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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
46 Results for "
intervention
" in MedChemExpress (MCE) Product Catalog:
Products (46)
46 Results for "intervention" in MCE Product Catalog:
10
10 Publications Verification
Cat. No.: HY-162288
CAS No.: 3036029-72-5
Target:
Research Areas:
FAZ-3532 is a G3BP inhibitor (Kd = 0.54 μM) which binds to the NTF2L nsP3 binding pocket in G3BP1. FAZ-3532 disrupts the co-condensation of RNA, G3BP1, and caprin 1. FAZ-3532 inhibits G3BP-driven stress granule formation. FAZ-3532 can be studied as a powerful tool to probe the biology of stress granules and a promising interventions designed to modulate stress granule formation .
4
4 Cited Publications
Synonyms: 3-Phenylacrylic acid; β-Phenylacrylic acid
Category:
Simple Phenylpropanols Phenylpropanoids Endogenous metabolite Disease Research Fields Cancer
Target:
3
3 Cited Publications
Research Areas:
SKF-83566 is an orally active, blood-brain barrier-permeable D1/D5 dopamine receptor antagonist with a Ki value of approximately 0.4-0.56 nM.
SKF-83566 modulates locomotor behavior and spatial memory by blocking D1 receptors and inhibits glioblastoma progression by targeting the DRD1/c-Myc/UHRF1 pathway.
SKF-83566 acts as an inhibitor of the dopamine transporter (DAT) and adenylyl cyclase 2 (AC2).
SKF-83566 competitively binds to DAT to inhibit dopamine reuptake and non-competitively inhibits AC2 activity, thereby reducing cAMP accumulation.
SKF-83566 is used in research areas such as dopaminergic system mechanisms, learning and memory, targeted intervention for glioblastoma, AC2 pathophysiology, antiparasitic drug screening, and synaptic plasticity (the "gating effect") .
2
2 Cited Publications
Cat. No.: HY-B2165
CAS No.: 81919-14-4
Target:
Research Areas:
Bendazac L-Lysine is one of agents that have been introduced for the management of cataracts, protecting the level of vision in patients, thus delaying the need for surgical intervention.
1
1 Cited Publications
Synonyms: Cycloartenol ferulate; Cycloartenol ferulic acid ester
Cat. No.: HY-172723
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Research Areas:
DSPE-PEG2000-T7 is a PEGylated compound composed of DSPE and peptideT7. T7 (HAIYPRH) specifically binds to TfR. DSPE-PEG2000-T7 can be used to prepare T7-modified liposomes, where liposomes modified with both T7 and DA7R peptides can effectively co-deliver Doxorubicin (HY-15142A) and Vincristine (HY-N0488A) to gliomas. DSPE-PEG2000-T7 can also be used to prepare nanomodulators that mediate the co-delivery of tyrosine hydroxylase mRNA and interferon gene stimulator antagonists for synergistic intervention in Parkinson's disease .
Category:
Umbelliferae/Apiaceae Extract Plant Notopterygium incisum Ting ex H. T. Chang Extract Coumarins Phenols Polyphenols Phenylpropanoids
Target:
Cat. No.: HY-W015399
CAS No.: 1866-39-3
4-Methylcinnamic acid is a cinnamic acid derivative with antifungal activity. 4-Methylcinnamic acid can overcome the tolerance of glutathione reductase mutants to 4-Methoxycinnamic acid (HY-N1387). When 4-Methylcinnamic acid is used in combination with traditional antifungal agents, it can reduce their minimum inhibitory concentrations. 4-Methylcinnamic acid can act as an intervention catalyst to enhance the efficacy of traditional antifungal agents and has application potential in targeting fungal cell wall disruption and controlling drug-resistant fungi .
Cat. No.: HY-N6901
CAS No.: 56857-57-9
Category:
Plant Flavonoids Flavones Metabolic Disease Phenols Polyphenols Other Families Extract Disease Research Fields
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Cat. No.: HY-N0610AS
CAS No.: 91453-04-2
Synonyms: 3-Phenylacrylic acid-d6; β-Phenylacrylic acid-d6
Cat. No.: HY-P11350
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Cat. No.: HY-N0610AS2
CAS No.: 2734410-01-4
Synonyms: 3-Phenylacrylic acid-13C3; β-Phenylacrylic acid-13C3
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Research Areas:
Betamethasone acetate is a glucocorticoid with prenatal application for preventing respiratory distress syndrome (RDS) in premature infants. Betamethasone acetate exhibits dose-dependent effects on somatic and brain development in offspring when administered prenatally to pregnant rats. Betamethasone acetate can be used for the study of antenatal intervention .
Cat. No.: HY-P11350A
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Cat. No.: HY-W015399R
CAS No.: 1866-39-3
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Research Areas:
4-Methylcinnamic acid, a Cinnamic acid analog, can be used as a intervention catalyst for overcoming antifungal tolerance. 4-Methylcinnamic acid can improve the potency of cell wall-disrupting agents .
Cat. No.: HY-N6077
CAS No.: 18251-36-0
Cat. No.: HY-N0610AR
CAS No.: 621-82-9
Synonyms: 3-Phenylacrylic acid (Standard); β-Phenylacrylic acid (Standard)
Cat. No.: HY-N15358
CAS No.: 67889-40-1
Category:
Target:
Cat. No.: HY-110039
CAS No.: 1216920-18-1
BIBX 1382 dihydrochloride is an ErbB kinase inhibitor with significant antiviral activity. BIBX 1382 affects the ability of viruses to enter host cells by inhibiting members of the ErbB kinase family. It can be used to study the interaction mechanism between virus and host and the broad spectrum intervention of highly pathogenic viruses .
Cat. No.: HY-10313
CAS No.: 185836-64-0
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ZD 2486 is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist. ZD 2486 inhibits platelet aggregation by blocking the binding of fibrinogen to the GP IIb/IIIa receptor on platelets. ZD 2486 can be used for the study of conditions related to unwanted platelet aggregation, such as acute coronary syndrome, unstable angina pectoris, acute myocardial infarction, and complications from cardiovascular interventional procedures [1]
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
