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Pathways Recommended:	Metabolic Enzyme/Protease

Results for "

serine protease enzyme

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Protease Activated Receptor (PAR) (2) Ser/Thr Protease (10) Apoptosis (1) Biochemical Assay Reagents (1) Cathepsin (1) Endogenous Metabolite (1) Factor XI (1) Fluorescent Dye (1) Furin (2) Kallikrein (1) Phosphatase (1) Wnt (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (4) Infection (7) Inflammation/Immunology (4) Metabolic Disease (2) Neurological Disease (2)

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Natural
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Recombinant Proteins

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Art. -Nr.	Produktname	Target	Forschungsgebiete	Chemical Structure

HY-B0496

PMSF Maximum Cited Publications 146 Publications Verification Phenylmethylsulfonyl fluoride; Benzylsulfonyl fluoride	Cathepsin Ser/Thr Protease	Neurological Disease
PMSF (Phenylmethylsulfonyl fluoride) is a nonspecific and irreversible **serine proteases** inhibitor. PMSF inhibits some thiol proteases, non-protease enzymes, and acetylcholinesterase. PMSF can be used to prepare protein extracts from tissue and cell lysates .

HY-129047

Trypsin 15+ Cited Publications	Ser/Thr Protease Protease Activated Receptor (PAR)	Infection Inflammation/Immunology
Trypsin is a serine protease enzyme, and hydrolyzes proteins at the carboxyl side of the Lysine or Arginine. Trypsin activates PAR2 and PAR4. Trypsin induces cell-to-cell membrane fusion in PDCoV infection by the interaction of S glycoprotein of PDCoV and pAPN. Trypsin also promotes cell proliferation and differentiation. Trypsin can be used in the research of wound healing and neurogenic inflammation .

HY-129047A

Trypsin (MS grade)	Ser/Thr Protease Protease Activated Receptor (PAR)	Infection Inflammation/Immunology
Trypsin MS grade is a serine protease enzyme, and hydrolyzes proteins at the carboxyl side of the Lysine or Arginine. Trypsin MS grade activates PAR2 and PAR4. Trypsin MS grade induces cell-to-cell membrane fusion in PDCoV infection by the interaction of S glycoprotein of PDCoV and pAPN. Trypsin MS grade also promotes cell proliferation and differentiation. Trypsin MS grade can be used in the research of wound healing and neurogenic inflammation .

HY-B2228

Proteinase, Aspergillus oryzae 1 Publications Verification	Biochemical Assay Reagents	Cancer
Proteinase, Aspergillus oryzae is a serine protease that hydrolyzes peptide bonds in protein substrates, preferring alkaline conditions (optimal pH 10.5). It efficiently degrades casein, poly-L-glutamic acid, and poly-L-lysine, with activity irreversibly inhibited by diisopropylfluorophosphate (DFP) and potato inhibitor. This enzyme catalyzes proteolysis via serine residues in its active site, finding applications in food processing (e.g., soy sauce fermentation), detergents, and leather industries due to its high yield in solid-state fermentation and cost-effective production.

HY-E70203

Recombinant aprotinin	Ser/Thr Protease	Cardiovascular Disease Inflammation/Immunology
Recombinant aprotinin is a serine protease inhibitor. Recombinant aprotinin can inhibit trypsin and related proteolytic enzymes .

HY-126034

3,4-Dichloroisocoumarin	Ser/Thr Protease Apoptosis	Cardiovascular Disease Metabolic Disease Cancer
3,4-Dichloroisocoumarin is a potent *serine-protease* and SrLip inhibitor (K_i for SrLip: 26.6 μM). 3,4-Dichloroisocoumarin is opened by serine proteases and then undergoes acylation with the enzyme, thereby inhibiting protease activity. 3,4-Dichloroisocoumarin can induce DNA fragmentation and Apoptosis. 3,4-Dichloroisocoumarin can be used in the research of multiple fields such as tumors, cardiovascular disease and enzyme catalytic mechanisms .

HY-E70392

Recombinant Trypsin	Ser/Thr Protease	Others
Recombinant Trypsin is a serine protease enzyme, and hydrolyzes proteins at the carboxyl side of the Lysine or Arginine .

HY-P5062A

DEC-RVRK-CMK TFA Decanoyl-Arg-Val-Arg-Lys-chloromethylketone TFA	Furin	Infection
DEC-RVRK-CMK (Decanoyl-Arg-Val-Arg-Lys-chloromethylketone) TFA is a peptide-based CMK (chloromethylketone) inhibitor that targets and inactivates the secreted soluble kexin (Kex2) (K_i=8.45 μM). The yeast enzyme Kex2 (kexin, EC 3.4.21.61) is a calcium-dependent transmembrane protease and belongs to the mammalian protease family of the serine protease subtilisin family. The binding mechanism of Kex2 with different CMK inhibitors depends on substrate selectivity, particularly the selective differences between lysine and arginine at the P1 position .

HY-P4496

Tos-Gly-Pro-Lys-pNA	Phosphatase	Others
Tos-Gly-Pro-Lys-pNA is a substrate for the serine protease ALP and can be used to measure the activity of this enzyme .

HY-P3947

Fluorescent Substrate for Subtillsin	Ser/Thr Protease	Infection
Fluorescent Substrate for Subtillsin can be used to detect the enzyme activity of subtillsin. Subtilisin is a bacterial serine protease .

HY-P5062

DEC-RVRK-CMK Decanoyl-Arg-Val-Arg-Lys-chloromethylketone	Furin	Infection
DEC-RVRK-CMK (Decanoyl-Arg-Val-Arg-Lys-chloromethylketone) is a peptide-based CMK (chloromethylketone) inhibitor that targets and inactivates the secreted soluble kexin (Kex2) (K_i=8.45 μM). The yeast enzyme Kex2 (kexin, EC 3.4.21.61) is a calcium-dependent transmembrane protease and belongs to the mammalian protease family of the serine protease subtilisin family. The binding mechanism of Kex2 with different CMK inhibitors depends on substrate selectivity, particularly the selective differences between lysine and arginine at the P1 position .

HY-150519

FXIa/Plasma kallikrein-IN-1	Factor XI Kallikrein	Cardiovascular Disease
FXIa/Plasma kallikrein-IN-1 is an inhibitor of coagulation factor XIa (FXIa) and plasma kallikrein with K_i values of 187.70 nM and 151.6 nM, respectively. FXIa/Plasma kallikrein-IN-1 can be used in the research of thromboembolic diseases .

HY-161370

VD4162	Ser/Thr Protease	Cancer
VD4162 (Compound 8b) is a macrocyclic inhibitor of **serine proteases*. VD4162 can significantly improve potency for all four target enzymes* TMPRSS2 (IC₅₀ = 3.7 nM), HGFA(IC₅₀ = 3.3 nM), matriptase (IC₅₀ = 2.9 nM), and hepsin (IC₅₀ = 0.54 nM). VD4162 can be used for the research of cancer .

HY-E70390

C1s Enzyme masp-2, c1 esterase, c1-esterase	Wnt	Cardiovascular Disease Inflammation/Immunology
C1s Enzyme is a subunit of the complement C1 complex, which activates the complement as a serine protease. C1s Enzyme cleaves LRP5 and LRP6, and thus activates the Wnt/β-Catenin signaling pathway. C1s Enzyme promotes the macrophage M2 polarization and inhibits M1 polarization. C1s Enzyme enhances efferocytosis, exhibits anti-inflammatory activity .

HY-105747A

Guanoxyfen nitrate N-(3-Phenoxypropyl)guanidine nitrate; (3-Phenoxypropyl)guanidine nitrate	Endogenous Metabolite	Infection Neurological Disease
Guanoxyfen (N-(3-Phenoxypropyl)guanidine) nitrate is a compound that exhibits potent inhibitory activity against the serine protease enzyme TMPRSS2, which plays a crucial role in the infectivity of coronaviruses. Guanoxyfen nitrate is also an effective inhibitor of vasoconstrictor responses to sympathetic nerve stimulation.

HY-P11367

Boc-Ala-Gly-Pro-Arg-AMC	Fluorescent Dye Ser/Thr Protease	Infection Metabolic Disease
Boc-Ala-Gly-Pro-Arg-AMC is a synthetic fluorescent substrate, widely used for the detection of protease activity. Boc-Ala-Gly-Pro-Arg-AMC can be used to detect the activity of serine proteases and the oligopeptide enzyme B of Trypanosoma brucei .

HY-N19612

Proteasefrom aspergillus oryzae	Ser/Thr Protease	Others
Proteasefrom aspergillus oryzae is a serine protease identified in the non-transgenic Aspergillus ochraceus strain AE-P. Proteasefrom aspergillus oryzae functions as a food enzyme and catalyzes protein hydrolysis with broad-spectrum specificity .

Art. -Nr.	Produktname	Type

HY-B2228

Proteinase, Aspergillus oryzae 1 Publications Verification	Biochemical Assay Reagents
Proteinase, Aspergillus oryzae is a serine protease that hydrolyzes peptide bonds in protein substrates, preferring alkaline conditions (optimal pH 10.5). It efficiently degrades casein, poly-L-glutamic acid, and poly-L-lysine, with activity irreversibly inhibited by diisopropylfluorophosphate (DFP) and potato inhibitor. This enzyme catalyzes proteolysis via serine residues in its active site, finding applications in food processing (e.g., soy sauce fermentation), detergents, and leather industries due to its high yield in solid-state fermentation and cost-effective production.

Proteinase, Aspergillus oryzae

1 Publications Verification

Biochemical Assay Reagents

Proteinase, Aspergillus oryzae is a serine protease that hydrolyzes peptide bonds in protein substrates, preferring alkaline conditions (optimal pH 10.5). It efficiently degrades casein, poly-L-glutamic acid, and poly-L-lysine, with activity irreversibly inhibited by diisopropylfluorophosphate (DFP) and potato inhibitor. This enzyme catalyzes proteolysis via serine residues in its active site, finding applications in food processing (e.g., soy sauce fermentation), detergents, and leather industries due to its high yield in solid-state fermentation and cost-effective production.

Art. -Nr.	Produktname	Target	Research Area

HY-P5062A

DEC-RVRK-CMK TFA Decanoyl-Arg-Val-Arg-Lys-chloromethylketone TFA	Furin	Infection
DEC-RVRK-CMK (Decanoyl-Arg-Val-Arg-Lys-chloromethylketone) TFA is a peptide-based CMK (chloromethylketone) inhibitor that targets and inactivates the secreted soluble kexin (Kex2) (K_i=8.45 μM). The yeast enzyme Kex2 (kexin, EC 3.4.21.61) is a calcium-dependent transmembrane protease and belongs to the mammalian protease family of the serine protease subtilisin family. The binding mechanism of Kex2 with different CMK inhibitors depends on substrate selectivity, particularly the selective differences between lysine and arginine at the P1 position .

HY-P4496

Tos-Gly-Pro-Lys-pNA	Phosphatase	Others
Tos-Gly-Pro-Lys-pNA is a substrate for the serine protease ALP and can be used to measure the activity of this enzyme .

HY-P3947

Fluorescent Substrate for Subtillsin	Ser/Thr Protease	Infection
Fluorescent Substrate for Subtillsin can be used to detect the enzyme activity of subtillsin. Subtilisin is a bacterial serine protease .

HY-P5062

DEC-RVRK-CMK Decanoyl-Arg-Val-Arg-Lys-chloromethylketone	Furin	Infection
DEC-RVRK-CMK (Decanoyl-Arg-Val-Arg-Lys-chloromethylketone) is a peptide-based CMK (chloromethylketone) inhibitor that targets and inactivates the secreted soluble kexin (Kex2) (K_i=8.45 μM). The yeast enzyme Kex2 (kexin, EC 3.4.21.61) is a calcium-dependent transmembrane protease and belongs to the mammalian protease family of the serine protease subtilisin family. The binding mechanism of Kex2 with different CMK inhibitors depends on substrate selectivity, particularly the selective differences between lysine and arginine at the P1 position .

HY-P11367

Boc-Ala-Gly-Pro-Arg-AMC	Fluorescent Dye Ser/Thr Protease	Infection Metabolic Disease
Boc-Ala-Gly-Pro-Arg-AMC is a synthetic fluorescent substrate, widely used for the detection of protease activity. Boc-Ala-Gly-Pro-Arg-AMC can be used to detect the activity of serine proteases and the oligopeptide enzyme B of Trypanosoma brucei .

Art. -Nr.	Produktname	Category	Target	Chemical Structure

HY-126034

3,4-Dichloroisocoumarin	Animals Coumarins Phenylpropanoids Source Classification	Ser/Thr Protease Apoptosis
3,4-Dichloroisocoumarin is a potent *serine-protease* and SrLip inhibitor (K_i for SrLip: 26.6 μM). 3,4-Dichloroisocoumarin is opened by serine proteases and then undergoes acylation with the enzyme, thereby inhibiting protease activity. 3,4-Dichloroisocoumarin can induce DNA fragmentation and Apoptosis. 3,4-Dichloroisocoumarin can be used in the research of multiple fields such as tumors, cardiovascular disease and enzyme catalytic mechanisms .

HY-N19612

Proteasefrom aspergillus oryzae	Structural Classification Natürliche Produkte Microorganisms Source Classification	Ser/Thr Protease
Proteasefrom aspergillus oryzae is a serine protease identified in the non-transgenic Aspergillus ochraceus strain AE-P. Proteasefrom aspergillus oryzae functions as a food enzyme and catalyzes protein hydrolysis with broad-spectrum specificity .

Species:	Human (1) Mouse (1)
Tag:	His (2) Tag Free (1)
Source:	HEK293 (2) E. coli (1)

Art. -Nr.	Compare	Produktname	Species	Source	Image

HY-P70883

	Kallikrein-7 Protein, Mouse (HEK293, His) Kallikrein-7; Klk7; serine protease 6; Stratum corneum chymotryptic enzyme; Thymopsin; kallikrein-related peptidase 7; PRSS6; SCCEkallikrein-7	Mouse	HEK293
	Kallikrein-7 is an important contributor to skin integrity and may catalyze the degradation of intercellular adhesive structures that are critical for continuous cell shedding.Kallikrein-7 exhibits cleavage activity against insulin A and B chains, with specificity for aromatic residues at position P1 indicating versatility in substrate recognition.Kallikrein-7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Kallikrein-7 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70163

	Kallikrein-7 Protein, Human (HEK293, His, solution) rHuKallikrein 7/KLK7, His ; Kallikrein-7; hK7; serine protease 6; Stratum Corneum Chymotryptic enzyme; hSCCE; KLK7; PRSS6; SCCE	Human	HEK293
	Kallikrein-7 Protein (KLK7), a member of the tissue kallikrein family, is a first protease target of vaspin inhibited by classical serpin mechanism with high specificity in vitro. KLK7 cleaves human insulin in the A- and B-chain. KLK7 a serine protease with chymotrypsin-like activity which was involved in the regulated desquamation of terminally differentiated keratinocytes. KLK7 mediates the disruption of corneodesmosomes, the cell–cell adhesion junctions of corneocyites, by hydrolyzing the two mayor cadherins (corneodesmosin and desmocollin 1) in the extracellular region of these junctions. KLK7 overexpression and/or increased activity result in over-desquamation. Kallikrein-7 Protein, Human (HEK293, His, solution) is the recombinant human-derived Kallikrein-7 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P703547

	HCVNS5B Protein, HCV Genome polyprotein; Hepatitis C virus genotype 1b (strain HC-J4); HCV; p23; Helicase; Hydrolase; Ion channel; Multifunctional enzyme; Nucleotidyltransferase; protease; Ribonucleoprotein; RNA-binding; RNA-directed RNA polymerase; serine protease; Thiol protease; Transferase; Viral ion channel; Viral nucleoprotein	Others	E. coli
	POLG proteins play multiple roles in the viral life cycle, contributing to viral RNA packaging, budding, and particle production. It exhibits RNA-binding and RNA chaperone activities, affecting translation initiation through interactions with viral IRES and ribosomal subunits. HCVNS5B Protein, HCV is the recombinant HCVNS5B, expressed by E. coli, with tag-free.

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Host:	Rabbit (2)
Reactivity:	Human (2)
Application:	WB (2)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (1)
Modification:	Unmodified (1)

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HY-P86673

	FAP Antibody (YA6365) Prolyl endopeptidase FAP; FAPA; Fibroblast activation protein, alpha; 170 kDa melanoma membrane bound gelatinase; 170 kDa melanoma membrane-bound gelatinase; DPPIV; Fibroblast activation protein alpha; Integral membrane serine protease; SEPR_HUMAN; 170 kDa melanoma membrane-bound gelatinase; Dipeptidyl peptidase FAP; FAPalpha; Gelatine degradation protease FAP; Integral membrane serine protease; Post-proline cleaving enzyme; serine integral membrane protease; SIMP; Surface-expressed protease; Seprase; Antiplasmin-cleaving enzyme FAP, soluble form; APCE.	WB	Human
	FAP Antibody (YA6365) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FAP.

HY-P86673A

	FAP Antibody (YA6365)(PBS only) Prolyl endopeptidase FAP; FAPA; Fibroblast activation protein, alpha; 170 kDa melanoma membrane bound gelatinase; 170 kDa melanoma membrane-bound gelatinase; DPPIV; Fibroblast activation protein alpha; Integral membrane serine protease; SEPR_HUMAN; 170 kDa melanoma membrane-bound gelatinase; Dipeptidyl peptidase FAP; FAPalpha; Gelatine degradation protease FAP; Integral membrane serine protease; Post-proline cleaving enzyme; serine integral membrane protease; SIMP; Surface-expressed protease; Seprase; Antiplasmin-cleaving enzyme FAP, soluble form; APCE.	WB	Human
	FAP Antibody (YA6365) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FAP.

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serine protease enzyme

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