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nanoparticle

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GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-134541
    SM-102
    Maximum Cited Publications
    45 Publications Verification

    		 Liposome Infection
    SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
    SM-102
  • HY-W040193
    DSPC
    15+ Cited Publications

    1,2-Distearoyl-sn-glycero-3-PC; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine

    		 Liposome Others
    DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
    DSPC
  • HY-138170
    ALC-0315
    35+ Cited Publications

    		 Liposome SARS-CoV Infection
    ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
    ALC-0315
  • HY-112764
    mPEG2000-DMG
    20+ Cited Publications

    		 Liposome Metabolic Disease
    DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
    mPEG2000-DMG
  • HY-P99974
    Nab-Paclitaxel
    4 Publications Verification

    nanoparticle albumin-bound Paclitaxel; nanoparticle albumin-bound ABI-007

    		 Microtubule/Tubulin Apoptosis Autophagy Cancer
    Nab-Paclitaxel (Nanoparticle albumin-bound Paclitaxel) is an albumin-bound nanoparticle formulation of Paclitaxel (HY-B0015). Nab-Paclitaxel is composed of albumin and the active pharmaceutical ingredient Paclitaxel, in which human albumin is used as an excipient to disperse and stabilize particles and carry the main drug. Nab-Paclitaxel is a solvent-free taxane with higher response rates and improved tolerability. Nab-Paclitaxel displays less toxicity and greater antitumor activity. Nab-Paclitaxel is more readily available for tumor cell uptake in three rhabdomyosarcoma, seven neuroblastoma cell lines, and one ostersarcoma cell line Nab-Paclitaxel can be studied in cancer research for example breast cancer and solid tumors. (The product specifications below only indicate the effective content of Paditaxel, the actual albumin quality depends on the batch; the ratio of each ingredient in this product is Paditaxel: albumin -1:7~1:11) .
    Nab-Paclitaxel
  • HY-W094581
    Gold(III) chloride trihydrate
    1 Publications Verification

    Chloroauric acid trihydrate

    		 Biochemical Assay Reagents Others
    Gold (III) chloride trihydrate is a reducing agent. Gold (III) chromium trihydrate can be used for chemical synthesis of gold nanoparticles (NP) and spirochromene derivatives .
    Gold(III) chloride trihydrate
  • HY-125924
    DSPE-PEG-Amine, MW 2000 ammonium
    1 Publications Verification

    DSPE-PEG-NH2, MW 2000 ammonium; DSPE-PEG(2000) Amine ammonium

    		 Liposome Others
    DSPE-PEG-Amine, MW 2000 (ammonium), an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents .
    DSPE-PEG-Amine, MW 2000 ammonium
  • HY-148033
    Trimethyl chitosan

    N,N,N-Trimethylchitosan

    		 Drug Derivative Others
    Trimethyl chitosan (N,N,N-Trimethylchitosan) is a multifunctional polymer and a derivative of Chitosan (HY-B2144A). Trimethyl chitosan targets the absorption enhancing proteins of tight junctions of intestinal and mucosal epithelial cells, induces tight junction protein rearrangement, and increases intercellular permeability. Trimethyl chitosan can stimulate the activity of promoting transmembrane transport of hydrophilic drugs (such as peptides and proteins) and can be used for drug delivery and synthesis of nanoparticles .
    Trimethyl chitosan
  • HY-W440835
    DSPE-PEG2000-DBCO

    DSPE-PEG2000(2000)-DBCO

    		 Liposome Others
    DSPE-PEG2000-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery . DSPE-PEG2000-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DSPE-PEG2000-DBCO
  • HY-D1540
    Cyanine5.5 amine
    1 Publications Verification

    Cy 5.5 amine; Lumiprobe Cy 5.5 amine

    		 Fluorescent Dye Others
    Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy .
    Cyanine5.5 amine
  • HY-150241
    DOPE-NHS

    		Exosomes Biochemical Assay Reagents Liposome Others
    DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .
    DOPE-NHS
  • HY-151507
    306Oi10
    1 Publications Verification

    		 Liposome Others
    306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .
    306Oi10
  • HY-112760
    18:0 mPEG2000 PE sodium
    1 Publications Verification

    DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium

    		 Liposome Others
    18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .
    18:0 mPEG2000 PE sodium
  • HY-167036
    DMG-PEG2000-Mal

    		Biochemical Assay Reagents Others
    DMG-PEG2000-Mal is a pegylated lipid with a molecular weight of 2000. DMG-PEG-Mal serves as a component of lipid nanoparticles for mRNA delivery .
    DMG-PEG2000-Mal
  • HY-W145518
    Pectin

    		Environmental Pollutants Antibiotic Endogenous Metabolite Bacterial Infection Cancer
    Pectin is a heteropolysaccharide, derived from the cell wall of higher plants. Pectin involves in the formation of nanoparticles as a delivery vehicle of agents. Pectin is also an adsorbent, a broad-spectrum antimicrobial agent that binds to bacteria toxins and other irritants in the intestinal mucosa, relieves irritated mucosa .
    Pectin
  • HY-W105426
    3-(Trimethoxysilyl)propyl methacrylate

    [3-(Methacryloyloxy)propyl]trimethoxysilane

    		 Biochemical Assay Reagents Others
    3-(Trimethoxysilyl)propyl methacrylate is a reactive monomer and silane coupling agent with C=C and O-C=O functional groups, acting as a surface modifier and anti-agglomeration agent. 3-(Trimethoxysilyl)propyl methacrylate can be used to prepare nanoparticles .
    3-(Trimethoxysilyl)propyl methacrylate
  • HY-W011696
    Oleylamine, 80-90%

    cis-1-Amino-9-octadecene, 80-90%

    		 Environmental Pollutants Biochemical Assay Reagents Cancer
    Oleylamine, 80-90% (cis-1-Amino-9-octadecene, 80-90%) is a multifunctional reagent used for metal ion coordination and nanoparticle surface modification, and acts as a solvent, surfactant and reducing agent in the synthesis of metal oxide nanoparticles. Oleylamine, 80-90% regulates nanoparticle morphology, magnetization intensity and water proton relaxation rate via thiol-ene "click" reaction, and enhances the colloidal stability of nanoparticles in organic reagents. Oleylamine, 80-90% is mainly used in research and applications in fields such as nanomaterial synthesis, biomedical imaging (MRI contrast agents, fluorescent probes), cancer cell targeting and drug delivery .
    Oleylamine, 80-90%
  • HY-46759
    Genevant CL1

    		Liposome Infection
    Genevant CL1 is an ionizable lipid (pKa = 6.3) suitable for the preparation of lipid nanoparticles (LNPs) for delivering nucleic acid payloads and intramuscular vaccines. Genevant CL1 is a component of lipid nanoparticle delivery systems for mRNA vaccines .
    Genevant CL1
  • HY-N2362
    DL-Alanine

    DL-2-Aminopropionic acid

    		 Endogenous Metabolite Metabolic Disease
    DL-alanine, an orally active amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .
    DL-Alanine
  • HY-153229
    Firefly luciferase mRNA-LNP
    1 Publications Verification

    		 mRNA Biochemical Assay Reagents Others
    Firefly luciferase mRNA-LNP is a lipid nanoparticle (LNP) containing firefly luciferase mRNA. Firefly luciferase mRNA-LNP exhibits a stable nanostructure, in which LNP plays a key role in effectively protecting and transporting mRNA to cells. Luciferase is a bioluminescent reporter gene for gene regulation and functional studies. Firefly Luciferase mRNA-LNP expresses firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Firefly luciferase mRNA-LNP is studied in research for RNA delivery, cell viability, and translation efficiency .
    Firefly luciferase mRNA-LNP
  • HY-148648
    Lipid 29

    		Liposome Others
    Lipid 29 is an ionizable amino lipid. Lipid 29 can be used to form lipid nanoparticles .
    Lipid 29
  • HY-Y0850O
    Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed)
    3 Publications Verification

    PVA (Mw 31000-50000, 87-89% hydrolyzed); Poly(Ethenol) (Mw 31000-50000, 87-89% hydrolyzed)

    		 Environmental Pollutants Biochemical Assay Reagents Cancer
    Polyvinyl alcohol (PVA; Poly (Ethenol)) (Mw 31000-50000, 87-89% hydrolyzed) is a polymer with emulsifying and stabilizing properties, with a degree of hydrolysis of 87-89%. Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) mainly acts as a stabilizer in the preparation of nanomedicines; it not only maintains the structural integrity of PEGylated PLGA nanoparticles during double emulsion synthesis, but also facilitates the preparation of chitosan/matrine-PLGA nanoparticle aqueous solutions and lipid-polymer nanoparticles. Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) can be widely used in research related to fields such as breast cancer .
    Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed)
  • HY-145794
    ZA3-Ep10

    		Liposome Cancer
    ZA3-Ep10 is a zwitterionic lipid used in lipid nanoparticles formulation for in vivo RNA delivery.
    ZA3-Ep10
  • HY-168399
    PEG(2000)-C-DMG

    		Liposome Cancer
    PEG(2000)-C-DMG is a PEGylated derivative of 1,2-Dimyristoyl-sn-glycerol (HY-128468). PEG(2000)-C-DMG can be used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of siRNA .
    PEG(2000)-C-DMG
  • HY-148049
    TT3

    		Liposome Others
    TT3 is an ionizable lipid-like material and a lipid nanoparticle (LLNs)-based mRNA delivery vector. TT3 exhibits liver and spleen specificity and excellent delivery efficiency .
    TT3
  • HY-P10646
    Muscle homing peptide M12

    		Biochemical Assay Reagents Neurological Disease
    Muscle homing peptide M12 can preferentially bind to surface protein of muscle cells. Muscle homing peptide M12 mediates enhanced cellular uptake of nanoparticles (NPs) in myoblasts in vitro. Muscle homing peptide M12 is covalently conjugated to PLGA-PEG NPs via the N-terminal α-amino groups of peptides using the N-hydroxysuccinimide ester reaction .
    Muscle homing peptide M12
  • HY-136304
    NHS-PEG1-SS-PEG1-NHS

    		PROTAC Linkers Cardiovascular Disease Metabolic Disease Cancer
    NHS-PEG1-SS-PEG1-NHS is a reversible linker for biomacromolecule link with active small molecule. NHS-PEG1-SS-PEG1-NHS can be used in proteins liposomes or nanoparticles .
    NHS-PEG1-SS-PEG1-NHS
  • HY-N16040
    DMG-pSar25

    		Liposome Others
    DMG-pSar25 is a double lipid-tailed polysarcosine lipid with 25 sarcosine moieties, serving as a PEG lipid substitute in lipid nanoparticle formulations for mRNA delivery. DMG-pSar25 supports mRNA delivery in lipid nanoparticle formulations .
    DMG-pSar25
  • HY-N6613
    Polygalacturonic acid

    Galacturonic acid polymer

    		 Others Infection Inflammation/Immunology
    Polygalacturonic acid (Galacturonic acid polymer) is transparent colloid, is a major component of the cell wall. Polygalacturonic acid can be used to prepare silver nanoparticles (AgNPs), as an antioxidant and anti-inflammatory that protect cells from destructive effect of elevated ROS and accelerate wound healing. Polygalacturonic acid nanoparticles also displays anti-bacterial activity .
    Polygalacturonic acid
  • HY-W011060
    Cryptand 2.2.2

    4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane

    		 Biochemical Assay Reagents Others
    Cryptand 2.2.2 (4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane) is a metal ion chelator. Cryptand 2.2.2 forms stable mononuclear, protonated and dinuclear complexes with copper (II) ions; forms protonated complexes with hydrogen ions; and also forms stable complexes with Zn 2+, Co 2+, Ni 2+, Cd 2+, Hg 2+ and Pb 2+ ions. Cryptand 2.2.2 can be used for the preparation of nanoparticles, transition metal compounds, etc.
    Cryptand 2.2.2
  • HY-145793
    FTT5
    2 Publications Verification

    		 Liposome Cardiovascular Disease
    FTT5 is an ionizable lipid that can be used to prepare lipid nanoparticles for efficient delivery of long-chain mRNA in vivo .
    FTT5
  • HY-159726
    C10-200

    		Liposome Others
    C10-200 is an ionizable cationic lipid that can be used to generate lipid nanoparticles (LNPs). C10-200 is used in the study of mRNA delivery .
    C10-200
  • HY-155902
    Mal-PEG5000-OH

    Maleimide-PEG5000-Hydroxy

    		 Biochemical Assay Reagents Others
    Mal-PEG5000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
    Mal-PEG5000-OH
  • HY-W243303O
    Poly(acrylic acid) (MW 1250000) (viscous liquid)

    		Environmental Pollutants Biochemical Assay Reagents Cancer
    Poly(acrylic acid) (Mv 1250000) (viscous liquid) is a polyacrylic acid with a molecular weight of 1250000 (an anionic polymer), which can be used as a corrosion inhibitor and surface stabilizer. Poly(acrylic acid) can be used to construct an anionic nanogel to encapsulate positively charged enzymes and to modify MoS₂ nanoparticles to build a transdermal drug delivery system .
    Poly(acrylic acid) (MW 1250000) (viscous liquid)
  • HY-139306
    BAMEA-O16B

    		Liposome Inflammation/Immunology
    BAMEAO16B is a lipid nanoparticle. BAMEAO16B integrated with disulfide bonds, can efficiently deliver Cas9 mRNA and sgRNA into cells while releasing RNA in response to the reductive intracellular environment for genome editing. BAMEAO16B can be used for the research of gene editing .
    BAMEA-O16B
  • HY-159717
    Lipid 331

    		Liposome Others
    Lipid 331 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid 331 is a carrier for both siRNA and mRNA .
    Lipid 331
  • HY-160439
    Ionizable lipid-2

    		Liposome Others
    Ionizable lipid-2 (Compound 1) is an ionizable lipid that can be used for the preparation of lipid nanoparticles and vaccine research .
    Ionizable lipid-2
  • HY-P5021
    Cyclo(Arg-Gly-Asp-(D-Phe)-Glu)

    c(RGDfE)

    		 Integrin Cancer
    Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) c(RGDfE) is a cyclic RGD peptide targeting integrin αvβ3. Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) is commonly used for modifying drug loaded nanoparticles. Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) is often used in cancer research, such as pancreatic cancer .
    Cyclo(Arg-Gly-Asp-(D-Phe)-Glu)
  • HY-160552
    244cis

    		Liposome Others
    244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels .
    244cis
  • HY-W250183B
    Polyoxyethylene (20) stearyl ether

    Polyethylene glycol octadecyl ether (n～20)

    		 Environmental Pollutants Liposome Others
    Polyoxyethylene (20) stearyl ether (Polyethylene glycol octadecyl ether (n～20)) is a PEGylated lipid surfactant. Polyoxyethylene (20) stearyl ether is used in studies on the formation and stabilization of lipid nanoparticles .
    Polyoxyethylene (20) stearyl ether
  • HY-159716
    Lipid 50

    		Liposome Others
    Lipid 50 (compound 50) is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid 50 is a carrier for both siRNA and mRNA .
    Lipid 50
  • HY-157252
    CL4F8-6

    		Liposome Cancer
    CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics .
    CL4F8-6
  • HY-159854
    C14-O2

    		Liposome Cancer
    C14-O2 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
    C14-O2
  • HY-P5533
    CRT

    		Biochemical Assay Reagents Cancer
    CRT, an iron peptide mimic, can bind to apo-transferrin (apo-Tf). CRT can be used to modify nanoparticles, and enhances drug delivery efficiency .
    CRT
  • HY-155902A
    Mal-PEG2000-OH

    Maleimide-PEG2000-Hydroxy

    		 Biochemical Assay Reagents Others
    Mal-PEG2000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
    Mal-PEG2000-OH
  • HY-164071
    Carboxymethyl Dextran

    CM-Dextran

    		 Drug Derivative Others
    Carboxymethyl Dextran (CM-Dextran) is a dextran derivative and a biocompatible coating for superparamagnetic iron oxide nanoparticles. When coated on the surface of superparamagnetic nanoparticles, Carboxymethyl Dextran forms stable particles across all pH values and NaCl concentrations. Carboxymethyl Dextran can be used to prepare materials for magnetic resonance molecular imaging .
    Carboxymethyl Dextran
  • HY-D2004
    ATTO 488 streptavidin

    		Fluorescent Dye Inflammation/Immunology
    ATTO 488 streptavidin is a fluorescent reagent that specifically targets and binds to biotin (biotin), formed by the conjugation of ATTO 488 with streptavidin (HY-P3152). ATTO 488 streptavidin enables visualization of the activity of streptavidin immobilized on the surface of polymeric nanoparticles, or acts as a fluorescent probe to detect the selective binding and internalization process of anti-HB-EGF/NA with cells expressing HB-EGF (with no such effect on cells that do not express this receptor). ATTO 488 streptavidin effectively verifies the function of streptavidin conjugated to the surface of nanoparticles and is suitable for research related to atherosclerotic cardiovascular diseases .
    ATTO 488 streptavidin
  • HY-W1048555A
    Mal-PEG2000-SCM

    		Biochemical Assay Reagents Others
    Mal-PEG2000-SCM is a heterobifunctional PEG crosslinker bearing maleimide and succinimidyl carboxymethyl ester functional groups. MMal-PEG2000-SCM conjugates the F3 peptide to nanoparticles: the SCM group reacts with amino groups on the nanoparticle surface to form amide groups, while the MAL group reacts with thiol groups of the F3 peptide to form carbon-sulfur bonds. Mal-PEG-SCM enables unidirectional addition of linkers, ensuring that appropriate functional groups are available for RGD incorporation. Mal-PEG2000-SCM can be used in the development of nanoparticles targeting specific tumor cells .
    Mal-PEG2000-SCM
  • HY-153231A
    eGFP mRNA-LNP (500 ng/μL)

    		Fluorescent Dye Liposome Others
    eGFP mRNA-LNP (500 ng/μL) is a lipid nanoparticle (LNP) containing eGFP mRNA. eGFP mRNA-LNP carries Enhanced Green Fluorescent Protein (eGFP), which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry (excitation wavelength = 488 nm; emission wavelength = 535/40 bandpass). eGFP mRNA-LNP can be used for RNA delivery, translation efficiency and cell viability .
    eGFP mRNA-LNP (500 ng/μL)
  • HY-P10679
    GPLGLAGGWGERDGS

    		MMP Cancer
    GPLGLAGGWGERDGS is a peptide with MMP enzyme responsiveness and tumor targeting function, which can be used to monitor enzyme-guided nanoparticle assembly in tumors .
    GPLGLAGGWGERDGS

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