exte
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P70509
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRTN3; Neutrophil proteinase 4; proteinase 3; Leukocyte proteinase 3; AGP7; Wegener Autoantigen; PR-3; C-ANCA Antigen; P29; NP-4; Myeloblastin; MBN; C-ANCA; PR3; ACPA; Azurophil granule protein 7; MBT; CANCA; Wegener Granulomatosis Autoantigen; NP4; Serin
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-W088068
CAS No.: 68988-92-1
Wright's stain is a composite cell stain that mainly binds to intracellular nucleic acids, proteins and other components through thiazine dyes (such as methylene blue) and eosin. Wright's stain is pH-dependent (optimal pH 6.4-6.7) and achieves cell morphology resolution by differentially staining the cytoplasm and nucleus. Under alkaline conditions, thiazine dyes bind to nucleic acids to form purple, and acidic eosin binds to cytoplasmic proteins to form red, which can form contrasting cell morphological features. Wright's stain can clearly display the fine structures of blood cells and bone marrow cells (such as nuclear chromatin and granules) and quickly evaluate cell morphological abnormalities .
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Cat. No.: HY-W010451
CAS No.: 533-73-3
Synonyms: Hydroxyhydroquinone
1,2,4-Trihydroxybenzene (Hydroxyhydroquinone) is an ER stress inducer that targets proteins such as PKR-like ER kinase PERK to induce cytotoxicity. 1,2,4-Trihydroxybenzene selectively activates eIF2α phosphorylation, activates the PERK-eIF2α signaling pathway and induces stress granule formation. 1,2,4-Trihydroxybenzene subsequently exacerbates oxidative stress and causes DNA double-strand breaks, destroying organelles such as mitochondria and ER, and inducing cell death. 1,2,4-Trihydroxybenzene also has the potential to exhibit anti-tumor effect, increase blood pressure, and relieve spasm .
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Cat. No.: HY-D2933
Target:  

Fluorescent Dye

Research Areas:  

Others

SNAP-505 is a cell-permeable green fluorescent dye (Ex/Em ≈504/532 nm). It binds specifically and covalently to SNAP-tag fusion proteins, and is used for pulse-chase labeling and localization tracking of proteins in living cells. SNAP-505 can be applied to studies related to insulin granule formation, ER-Golgi protein trafficking, and other relevant processes .
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Cat. No.: HY-W040045R
CAS No.: 18466-51-8
Synonyms: Pelargonidin-3-O-glucoside chloride (Standard)
Callistephin (Pelargonidin 3-O-glucoside) chloride (Standard) is the analytical standard of Callistephin chloride (HY-W040045). This product is intended for research and analytical applications. Callistephin chloride is an anthocyanin. Callistephin chloride regulates the expression of inflammatory (reducing iNOS/TNF-α/COX-2) and apoptosis-related proteins by inhibiting p38 phosphorylation, and enhances the protective effect of Isoflurane (HY-A0134) on microglial cell damage. Callistephin chloride significantly reduces ROS levels, eliminates DPPH free radicals, protects retinal pigment epithelial cells, and inhibits lipid peroxidation. Callistephin chloride can alleviate glutamate excitotoxicity, reduce neuronal apoptosis, and protect cerebellar granule neurons. Callistephin chloride can inhibit the proliferation and metastasis of breast cancer cells by inducing apoptosis.
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Cat. No.: HY-P5483
CAS No.: 267890-59-5
Target:  

Bacterial

Research Areas:  

Others

Retro-indolicidin is a biological active peptide. (Reverse peptide of indolicidin (Rev4) is a 13-amino acid residue peptide based on the sequence of indolicidin. Indolicidin, a member of the cathelicidin protein family, is a 13-amino acid residue cationic, antimicrobial peptide-amide isolated from the cytoplasmic granules of bovine neutrophils. The synthetic peptide Rev4 has been shown to possess strong antimicrobial as well as protease inhibitory activities in vitro.)
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Cat. No.: HY-W010451R
CAS No.: 533-73-3
Synonyms: Hydroxyhydroquinone (Standard)
1,2,4-Trihydroxybenzene (Hydroxyhydroquinone) (Standard) is the analytical standard of 1,2,4-Trihydroxybenzene (HY-W010451). This product is intended for research and analytical applications. 1,2,4-Trihydroxybenzene (Hydroxyhydroquinone) is an ER stress inducer that targets proteins such as PKR-like ER kinase PERK to induce cytotoxicity. 1,2,4-Trihydroxybenzene selectively activates eIF2α phosphorylation, activates the PERK-eIF2α signaling pathway and induces stress granule formation. 1,2,4-Trihydroxybenzene subsequently exacerbates oxidative stress and causes DNA double-strand breaks, destroying organelles such as mitochondria and ER, and inducing cell death. 1,2,4-Trihydroxybenzene also has the potential to exhibit anti-tumor effect, increase blood pressure, and relieve spasm .
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Cat. No.: HY-P71037
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ZG16; Zymogen granule protein 16; JCLN; HZG16; JCLN1; ZG16A; Jacalin-Like Lectin Domain Containing; Zymogen granule Membrane protein 16; Secretory Lectin ZG16; Zymogen granule protein 16 Homolog (Rat); Zymogen granule protein 16 Homolog
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P77285
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ZG16; Zymogen granule protein 16; JCLN; HZG16; JCLN1; ZG16A; Jacalin-Like Lectin Domain Containing; Zymogen granule Membrane protein 16; Secretory Lectin ZG16; Zymogen granule protein 16 Homolog (Rat); Zymogen granule protein 16 Homolog
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P71842
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ZG16B; Zymogen granule protein 16B; Zymogen granule protein 16 Homolog B; HRPE773; PRO1567; JCLN2; Pancreatic Adenocarcinoma Up-Regulated Factor; Jacalin-Like Lectin Domain Containing 2; PAUF; Pancreatic Adenocarcinoma Upregulated Factor; Zymogen granule
Species:  
Human
Source:  
P. pastoris
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Cat. No.: HY-P700451
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ZG16B; Zymogen granule protein 16B; Zymogen granule protein 16 Homolog B; HRPE773; PRO1567; JCLN2; Pancreatic Adenocarcinoma Up-Regulated Factor; Jacalin-Like Lectin Domain Containing 2; PAUF; Pancreatic Adenocarcinoma Upregulated Factor; Zymogen granule
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P705436
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TIA1; TIA1 Cytotoxic granule-Associated RNA-Binding protein; TIA1 Cytotoxic granule Associated RNA Binding protein; P40-TIA-1 (Containing P15-TIA-1); T-Cell-Restricted Intracellular Antigen-1; Alternative protein TIA1; TIA-1; P40-TIA-1; Cytotoxic granule
Species:  
Human
Source:  
E. coli
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