33 Results for "

serine protease enzyme

" in MedChemExpress (MCE) Product Catalog:
Products (33)

33 Results for "serine protease enzyme" in MCE Product Catalog:

163
163 Publications Verification
Cat. No.: HY-B0496
CAS No.: 329-98-6
Synonyms: Phenylmethylsulfonyl fluoride; Benzylsulfonyl fluoride
Research Areas:  

Neurological Disease

PMSF (Phenylmethylsulfonyl fluoride) is a nonspecific and irreversible serine proteases inhibitor. PMSF inhibits some thiol proteases, non-protease enzymes, and acetylcholinesterase. PMSF can be used to prepare protein extracts from tissue and cell lysates .
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27
27 Cited Publications
Cat. No.: HY-129047
CAS No.: 9002-07-7
Purity:  91.00%
Trypsin is a serine protease enzyme, and hydrolyzes proteins at the carboxyl side of the Lysine or Arginine. Trypsin activates PAR2 and PAR4. Trypsin induces cell-to-cell membrane fusion in PDCoV infection by the interaction of S glycoprotein of PDCoV and pAPN. Trypsin also promotes cell proliferation and differentiation. Trypsin can be used in the research of wound healing and neurogenic inflammation .
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9
9 Cited Publications
Cat. No.: HY-114164H
CAS No.: 9002-04-4
Synonyms: EC 3.4.21.5 (Lyophilized); Human Alpha Thrombin (Lyophilized)
Human α-Thrombin (EC 3.4.21.5; Human Alpha Thrombin) (Lyophilized) is a terminal serine protease in the coagulation cascade, as well as a potent physiological platelet agonist and fibrin-generating enzyme in vivo. Human α-Thrombin catalyzes the conversion of fibrinogen to fibrin for blood clot formation, and activates platelet aggregation by cleaving the protease-activated receptors PAR1 (major) (Kd = 1 nM) and PAR4 (minor) on the platelet surface to expose tethered ligands. Human α-Thrombin also amplifies coagulation via positive feedback by activating coagulation factors V, VIII, XI (FV/FVIII/FXI), and switches to activate protein C to exert anticoagulant effects after binding to thrombomodulin .
This product is in a freeze-dried form.
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2
2 Cited Publications
Cat. No.: HY-P72659A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FAP; Prolyl Endopeptidase FAP; Fibroblast Activation Protein Alpha; Dipeptidyl Peptidase FAP; Seprase; FAPalpha; DPPIV; SIMP; 170 KDa Melanoma Membrane-Bound Gelatinase; CDNA FLJ60298, Highly Similar To Seprase; Gelatine Degradation protease FAP; Fibroblast Activation Protein, Alpha; Integral Membrane serine protease; serine Integral Membrane protease; Post-Proline Cleaving enzyme; FAPA; Surface-Expressed protease
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-B2228
CAS No.: 9001-92-7
Proteinase, Aspergillus oryzae is a serine protease that hydrolyzes peptide bonds in protein substrates, preferring alkaline conditions (optimal pH 10.5). It efficiently degrades casein, poly-L-glutamic acid, and poly-L-lysine, with activity irreversibly inhibited by diisopropylfluorophosphate (DFP) and potato inhibitor. This enzyme catalyzes proteolysis via serine residues in its active site, finding applications in food processing (e.g., soy sauce fermentation), detergents, and leather industries due to its high yield in solid-state fermentation and cost-effective production.
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1
1 Cited Publications
Cat. No.: HY-123275A
CAS No.: 160192-34-7
Purity:  99.40%
Synonyms: S-2238 hydrochloride
Target:  

Thrombin

Research Areas:  

Others

H-D-Phe-Pip-Arg-pNA hydrochloride (S-2238 hydrochloride) is a specific chromogenic peptide substrate for thrombin (Thrombin). The amide bond of H-D-Phe-Pip-Arg-pNA hydrochloride is rapidly hydrolyzed by thrombin, producing a characteristic yellow absorbance at 405 nm, and the change in absorbance is proportional to thrombin activity. H-D-Phe-Pip-Arg-pNA hydrochloride can be used in biochemical detection-related studies .
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1
1 Cited Publications
Cat. No.: HY-123275B
CAS No.: 115388-96-0
Purity:  98.90%
Synonyms: S-2238 acetate
Target:  

Thrombin

Research Areas:  

Others

H-D-Phe-Pip-Arg-pNA acetate (S-2238 acetate) is a specific chromogenic peptide substrate for thrombin (Thrombin). The amide bond of H-D-Phe-Pip-Arg-pNA acetate is rapidly hydrolyzed by thrombin, producing a characteristic yellow absorbance at 405 nm, and the change in absorbance is proportional to thrombin activity. H-D-Phe-Pip-Arg-pNA acetate can be used in biochemical detection-related studies .
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1
1 Cited Publications
Cat. No.: HY-123275
CAS No.: 64815-81-2
Synonyms: S-2238
Target:  

Thrombin

Research Areas:  

Others

H-D-Phe-Pip-Arg-pNA (S-2238) is a specific chromogenic peptide substrate for thrombin (Thrombin). The amide bond of H-D-Phe-Pip-Arg-pNA is rapidly hydrolyzed by thrombin, producing a characteristic yellow absorbance at 405 nm, and the change in absorbance is proportional to thrombin activity. H-D-Phe-Pip-Arg-pNA can be used in biochemical detection-related studies .
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Cat. No.: HY-129047A
CAS No.: 9002-07-7
Trypsin MS grade is a serine protease enzyme, and hydrolyzes proteins at the carboxyl side of the Lysine or Arginine. Trypsin MS grade activates PAR2 and PAR4. Trypsin MS grade induces cell-to-cell membrane fusion in PDCoV infection by the interaction of S glycoprotein of PDCoV and pAPN. Trypsin MS grade also promotes cell proliferation and differentiation. Trypsin MS grade can be used in the research of wound healing and neurogenic inflammation .
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Cat. No.: HY-E70203
CAS No.: 9087-70-1
Recombinant aprotinin is a serine protease inhibitor. Recombinant aprotinin can inhibit trypsin and related proteolytic enzymes .
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Cat. No.: HY-E70544B
CAS No.: 9001-29-0
Canine Factor X is a vitamin K-dependent plasma serine protease that is activated to generate Factor Xa. Canine Factor X mediates the common coagulation pathway and catalyzes the conversion of prothrombin to thrombin . Canine Factor X is the first enzyme to act in the common pathway of thrombosis in the coagulation cascade. Canine Factor X can be used in studies related to Factor X deficiency .
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Cat. No.: HY-126034
CAS No.: 51050-59-0
Purity:  99.72%
3,4-Dichloroisocoumarin is a potent serine-protease and SrLip inhibitor (Ki for SrLip: 26.6 μM). 3,4-Dichloroisocoumarin is opened by serine proteases and then undergoes acylation with the enzyme, thereby inhibiting protease activity. 3,4-Dichloroisocoumarin can induce DNA fragmentation and Apoptosis. 3,4-Dichloroisocoumarin can be used in the research of multiple fields such as tumors, cardiovascular disease and enzyme catalytic mechanisms .
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Cat. No.: HY-E70392
Target:  

Ser/Thr Protease

Research Areas:  

Others

Recombinant Trypsin is a serine protease enzyme, and hydrolyzes proteins at the carboxyl side of the Lysine or Arginine .
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Cat. No.: HY-123275C
CAS No.: 62354-65-8
Synonyms: S-2238 dihydrochloride
Target:  

Thrombin

Research Areas:  

Others

H-D-Phe-Pip-Arg-pNA dihydrochloride (S-2238 dihydrochloride) is a specific chromogenic peptide substrate for thrombin (Thrombin). The amide bond of H-D-Phe-Pip-Arg-pNA dihydrochloride is rapidly hydrolyzed by thrombin, producing a characteristic yellow absorbance at 405 nm, and the change in absorbance is proportional to thrombin activity. H-D-Phe-Pip-Arg-pNA dihydrochloride can be used in biochemical detection-related studies .
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Cat. No.: HY-P5062A
Synonyms: Decanoyl-Arg-Val-Arg-Lys-chloromethylketone TFA
Target:  

Furin

Research Areas:  

Infection

DEC-RVRK-CMK (Decanoyl-Arg-Val-Arg-Lys-chloromethylketone) TFA is a peptide-based CMK (chloromethylketone) inhibitor that targets and inactivates the secreted soluble kexin (Kex2) (Ki=8.45 μM). The yeast enzyme Kex2 (kexin, EC 3.4.21.61) is a calcium-dependent transmembrane protease and belongs to the mammalian protease family of the serine protease subtilisin family. The binding mechanism of Kex2 with different CMK inhibitors depends on substrate selectivity, particularly the selective differences between lysine and arginine at the P1 position .
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Cat. No.: HY-P4496
CAS No.: 73392-19-5
Target:  

Phosphatase

Research Areas:  

Others

Tos-Gly-Pro-Lys-pNA is a substrate for the serine protease ALP and can be used to measure the activity of this enzyme .
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Cat. No.: HY-P3947
CAS No.: 147471-56-5
Target:  

Ser/Thr Protease

Research Areas:  

Infection

Fluorescent Substrate for Subtillsin can be used to detect the enzyme activity of subtillsin. Subtilisin is a bacterial serine protease .
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Cat. No.: HY-P5062
CAS No.: 534615-50-4
Synonyms: Decanoyl-Arg-Val-Arg-Lys-chloromethylketone
Target:  

Furin

Research Areas:  

Infection

DEC-RVRK-CMK (Decanoyl-Arg-Val-Arg-Lys-chloromethylketone) is a peptide-based CMK (chloromethylketone) inhibitor that targets and inactivates the secreted soluble kexin (Kex2) (Ki=8.45 μM). The yeast enzyme Kex2 (kexin, EC 3.4.21.61) is a calcium-dependent transmembrane protease and belongs to the mammalian protease family of the serine protease subtilisin family. The binding mechanism of Kex2 with different CMK inhibitors depends on substrate selectivity, particularly the selective differences between lysine and arginine at the P1 position .
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Cat. No.: HY-150519
CAS No.: 1551460-43-5
Target:  

Factor XI Kallikrein

Research Areas:  

Cardiovascular Disease

FXIa/Plasma kallikrein-IN-1 is an inhibitor of coagulation factor XIa (FXIa) and plasma kallikrein with Ki values of 187.70 nM and 151.6 nM, respectively. FXIa/Plasma kallikrein-IN-1 can be used in the research of thromboembolic diseases .
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Cat. No.: HY-161370
CAS No.: 2574390-19-3
Target:  

Ser/Thr Protease

Research Areas:  

Cancer

VD4162 (Compound 8b) is a macrocyclic inhibitor of serine proteases. VD4162 can significantly improve potency for all four target enzymes TMPRSS2 (IC50 = 3.7 nM), HGFA(IC50 = 3.3 nM), matriptase (IC50 = 2.9 nM), and hepsin (IC50 = 0.54 nM). VD4162 can be used for the research of cancer .
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