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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
61 Results for "
phosphorus
" in MedChemExpress (MCE) Product Catalog:
Products (61)
61 Results for "phosphorus" in MCE Product Catalog:
6
Target:
Environmental Pollutants Apoptosis FXR Calcium Channel Toll-like Receptor (TLR) SOD Reactive Oxygen Species (ROS) DNA/RNA Synthesis Interleukin Related NF-κB TNF Receptor
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Tris(2-chloroethyl) phosphate (TCEP) is a widely used organic phosphorus flame retardant, mainly used as a plasticizer. Tris(2-chloroethyl) phosphate has orally active hepatotoxicity, inducing an increase in reactive oxygen species (ROS) and calcium ions (Ca²⁺) influx, a decrease in mitochondrial membrane potential (△Ψm), and causing DNA damage and cell apoptosis. Tris(2-chloroethyl) phosphate directly binds to FXR, inducing obesity and the formation of fatty liver in mice. Chloroethyl) phosphate activates the TLR4/NF-κB pathway, triggering liver inflammation .
3
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Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .
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Pralidoxime chloride is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime chloride reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime chloride is an antidote for organophosphate poisoning .
1
1 Cited Publications
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Sevelamer hydrochloride is an orally active polymeric phosphate binder and bile acid sequestrant. Sevelamer hydrochloride binds dietary phosphate in the gastrointestinal tract, reducing phosphate absorption and serum phosphorus levels, and reduces urinary phosphate excretion. Sevelamer hydrochloride binds polyanion bile acids, increases bile acid faecal excretion, and reduces total cholesterol and LDL cholesterol levels. Sevelamer hydrochloride can be used for the research of hyperphosphataemia, hyperparathyroidism, chronic renal failure, kidney disease, and type 2 diabetes .
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1
1 Cited Publications
Cat. No.: HY-13995B
CAS No.: 845273-93-0
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Sevelamer carbonate is an orally active polymeric phosphate binder and bile acid sequestrant. Sevelamer carbonate binds dietary phosphate in the gastrointestinal tract, reducing phosphate absorption and serum phosphorus levels, and reduces urinary phosphate excretion. Sevelamer carbonate binds polyanion bile acids, increases bile acid faecal excretion, and reduces total cholesterol and LDL cholesterol levels. Sevelamer carbonate can be used for the research of hyperphosphataemia, hyperparathyroidism, chronic renal failure, kidney disease, and type 2 diabetes .
1
1 Cited Publications
Cat. No.: HY-N0814A
CAS No.: 123408-98-0
Synonyms: Inositol hexaphosphate dodecasodium hydrate; SNF472 dodecasodium hydrate
1
1 Cited Publications
Synonyms: TPPO; Triphenyl phosphorus oxide; Triphenylphosphine monoxide
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Triphenylphosphine oxide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Synonyms: CLTX-305; JTT-305; MK-5442
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Encaleret (CLTX-305) is an orally active antagonist of the calcium-sensing receptor (CaSR), with an IC50 of 12 nM. Encaleret exerts its effect by inhibiting the excessive activity of functional gain-of-function CaSR variants, and can restore blood calcium levels, promote the secretion of parathyroid hormone, improve magnesium and phosphorus metabolism, and increase urinary calcium excretion. Encaleret can be used in the research of diseases such as osteoporosis and autosomal dominant hypocalcemia type 1 .
Cat. No.: HY-107929
CAS No.: 37286-92-3
Synonyms: Poly(styrenesulfonic acid) calcium salt
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Calcium polystyrene sulfonate (Poly(styrenesulfonic acid) calcium salt) is an orally active potassium-lowering agent. Calcium polystyrene sulfonate binds potassium in the distal colon in exchange for Ca 2+. Calcium polystyrene sulfonate can be used for the research of hyperkalemia in chronic kidney disease .
Synonyms: DPPP
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Pralidoxime iodide is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime iodide reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime iodide is an antidote for organophosphate poisoning .
Cat. No.: HY-W111692
CAS No.: 68915-31-1
Cat. No.: HY-W019872
CAS No.: 7722-76-1
Cat. No.: HY-W088069
CAS No.: 16788-57-1
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Dipotassium hydrogen phosphate trihydrate, which is commonly used as a buffer and source of phosphorus and potassium in various applications, such as fertilizers, food processing, and pharmaceuticals, in biochemistry and molecular biology, Dipotassium hydrogen phosphate trihydrate is used in the preparation of cell culture media And reagent buffer system, in addition, it has been used in analytical chemistry as a reagent for the determination of calcium and magnesium ions in water samples.
Cat. No.: HY-P4821
CAS No.: 83139-29-1
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Phosphoenolpyruvate carboxylase, Microorganism (PEPC) is a carbon dioxide fixing enzyme that in an irreversible manner and in the presence of Mg 2+, converts phosphoenolpyruvate and bicarbonate into oxaloacetate and inorganic phosphorus. Phosphoenolpyruvate carboxylase catalyses the primary assimilation of CO(2) in Crassulacean acid metabolism plants. Phosphoenolpyruvate carboxylase plays a major role in setting the day-night pattern of metabolism in plants .
Cat. No.: HY-W250124
CAS No.: 63231-63-0
Synonyms: RNA (yeast)
Cat. No.: HY-B2203
CAS No.: 27214-00-2
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Monocalcium glycerophosphate is an inhibitor of intestinal alkaline phosphatase F3, and it has anti-cavity properties. Monocalcium glycerophosphate is a source of calcium and phosphorus in total parenteral nutrition solutions, helps prevent the mineralization and development of bones from intravenous nutrition, and maintains the integrity of the intestinal epithelium .
Cat. No.: HY-B0819
CAS No.: 14816-18-3
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Phoxim is an organic phosphorus pesticide and widely applies worldwide for agricultural purposes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
