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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
193 Results for "
protein kinase C (PKC)
" in MedChemExpress (MCE) Product Catalog:
Products (193)
193 Results for "protein kinase C (PKC)" in MCE Product Catalog:
860
860 Publications Verification
Cat. No.: HY-18739
CAS No.: 16561-29-8
Synonyms: PMA; TPA; Phorbol myristate acetate
235
235 Cited Publications
Synonyms: Antibiotic AM-2282; STS; AM-2282
138
Category:
Infection Microorganisms Antibiotics Disease Research Anticancer Disease Research Fields Other Antibiotics
Target:
138
138 Cited Publications
Synonyms: SQ23377 calcium
Category:
Infection Microorganisms Antibiotics Disease Research Anticancer Disease Research Fields Other Antibiotics
Target:
49
49 Cited Publications
Synonyms: Mitozantrone; NSC 301739
Category:
Target:
49
49 Cited Publications
Synonyms: Mitozantrone dihydrochloride; NSC 301739 dihydrochloride
39
39 Cited Publications
Synonyms: PKC412; CGP 41251
Midostaurin (PKC412; CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM . Midostaurin also upregulates endothelial nitric oxide synthase (eNOS) gene expression. Midostaurin shows powerful anticancer effects .
15
15 Cited Publications
Target:
Research Areas:
Go6976 is a Protein Kinase C (PKC) inhibitor, with an IC50 of 20 nM.
8
6
6 Cited Publications
Synonyms: Erythrosphingosine; erythro-C18-Sphingosine; trans-4-Sphingenine
Target:
4
4 Cited Publications
Synonyms: LXS196; IDE196
Darovasertib (LXS196) is a potent, selective and orally active protein kinase C (PKC) inhibitor, with IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively. Darovasertib has the potential for uveal melanoma research .
4
4 Cited Publications
Synonyms: (RS)-3,5-DHPG
Target:
Research Areas:
DHPG is the agonist for mGluR 1/5 (EC50 for mGluR 1 is 60 nM) that activates the phospholipase C (PLC) pathway, and leads ultimately to the activation of protein kinase C (PKC) .
4
3
3 Cited Publications
Synonyms: NSC 65346; BA-90912
Target:
3
2
2 Cited Publications
Research Areas:
TPPB is a cell-permeable benzolactam-derived protein kinase C (PKC) activator with a Ki of 11.9 nM.
2
Target:
Research Areas:
2
2 Cited Publications
Research Areas:
PKC-iota inhibitor 1 is a protein kinase C-iota (PKC-ι) inhibitor with an IC50 value of 0.34 μM. PKC-iota inhibitor 1 can be used for the study of cancer .
2
Target:
Research Areas:
2
2 Cited Publications
R59949 is a pan diacylglycerol kinase (DGK) inhibitor with an IC50 of 300 nM. R59949 strongly inhibits the activity of type I DGK α and γ and moderately attenuates the activity of type II DGK θ and κ. R59949 activates protein kinase C (PKC) by enhancing the levels of the endogenous ligand diacyl glycerol .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
