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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
phase separation
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "phase separation" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-W134422
CAS No.: 9036-19-5
Synonyms: Polyoxyethylene octylphenol ether
1
1 Cited Publications
Cat. No.: HY-126437A
CAS No.: 26124-78-7
Cat. No.: HY-W099535
CAS No.: 2044-56-6
Cat. No.: HY-162543
CAS No.: 384833-00-5
Synonyms: 18:1 Lissamine rhodamine PE
Target:
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18:1 Liss Rhod (18:1 Lissamine rhodamine) PE is a fluorescent phospholipid and fluorescent probe.18:1 Liss Rhod PE admixes into phospholipid inks for large-scale monitoring of dip-pen nanolithography-generated lithographic structures via fluorescence microscopy.18:1 Liss Rhod PE undergoes phase separation or self-quenching under certain conditions in thin lipid membrane stacks .
Cat. No.: HY-174801
CAS No.: 3117797-30-2
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XL-3156 is a cGAS inhibitor. XL-3156 occupies both allosteric and orthosteric sites simultaneously, and inhibits the interaction and phase separation between cGAS and DNA by stabilizing the closed conformation of the activation loop. XL-3156 can be used in the research of diseases such as autoimmune diseases and inflammation .
Cat. No.: HY-W133920
CAS No.: 25322-69-4
Synonyms: PPG 2000
Cat. No.: HY-P5997
CAS No.: 2104728-28-9
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Cat. No.: HY-W067358
CAS No.: 109-08-0
Cat. No.: HY-174802
CAS No.: 3117797-77-7
Target:
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XL-3158 is a selective and cross-species Cyclic GMP-AMP synthase (cGAS) inhibitor (IC50: 11.1 μM for human cGAS, 2.19 μM for mouse cGAS). XL-3158 simultaneously occupy allosteric and orthosteric sites, stabilizing the activation loop in a closed, inactive conformation and thereby attenuating the cGAS-DNA interactions. XL-3158 inhibits cGAS by targeting phase separation. XL-3158 efficiently penetrates cells by inhibiting aggregate formation, effectively reducing the local concentration of cGAS within cells. XL-3158 can be used for the study of cGAS-dependent inflammatory diseases.
Cat. No.: HY-W040184
CAS No.: 80526-82-5
Synonyms: TMAHS
Cat. No.: HY-159925
CAS No.: 2646682-38-2
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QKY-613 is a prodrug that enhances immune surveillance by targeting nucleic acid modification pathways. QKY-613 promotes the selective incorporation of 6mdA (N6-methyldeoxyadenosine) into viral DNA, enhancing the phase separation potential of DNA, thereby increasing the activation of cGAS and strengthening host immune surveillance. In virus-infected mouse models, QKY-613 significantly reduced mortality in aged mice. QKY-613 holds promise for research on nucleic acid modification-based immune surveillance mechanisms .
Cat. No.: HY-W017224
CAS No.: 2386-54-1
Synonyms: Sodium 1-butanesulfonate
Cat. No.: HY-176048
CAS No.: 152813-63-3
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ChEMBL22003 is a potential phase separation modulator of ARV7 that can bind to the ARV7 binding sites. ChEMBL22003 has potential for use in the research of prostate cancer .
Cat. No.: HY-116664
CAS No.: 1431362-93-4
DPQZ is an anti-tubulin agent that inhibits cell separation and induces cell cycle arrest at the G2/M phase. In addition, DPQZ induces caspase-dependent apoptosis of HSC-3 cells by inhibiting Ras/Raf and activating MAP kinase. DPQZ can be used in the study of oral cancer .
Cat. No.: HY-150286A
CAS No.: 2715974-36-8
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(R)-SM875 is a degrader targeting the intermediate folding form of prion protein (PrP). (R)-SM875 significantly reduces the PrP level, with an IC50 of 3 μM. (R)-SM875 can be used for the study of prion diseases .
Cat. No.: HY-W008952
CAS No.: 81741-28-8
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Tributyltetradecyl phosphonium chloride is a quaternary phosphonium salt cation. Tributyltetradecyl phosphonium chloride can form an acidic aqueous biphasic system with acid and water, exhibits temperature-induced phase separation behavior with a lower critical solution temperature, enables the partitioning of Co 2+, Fe 3+, Pt 4+ and Ni 2+ between the two phases, and also promotes the separation of Co 2+ and Ni 2+ .
Cat. No.: HY-W673649
CAS No.: 108392-10-5
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N-Oleyl-sphingomyelin is a bilayer property lipid modulator with affinity for cholesterol bilayers. N-Oleyl-sphingomyelin reduces the amount of cholesterol required for liquid-ordered phase formation and enhances the cholesterol tolerance of membrane structures. N-Oleyl-sphingomyelin can be used in studies related to membrane lipid phase separation and lipid raft structures .
Cat. No.: HY-P11504
CAS No.: 3109821-26-0
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
