70 Results for "

pyrrolizidine alkaloid

" in MedChemExpress (MCE) Product Catalog:
Products (70)

70 Results for "pyrrolizidine alkaloid" in MCE Product Catalog:

48
48 Publications Verification
Cat. No.: HY-N0750
CAS No.: 315-22-0
Synonyms: Crotaline
Monocrotaline is an 11-membered macrocyclic pyrrolizidine alkaloid. Monocrotaline inhibits OCT-1 and OCT-2 with IC50s of 36.8 µM and 1.8 mM, respectively. Monocrotaline has antitumor activity and is cytotoxic to hepatocellular carcinoma cells. Monocrotaline is used to induce a model of pulmonary hypertension in rodents. [2][6][8].
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2 Cited Publications
Cat. No.: HY-N6638
CAS No.: 480-54-6
Retrorsine is a naturally occurring toxic pyrrolizidine alkaloid. Retrorsine can bind with DNA and inhibits the proliferative capacity of hepatocytes. Retrorsine can be used for the research of hepatocellular injury .
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1
1 Cited Publications
Cat. No.: HY-113845
CAS No.: 10285-06-0
Purity:  ≥99.0%
(+)-Intermedine, a pyrrolizidine alkaloid (PA), exhibits significant cytotoxicity in neural progenitor cells (NPCs) .
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Cat. No.: HY-N2560
CAS No.: 130-01-8
Synonyms: Senecionan-11,16-dione, 12-hydroxy-; Aureine; Senecionin
Senecionine (Senecionan-11,16-dione, 12-hydroxy-) is a pyrrolizidine alkaloid could be isolated from Senecio vulgaris. Senecionine decreases the activities of glutathione S-transferase, aminopyrine demethylase and arylhydrocarbon hydroxylase (AHH) .
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Cat. No.: HY-133591
CAS No.: 72755-25-0
Purity:  95.39%
Target:  

Bacterial

Research Areas:  

Infection

Senecivernine, a pyrrolizidine alkaloid isolated from Senecio species, exhibits a weakly mutagenic activity .
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Cat. No.: HY-122509
CAS No.: 2318-18-5
Purity:  98.79%
Synonyms: Senkirkine; Renardin
Senkirkin is a pyrrolizidine alkaloid derived from Tussilago farfara. Senkirkin induces chromosomal damage in lymphocytes and is metabolized by CYP3A4 .
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Cat. No.: HY-N6637S
Senecionine N-oxide-d3 is the deuterium labeled Senecionine N-oxide. Senecionine n-oxide is the primary product of pyrrolizidine alkaloid biosynthesis in root cultures of Senecio vulgaris. Senecionine N-oxide has anti-cancer activity .
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Cat. No.: HY-N8623
CAS No.: 14140-18-2
Trachelanthamine is a pyrrolizidine alkaloid isolated from the plant .
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Cat. No.: HY-126128
CAS No.: 303-33-3
Research Areas:  

Cancer

Heliotrine is a monoester pyrrolizidine alkaloid and is used for obtaining models of hepatitis and cirrhosis of the liver .
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Cat. No.: HY-105529
CAS No.: 41708-76-3
Synonyms: (+)-Indicine N-oxide; NSC 132319
Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, is an antitumor agent for pediatric cancer and solid tumors research .
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Cat. No.: HY-124058
CAS No.: 6870-67-3
Jacobine?is a pyrrolizidine alkaloid (PA) from Senecio jacobaea . Jacobine is active against second instar larvae of thrips .
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Cat. No.: HY-N6931
CAS No.: 15503-87-4
Usaramine is a pyrrolizidine alkaloid that can be isolated from seeds of Crolatalaria pallida. Usaramine selective Usaramine demonstrates antibiofilm activity against Staphylococcus epidermidis. Usaramine can be used for the research of bacterial infections .
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Cat. No.: HY-N8419
CAS No.: 480-85-3
Synonyms: (+)-Retronecine
Retronecine ((+)-Retronecine) is a pyrrolizidine alkaloid found in a variety of plants. Retronecine is the most common central core for other pyrrolizidine alkaloids .
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Cat. No.: HY-122488
CAS No.: 6029-84-1
Synonyms: Heliotridine trachelanthate
Rinderine (Heliotridine trachelanthate) is a pyrrolizidine alkaloid .
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Cat. No.: HY-N16470
CAS No.: 633-16-9
Echiumine, a pyrrolizidine alkaloid, is a major dehydropyrrolizidine metabolite of Echium plantagineum. Echiumine has significant hepatotoxic activity and can persist intact from honey through to the resulting mead .
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Cat. No.: HY-133590
CAS No.: 6209-65-0
Research Areas:  

Cancer

Heliotrine N-oxide is the corresponding PA (pyrrolizidine alkaloid) N-oxide of Heliotrine (HY-126128). Heliotrine N-oxide leads to the formation of pyrrolic DNA adducts and potential initiation of PA-induced liver tumors in vivo .
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Cat. No.: HY-N1282R
CAS No.: 480-81-9
Seneciphylline (Standard) is the analytical standard of Seneciphylline. This product is intended for research and analytical applications. Seneciphylline is a toxic pyrrolizidine alkaloid in Gynura japonica . Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities .
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Cat. No.: HY-116832
CAS No.: 15503-86-3
Retrorsine N-oxide, an N-oxide of pyrrolizidine alkaloid, is a carcinogen. Retrorsine N-oxide-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides .
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Cat. No.: HY-N1283
CAS No.: 90341-45-0
Seneciphyllinine, a pyrrolizidine alkaloid, is isolated from the roots of Gynura japonica. Pyrrolizidine alkaloids are highly hepatotoxic natural chemicals that produce irreversible chronic and acute hepatotoxic effects on human beings .
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