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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
546 Results for "
quadrupole coupling parameters
" in MedChemExpress (MCE) Product Catalog:
Products (546)
546 Results for "quadrupole coupling parameters" in MCE Product Catalog:
53
53 Publications Verification
Cat. No.: HY-B0445A
CAS No.: 20111-18-6
Synonyms: β-DPN sodium; β-NAD sodium; β-Nicotinamide Adenine Dinucleotide sodium
8
8 Cited Publications
Synonyms: Maleimidocaproyl monomethylauristatin F
연구분야:
McMMAF (Maleimidocaproyl monomethylauristatin F) is a drug-linker conjugate for ADCs, formed by coupling the potent microtubule inhibitor Monomethyl auristatin F (MMAF) (HY-15579) with a maleimidocaproyl (mc) linker. McMMAF can be conjugated with anti-BCMA antibodies to form J6M0-mcMMAF, promoting apoptosis and inhibiting tumor growth .
7
7 Cited Publications
Synonyms: 2-(Phosphonomethyl)pentanedioic acid
Target:
연구분야:
2-PMPA (2-(Phosphonomethyl)pentanedioic acid) is a glutamate carboxypeptidase II (GCPII) inhibitor with an IC50 of 0.0003 μM. 2-PMPA shows low blood-brain barrier penetration. 2-PMPA sodium blocks the hydrolysis of NAAG, regulates glutamate levels in the brain and neurovascular coupling. 2-PMPA is applicable to the research of neurological diseases .
7
7 Cited Publications
Cat. No.: HY-100788C
CAS No.: 373645-42-2
Synonyms: 2-(Phosphonomethyl)pentanedioic acid sodium
Target:
연구분야:
2-PMPA (2-(Phosphonomethyl)pentanedioic acid) sodium is a glutamate carboxypeptidase II (GCPII) inhibitor with an IC50 of 0.0003 μM. 2-PMPA sodium shows low blood-brain barrier penetration. 2-PMPA sodium blocks the hydrolysis of NAAG, regulates glutamate levels in the brain and neurovascular coupling. 2-PMPA sodium is applicable to the research of neurological diseases .
7
7 Cited Publications
Cat. No.: HY-18102
CAS No.: 1215085-92-9
Target:
연구분야:
GLPG0492 is an orally active, non-steroidal selective androgen receptor modulator. GLPG0492 exerts functional transactivation by binding to the ligand-binding domain of the receptor, exhibiting preferential partial agonist activity in muscle and bone tissues with low activity in reproductive tissues. GLPG0492 effectively counteracts muscle atrophy-related pathways, significantly enhances muscle strength, maintains motor ability, reduces fibrosis and improves electrophysiological parameters. GLPG0492 prevents immobilization-induced muscle atrophy and regulates muscle mass homeostasis, serving as a valuable tool compound for studies on Duchenne muscular dystrophy, muscle loss and various types of disuse musculoskeletal atrophy .
7
7 Cited Publications
Target:
연구분야:
NF449 octasodium is a highly potent P2X1 receptor antagonist, with IC50s of 0.28, 0.69, and 120 nM for rP2X1, rP2X1+5, P2X2+3, respectively. NF449 octasodium is a Gsα-selective G Protein antagonist. NF449 octasodium suppresses the rate of GTP[γS] binding to Gsα-s, inhibits the stimulation of adenylyl cyclase activity, and blocks the coupling of β-adrenergic receptors to Gs .
5
5 Cited Publications
Target:
연구분야:
SBI-425 is an orally active and potent TNAP (tissue-nonspecific alkaline phosphatase) inhibitor (IC50=16 nM). SBI-425 inhibits TNAP in the vasculature, improving cardiovascular parameters and survival .
5
3
Target:
연구분야:
3
3 Cited Publications
Cat. No.: HY-P2141A
Target:
연구분야:
2
2 Cited Publications
Cat. No.: HY-N4170
CAS No.: 23725-05-5
2
Target:
연구분야:
Galactose Oxidase, Dactylium dendroides (GOase) from fungus is often used in biochemical studies. Galactose oxidase is a type II copper metalloenzyme, and it containing a single polypeptide. Galactose oxidase catalyzes two-electron oxidation of primary alcohols to their corresponding aldehydes, coupling with the reduction of dioxygen to hydrogen peroxide .
2
2 Cited Publications
Cat. No.: HY-B0558
CAS No.: 22232-54-8
Target:
Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .
2
2 Cited Publications
Synonyms: 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride
1
1 Cited Publications
Cat. No.: HY-D2171A
1
1 Cited Publications
Cat. No.: HY-161541
1
Target:
1
1 Cited Publications
Cat. No.: HY-15933
CAS No.: 40567-80-4
1
1 Cited Publications
Cat. No.: HY-30014
CAS No.: 348640-06-2
1
1 Cited Publications
Cat. No.: HY-P99205
CAS No.: 1020264-78-1
Target:
연구분야:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
